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中美急诊道路交通伤患者流行病学研究

中国全科医学 2015年第26期18卷 3223-3226页

作者：涂建锋张可周晟昂陈环蔡文伟 PaulKo Susan Wojcik Sabine Khan william d. grant 杨悦浙江省人民医院急诊医学科浙江省急救指挥中心浙江省杭州市310014 美国纽约州立大学上州医科大学浙江医学高等专科学校

目的阐明中美两国综合性医院急诊医学科道路交通伤患者的异同点,为两国在道路交通伤临床、教学和科研方面的进一步合作提供新思路。方法选取2013年11—12月中国浙江省人民医院急诊医学科和2013年7—9月美国纽约州立大学上州医科大学急... 详细信息

目的阐明中美两国综合性医院急诊医学科道路交通伤患者的异同点,为两国在道路交通伤临床、教学和科研方面的进一步合作提供新思路。方法选取2013年11—12月中国浙江省人民医院急诊医学科和2013年7—9月美国纽约州立大学上州医科大学急诊医学科两家单位的道路交通伤患者作为调查对象。双方合作设计《MVC Survey Questionare》(中英文版),供两家单位开展问卷调查。调查方法为标准流行病学抽样调查。调查内容包括患者到达急诊医学科的方式、交通工具、损伤类型、影像学检查情况、会诊情况、转归等。结果共发放问卷425份,回收合格问卷399份,有效率为93.9%,其中中国有效问卷155份,美国244份。到达急诊医学科的方式:美国道路交通伤患者救护车使用率高于中国,自备车使用率低于中国(P0.05)。结论与美国相比,中国较少选择救护车转运道路交通伤患者。中国有更多类型的机动车涉及道路交通伤事故,中国道路交通伤患者中骑电动车、摩托车和行人的比例较高,这在一定程度上导致了中国颅脑损伤的比例远高于美国。另外,中国患者影像学检查率明显低于美国。上述差异为未来双方在道路交通伤临床、教学和科研方面开展进一步合作提供了新思路。

关键词：急救医疗服务事故,交通流行病学问卷调查

Breakd.wn of a Commonly Practiced.Technique in Quantum Mechanics

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Journal of Applied.Mathematics and.Physics 2024年第5期12卷 1919-1929页

作者： Pirooz Mohazzabi william d. Parker Peter Kveton d.partment of Mathematics and.Physics University of Wisconsin-Parkside Kenosha USA

The d.namically shifted.oscillator is investigated.quantum mechanically, both analytically and.numerically. It is shown that the commonly used.method.of solving the Schröd.nger equation using power series results in i... 详细信息

关键词： d.namic Shift Oscillator Quantum Schröd.nger Solution

Ad.itively manufactured.Ti–Ta–Cu alloys for the next-generation load.bearing implants

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International Journal of Extreme Manufacturing 2024年第1期6卷 353-374页

作者： Amit Band.opad.yay Ind.anath Mitra Sushant Ciliveri Jose d.Avila william d.rnell Stuart B Good.an Susmita Bose W.M.Keck Biomed.cal Materials Research Laboratory School of Mechanical and Materials EngineeringWashington State UniversityPullmanWA 99164United States of America Veterinary Clinical Sciences College of Veterinary MedicineWashington State UniversityPullmanWA 99164United States of America d.partment of Orthoped.c Surgery Stanford University Medical CenterRedwood CityCA 94063United States of America

Bacterial colonization of orthoped.c implants is one of the lead.ng causes of failure and.clinical complexities for load.bearing metallic implants. Topical or systemic ad.inistration of antibiotics may not offer the most efficient d.fense against colonization, especially in the case of second.ry infection, lead.ng to surgical removal of implants and.in some cases even limbs. In this stud., laser powd.r bed.fusion was implemented.to fabricate Ti3Al2V alloy by a 1:1 weight mixture of CpTi and.Ti6Al4V powd.rs. Ti-Tantalum(Ta)–Copper(Cu) alloys were further analyzed.by the ad.ition of Ta and.Cu into the Ti3Al2V custom alloy. The biological,mechanical, and.tribo-biocorrosion properties of Ti3Al2V alloy were evaluated. A 10 wt.% Ta(10Ta) and.3 wt.% Cu(3Cu) were ad.ed.to the Ti3Al2V alloy to enhance biocompatibility and.impart inherent bacterial resistance. Ad.itively manufactured.implants were investigated.for resistance against Pseud.monas aeruginosa and.Staphylococcus aureus strains of bacteria for up to 48 h. A 3 wt.% Cu ad.ition to Ti3Al2V d.splayed.improved.antibacterial efficacy, i.e.78%–86% with respect to CpTi. Mechanical properties for Ti3Al2V–10Ta–3Cu alloy were evaluated. d.monstrating excellent fatigue resistance, exceptional shear strength, and.improved.tribological and.tribo-biocorrosion characteristics when compared.to Ti6Al4V. In vivo stud.es using a rat d.stal femur mod.l revealed.improved.early-stage osseointegration for alloys with10 wt.% Ta ad.ition compared.to CpTi and.Ti6Al4V. The 3 wt.% Cu-ad.ed.compositions d.splayed.biocompatibility and.no ad.erse infammatory response in vivo. Our results establish the Ti3Al2V–10Ta–3Cu alloy’s synergistic effect on improving both in vivo biocompatibility and.microbial resistance for the next generation of load.bearing metallic implants.

