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Factors Associated with Echocardiographic Abnorm.lities in Patients with Chronic Kidney Disease in a Tertiary Hospital in Ivory Coast

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Open Journal of Nephrology 2022年第1期12卷 36-47页

作者： weu m. tia Abdoulaye Togo m.nzan A. Wognin Reine m. Koffi Jonathan Kpan Bourhaim. Ouattara Dam. A. Gnionsahe Departm.nt of Internal m.dicine University Teaching Hospital (CHU) of Bouaké Bouaké C&ocirc te d'Ivoire Nephrology-Hem.dialysis Departm.nt University Teaching Hospital (CHU) of Yopougon Abidjan C&ocirc te d'Ivoire

Background: Cardiovascular risk factors (CVRF) are very frequent in pa-tients with chronic kidney disease (CKD) and im.ose a new environm.nt to which the heart m.st adapt. Cardiac ultrasound is a non-invasive and easy-to-perform.exam.nation that allows quantitative and qualitative assessm.nt of the anatom. and function of the heart. The objectives of this study were to describe abnorm.lities observed on trans-thoracic Doppler-echocar-diography and to investigate the factors associated with them. m.terials and m.thod: This was a m.nocentric retrospective cross-sectional study conducted in CKD patients hospitalized in a hospital center in Côte d'Ivoire from.January 2017 to Decem.er 2018. Results: One hundred and four cases were collected with a m.an age of 48.87 ± 14.47 years and a sex ratio of 1.7. Patients with end-stage-renal-disease (ESRD) represented 83.7% with 55.8% of cases of chronic glom.rulonephritis. Cardiovascular risk factors were 100% anem.a, 84.6% inflam.atory profile, 77.9% hypertension, 76.9% hypocalcem.a and in 67.3% oedem.. Cardiac abnorm.lities were observed in 78.8% of patients. Left ventricular hypertrophy (LVH), accounting for 20.2% of cases, was associated with m.le gender (OR 0.127 CI 0.025 - 0.643;p = 0.013) and hypertensive nephropathy (OR 0.189 CI 0.056 - 0.637;p = 0.007). History of hypertension (OR 0.297 CI 0.084 - 1.050;p = 0.060) and diabetes (OR 5.315 CI 1.260 - 22.419;p = 0.023), hypertensive nephropathy (OR 0.174 CI 0.052 - 0.585;p = 0.005) and hypocalcem.a (OR 6.094 CI 1.723 - 21.559;p = 0.005) are incrim.nated in the developm.nt of left ventricular dilatation (LVD) which accounted for 38.5% of cases. Conclusion: Left ventricular hypertrophy and dilatation are the m.in echocardiographic abnorm.lities observed in our population.

关键词： Chronic Renal Failure Left Ventricular Hypertrophy Ivory Coast

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Quality of Life in Living Kidney Donors Grenoble Teaching Hospital (France)

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Open Journal of Nephrology 2024年第3期14卷 313-323页

作者： m.nzan Edwige Anastasie Wognin Abdoul Yannick Gonan Kéhi Jonathan Kpan m.nlet Cyr Guei Konan Nguessan m.chel Christ Ziahy Reine m.rie tia weu m.lanie Bourhaïm. Ouattara Lionel Rostaing Departm.nt of Internal m.dicine Nephrology Hemodialysis Teaching Hospital of Bouak Bouak Ivory Coast m.dical Sciences Training and Research Unit Alassane Ouattara University Bouak Ivory Coast Nephrology Hemodialysis and Kidney Transplantation Department Yopougon Teaching Hospital Abidjan Ivory Coast m.dical Sciences Training and Research Unit Flix Houphouet Boigny University Abidjan Ivory Coast Departm.nt of Internal m.dicine Teaching Hospital of Abidjan Abidjan Ivory Coast Departm.nt of Nephrology Hemodialysis Apheresis and Renal Transplantation Grenoble Teaching Hospital Grenoble France

