检索结果-南通市图书馆

Facile design of Au@Pt core-shell nanostructures： Formation of Pt submonolayers with tunable coverage and their applications in electrocatalysis

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nano Research 2014年第3期7卷 410-417页

作者： Fulin Zheng wing-tak wong Ka-Fu Yung Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic University Hung Hom Hong Kong SAR China

A facile design of Pt nanostructures from submonolayer to monolayer has been realized by ion adsorption-in situ electrochemical reduction on Au nanoparticles supported on multiwall carbon nanotubes （CNTs）. The as prepared Au@Pt/CNTs catalysts display coverage-specific electrocatalysis. Au@Pt/CNTs with low Pt coverage is inactive towards methanol oxidation whereas it oxidizes formic acid effectively through a direct pathway with mass specific activity 90 times that of a commercial Pt/C catalyst. Due to its inertness to methanol, it shows high performance in the oxygen reduction reaction （ORR） with high methanol tolerance. In contrast, simply increasing the Pt coverage to above 40% switches the formic acid oxidation process to both direct and indirect catalytic pathways, and also results in high methanol oxidation activity.

关键词： electrocatalysis platinum submonolayer fuel cell

Rapid testing methods for food contaminants and toxicants

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2015年第11期14卷 2243-2264页

作者： Jiachi Chiou Arthur Ho Hon Leung Hang Wai Lee wing-tak wong Department of Applied Biology and Chemical Technology Food Safety and Technology Research CenterThe Hong Kong Polytechnic University Shenzhen Key Laboratory for Food Biological Safety Control Food Safety and Technology Research CentreThe Hong Kong Polytechnic University Shenzhen Research Institute

Food safety is one of the major concerns in every country regardless of the economic and social development. The frequent occurrence of food scandals in the world has led the Chinese government to implement several strategies to fortify the food supply system to a high food safety standard. This relies heavily on laboratory testing services but conventional methods for detection of food contaminants and toxicants are limited by sophisticated sample preparation procedures, long analysis time, large instruments and professional personnel to meet the increasing demands. In this review, we have incorporated most of the current and potential rapid detection methods for many notorious food contaminants and toxicants including microbial agents, toxic ions, pesticides, veterinary drugs and preservatives, as well as detection of genetically modified food genes and adulterated edible oil. Development of rapid, accurate, easy-to-use and affordable testing methods could urge food handlers and the public to actively screen for food contaminants and toxicants instead of passively relying on monitoring by the government examination facility. This review also provides several recommendations including how to encourage the public to engage in the food safety management system and provide optimal education and financial assistance that may improve the current Chinese food safety control system.

关键词： rapid testing food contaminants and toxins microbial agents pesticides veterinary drugs preservatives formaldehyde nitrite nitrate test strips

Intramolecular (4+3) cycloadditions of nitrogen-tethered epoxy enosilanes for the synthesis of heteropolycycles

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2019年第8期30卷 1523-1526页

作者： Jiayun He Shuk Mei Lam Jerome PLNg wing-tak wong Pauline Chiu State Key Laboratory of Synthetic Chemistry Department of ChemistryThe University of Hong KongHong KongChina Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic UniversityHong KongChina

Furans bearing epoxy enolsilane units via a tether that incorporates a nitrogen heteroatom,undergo intramolecular(4+3)cycloadditions to generate bis-heteroatomic polycyclic adducts having piperidine moieties in their *** cycloadducts,ultimately derived from furfural,a renewal chemical feedstock,are obtained with up to 4:1 dr and with ee retained from the epoxide.

关键词： Heterocycles (4+3)cycloaddition Furan Intramolecular Epoxides Piperidine Polycyclic compounds

Crocodile blood supplementation protect svascular function in diabetic mice

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Food Production, Processing and Nutrition 2021年第1期3卷 283-295页

作者： Chui Yiu Bamboo Chook Francis M.Chen Gary Tse Fung Ping Leung wing tak wong School of Life Sciences Faculty of ScienceThe Chinese University of Hong KongShatinNTHong Kong SAR State Key Laboratory of Agrobiotechnology The Chinese University of Hong KongHong KongChina

