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Is Peer Victimization Associated with Higher Online Trolling among Adolescents?The Mediation of Hostile Attribution Bias and the Moderation of Trait Mindfulness

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International Journal of Mental Health Promotion 2024年第8期26卷 623-632页

作者： Yuedong Qiu Qi Sun Jie Zhou Ni Jiang wenyu zeng Biyun Wu Fang Li School of Psychology Sichuan Normal UniversityChengdu610066China Center of Adolescent Growth Services Sichuan Dazhu Middle SchoolDazhou635100China Center of Mental Health Education Guangzhou University of Chinese MedicineGuangzhou510470China Sichuan Key Laboratory of Psychology and Behavior of Discipline Inspection and Supervision Sichuan Normal UniversityChengdu610066China

Background:In recent years,online trolling has garnered significant attention due to its detrimental effects on mental health and social *** current study examined the influence of peer victimization on adolescent online trolling behavior,proposing that hostile attribution bias mediated this relationship and that trait mindfulness moderated both the direct and indirect ***:A total of 833 Chinese adolescents completed the measurements of peer victimization,hostile attribution bias,trait mindfulness,and online *** mediation analysis was performed to examine the relationships between these ***:After controlling for gender and residential address,the study found a significant positive correlation between peer victimization and online trolling,with hostile attribution bias serving as a *** addition,trait mindfulness moderated the direct relationship between peer victimization and online ***,the effect of peer victimization on online trolling was attenuated when adolescents had high levels of trait *** results of the study emphasized the joint role of peer and personal factors in adolescents’online trolling behavior and provide certain strategies for intervening in adolescents’online trolling ***:The results of the study suggest that strategies focusing on peer support and mindfulness training can have a positive impact on reducing online trolling behavior,promoting adolescents’mental health,and their long-term development.

关键词： Online trolling peer victimization hostile attribution bias trait mindfulness adolescent

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妊娠糖尿病孕妇早产风险的预测模型构建与验证

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中国优生与遗传杂志 2024年第8期32卷 1626-1630页

作者：曾文玉王泯蓉邓夏高靖电子科技大学医学院附属绵阳医院·绵阳市中心医院妇产科四川绵阳621000

目的分析妊娠糖尿病孕妇发生早产的影响因素,并构建预测模型。方法回顾性分析2022年1月至2023年10月电子科技大学医学院附属绵阳医院·绵阳市中心医院妇产科收治的165例妊娠糖尿病孕妇,根据孕妇是否发生早产将其分为早产组(43例)和足月... 详细信息

目的分析妊娠糖尿病孕妇发生早产的影响因素,并构建预测模型。方法回顾性分析2022年1月至2023年10月电子科技大学医学院附属绵阳医院·绵阳市中心医院妇产科收治的165例妊娠糖尿病孕妇,根据孕妇是否发生早产将其分为早产组(43例)和足月组(122例)。收集所有孕妇的临床资料,通过多因素Logistic回归分析探讨与妊娠糖尿病孕妇早产相关的危险因素,构建预测模型并进行验证。结果妊娠糖尿病孕妇早产的发生率为26.06%(43/165)。经多因素Logistic回归分析显示,孕妇年龄及孕前BMI增加、妊娠高血压、流产史、早产史、孕晚期外周血白细胞水平≥10×10^(9)/L、OGTT空腹血糖≥5.1 mmol/L均是其发生早产的危险因素(P<0.05);据此构建列线图的模型ROC曲线下面积(AUC)为0.882(95%CI:0.814~0.931),提示该模型具有良好的预测效能;Hosmer-Lemeshow检验结果中χ^(2)=0.652,P=0.730,校准曲线与标准曲线表现出良好的一致性。结论本研究确定了与妊娠糖尿病孕妇发生早产有关的7项指标并构建相关模型,有助于临床筛选高风险孕妇,减少早产的发生。

关键词：妊娠糖尿病早产危险因素列线图模型

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甘草多糖对ETEC诱导断奶腹泻仔猪肠道损伤及肠道菌群的调控机制

