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Clostridium difficile-associated disease:Adherence with current guidelines at a tertiary medical center

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World Journal of Gastroenterology 2013年第46期19卷 8647-8651页

作者： Bryan F curtin Yousef Zarbalian Mark H Flasar Erik von Rosenvinge Resident in Internal Medicine Department of Medicine University of Maryland School of Medicine Baltimore Division of Gastroenterology and Hepatology Department of Medicine University of Maryland School of Medicine and VA Maryland Health Care System Baltimore

AIM:To assess adherence with the the Society for Healthcare Epidemiology of America(SHEA)/the Infectious Diseases Society of America(IDSA)guidelines for management of Clostridium difficile(***)-associated disease(CDAD)at a tertiary medical ***:All positive *** stool toxin assays in adults between May 2010 and May 2011 at the University of Maryland Medical Center were *** episodes were classified as guideline adherent or nonadherent and these two groups were compared to determine demographic and clinical factors predictive of *** regression analysis was performed to assess the effect of multiple predictors on guideline ***:320 positive *** stool tests were identified in 290 *** by disease severity criteria set forth by the SHEA/IDSA guidelines,42.2%of cases were mild-moderate,48.1%severe,and 9.7%*** adherence with the guidelines was observed in only 43.4%of *** was65.9%for mild-moderate CDAD,which was significantly better than in severe cases(25.3%)or severe-complicated cases(35.5%)(P<0.001).There was no difference in demographics,hospitalization,ICU exposure,recurrence or 30-d mortality between adherent and non-adherent groups.A multivariate model revealed significantly decreased adherence for severe or severecomplicated episodes(OR=0.18,95%CI:0.11-0.30)and recurrent episodes(OR=0.46,95%CI:0.23-0.95).CONCLUSION:Overall adherence with the SHEA/IDSA guidelines for management of CDAD at a tertiary medical center was poor;this was most pronounced in severe,severe-complicated and recurrent *** interventions aimed at improving guideline adherence are warranted.

关键词： Clostridium difficile Metronidazole Vanco-mycin Adherence to the Infectious Diseases Society of America Guidelines Hospital Acquired Infections

Sternal metastasis-the forgotten column and its effect on thoracic spine stability

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World Journal of Orthopedics 2017年第6期8卷 455-460页

作者： Robert Pearse Piggott Mark curtin Sudarshan Munigangaiah Mutaz Jadaan John Patrick McCabe Aiden Devitt Department of Trauma and Orthopaedic Surgery Galway University Hospitalsthe West/North West Hospitals GroupHSE

Sternal metastases are not studied extensively in the literature. There is a paucity of information on their role in metastatic disease. The concept of the fourth column was described by Berg in 1993, and has been proven in case report, clinically and biomechanical studies. The role of the sternum as a support to the thoracic spine is well documented in the trauma patients, but not much is known about its role in cancer patients. This review examines what is known on the role of the fourth column. Following this we have identified two likely scenarios that sternal metastases may impact management:(1) sternal pathological fracture increases the mobility of the semi-rigid thorax with the loss of the biomechanical support of the sternum-rib-thoracic spine complex; and(2) a sternal metastasis increases the risk of fracture, and while being medical treated the thoracic spine should be monitored for acute kyphosis and neurological injury secondarily to the insufficiency of the fourth column.

关键词： Fourth column Sternal fracture Sternal metastasis Sternal-rib-thoracic spine complex Spine stability

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隐性的粒子世界

物理 2017年第6期46卷 390-391页

作者：来小禹徐仁新 David curtin Raman Sundrum 北京大学

至今尚未发现的神奇粒子事件将揭示自然界最深奥的秘密。为何存在物质而非虚空？这一问题既有深度又有广度,似乎超出定量刻画的范畴。而又令人惊讶的是,该问题可在粒子物理框架内描述并至少部分地解答。标准模型（standard model,SM）... 详细信息

至今尚未发现的神奇粒子事件将揭示自然界最深奥的秘密。为何存在物质而非虚空？这一问题既有深度又有广度,似乎超出定量刻画的范畴。而又令人惊讶的是,该问题可在粒子物理框架内描述并至少部分地解答。标准模型（standard model,SM）是描述物质及其相互作用的基本理论。

关键词：定量刻画宇宙学希格斯玻色子早期宇宙子场普朗克质量大型强子对撞机长寿命粒子对撞 interacting

Approximating Nonlinear Relations Between Susceptibility and Magnetic Contents in Rocks Using Neural Networks

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Tsinghua Science and Technology 2010年第3期15卷 281-287页

作者： william W Guo Michael Li Zhengxiang Li Greg Whymark Faculty of Arts Business lnformatics and Education Central Queensland University Rockhampton QLD 4701 Australia The Institute for Geoscience Research (TIGER) Curtin University of Technology Perth WA 6845 Australia

Correlations between magnetic susceptibility and contents of magnetic minerals in rocks are important in interpreting magnetic anomalies in geophysical exploration and understanding magnetic behaviors of rocks in rock magnetism studies. Previous studies were focused on describing such correlations using a sole expression or a set of expressions through statistical analysis. In this paper, we use neural network techniques to approximate the nonlinear relations between susceptibility and magnetite and/or hematite contents in rocks. This is the first time that neural networks are used for such study in rock magnetism and magnetic petrophysics. Three multilayer perceptrons are trained for producing the best possible estimation on susceptibility based on magnetic contents. These trained models are capable of producing accurate mappings between susceptibility and magnetite and/or hematite contents in rocks. This approach opens a new way of quantitative simulation using neural networks in rock magnetism and petrophysical research and applications.