Cardiovascular disease is a major cause of mortality in diabetic patients due to the heightened oxidative stress and pro-inflammatory state in vascular *** approaches targeting cardiovascular health for diabetic patients are urgently *** blood,an emerging dietary supplement,was suggested to have anti-oxidative and anti-inflammatory effects in vitro,which have yet to be proven in animal *** study thereby aimed to evaluate whether crocodile blood can protect vascular function in diabetic mice against oxidation and *** db/db mice and their counterparts db/m+mice were treated daily with crocodile blood soluble fraction(CBSF)or vehicle via oral gavage for 4 weeks before their aortae were harvested for endothelium-dependent relaxation(EDR)quantification using wire myograph,which is a well-established functional study for vascular function *** culture experiments culturing mouse aortae from C57BL/6 J mice with or without IL-1βand CBSF were done to evaluate the direct effect of CBSF on endothelial *** oxygen species(ROS)levels in mouse aortae were assessed by dihydroethidium(DHE)staining with inflammatory markers in endothelial cells quantified by quantitative polymerase chain reaction(qPCR).CBSF significantly improved deteriorated EDR in db/db diabetic mice through both diet supplementation and direct culture,with suppression of ROS level in mouse *** also maintained EDR and reduced ROS levels in mouse aortae against the presence of pro-inflammatory IL-1β.Under the pro-inflammatory state induced by IL-1β,gene expressions of inflammatory cytokines were downregulated,while the protective transcripts UCP2 and SIRT6 were upregulated in endothelial *** study suggests a novel beneficial effect of crocodile blood on vascular function in diabetic mice and that supplementation of diet with crocodile blood may act as a complementary approach to protect against vascular diseases through anti

关键词： Crocodile blood Diabetes mellitus Vascular endothelial function Anti-oxidative Anti-inflammatory

Inhibition of bone morphogenic protein-4 improves the endothelial function through reduction of oxidative stress in type 2 diabetic mice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Inhibition of bone morphogenic protein-4 improves the endoth...

Regular running exercise reverses diabetes-related endothelium dysfunction by reducing endoplasmic reticulum stress

第八届海峡两岸心血管科学研讨会

作者： wing tak wong Institute of Vascular Medicine School of Biomedical Sciencesthe Chinese University of Hong KongShatinNT.Hong KongChina

Objective Bone morphogenic protein(BMP4) stimulates superoxide production and exerts proinflammatory effects in the ***4 also mediates endothelial dysfunction in ***, the role of BMP4 in endothelial dysfunction of type 2 diabetes remains *** present study aims to investigate whether inhibition of BMP4 can improve the endothelial function of type 2 diabetic mice,and to study the mechanism underlying BMP4 - induced oxidative stress in *** Endothelium - dependent relaxation(EDR) of arteries was assessed in wire *** chronic treatment,db/db mice were infused subcutaneously by BMP4 inhibitor noggin(0.4 mg/kg/day) or vehicle through osmotic pump for two weeks, and vasoreactivities of mouse aortae and mesenteric arteries were *** addition,isolated aortae of db/ db mice were treated with three different BMP4 inhibitors including noggin,chordin,and follistatin for 24 hours in ex vivo organ culture and EDRs were measured *** expressions were examined by Western *** oxidative species(ROS) in both aortic endothelium and cultured endothelial cells were measured by dihydroethidium(DHE) and CM -HDCFDA fluorescence under confocal *** BMP4 expression increased in db/db mouse aortae compared with that in db/*** of noggin in db/db mice reduced systolic blood pressure[(101.7±4.0) mmHg]compared with that of control db/db mice[(120.9±3.1) mmHg]without affecting the insulin and glucose *** addition,the acetylcholine -induced endothelium-dependent relaxation in both aortae and resistance mesenteric arteries improved after noggin infusion in db/db *** with noggin,chordin,or follistatin for 24 hours improved EDRs in db/db mouse *** production measured by DHE or GM - HDCFDA fluorescence was reduced by BMP4 inhibitors in en face endothelium of db/db mouse ***4 treatment also increased ROS production in both en face endothelium of C57BL/6J mice a

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Regular running exercise reverses diabetes-related endotheli...