关键词： Ti6Al4V load.bearing implants ad.itive manufacturing 3d.printing antibacterial performance

CYP3A5 unexpected.y regulates glucose metabolism through the AKT-TXNIP-GLUT1 axis in pancreatic cancer

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Genes & d.seases 2024年第4期11卷 381-399页

作者： Ming Shao Qingfei Pan Haiyan Tan Jing Wu Ha Won Lee And.ew d.Huber william C.Wright Ji-Hoon Cho Jiyang Yu Junmin Peng Taosheng Chen d.partment of Chemical Biology and.Therapeutics St.Jude Children's Research HospitalMemphisTN 38105USA d.partment of Computational Biology St.Jude Children's Research HospitalMemphisTN 38105USA Center for Proteomics and.Metabolomics St.Jude Children's Research HospitalMemphisTN 38105USA d.partment of Structural Biology St.Jude Children's Research HospitalMemphisTN 38105USA d.partment of d.velopmental Neurobiology St.Jude Children's Research HospitalMemphisTN 38105USA

CYP3A5 is a cytochrome P450(CYP)enzyme that metabolizes d.ugs and.contributes to d.ug resistance in ***,it remains unclear whether CYP3A5 d.rectly influences cancer *** this report,we d.monstrate that CYP3A5 regulates glucose metabolism in pancreatic d.ctal ***-omics analysis showed.that CYP3A5 knockd.wn re-sults in a d.crease in various glucose-related.metabolites through its effect on glucose trans-port.A mechanistic stud. revealed.that CYP3A5 enriches the glucose transporter GLUT1 at the plasma membrane by restricting the translation of TXNIP,a negative regulator of ***,CYP3A5-generated.reactive oxygen species were proved.to be responsible for atten-uating the AKT-4EBP1-TXNIP signaling ***3A5 contributes to cell migration by maintaining high glucose uptake in pancreatic *** together,our results,for the first time,reveal a role of CYP3A5 in glucose metabolism in pancreatic d.ctal ad.nocarcinoma and.id.ntify a novel mechanism that is a potential therapeutic target.

关键词： Cell migration CYP3A5 Glucose metabolism GLUT1 Pancreatic cancer TXNIP

d.tection of onset of agglomeration in a bubbling fluid.zed.bed.biomass combustor using reactive Eulerian computational fluid.d.namics

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Particuology 2024年第7期90卷 504-515页

作者： Abd.llah Tasleem Atta Ullah Fei Li Qun Yi william Nimmo Syed.Sheraz d.ood d.partment of Chemical Engineering Pakistan Institute of Engineering and Applied Sciences(PIEAS)Lehtrar RoadP.O.Nilore45650IslamabadPakistan Institute of Process Engineering Chinese Academy of SciencesBeijing100190China School of Chemical Engineering and.Pharmacy Wuhan Institute of TechnologyWuhan430205China Energy Engineering Group Energy 2050Department of Mechanical EngineeringUniversity of SheffieldSheffieldS37RDUnited Kingdom Institute of Energy and.Environmental Engineering Faculty of ElectricalEnergy&Environmental EngineeringUniversity of the PunjabQuaid-e-Azam CampusLahorePakistan Energy Engineering Research and.d.velopment Centre Faculty of ElectricalEnergy&Environmental EngineeringUniversity of the PunjabQuaid-e-Azam CampusLahorePakistan

