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Prehabilitation prior to intestinal resection in Crohn’s disease patients:An opinion review

World Journal of Gastroenterology 2022年第22期28卷 2403-2416页

作者： Michiel T J Bak Marit F E Ruiterkamp Oddeke van Ruler Marjo J E Campmans-Kuijpers Bart C Bongers Nico L U van Meeteren C Janneke van der Woude Laurents P S Stassen Annemarie C de vries department of Gastroenterology and Hepatology Erasmus University Medical Center RotterdamRotterdam 3015 GDNetherlands department of Surgery IJsselland HospitalCapelle aan den IJssel 2906 ZCNetherlands department of Surgery Erasmus University Medical Center RotterdamRotterdam 3015 GDNetherlands department of Gastroenterology and Hepatology University Medical Center Groningen and University of GroningenGroningen 9713 GZNetherlands department of Nutrition and Movement Sciences School of Nutrition and Translational Research in MetabolismMaastricht UniversityMaastricht 6200 MDNetherlands department of Epidemiology Care and Public Health Research InstituteMaastricht UniversityMaastricht 6200 MDNetherlands department of Anaesthesiology Erasmus MC University Medical Center RotterdamRotterdam 3015 GDNetherlands department of Surgery Maastricht University Medical CenterMaastricht 6229 HXNetherlands

Patients with Crohn’s disease(CD)are at a considerable risk for intestinal *** 25%of patients with CD will undergo an intestinal resection within 10 years of *** complications after CD surgery have been reported in 20%-47%of the *** general and CD-related risk factors are associated with postoperative complications,and comprise non-modifiable(e.g.,age)and potentially modifiable risk factors(e.g.,malnutrition).Prehabilitation focuses on the preoperative period with strategies designed to optimize modifiable risk factors concerning the physical and mental condition of the individual *** aim of prehabilitation is to enhance postoperative recovery and return to or even improve preoperative functional *** improvement of nutritional status,physical fitness,cessation of smoking,psychological support,and critical revision of preoperative use of CD medication are important *** of the effect on postoperative outcome in CD patients are scarce,and guidelines lack recommendations on tailored *** this opinion review,we review the current evidence on the impact of screening and management of nutritional status,physical fitness,CD medication and laboratory values on the postoperative course following an intestinal resection in CD *** addition,we aim to provide guidance for individualized multimodal prehabilitation in clinical practice concerning these modifiable factors.

关键词： Crohn’s disease Prehabilitation strategies Nutrition Physical fitness Medication Laboratory values

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Effects of sebum properties on skin friction:investigation using a bench test

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Biosurface and Biotribology 2020年第2期6卷 43-47页

作者： Kerlen T.Korbeld Michel Klaassen Rikeen D.Jobanputra Erik Gde vries Marc A.Masen Rijksuniversiteit Groningen Groningen9700 ABThe Netherlands Mechanical Engineering Imperial College LondonLondonSW72AZUK Universiteit Twente EnschedeOverijssel7500 AEThe Netherlands

The hydro lipid film is an emulsion of sweat and sebum that covers the surface of the human skin and affects the tribological properties of the human *** study investigates the effects of the composition of the sebum on the average coefficient of friction.A range of simplified sebums was developed and the friction behaviour was *** realistic sebums showed a strong variation in friction results,indicating that interpersonal differences in frictional behaviour might have their origin in differences in sebum composition.A more detailed investigation employing controlled variations of individual ingredients showed that friction is highly sensitive to the amount of squalene in the *** amount of fatty acids in the sebum also showed some effects,whilst the amount of cholesterol does not appear to be relevant for the friction *** main new outcome from this study is that the composition of sebum has a significant effect on the friction response of skin in ways that are currently not yet fully understood.

关键词： friction behaviour properties

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Metabolic-associated fatty liver disease is associated with low muscle mass and strength in patients with chronic hepatitis B

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World Journal of Hepatology 2022年第8期14卷 1652-1666页

作者： Cecy Maria de Lima Santos Matheus Duarte Brito Pedro Alves Soares Vaz de Castro Thais Pontello de vries Nataly Lopes Viana Marta Paula Pereira Coelho Olívio Brito Malheiro Tatiana Bering Maria Cristina Gonzalez Rosangela Teixeira Rodrigo Dias Cambraia Gifone Aguiar Rocha Luciana Diniz Silva Sciences Applied to Adult Health Care Post-Graduate Programme Faculdade de Medicina Universidade Federal de Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil Outpatient Clinic of Viral Hepatitis Instituto Alfa de GastroenterologiaFaculdade de MedicinaUniversidade Federal de Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil Faculdade de Medicina Universidade Federal de Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil department of Locomotor System Faculdade de MedicinaUniversidade Federal de Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil department of Food and Nutrition Universidade Federal de Mato GrossoCuiabá78060-900Mato GrossoBrazil Postgraduate Program in Health and Behaviour Catholic University of PelotasPelotas 96015-560Rio Grande do SulBrazil Laboratory of Research in Bacteriology Faculdade de MedicinaUniversidade Federal de Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil department of Internal Medicine Universidade Federal de Minas GeraisBelo Horizonte 30130-100Minas GeraisBrazil