Spontaneous type 1 pattern, ventricular arrhythmias and sudden cardiac death in Brugada Syndrome： an updated systematic review and meta-analysis

第八届海峡两岸心血管科学研讨会

作者： wing tak wong Li Ka Shing Institute of Health Sciences Institute of Vascular Medicineand School of Biomedical SciencesChinese University of Hong KongHong KongChina

Objectives Endoplasmic reticulum(ER) stress is demonstrated as a key link amongst insulin resistance, type 2 diabetes and *** has been shown to restore endothelial functions with an increase of 5 - monophosphate protein kinase(AMPK) *** present study investigated whether exercise training could ameliorate endothelial function in db/db mice and diet - induced obese mice by reducing ER stress through an AMPK - PPAR5 - dependent *** Aortas of wild - type mice were cultured with high glucose,ER stress inducer tunicamycin,chemical chaperones 4 - phenyl butyric acid(PBA) and taurine - conjugated ursodeoxycholic acid(TUDCA),or AMPK activator *** - month - old non - diabetic db/m and diabetic db/db mice were assigned to have one - month running exercise at 8 m/min for 30 min *** pressure,glucose and insulin tolerance were measured before and after treatment. PPARS wild - type and knockout mice fed on normal chow and high fat diet were subjected to daily exercise *** reactivity of aortas and mesenteric arteries was measured in isometric *** of different proteins were assessed by Western *** oxygen species(ROS) levels in vascular tissues were determined using dihydroethidium(DHE) fluorescence *** High glucose and tunicamycin impaired endothelium - dependent relaxations to acetylcholine,decreased phosphorylation of AMPK,increased ER stress markers such ATF6,phosphorylation of eIF2αand ATF3,and elevated the ROS level in mouse *** effects were reversed by PBA,TUDCA and *** - month exercise significantly improved acetycholine - induced endothelium - dependent relaxations,increased p - AMPK,reduced p - eIF2αand inhibited ROS level in aortas of exercised db/db mice compared to the sedentary mice. Exercise training also improved insulin tolerance and enhanced endothelium - dependent relaxations to insulin in mesenteric *** beneficial effects of ex

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2017年第10期14卷 639-643页

作者： Ahmed Bayoumy Meng-Qi GONG Ka Hou Christien Li Sunny Hei wong William KK Wu Guang-Ping LI George Bazoukis Konstantinos P Letsas wing tak wong Yun-Long XIA Tong LIU Gary Tse Department of Medicine and Therapeutics Faculty of Medicine Chinese University of Hong Kong Hong Kong China Li Ka Shing Institute of Health Sciences Faculty of Medicine Chinese University of Hong Kong Hong Kong China Faculty of Medicine University of Amsterdam The Netherlands Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease Department of Cardiology Tianjin Institute of Cardiology Second Hospitalof Tianjin Medical University Tianjin China Faculty of Medicine Newcastle University United Kingdom Department of Anaesthesia and Intensive Care Faculty of Medicine Chinese University of Hong Kong Hong Kong China Second Department of Cardiology Evangelismos General Hospital of Athens Athens Greece School of Life Sciences Chinese University of Hong Kong Hong Kong China Department of Cardiology First Affiliated Hospital of Dalian Medical University Dalian China

Brugada syndrome （BrS） is primary electrical disorder characterized by ST segment elevation with right bundle branch block morphology in patients with apparent structurally normal hearts, It predisposes affected individuals to ventricular tachycardia/fibrillation （VT/VF） and sudden cardiac death （SCD）.A number of studies have identified risk factors that are associated with a more malignant course of disease. These include male gender, syncope, a spontaneous type 1 ECG pattern, family history of SCD, family history of Brugada syndrome,

关键词： Brugada syndrome Risk stratification Spontaneous type 1 Sudden cardiac death Ventricular arrhythmia

Synthetic brochosomes:Design,synthesis,and applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2024年第2期17卷 734-742页

作者： Lin Wang Jinsol Choi tak-Sing wong Department of Mechanical Engineering The Pennsylvania State UniversityUniversity ParkPA 16802USA Materials Research Institute The Pennsylvania State UniversityUniversity ParkPA 16802USA Department of Biomedical Engineering The Pennsylvania State UniversityUniversity ParkPA 16802USA

Brochosomes,which are nanoscopic buckyball-shaped granules produced by leafhoppers,are one of the most intricate structures discovered in *** functions of brochosomes have been proposed but only a few have been experimentally validated due to the challenge of fabricating their synthetic *** in micro-and nanofabrication have recently led to the emergence of synthetic brochosomes,opening up new possibilities for innovative *** review explores the early discovery of natural brochosomes and their geometrical features,followed by the recent progress in fabricating synthetic brochosomes and their *** on future applications and challenges in the scalable manufacturing of synthetic brochosomes are discussed.

关键词： synthetic brochosomes leafhopper antireflection superhydrophobicity surface-enhanced Raman scattering photocatalyst energy harvesting

Three-Photon Up-conversion from Polymeric Lanthanide (III) Complexes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Three-Photon Up-conversion from Polymeric Lanthanide (III) C...