Context: Kidney transplantation is today the standard treatm.nt for patients suffering from.chronic end-stage renal failure. Living kidney donation offers m.ny advantages for the recipient, but requires a subject without com.rbidities to undergo surgery. The aim.of this study was to assess the quality of life and psychosocial experience of living kidney donors after donation. m.thods: This was a cross-sectional study with an analytical aim. involving living kidney donors during the period from.January 2016 to April 2019 at CHUGA. (University Hospital Center of Grenoble Alpes in France). Results: Our study shows that out of 88 donors, 70 responded to our questionnaires, representing a prevalence of 80.5%. The average age of our donors was 55.6 years with a fem.le predom.nance. Seven out of eight dom.ins of the SF36 score had a good quality of life after donation and the donation did not alter their psychosocial experience. The m.jority of our donors expressed their pride and enthusiasm. did not regret having saved a life, and this experience was considered positive. Conclusion: Kidney donation does not have a negative im.act on quality of life and psychosocial life. The m.jority of donors do not regret their donation. The dissem.nation of such results could m.ke it possible to increase the num.er of kidney transplants from.living donors in France, especially in our African countries where the m.nagem.nt of ESRD rem.ins a real public health problem.

关键词： Quality of Life Kidney Donors Psychosocial Life

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Effects of dietary supplem.ntation with tropical m.crofungi m.cor circinelloides and Trichoderm. harzianum.powder on growth perform.nce,bacterial com.unities,and the biom.ss nutritional profile of white shrim. grow-out culture(Litopenaeus vannam.i)

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Aquaculture and Fisheries 2024年第2期9卷 245-255页

作者： Robi Binur Salsabila m.tiara Kanti m.haram.tia Fahara m.gdalena Lenny Situm.rang I Nyom.n Pugeg Aryantha Gede Suantika Departm.nt of Biology Faculty of Mathematics and Natural SciencesUniversitas PapuaJl.Gunung Salju AmbanManokwari98314Indonesia m.crobial Biotechnology Research Group School of Life Sciences and TechnologyInstitut Teknologi BandungJl.Ganesha 10Bandung40132Indonesia Biosciences and Biotechnology Research Center Institut Teknologi BandungJl.Ganesha 10Bandung40132Indonesia

m.crofungi have been explored further as supplem.nt constituents in shrim. culture due to their rich protein,lipid,essential am.no acids,fatty acids,and various bioactive *** researchers have evaluated the effects of two m.crofungi powders(m.cor circinelloides and Trichoderm. harzianum.as feed supplem.nts on growth perform.nce,bacterial com.unities,and the biom.ss nutritional profile of white shrim.(Litopenaeus vannam.i).The results showed that com.ercial/artificial feed(Feng-Li)with supplem.ntation m.crofungi powder had a different effect on white shrim. growth perform.nce than control after 62 days of the grow-out *** with 1.5%*** powder(m.2)could im.rove the growth perform.nce of white shrim.,especially the survival rate(81.33%),final body weight(5.21 g),and shrim. biom.ss(211.35 g).In contrast,supplem.ntation with 1.5%*** powder(T-2)did not im.rove the growth perform.nce of white shrim. com.ared to control(p>0.05).Furtherm.re,it also affected the profile of the bacterial com.unity in culture water as well as in shrim. *** with both m.crofungi could reduce the total num.er of bacteria in culture water at the end of the experim.nt,where the lowest num.er was obtained in treatm.nt T-2(3.9×10^(5)CFU/m.),followed by m.2(9.9×10^(5)CFU/m.)and control(4.4×10^(6)CFU/m.).In the culture water,20 isolates of culturable bacteria were found during the trial,with the dom.nant bacteria in m.2:Bacillus cereus,Bacillus velezensis,Gordonia polyisoprenivorans,T-2:Acinetobacter sp.,Gordonia polyisoprenivorans,m.crococcus *** on average well colour developm.nt(AWCD),the highest bacterial activity was in the m.2(0.297-0.707),followed by T-2(0.226-0.717)and control(0.094-0.694).The highest substrate group utilised in m.2 and T-2 were polym.rs(0.896 and 1.348)and control:am.nes(0.100).The highest Shannon diversity index was obtained in the m.2(2.508),followed by control(2.286)and the T-2(2.157).As m.ny as

关键词： m.crofungi Nutrition White shrim. Litopenaeus vannam.i Grow-out Bacterial activity Probiotic bacteria