BACKGROUND Although the prognostic relevance of sarcopenia has been increasingly recognised in the context of liver disease,there is a paucity of data evaluating body composition in patients with chronic hepatitis B(CHB).Beyond virus-related factors,nutritional and metabolic aspects can be associated with skeletal muscle abnormalities in these patients and should not be *** To evaluate the association between components of sarcopenia and demographic,clinical,lifestyle,nutritional,and biochemical variables in CHB *** Dual-energy X-ray absorptiometry(DXA)was used to assess muscle mass by quantifying appendicular lean mass(ALM)adjusted for body mass index(ALMBMI).Muscle function was evaluated by hand grip strength(HGS)and the timed up and go ***-associated fatty liver disease(MAFLD)was defined according to the criteria proposed by an international expert panel.A body shape index and the International Physical Activity Questionnaire were used to assess central obesity and physical activity level,*** This cross-sectional study included 105 CHB outpatients followed at the tertiary care ambulatory centre(mean age,48.5±12.0 years;58.1%males;76.2%without cirrhosis;23.8%with compensated cirrhosis).The DXA-derived fat mass percentage was inversely correlated with the ALMBMI(r=-0.87)and HGS(r=-0.63).In the multivariable analysis,MAFLD,sedentarism and central obesity were positively and independently associated with low *** and central obesity were independently associated with low *** MAFLD and central obesity were associated with low muscle mass and strength in patients with chronic hepatitis B,independent of the liver disease stage.

关键词： Chronic hepatitis B Appendicular lean mass Muscle strength Metabolic associated fatty liver disease Central obesity Physical performance

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针对女性卫生工作者的暴力——性别权力失衡之冰山一角

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英国医学杂志中文版 2021年第1期24卷 52-56页

作者： Asha S George Frances E McConville Shaheem de vries Gustavo Nigenda Shabnum Sarfraz Michelle McIsaac 杨润丽(译) School of Public Health University of the Western CapeSouth Africa department of Maternal NewbornChild and Adolescent HealthWorld Health OrganizationSwitzerland Emergency Medical Services Western Cape Government HealthSouth Africa National School of Nursing and Obstetrics National Autonomous University of MexicoMexico Ministry of Planning Development and Special InitiativesGovernment of PakistanPakistan Health Workforce department World Health OrganizationSwitzerland 北京师范大学附属实验中学

"处理性别权力关系是确保卫生工作者安全与健康的关键,也是提供优质卫生服务的重要环节。"——阿莎·乔治(Asha George)及同事二十五年前,《北京宣言和行动纲要》宣布妇女具有卫生保健的权利。该纲领指出,女性不仅能够享受医疗服务,还... 详细信息

"处理性别权力关系是确保卫生工作者安全与健康的关键,也是提供优质卫生服务的重要环节。"——阿莎·乔治(Asha George)及同事二十五年前,《北京宣言和行动纲要》宣布妇女具有卫生保健的权利。该纲领指出,女性不仅能够享受医疗服务,还是此项服务的重要提供者。

关键词：卫生工作者权力失衡卫生保健卫生服务北京宣言医疗服务性别权力关系安全与健康

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AES专论:波前合成(待续)

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电声技术 2014年第5期38卷 40-47页

作者： Diemer de vries 陈小平(编译) 荷兰代尔夫特理工大学荷兰代尔夫特理工大学声学实验室海牙皇家音乐学院的音响系中国传媒大学音乐与录音艺术学院北京100024

对WFS技术的原理和理论以及在过去20年的技术发展情况进行了概括总结,并且简要介绍了WFS的实际应用系统。对WFS的原理、发展和应用进行了全面而系统的介绍,该技术未来将在多媒体展示中得到巨大的发展。

关键词：波前合成立体声扬声器

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标准化——多学科领域研究

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中国标准化 2011年第9期 36-41页

作者： Henk J.de vries 荷兰ERASMUS大学鹿特丹管理学院

本文通过一个系统的科学清单与标准化的特性相对照，指出了能够对标准化研究有贡献的学科，并且论证了标准化需要一个多学科的特殊方法来进行研究，其中管理学研究能够把其他学科的研究集成起来。

关键词：标准化多学科管理学

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Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism

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Acta Pharmaceutica Sinica B 2023年第2期13卷 618-631页