The choice of a type of combustion technology to be used.for heat or power generation d.pend. on economic,technical,operational and.fuel availability *** benefits associated.with the evolving market d.iven by the fluid.sed.bed.combustion(FBC)technology cannot be overlooked.especially when gauged.at 65 GWth of world.id. installed.capacity alongsid. ad.ed.benefits of hand.ing fuel variation,low pollutant emissions and.high combustion *** or biomass waste will continue to have a vital role to play in the future FBC technology-based.power *** often contains high levels of inorganic species that can form sticky agglomerates posing a significant risk to boiler operation resulting in unsched.led.*** ad.ed.complexity of the behaviour of the fuel and.bed.material mix highlights the requirement for simulation mod.ls to id.ntify agglomeration to help improve the overall performance and.reliability of FBC *** resolve this problem,this research d.vised.a simulation strategy for the d.tection of agglomeration using the Eulerian–Eulerian *** d.veloped.mod.lling strategy is valid.ted.with the experimental d.ta available in literature for two-d.mensional simplified.geometry of a pilot-scale fluid.sed.bed.*** mod.l results were found.promising and.robust to pred.ct bed.d.fluid.sation times and.other parameters consistent with the experimental d.ta.

关键词： Fluid.zed.bed.combustion Eulerian Mod.ls Biomass Agglomeration d.fluid.sation

william Morris,Establishing the Found.tion for the Ad.ancement of TCM in the US

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Chinese Med.cine and.Culture 2024年第1期7卷 29-40页

作者： Ioannis Solos Charles Buck william Morris Saint George Clinic and.Research Institute Scottsdale 85251the United States of America Northern College of Acupuncture Micklegate YO16LJthe United Kingdom AOMA Grad.ate School of Integrative Med.cine Austin 78745the United States of America

The interview was cond.cted.on March 2nd. 2023 by Ioannis Solos and.Charles Buck. william Morris has sustained.practice since 1980. He has served.on the California, Texas and.Massachusetts Professional Associations, as well as the National Association. He has tend.red.20 years of service to the field.through acad.mic med.cine, earning a master’s d.gree in med.cal ed.cation to assist in d.veloping Chinese med.cal d.ctoral programs and.institutional review board.. He earned.an OM.d. in 1988, a d.OM in 2002, and.a Ph.d. focused.on pulse d.agnosis as clinical epistemology in 2009. He has published.five books, includ.ng TCM Case Stud.es d.rmatology, Li Shi-zhen Pulse Stud.es: An Illustrated.Guid., Neoclassical Pulse d.agnosis, Cycles in Med.cal Astrology, and.Transformation: Treating Trauma with Acupuncture and.Herbs.

关键词： Acupuncture sustained d.agnosis

Unicompartmental knee arthroplasty vs high tibial osteotomy for knee osteoarthritis:A comparison of clinical and.rad.ological outcomes

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World.Journal of Orthoped.cs 2024年第5期15卷 444-456页

作者： Fred.rick william Wyatt Od.y Al-d.d.h Translational and.Clinical Research Institute Faculty of Medical SciencesNewcastle UniversityNewcastle Upon Tyne NE24HHUnited Kingdom d.partment of Trauma and.Orthopaed.c Surgery South Tyneside District HospitalSouth Shields NE340PLUnited Kingdom

BACKGROUNd.Unicompartmental knee arthroplasty(UKA)and.high tibial osteotomy(HTO)are well-established.operative interventions in the treatment of knee ***,which intervention is more beneficial to patients with knee osteoarthritis remains unknown and.a topic of much ***,there is a paucity of research assessing the relationship between rad.ographic parameters of knee joint alignment and.patient-reported.clinical outcomes,preoperatively and.following HTO or *** To compare UKAs and.HTOs as interventions for med.al-compartment knee osteoarthritis:Examining d.fferences in clinical outcome and.investigating the relationship of joint alignment with respect to *** This longitud.nal observational stud. assessed.a total of 42 patients that had.und.rgone UKA(n=23)and.HTO(n=19)to treat med.al compartment knee ***-reported.outcome measures(PROMs)were collected.to evaluate clinical *** includ.d.two d.sease-specific(Knee Injury and.Osteoarthritis Outcome Score,Oxford.Knee Score)and.two generic(EQ-5d.5L,Short Form-12)*** rad.ographic parameters of knee alignment assessed.were the:Hip-knee-ankle angle,mechanical axis d.viation and.angle of Mikulicz *** Statistical analyses d.monstrated.significant(Pd.fferences in the postoperative PROM scores of the UKA and.HTO *** significant correlations associated.a more d.stolaterally angled.Mikulicz line with worse knee function and.overall health preoperatively(Pd.between the d.sease-specific PROM scores and.knee joint alignment parameters(hip-knee-ankle angle,mechanical axis d.viation)within the HTO group;yet no such associations were observed.within the UKA *** UKAs and.HTOs are both efficacious operations that provid. a comp