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中国兽医学报 2024年第4期44卷 740-747,833页

作者：曾雯玉肖乐刘峻源韩雯珏汪芹刘彦泠范誉肖雄王自力西南大学动物医学院重庆北碚400715 浙江大学动物医学中心浙江杭州310058

将24头21日龄断奶仔猪随机分为空白组(Con)、模型组(Mod)和甘草多糖组(GP),连续14d给GP组灌服甘草多糖水溶液(1mL/kg,10g/L),其余组灌服等量无菌水,第15天给Mod组、GP组仔猪按1mL/kg连续3d灌服1011 CFU/mL的产肠毒素大肠杆菌(enterotoxi... 详细信息

将24头21日龄断奶仔猪随机分为空白组(Con)、模型组(Mod)和甘草多糖组(GP),连续14d给GP组灌服甘草多糖水溶液(1mL/kg,10g/L),其余组灌服等量无菌水,第15天给Mod组、GP组仔猪按1mL/kg连续3d灌服1011 CFU/mL的产肠毒素大肠杆菌(enterotoxigenic Escherichia coli,ETEC)菌液,GP组继续灌服甘草多糖水溶液。分别记录各组仔猪腹泻评分、HE法检测肠道组织病理学变化、实时荧光定量PCR检测肠道组织IL-1β、IL-6、IL-8 mRNA水平、微生物宏基因组学分析肠道菌群变化情况、Western blot检测肠道组织NF-κB/MAPK信号通路相关蛋白水平。结果显示,与Con组相比,ETEC感染后Mod组腹泻评分极显著升高(P<0.01),肠道组织结构破坏,大量肠绒毛脱落,V/C值极显著下降(P<0.01),炎性因子IL-1β、IL-6和IL-8mRNA水平极显著升高(P<0.01),变形菌门极显著上调(P<0.01),厚壁菌门极显著下调(P<0.01),乳酸菌属下调,梭菌属上调,肠道组织p-JNK/JNK、p-ERK/ERK、p-p38/p38、p-p65/p65和p-IκBα/IκBα比值极显著升高(P<0.01);与Mod组相比,GP组仔猪腹泻评分极显著降低(P<0.01),肠道结构较完整,仅有少量肠绒毛脱落,V/C值极显著升高(P<0.01),炎性因子IL-6和IL-8 mRNA水平显著或极显著降低(P<0.05或P<0.01),变形菌门极显著下调(P<0.01),厚壁菌门极显著上调(P<0.01),乳酸菌属上调,梭菌属下调,肠道组织p-JNK/JNK、p-ERK/ERK、p-p38/p38、p-p65/p65和p-IκBα/IκBα比值显著或极显著降低(P<0.05或P<0.01)。微生物组学筛选出各组可能的标记物种分别为Con组的Lactobacillus、Mod组的Fusobacterium、GP组的Rothia和Eubacterium。结果表明,甘草多糖可有效缓解ETEC诱导的断奶仔猪腹泻,改善ETEC感染引起的肠道菌群紊乱,提高有益菌丰度,降低有害菌丰度,并通过抑制NF-κB/MAPK信号通路的激活,缓解ETEC诱导的肠道炎性损伤。

关键词：产肠毒素大肠杆菌断奶仔猪腹泻肠道菌群 NF-κB/MAPK信号通路

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基于微生物组和宿主转录组整合分析香砂六君子汤对ETEC诱导断奶腹泻仔猪回肠损伤的调控机制

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畜牧兽医学报 2024年第2期55卷 797-808页

作者：肖乐刘峻源曾雯玉汪芹韩雯珏刘彦泠范誉徐雨婷杨贝妮肖雄王自力西南大学动物医学院重庆400715 浙江大学动物科学学院杭州310058 浙江大学动物医学中心杭州310058

本研究旨在探讨香砂六君子汤对产肠毒素大肠杆菌(entexotoxigenic Escherichia coli,ETEC)诱导的断奶仔猪腹泻的干预作用及其机制。将24头21日龄断奶仔猪随机分为空白组(CON)、模型组(MOD)和香砂六君子汤组(XS),连续14 d给XS组灌服香砂... 详细信息