作者： Changpei Gan Jing Wang Alejandra Martínez-Chávez Michel Hillebrand Niels de vries Joke Beukers Els Wagenaar Yaogeng Wang Maria C.Lebre Hilde Rosing Sjoerd Klarenbeek Rahmen Bin Ali Colin Pritchard Ivo Huijbers Jos H.Beijnen Alfred H.Schinkel Division of Pharmacology the Netherlands Cancer InstituteAmsterdam 1066 CXthe Netherlands department of Pharmacy&Pharmacology the Netherlands Cancer InstituteAmsterdam 1066 CXthe Netherlands Division of Pharmacoepidemiology and Clinical Pharmacology Utrecht Institute for Pharmaceutical SciencesUtrecht UniversityUtrecht 3584 CSthe Netherlands Experimental Animal Pathology Facility the Netherlands Cancer InstituteAmsterdam 1066 CXthe Netherlands Mouse Clinic for Cancer and Aging(MCCA)Transgenic Facility the Netherlands Cancer InstituteAmsterdam 1066 CXthe Netherlands

The mammalian carboxylesterase 1(Ces1/CES1)family comprises several enzymes that hydrolyze many xenobiotic chemicals and endogenous *** investigate the pharmacological and physiological roles of Ces1/CES1,we generated Ces1 cluster knockout(Ces1^(-/-))mice,and a hepatic human CES1 transgenic model in the Ces1^(-/-)background(TgCES1).Ces1^(-/-)mice displayed profoundly decreased conversion of the anticancer prodrug irinotecan to SN-38 in plasma and ***1 mice exhibited enhanced metabolism of irinotecan to SN-38 in liver and ***1 and hCES1 activity increased irinotecan toxicity,likely by enhancing the formation of pharmacodynamically active ***1^(-/-)mice also showed markedly increased capecitabine plasma exposure,which was moderately decreased in TgCES1 ***1^(-/-)mice were overweight with increased adipose tissue,white adipose tissue inflammation(in males),a higher lipid load in brown adipose tissue,and impaired blood glucose tolerance(in males).These phenotypes were mostly reversed in TgCES1 ***1 mice displayed increased triglyceride secretion from liver to plasma,together with higher triglyceride levels in the male *** results indicate that the carboxylesterase 1 family plays essential roles in drug and lipid metabolism and ***1^(-/-)and TgCES1 mice will provide excellent tools for further study of the in vivo functions of Ces1/CES1 enzymes.

关键词： Ces1/CES1 enzymes Irinotecan Capecitabine Adipose tissue Lipid homeostasis Inflammation Triglyceride mobilization Mouse models

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从更快到更好——恩智浦半导体的新摩尔定律(More-than-Moore)(上)

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电子与电脑 2009年第9期9卷 29-30页

作者： René Penning de vries 恩智浦

多年来摩尔定律（Moore’s Law）推动了产能提升，也带动了半导体产业惊人的发展。这驱动力创造了超高速数字处理器、带宽的提升及容量庞大的内存，使得个人计算机、移动电话以及需要大量数据流量与储存空间的应用装置，生产力获得大幅... 详细信息

多年来摩尔定律（Moore’s Law）推动了产能提升，也带动了半导体产业惊人的发展。这驱动力创造了超高速数字处理器、带宽的提升及容量庞大的内存，使得个人计算机、移动电话以及需要大量数据流量与储存空间的应用装置，生产力获得大幅提升。然而，IC产业的经济及社会发展，正在推动半导体世界的典范转移（paradigm shift）与改变。

关键词：半导体产业摩尔定律数字处理器个人计算机人的发展应用装置储存空间数据流量

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AES专论:波前合成(续三)

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电声技术 2014年第8期38卷 38-44,58页

作者： Diemer de vries 陈小平中国传媒大学音乐与录音艺术学院北京100024

6 目前发展水平及应用在CARROUSO项目完成后,WFS技术引起全世界的关注,被公认为一种不受所谓“最佳听音点”限制的声音重放制式.重放扬声器阵列存在不同的排列方式,但有一点是一致的,那就是分布在听音者所在的水平面上.

关键词： AES 合成波前声音重放扬声器阵列排列方式水平面听音

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AES专论:波前合成(续一)

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电声技术 2014年第6期38卷 28-34,43页

作者： Diemer de vries 陈小平中国传媒大学音乐与录音艺术学院北京100024

（上接2014年38卷5期47页）3．5反射声的重放正如前面已经提到，每个界面反射声都可以看成一个镜像声源的直达声。理论研究表明，镜像声源的密度随时间的平方增大。这意味着，在一个混响时间为1s的房问，相对于直达声，延时在1s以内的... 详细信息

（上接2014年38卷5期47页）3．5反射声的重放正如前面已经提到，每个界面反射声都可以看成一个镜像声源的直达声。理论研究表明，镜像声源的密度随时间的平方增大。这意味着，在一个混响时间为1s的房问，相对于直达声，延时在1s以内的反射声都对听音起一定作用，并且有成千上万个镜像声源共同建立起了混响的“尾部”。

关键词： AES 合成波前混响时间反射声直达声声源镜像

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