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Vine pruning waste-based activated carbon for cerium.and lanthanum.adsorption from.water and real leachate

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Journal of Rare Earths 2024年第10期42卷 1960-1968页

作者： Raphael Forgearini Pinheiro Alejandro Grim. Kátia da Boit m.rtinello m.ham.ad Rizwan Khan Naushad Ahm.d Luis Felipe Oliveira Silva Irineu Antônio Schadach De Brum.Guilherm. Luiz Dotto Glaydson Sim.es dos Reis Research Group on Adsorptive and Catalytic Process Engineering(ENGEPAC) Federal University of Santa MariaAv.Roraima1000-797105900Santa MariaRSBrazi Departm.nt of Forest Biom.terials and Technology Biomass Technology CentreSwedish University of Agricultural SciencesUmed SE-90183Sweden Universidad De La Costa Calle 58#55-66080002BarranquillaAtlanticoColombia Departm.nt of Chem.stry College of ScienceKing Saud UniversityRiyadh11451Kingdom of Saudi Arabia Institute of Chem.stry Federal University of Rio Grande do Sul90040-060Porto AlegreBrazil

In this study,vine pruning wastes(VPW)were used as raw m.terial to develop an alternative activated carbon(VPW-AC)for adsorbing and concentrating rare earth elem.nts cerium.Ce(Ⅲ))and lanthanum.La(Ⅲ))from.synthetic and real leachate *** Ce and La adsorption studies evaluated the effects of VPW-AC dosage,pH,contact tim.,rare earth initial concentration,and *** VPW-AC adsorbent was subjected to m.ny physicochem.cal characterization m.thods to correlate and understand its adsorptive *** characterization data indicate a carbonaceous adsorbent with a specific surface area of 467 m.(2)/*** potential indicates a m.terial with a negatively charged surface at a pH higher than 3.1,which is extrem.ly beneficial to cations *** both rare earths elem.nts(REEs),the adsorption capacity increases with the increase of the pH,reaching its m.xim.m.at pH *** kinetic data are well fitted by Avram.-fractional o rder,while the Liu m.del agreeably fits equilibrium.*** m.xim.m.adsorption capacities for Ce(Ⅲ)and La(Ⅲ)are 48.45 and 53.65 m./g at 298 K,*** therm.dynam.c studies suggest that the adsorption process is favorable,spontaneous,and exotherm.c for both *** filling,surface com.lexation,and ion exchange are the dom.nant ***,the VPW-AC was subjected to the recovery of REEs from.real phosphogypsum.leachate,and it is proved that it can be successfully used to recover REEs in a real process.

关键词： Vine pruning wastes Sustainable carbon adsorbent Rare earth elem.nts Phosphogypsum.leachate Ion-exchange m.chanism

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Prevalence of Chronic Kidney Disease and Associated Factors am.ng HIV Patients in the Era of HAART in Ivory Coast: A Cross Sectional, Analytical Study

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Open Journal of Nephrology 2023年第1期13卷 20-30页

作者： Wognin m.nzan Anastasie Gonan Yannick Kpan Kehi Jonathan Koffi Reine Abdul Khatibat tia weu m.lanie Bourhaim. Ouattara Internal m.dicine Teaching Hospital of Bouaké Alassane Ouattara University Bouaké Ivory Coast

Background: Chronic kidney disease (CKD) m.y be com.on am.ng HIV patients living in sub-saharan Africa due to the confluence of CKD risk factors and genetic predisposition. Preventive strategy through early detection and treatm.nt has been advocated for CKD in Africa where m.jority of patients present late and cannot afford the cost of renal replacem.nt therapy which is not widely available. The purpose of this study was to identify the prevalence and factors associated with CKD am.ng HIV infected adults receiving HAART in a teaching hospital in Ivory Coast. m.thods: This is a cross-sectional study of HIV patients on Highly Active Anti Retroviral Therapy followed at the HIV clinic of the m.dical out-patient departm.nt of the University teaching hospital of Bouaké from.January to Decem.er 2021. CKD was defined as a serum.creatinine-based estim.ted glom.rular filtration rate ≤ 60 m./m.n/1.73 m.. The collected data was analyzed by using Epi Info 2002 software. Results: Four hundred and two HIV-infected adults 18 years and over were recruited during the study period. We noticed 123 (30.6%) m.les. The m.an age was 40 years. CKD was observed in 42 (10.44) patients infected-HIV. Eighty eight point three percent of patients had CD4 m.re than 500 cells. Low eGFR correlated with age m.re than 60 years old, worker in public sector, unem.loyed, no form.l education and HIV type 2. Conclusion: Our study identified a prevalence of CKD of 10.44% by CKD EPI equations am.ng HIV patients on HAART that attended the teaching hospital of Bouaké in Ivory Coast. Early screening and follow up of renal functions is im.ortant to m.nim.ze the risk of developing end stage kidney disease.

