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Role of ultrasound imaging in advancing treatment of female patients with pelvic floor mesh complications

1000年

作者： whitney Eleanor Noss.

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World Journal of Obstetrics and Gynecology 2016年第1期5卷 73-77页

作者： William Singh Harpreet Wadhwa whitney Halgrimson Ervin Kocjancic College of Medicine at University of Illinois at Chicago Department of Urology at University of Illinois at Chicago

Application of vaginal mesh for stress urinary incon-tinence has seen widespread use due to its relatively short operative time in combination with its efficacy in treatment. However, vaginal mesh is not without its drawbacks and can lead to mesh erosion or extrusion, infection, dyspareunia, and recurrence of incontinence. Vaginal mesh complications can lead to feelings of hopelessness, isolation, shame, and emotional distress. Furthermore, failure to identify and address these complications in a timely manner can be permanently damaging to patient health. It is vital to be able to identify mesh complications early. Various imaging methodologies exist to visualize vaginal mesh placement and complications, including ultrasound, magnetic resonance imaging （MRI）, and computed tomography （CT）. This invited review paper focuses on the role of ultrasound in mesh visualization, mesh complication identification, and operative planning in the event of subsequent surgical mesh revision. Polypropylene mesh is echogenic on ultrasound, making it a useful tool for visualizing post-operative mesh placement. Transperineal, translabial and endovaginal ultrasound technique use has been described in the pre- and peri-operative setting to identify mesh in complex cases. Effcacy and practicality of CT and MRI use in identifying mesh in these cases is limited.

关键词： Mesh complications Imaging Ultrasound Computed tomography Magnetic resonance imaging Mesh revision Stress urinary incontinence Erosion Extrusion Dyspareunia

Concurrent pulmonary Mycobacterium avium complex (MAC) infection and active Hürthle cell thyroid carcinoma: is there a connection?

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Health 2010年第5期2卷 391-394页

作者： Kara M. Meinke Baehr whitney S. Goldner 不详

We present two cases of pulmonary MAC infection in women with Hürthle cell thyroid carcinoma. Both cases were asymptomatic octogenarian women with active Hürthle cell thyroid carcinoma and prolonged periods of hypothyroidism prior to diagnosis of pulmonary MAC. Mycobacterium avium complex has never been reported in association with any type of thyroid cancer, specifically Hürthle cell carcinoma. A review of the literature and possible associations between the two are discussed in this article.

关键词： Hürthle Cell Thyroid Cancer Hypothyroidism Mycobacterium Avium Complex Cellular Immunity

Conducting clinical research in community mental health settings: Opportunities and challenges

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世界精神病学杂志 2014年第3期4卷 49-55页

作者： Oleg V Tcheremissine whitney E Rossman Manuel A Castro Dineen R Gardner Department of Psychiatry Carolinas Health Care System-Behavioral Health Center Charlotte NC 28203 United States

Tremendous progress has been made in the past decade surrounding the underlying mechanisms and treatment of neuropsychiatric disease. Technological advancements and a broadened research paradigm have contributed to the understanding of the neurochemistry, brain function and brain circuitry involved in neuropsychiatric disorders. The predominant area of unmet medical need in the United States is major psychiatric disorders, and major depressive disorder is the leading cause of disability for ages 15-44. Total spending on research and development by the pharmaceutical industry has grown exponentially during the past decade, but fewer new molecular entities(NME) for the treatment of major psychiatric disorders have received regulatory approvals compared to other therapeutic areas. Though significant expansion has occurred during the "decade of the brain", the translation of clinical trials outcomes into the community mental health setting is deficient. Randomized controlled trials(RCTs) have been the standard approach to clinical evaluation of the safety and efficacy of NMEs for the past 60 years; however, there are significant barriers and skepticism in the implementation of evidence-based outcomes into clinical practice. Recruitment of patients, shortages of experiencedclinical researchers, regulatory requirements and later translation of outcomes into clinical practice are ever growing problems faced by investigators. The community mental health setting presents particular barriers in the replication of therapeutic outcomes from RCTs. The diagnostic complexity of major psychiatric diseases and the highly selective patient populations involved in clinical trials lend to the gap in translation from the "bench to the bedside". The community mental health setting lends to a diverse patient population with numerous co-morbidities and environmental factors that are unaccounted in the average RCT. While we acknowledge the enormous complexity in developing novel and innovat

关键词： Community mental health Clinical trials in psychiatry Study population

Dimension Reduction for Detecting a Difference in Two High-Dimensional Mean Vectors

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Open Journal of Statistics 2021年第1期11卷 243-257页

作者： whitney V. Worley Dean M. Young Phil D. Young Department of Mathematics University of Central Arkansas Conway AR USA Department of Statistical Science Baylor University Waco TX USA Department of Information Systems and Business Analytics Baylor University Waco TX USA

We consider the efficacy of a proposed linear-dimension-reduction method to potentially increase the powers of five hypothesis tests for the difference of two high-dimensional multivariate-normal population-mean vectors with the assumption of homoscedastic covariance matrices. We use Monte Carlo simulations to contrast the empirical powers of the five high-dimensional tests by using both the original data and dimension-reduced data. From the Monte Carlo simulations, we conclude that a test by Thulin [1], when performed with post-dimension-reduced data, yielded the best omnibus power for detecting a difference between two high-dimensional population-mean vectors. We also illustrate the utility of our dimension-reduction method real data consisting of genetic sequences of two groups of patients with Crohn’s disease and ulcerative colitis.