关键词： neural networks nonlinear function approximation rock magnetism magnetic susceptibility magnetic contents

BIFURCATIONS OF A CUBIC SYSTEM PERTURBED BY DEGREE FIVE

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Acta Mathematica Scientia 2009年第1期29卷 11-24页

作者：尚德生张同华 School of Mathematics and Information Science Shandong University of Technology Department of Chemical Engineering Curtin University of Technology

In this article, using multi-parameter perturbation theory and qualitative analysis, the authors studied a kind of cubic system perturbed by degree five and ob-tained the system that can have 17 limit cycles giving th... 详细信息

关键词： Perturbation singular point value homoclinic loop limit cycle

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两种热带土壤对硫酸离子的吸持机制

农业科技译丛（湖南） 1991年第2期20卷 89-94页

作者： curtin,D 周立祥

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面对人类社会可持续发展的能源选择(英文)

燃料化学学报 2005年第4期33卷 399-406页

作者： Dong-ke Zhang Centre for Fuels and Energy Curtin University of Technology GPO Box U1987 Perth WA 6845 Australia

经济增长和人类的可持续发展,需要廉价、可靠和环境友好的能源供给和利用,然而目前使用的主要能源, 包括天然气、石油、煤炭、核能和可再生能源,以及它们的主要利用方式,并不能完全满足这种要求。现有能源系统的变革,以提高效率、消除... 详细信息

经济增长和人类的可持续发展,需要廉价、可靠和环境友好的能源供给和利用,然而目前使用的主要能源, 包括天然气、石油、煤炭、核能和可再生能源,以及它们的主要利用方式,并不能完全满足这种要求。现有能源系统的变革,以提高效率、消除污染物排放、减少单位能量温室气体的释放,是实现可持续发展的第一关键步骤。要真正实现可持续发展,必须在不断研究与发展的基础上,首先进行能源资源和利用技术的创新变革。以可再生资源为能源的燃料电池和氢经济,是满足可持续发展要求的零排放的能源技术中,最恰当的结合。煤炭由于其储量丰富、便宜、安全和使用期长,在这种转型过程中扮演着关键角色。煤气化与燃料电池技术和未来二氧化碳(CO2)的分离与储存技术的结合,可以实现零排放。煤炭利用技术也将提高可再生能源,特别是生物质和废弃物,在可持续能源中的比例和重要性。

关键词：煤气化能源选择氢经济多联供可持续发展

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生理性与病理性近视遗传学和外界因素

国外医学(眼科学分册) 1981年第2期 80-82页

作者： curtin BJ 李志辉

正常眼各屈光介质屈光力联合的结果而造成的近视,一般称之为生理性近视。这些眼的总屈光力(角膜加晶体)与眼轴的相互关系失谐,以致后焦面落于视网膜之前,每个屈光介质屈光力的值都在常态分布曲线范围之内,眼球的解剖和生理功能正常。至... 详细信息

正常眼各屈光介质屈光力联合的结果而造成的近视,一般称之为生理性近视。这些眼的总屈光力(角膜加晶体)与眼轴的相互关系失谐,以致后焦面落于视网膜之前,每个屈光介质屈光力的值都在常态分布曲线范围之内,眼球的解剖和生理功能正常。至于各屈光介质之间相互关系的失谐是属于偶然发生,还是具有遗传性,目前还不明了。病理性近视属于病态,为一独立的疾患,具有若干特点:(1)视功能异常,如视力不能完全矫正、光敏锐度减低、暗适应不良、视野改变和

关键词：近视弧后极部晶体屈光力生理性眼轴长度高度近视眼外界因素后葡萄肿锯齿缘眼压增高屈光介质

微生物采矿与金属回收:有关公司走上了这条漫长而谨慎的道路

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遗传工程 1985年第2期 36-42页

作者： M.E.curtin 胡辛之

大家知道,生物技术已经成为制药业和诊断业的注意中心,而其他一些行业也在调研生物技术在某些更为深奥的领域中的应用潜力。虽然现在还只有美国的一家专业公司在致力于生物技术在采矿和冶金业中的应用——与之相比,专门从事医学或实验... 详细信息

大家知道,生物技术已经成为制药业和诊断业的注意中心,而其他一些行业也在调研生物技术在某些更为深奥的领域中的应用潜力。虽然现在还只有美国的一家专业公司在致力于生物技术在采矿和冶金业中的应用——与之相比,专门从事医学或实验室研究与开发的生物技术公司已有100多家了。不过已有几家大采矿和冶金公司在探索微生物工程和遗传工程的可能用途。

关键词： BC 研究与开发研究与发展废物回收金属回收浸提法财政管理利润微生物采矿冶金业微生物学