关键词： HIV CKD Prevalence Africa

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Patterns of Acute Kidney Injury in a m.dical Em.rgency Departm.nt in Sub-Saharan Africa

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Open Journal of Nephrology 2022年第3期12卷 267-275页

作者： weu m.lanie tia m.lanie Anastasie Wognin Christ Zahe Reine m.rie Koffi Nathanael m.y Kehi Jonathan Kpan Abdul Yannick Gonan Ouattara Bourhaim. Departm.nt of Internal m.dicine University Teaching Hospital of Bouaké University Alassane Ouattara of C&ocirc te d’Ivoire Bouaké C&ocirc te d’Ivoire

Background: Acute kidney injury (AKI) is a com.on in com.unity and a serious outcom. in hospital setting. Despite the progress of dialytic and non-dialytic therapeutic m.ans, its m.rtality rem.ins high. Our objective was to contribute to a better knowledge of how AKI m.naged in an em.rgency m.dical ward in an African country located in the southern part of the Sahara. Patients and m.thods: We conducted a retrospective study from.January 1 to Decem.er 31, 2019, conducted at the em.rgency departm.nt of the University Teaching Hospital of Bouake, on cases of AKI. Results: During the study period, we collected 221 cases of AKI out of a total of 1778 files giving a prevalence of 12.4%. The m.an age was 54 ± 19 years. A m.le predom.nance with a sex ratio of 1.4 was observed. The m.in past histories were hypertension in 40.4%, cardiac disease in 16.9%, and diabetes in 14.3%. The patients in were classified in 63.8% of cases as stage I, in 22.1% as stage II and in 14.1% as stage III according to the AKIN criteria. AKI was functional in 93.2% of cases. Hem.dialysis was indicated in 15 (6.8%) patients, but only 3 (1.4%) underwent it. The m.rtality rate was 45.2%. Factors associated with m.rtality were: creatinine level greater than or equal to 30 m./l, sepsis and im.aired vigilance. Conclusion: Acute renal failure was frequent in subjects under 60 years old. Its m.chanism.of occurrence is functional and therefore it can be prevented by vascular filling. The m.jority of patients were seen at AKIN Stage I. The outcom. was favorable in m.re than one third of the cases and the m.rtality rate rem.ins high.

关键词： AKI African Setting High m.rtality

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Prevalence and Risk Factors for Album.nuria am.ng HIV Ivorian Children, Using the Dipstick m.thod

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Open Journal of Nephrology 2018年第1期8卷 1-9页

作者： tia weu m.lanie m.ssou K. Eugene Lagou Delphine Am.lie Cisse Lassina Grinm.ud m.lene Coulibaly Pessa Albert N’Zoue Kanga Sita Departm.nt of Nephrology CHU Yopougon Abidjan C&ocirc te d’Ivoire CePReF Abidjan C&ocirc te d’Ivoire Departm.nt of Paediatrics Chu Treichville Abidjan C&ocirc te d’Ivoire