关键词： Homoscedastic Covariance Matrices Test Power Monte Carlo Simulation Moore-Penrose Inverse Singular Value Decomposition

Operative Time as a Measure of Quality in Pancreaticoduodenectomy: Is Faster Better? A Retrospective Review Using the ACS NSQIP Database

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Surgical Science 2015年第9期6卷 418-426页

作者： Gwendolyn M. Garnett Lynne Wilkens whitney Limm Linda L. Wong Department of Surgery John A. Burns School of Medicine University of Hawaii Honolulu USA Department of Surgery Queens Medical Center Honolulu USA

Objective: To determine if pancreaticoduodenectomy operative time can provide insight into surgeon performance and thus be considered for use as a quality indicator. Background: Case volume is the traditional quality metric for complex pancreatic surgery, with studies showing better outcomes for high-volume providers. However, there are surgeons performing fewer cases with good quality who are overlooked for referrals directed to high-volume “centers of excellence”. Additional quality metrics are needed. Methods: The ACS NSQIP database (2005-2011) was used to identify 4805 pancreaticoduodenectomy patients. Cases were divided at the mean operative time (ORtime) into those ≤373 (n = 2638, 54.9%) vs ≥373 minutes in duration. Complications and outcome measures were compared and predictors of 30-day mortality were assessed. Results: Age ≤ 65 years, male sex, prior chemotherapy, prior radiation, disseminated cancer, diabetes, recent MI, no prior TIA, lower bilirubin and platelet count, and higher prothrombin time were associated with ORtime > 373 minutes. Patients with ORtime > 373 minutes demonstrated more intra-abdominal and superficial infections, wound dehiscence, bleeding requiring transfusion, need for reintubation, septic shock, and returns to OR. ORtime > 373 minutes was associated with longer hospital stay and increased 30-day mortality. ORtime > 373 minutes was a significant and independent predictor in a stepwise model of 30-day mortality. Conclusions: Shorter pancreaticoduodenectomy operative time is associated with fewer complications, shorter hospital stays and lower 30-day mortality after adjusting for patient factors. This may imply that shorter operative time is associated with superior surgical outcome. Operative time may provide insight into surgeon performance and be considered for use as a quality metric.

关键词： Pancreaticoduodenectomy Operative Time

Nutrition: Concepts and Controversies, 10th Edition 10th ed.

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2006年

作者： Frances Sienkiewicz Sizer Frances Sizer Webb Eleanor Noss whitney

Includes index and bibliographical references.

ISBN: (纸本)9780534406721

Includes index and bibliographical references.

关键词： Food.

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社会资本的力量

经理人 2006年第7期 66-68页

作者： whitney MacMillan

嘉吉公司退休CEO强调了在公司内部构建社会资本的重要价值。

关键词：社会资本力量嘉吉公司实践方案 CEO 内部

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来看看哪个国家最宜居?

疯狂英语（新读写） 2018年第3期 56-58页

作者： whitney Houston

Austria 奥地利 Let＇s start with the home of the world＇s most liveable city,Vienna,according to Mercer＇s Quality of Living index,which takes into account a number of factors,including economic and political *** Aust... 详细信息

关键词：宜居 home most spot 奥地利 has top

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视觉性与图画性(Ⅱ)

文化艺术研究 2013年第4期6卷 114-120页

作者： whitney Davis 彭发胜加州大学伯克利分校合肥工业大学外国语学院合肥230009

视觉性是视觉体验的象征形式。视觉性与图画性尽管总是可以相互转化,但无论在任何点上都不完全等同。事实上,在它们进行意义垒叠的每一时刻,视觉性和图画性必须相互分离。图画不能完全表达视觉性本质的"象征价值",正如视觉性不能完全容... 详细信息

视觉性是视觉体验的象征形式。视觉性与图画性尽管总是可以相互转化,但无论在任何点上都不完全等同。事实上,在它们进行意义垒叠的每一时刻,视觉性和图画性必须相互分离。图画不能完全表达视觉性本质的"象征价值",正如视觉性不能完全容纳图画本质的"形式价值"。这种根本的分离造成各种分裂状况,由此激发视觉想象和图画构造,形成了从形式到象征,从图像到"话语",从感知到理智,或者其反向循环的真正机制。

关键词：视觉性图画性垒叠