本研究旨在探讨香砂六君子汤对产肠毒素大肠杆菌(entexotoxigenic Escherichia coli,ETEC)诱导的断奶仔猪腹泻的干预作用及其机制。将24头21日龄断奶仔猪随机分为空白组(CON)、模型组(MOD)和香砂六君子汤组(XS),连续14 d给XS组灌服香砂六君子汤(1 mL·kg^(-1),1 g·mL^(-1)),其余组灌服等量无菌水,第15天给MOD组、XS组仔猪按1 mL·kg^(-1)连续3 d灌服1011 CFU·mL^(-1) ETEC菌液,XS组继续灌服香砂六君子汤。分别记录各组仔猪腹泻评分,HE法检测回肠组织病理学变化,实时荧光定量PCR检测回肠组织IL-1β、IL-6、IL-8 mRNA水平,转录组学分析回肠组织RNA差异表达情况,微生物宏基因组学分析回肠菌群变化情况,Western blot检测回肠组织p-p38/p38、p-ERK/ERK、p-JNK/JNK蛋白水平。结果表明,灌服ETEC后,MOD组腹泻评分极显著高于CON组(P<0.01),回肠组织结构破坏,V/C值极显著下降(P<0.01),且IL-1β、IL-6和IL-8 mRNA表达量极显著升高(P<0.01),肠道菌群门水平上变形菌门极显著上调(P<0.01),厚壁菌门极显著下调(P<0.01),属水平上乳酸菌属下调,志贺菌属上调,回肠组织p-p38/p38和p-JNK/JNK比值显著或极显著升高(P<0.05或P<0.01)。与MOD组相比,XS组腹泻评分极显著下降(P<0.01),回肠组织结构完整,V/C值极显著升高(P<0.01),回肠组织IL-1β、IL-6和IL-8 mRNA表达量显著或极显著降低(P<0.05或P<0.01),肠道菌群门水平上变形菌门极显著下调(P<0.01),厚壁菌门极显著上调(P<0.01),属水平上乳酸菌属上调,志贺菌属下调,回肠组织p-p38/p38和p-ERK/ERK比值极显著降低(P<0.01)。肠道组织基因转录组学筛选出与炎症免疫相关的差异显著的10个基因,分别为TNFAIP8L2、TRIM67、CXCL2、EGF、NOX1、CCL28、FABP2、FABP6、IL1RAP和CEBPB。微生物组学筛选出各组可能的标志物种分别为CON组的Lactobacillaceae,MOD组的Shigella,XS组的Deinococcus和Eubacterium。综上所述,香砂六君子汤可有效缓解ETEC诱导的断奶仔猪腹泻,提高肠道菌群中有益菌的丰度,逆转ETEC诱发的菌群结构的改变,并可通过抑制MAPK信号通路的激活,从而缓解ETEC诱导的肠道炎性损伤。

关键词：香砂六君子汤产肠毒素大肠杆菌断奶仔猪腹泻肠道菌群转录组学 MAPK信号通路

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Survey of Psychological States of Living Related Kidney Donors after Renal Transplantation

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器官移植内科学杂志 2009年第2期4卷 82-87页

作者： wenyu Zhao Li zeng Youhua Zhu Liming Wang Meisheng Zhou Shu Han Lei Zhang Institute of Organ Transplantation of PLA Changzheng Hospital Second Military Medical University Shanghai 200003 China

Objective To survey psychological states of living related kidney donors after renal transplantation. Methods Between January 2003 and January 2007, 56 consecutive donors were interviewed preoperatively based on a 22- item questionnaire. Objective assessment of social support, quality of life, anxiety and depression was done with "Social support rating scale", "SF-36", "Beck's depression inventory" and "selfrating anxiety scale (SAS)" questionnaires from 6 months to 4 years postoperatively. Results volunteered for donation All donors had without pressure from family or recipient. Subject supports and objective supports of the donors were preferable and the utility of supports was poor. The donors showed a higher quality of life. There were no major depressive or anxiety disorders following donation. Conclusion All donors had a good psychological state after renal transplantation. More attention should be paid to mental health of the donors. Improving social support could be considered a good way to enhance their quality of life.