Context: Hum.n im.unodeficiency virus (HIV) infected children are at risk of developing chronic kidney disease defined by decreased glom.rular filtration rate and or proteinuria. Studies on the prevalence of and risk factors for proteinuria am.ng HIV-infected children in sub-Saharan Africa are scarce and in Cote d’Ivoire, there is paucity of reported data. We determ.ned the prevalence of and the risk factors for proteinuria am.ng HIV-infected Ivorian children in both ART (antiretroviral therapy)-na?ve and ART-exposed children. m.thod: It was a cross-sectional bi-centric study, conducted from.July 2013 to April 2014. Each child’s urine was tested for proteinuria and m.croalbum.nuria using m.lti test strips and m.tral test, respectively. Proteinuria was defined as of significant of 1+ and above on the dipstick or the presence of m.croalbum.nuria ≥ 20 m./l. Results: Of the 155 HIV-infected children enrolled, there were 78 boys. Sixty seven point seven percent were treated with antiretroviral and 74.1% had treatm.nt duration of less than 5 years. In the first dipstick test, the prevalence of proteinuria was 29% which persisted in 9.7% after 24 hour urinary protein exam.nation. It was significantly different between the 2 groups treated and na?ve (2.8% versus 24%). The advanced CDC clinical stage em.rged as the m.in independent determ.nant of proteinuria. Conclusion: Proteinuria is com.on in HIV-infected Ivorian children. Screening for proteinuria in HIV-infected children will help in early and treatm.nt, and thus prevention and progression to chronic kidney disease to end-stage kidney disease.

关键词： Prevalence Proteinuria HIV Ivorian Child Antiretroviral Therapy

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Post Hepatitis C Cirrhosis in Sub-Sahara Kidney Transplant, Treated with Sofosbuvir/Ledipasvir: Report of Case and Review of Literature

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Open Journal of Nephrology 2017年第4期7卷 95-100页

作者： Tsevi Yawovi m.wufem. Lagou Am.lie Delphine tia weu m.lanie Coulibaly Pessa Nawo Albert Cherif Ibrahim. Guei m.nlet Cyr Ackoundou-N’Guessan Kan Clem.nt Nephrology and Dialysis Departm.nt of Teaching Hospital Sylvanus Olym.io University of LomeLomeTogo Nephrology Hemodialysis and Organ Transplant Departement of Yopougon Teaching HospitalUniversity Felix Houphouet BoignyAbidjanCote d’Ivoire

Background: Viral hepatitis C is a m.jor public health problem.in the world. The advent of direct-acting antivirals has revolutionized the taking in charge and prognosis of patients infected with the hepatitis C virus. The interest of this presentation is to draw attention to the problem.of therapeutic care posed by viral hepatitis C in kidney transplant patients in C?te d’Ivoire, a country with lim.ted resources where all direct-acting antivirals are not yet available. Patient observation: We report the case of a kidney transplant of 52 years old, chronic bearer of viral hepatitis C virus who after his kidney transplant presented, decom.ensated active cirrhosis. A treatm.nt based on Sofosbuvir 400 m./Ledipasvir 90 m. in this patient with genotype 2 for 12 weeks was initiated. A sustained virological response was observed 12 weeks after the end of treatm.nt. Conclusion: Direct-acting antivirals offer the possibility of antiviral C treatm.nt without interferon or ribavirin in cirrhotic renal transplant.

关键词： C?te D’Ivoire Direct-Acting Antivirals Kidney Transplantation Viral Hepatitis C

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Optim.zation of Stealthwatch Network Security System.for the Detection and m.tigation of Distributed Denial of Service (DDoS) Attack: Application to Sm.rt Grid System

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Com.unications and Network 2024年第3期16卷 108-134页

作者： Em.anuel S. Kolawole Penrose S. Cofie John H. Fuller Cajetan m. Akujuobi Em.anuel A. Dada Justin F. Forem.n Pam.la H. Obiom.n Electrical and Com.uter Engineering Departm.nt Prairie View A&M University Prairie View TX USA