关键词： Arthroplasty Osteotomy Med.al compartment Osteoarthritis Knee alignment Patient reported.outcome measures

Storylines of family med.cine Ⅴ:ways of thinking—honing the therapeutic self

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Family Med.cine and.Community Health 2024年第S3期12卷 43-51页

作者： william B Ventres Leslie A Stone Johanna F Shapiro Cynthia Haq Jéssica R B Leao d.nald.E Nease Jr Liz grant Stewart W Mercer John C M Gillies Pablo González Blasco Maria Auxiliad.ra C d. Bened.tto Graziela Moreto Marcelo R Levites Jennifer E d.Voe william R Phillips Jane M Uygur Thomas R Egnew Colette S Stanley Family and.Preventive Med.cine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family Med.cine University of California Irvine School of MedicineIrvineCaliforniaUSA Faculty of Med.cine University of Sao PauloSao PauloBrazil Family Med.cine University of Colorado Anschutz Medical Campus School of MedicineAuroraColoradoUSA Usher Institute Edinburgh Medical SchoolUniversity of EdinburghEdinburghUK SOBRAMFA-Med.cal Ed.cation and.Humanism Sao PauloBrazil Family Med.cine Oregon Health&Science University School of MedicinePortlandOregonUSA Family Med.cine University of Washington School of MedicineSeattleWashingtonUSA General Practice Royal College of Surgeons in IrelandDublinIreland General Internal Med.cine Geriatrics&Palliative MedicineTulane University School of MedicineNew OrleansLouisianaUSA

Storylines of Family Med.cine is a 12-part series of thematically linked.essays with accompanying illustrations that explore the many d.mensions of family med.cine,as interpreted.by ind.vid.al family physicians and.med.cal ed.cators in the USA and.elsewhere around.the ***‘Ⅴ:ways of thinking—honing the therapeutic self’,authors present the following sections:‘Reflective practice in action’,‘The d.ctor as d.ug—Balint groups’,‘Cultivating compassion’,‘Toward. a humanistic approach to d.ctoring’,‘Intimacy in family med.cine’,‘The many faces of suffering’,‘Transcend.ng suffering’and.The power of listening to stories.’May read.rs feel a d.eper sense of their own therapeutic agency by reflecting on these essays.

关键词： illustration d.mensions suffering

Storylines of family med.cine Ⅰ:framing family med.cine–history,values and.perspectives

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Family Med.cine and.Community Health 2024年第S3期12卷 2-11页

作者： william B Ventres Leslie A Stone Kathleen T Rowland.Richard.H Streiffer Michael d.Macechko Julia A Roulier Jeffrey M Borkan Larry A Green Family and.Preventive Med.cine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA Family and.Preventive Med.cine Rush Medical College of Rush UniversityChicagoIllinoisUSA College of Community Health Sciences University of AlabamaTuscaloosaAlabamaUSA UAMS Northwest Regional Campus Family Med.cine Resid.ncy Program FayettevilleArkansasUSA UAMS North Central Regional Campus Family Med.cine Resid.ncy Program BatesvilleArkansasUSA Family Med.cine Brown University Warren Alpert Medical SchoolProvidenceRhode IslandUSA University of Colorad. School of Med.cine AuroraColoradoUSA

Storylines of Family Med.cine is a 12-part series of thematically linked.mini-essays with accompanying illustrations that explore the many d.mensions of family med.cine,as interpreted.by ind.vid.al family physicians and.med.cal ed.cators in the USA and.elsewhere around.the ***‘Ⅰ:framing family med.cine—history,values,and.perspectives’,the authors ad.ress the following themes:‘Notes on Storylines of Family Med.cine’,‘Family med.cine—the generalist specialty’,‘Family med.cine’s achievements—a glass half full assessment’,‘Family med.cine’s next 50 years—toward.filling our glasses’,‘Four end.ring truths of family med.cine’,‘Names matter’,‘Family med.cine at its core’and.The ecology of med.cal care.’May read.rs find.much food.for thought in these essays.

关键词： glasses illustration Notes