关键词：器官移植术医学临床外科手术学

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器官移植内科学杂志 2008年第1期3卷 12-16页

作者： wenyu Zhao Li zeng Youhua Zhu Li Ming Wang Meisheng Zhou Peng Han Lei Zhang Organ Transplantation Institute of PLA Changzheng Hospital The 2nd Military Medical University Shanghai 200003 China

Objective To summarize one-center clinical experience in living related donor kidney transplantation. Methods Eight-three living related donor kidney transplantations were performed at our center. Potential living related donors underwent fully preoperatively medical evaluation, including psychical evaluation. Except for 4 cases being donated by spouse, the others were donated by blood relationship donors. Ten donors underwent laparoscopic nephrectomy, and the others underwent open nephrectomy. Except for one case being donated by twin, immunosuppressive protocols consisting of CsA/FK506, MMF/Aza and steroid were used. Results No delayed graft function recovery (DGF) occurred. Acute rejection (AR) occurred in 8 recipients. All cases were reversed successfully by high dose of intravenous methylprednisolone or polyclonal anti-T-cell antibodies. After follow-up for 1 month to 8 years, 81 recipients with 81 grafts survived yet and kept normal kidney function without impairment of life quality. Two recipients died: one due to serious pulmonary infection, and another due to cryptococcal meningoencephalitis. Conclusion Both psychological and physical assessment of the donor and recipient are critical for the success. Surgeons should choose their most familiar way to perform the nephrectomy. The period of pre-transplantation dialysis should be shortened and the operation should be performed early. During the early period postoperatively, the dosage of immunosuppressants should be as high as that in cadaveric kidney transplantation. But lower-dose of sustained immunosuppressants could be used thereafter.

关键词：活体亲属供者肾移植技术临床分析手术治疗

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“数字化赋能”视阈下制造业技术技能型人才需求矛盾及对策研究

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实验技术与管理 2020年第5期37卷 212-214页

作者：曾文瑜闵旭光九江职业大学机电工程学院江西九江332000 江西科技师范大学材料与机电学院江西南昌330000

"数字化赋能"是制造业转型升级的趋势,同时对职业技能型人才提出了更高要求。文章结合"数字化赋能"对制造业带来的挑战和机遇,对我国制造业职业技能型人才现状及未来需求进行了分析,以期对加快制造业技术技能型人才培养、提升劳动者素... 详细信息

"数字化赋能"是制造业转型升级的趋势,同时对职业技能型人才提出了更高要求。文章结合"数字化赋能"对制造业带来的挑战和机遇,对我国制造业职业技能型人才现状及未来需求进行了分析,以期对加快制造业技术技能型人才培养、提升劳动者素质、促进制造业崛起、提升经济发展动力等有借鉴意义。

关键词：数字化赋能装备制造业职业教育人才需求产业升级

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Comparative Study on Different Methods for Prediction of Thermal Insulation Performance of Thermal Barrier Coating Used on Turbine Blades

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Journal of Thermal Science 2024年第1期33卷 172-189页

作者： ZHANG Zhixin zeng Wu ZHANG Xiaodong zeng Yuntao Advanced Gas Turbine Laboratory Institute of Engineering ThermophysicsChinese Academy of SciencesBeijing 100190China Key Laboratory of Advanced Energy and Power Institute of Engineering ThermophysicsChinese Academy of SciencesBeijing 100190China Innovation Academy for Light-duty Gas Turbine Chinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