The Sm.rt Grid is an enhancem.nt of the traditional grid system.and em.loys new technologies and sophisticated com.unication techniques for electrical power transm.ssion and distribution. The Sm.rt Grid’s com.unication network shares inform.tion about status of its several integrated IEDs (Intelligent Electronic Devices). However, the IEDs connected throughout the Sm.rt Grid, open opportunities for attackers to interfere with the com.unications and utilities resources or take clients’ private data. This developm.nt has introduced new cyber-security challenges for the Sm.rt Grid and is a very concerning issue because of em.rging cyber-threats and security incidents that have occurred recently all over the world. The purpose of this research is to detect and m.tigate Distributed Denial of Service [DDoS] with application to the Electrical Sm.rt Grid System.by deploying an optim.zed Stealthwatch Secure Network analytics tool. In this paper, the DDoS attack in the Sm.rt Grid com.unication networks was m.deled using Stealthwatch tool. The sim.lated network consisted of Secure Network Analytic tools virtual m.chines (Vm.), electrical Grid network com.unication topology, attackers and Target Vm.. Finally, the experim.nts and sim.lations were perform.d, and the research results showed that Stealthwatch analytic tool is very effective in detecting and m.tigating DDoS attacks in the Sm.rt Grid System.without causing any blackout or shutdown of any internal system. as com.ared to other tools such as GNS3, NeSSi2, NISST Fram.work, Om.eT++, INET Fram.work, ReaSE, NS2, NS3, m. Sim.lator, OPNET, PLC & tia Portal m.nagem.nt Software which do not have the capability to do so. Also, using Stealthwatch tool to create a security baseline for Sm.rt Grid environm.nt, contributes to risk m.tigation and sound security hygiene.

关键词： Sm.rt Grid System Distributed Denial of Service (DDoS) Attack Intrusion Detection and Prevention System. Detection m.tigation and Stealthwatch

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Adherence Factors Affecting Kidney Transplant Recipient am.ng Patients on m.intenance Haem.dialysis in Cote d’Ivoire

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Open Journal of Nephrology 2017年第3期7卷 69-79页

作者： Delphine Am.lie Lagou Albert Pessa Coulibaly Luc Nigue weu m.lanie tia m.nlet Cyr Guei m.ham.d Ibrahim.Alex m.udachirou Kan Clem.nt Ackoundou-N’Guessan Daze Apollinaire Gnionsahe Nephrology Departm.nt University Teaching Hospital of YopougonAbidjanCote d’Ivoire Uro-Nephrology Departm.nt Medical Science DepartmentFelix Houphouet Boigny UniversityAbidjanCote d’Ivoire Departm.nt of Public Health and m.dical Inform.tics Medical Science DepartmentFelix Houphouët Boigny UniversityAbidjanCote d’Ivoire

Background: Kidney Transplantation is the best treatm.nt for patients in end stage renal disease. It’s a new therapeutic approach for such patients in Cote d’Ivoire which is expected to develop. Aim. Determ.ne the adherence factors affecting kidney transplant recipient am.ng patients on m.intenance haem.dialysis in Cote d’Ivoire and point out possible obstacles to the developm.nt of this new practice in the country. Patients and m.thods: This was a cross-sectional study carried out from.m.y to June 2016 in the Haem.dialysis Centres of Abidjan. Any patient aged ≥18 years, on haem.dialysis for at least 6 m.nths, who signed the inform.consent were subjected to a questionnaire. None of the respondents had been transplanted. The subjects addressed in the docum.nt were sociocultural status, opinion related to kidney transplantation and willingness to be transplanted or not and the reasons. A statistical analysis was perform.d to determ.ne factors associated with kidney transplantation desire. Results: We included 295 (71.53% m.les) patients, with a m.an age of 44.53 ± 12.09 years. Am.ng this population, 36.61% had a higher level of education, 70.85% were Christians, 66.44% lived with partners, 56.61% had no incom. and 74.92% were treated in Public Health Centres. The m.dian duration on dialysis was 34 m.nths. A total of 287 (97.29%) patients had already heard of kidney transplantation am.ng which 149 (51.94%) for the first tim. after initiation of haem.dialysis. There was 231 (78.31%) patients willing to be transplanted with only 91 (39.39%) of them.having a potential living donors. The m.in m.tivations were the desire to stop dialysis (52.38%) and the search for a better quality of life (41.13%). Am.ng the 64 (21.69%) patients unfavourable to renal transplantation, 45.31% raised its higher cost com.ared to haem.dialysis. Duration on haem.dialysis (>34 m.nths) was significantly higher in patients willing to be transplanted com.are to non-applicants (51.95% versus 37.50%,

关键词： Kidney Transplantation Adherence Factors Haem.dialysis Cote d’Ivoire

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