As turbine inlet temperature gets higher and higher,thermal barrier coating(TBC) is more and more widely used in turbine *** turbine blades with TBC,it is of great significance to evaluate the temperature distribution of its substrate metal quickly and accurately,especially during the design *** different degrees of simplification such as whether to consider the change of the geometric size of the fluid domain by TBC and whether to consider the planar heat conduction in TBC,three different methods used in conjugate heat transfer(CHT) simulation to model the TBC of the turbine blades have been developed and widely used by ***,little research has been conducted to investigate the influence of the three methods on the temperature distribution of turbine *** fill this gap,three geometric models were *** are a solid conduction model with a substrate metal layer and a TBC layer,a transonic turbine vane with internal cooling and TBC,and a plate cylindrical film hole cooling model with *** methods were used in these geometric models and their differences were carefully analyzed and *** result shows that for the conduction model used in this paper,with the same TBC surface temperature distribution,the difference between the three methods is very small and can be *** a transonic turbine vane with internal cooling,regarding the local maximum temperature of the substrate-TBC interface,the largest difference between the method in which TBC is considered as a thermal resistance or a virtual layer of cells and the method in which three-dimensional heat conduction equation of TBC is solved occurs at the trailing *** difference near the leading edge is below *** employed to the film cooling model,the difference of the laterally averaged temperature of the substrate-TBC interface can be 8 K which is mainly due to the change of the length to diameter ratio of the film cooling hole by *** the substrate

关键词： turbine blade thermal barrier coating conjugate heat transfer film cooling hole

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Nested Saturated Control of Uncertain Complex Cascade Systems Using Mixed Saturation Levels

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IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1163-1174页

作者： Meng Li Zhigang zeng Wuhan National Laboratory for Optoelectronics Wuhan 430074 School of Artificial Intelligence and Automation Huazhong University of Science and TechnologyWuhan 430074China School of Artificial Intelligence and Automation Huazhong University of Science and TechnologyWuhan 430074 Key Laboratory of Image Processing and Intelligent Control of Education Ministry of China Wuhan 430074China

This study addresses the problem of global asymptotic stability for uncertain complex cascade systems composed of multiple integrator systems and non-strict feedforward nonlinear systems. To tackle the complexity inherent in such structures, a novel nested saturated control design is proposed that incorporates both constant saturation levels and state-dependent saturation levels. Specifically, a modified differentiable saturation function is proposed to facilitate the saturation reduction analysis of the uncertain complex cascade systems under the presence of mixed saturation levels. In addition, the design of modified differentiable saturation function will help to construct a hierarchical global convergence strategy to improve the robustness of control design scheme. Through calculation of relevant inequalities, time derivative of boundary surface and simple Lyapunov function,saturation reduction analysis and convergence analysis are carried out, and then a set of explicit parameter conditions are provided to ensure global asymptotic stability in the closed-loop systems. Finally, a simplified system of the mechanical model is presented to validate the effectiveness of the proposed method.

关键词： method saturation differentiable

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Aggregation-regulated bioreduction process of graphene oxide by Shewanella bacteria

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Chinese Journal of Chemical Engineering 2024年第5期69卷 56-62页

作者： Kaixin Han Yibo zeng Yinghua Lu Ping zeng Liang Shen Department of Chemical and Biochemical Engineering College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China Pen-Tung Sah Institute of Micro-Nano Science and Technology Xiamen UniversityXiamen 361005China Chinese Research Academy of Environmental Sciences Beijing 100012China

The bioreduction of graphene oxide(GO)using environmentally functional bacteria such as Shewanella represents a green approach to produce reduced graphene oxide(rGO).This process differs from the chemical reduction that involves instantaneous molecular *** bioreduction,the contact of bacterial cells and GO is considered the rate-limiting *** reveal how the bacteria-GO integration regulates rGO production,the comparative experiments of GO and three Shewanella strains were carried ***-transform infrared spectroscopy,X-ray photoelectron spectroscopy,Raman spectroscopy,and atomic force microscopy were used to characterize the reduction degree and the aggregation *** results showed that a spontaneous aggregation of GO and Shewanella into the condensed entity occurred within 36 h.A positive linear correlation was established,linking three indexes of the aggregation potential,the bacterial reduction ability,and the reduction degree(ID/IG)comprehensively.

关键词： Graphene oxide Reduced graphene oxide Bioreduction Aggregation Shewanella

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