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技术相关性、并购交易规模与企业创新绩效

科技和产业 2024年第13期24卷 77-84页

作者：姚文语张琰飞吉首大学商学院湖南吉首416000

以2015—2020年部分上市公司为样本,采用相对应年份相关数据对并购双方技术相关性和企业创新绩效间的关系进行实证分析,并研究并购交易规模的调节作用。研究发现:并购双方技术相似性和技术互补性与企业创新绩效间呈显著倒“U”型关系,... 详细信息

以2015—2020年部分上市公司为样本,采用相对应年份相关数据对并购双方技术相关性和企业创新绩效间的关系进行实证分析,并研究并购交易规模的调节作用。研究发现:并购双方技术相似性和技术互补性与企业创新绩效间呈显著倒“U”型关系,技术跨界性对企业创新绩效不具有显著影响;并购交易规模负向调节技术相似性与企业创新绩效间的关系。

关键词：技术并购技术相关性交易规模创新绩效

基于双结构模糊PID的无创呼吸机压力控制研究与设计

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计算机与数字工程 2024年第4期52卷 1045-1049,1130页

作者：魏立峰姚文宇周成广沈阳化工大学信息工程学院沈阳110021 沈阳迈思医疗科技有限公司沈阳110021

无创呼吸机是呼吸医疗产品中使用非常广泛的医疗设备,其压力控制是整个设备的基础和核心,关系到通气效果、舒适度甚至患者的呼吸安全。在对控制系统进行算法设计之前对无创呼吸机整体系统进行了分析、研究,根据呼吸机系统配置的电机性能... 详细信息

无创呼吸机是呼吸医疗产品中使用非常广泛的医疗设备,其压力控制是整个设备的基础和核心,关系到通气效果、舒适度甚至患者的呼吸安全。在对控制系统进行算法设计之前对无创呼吸机整体系统进行了分析、研究,根据呼吸机系统配置的电机性能,设计了呼气与吸气阶段模型不一致两种情况下的双结构模糊PID控制,提高了压力控制的稳定性,解决了由产品电机性能所引起的呼气压力不可控问题,对于呼吸机产品的控制效果与实际应用方面有了很大的改进。

关键词：呼吸机压力控制模糊控制模糊PID

基于DCE-MRI影像组学列线图预测三阴性乳腺癌血管生成拟态表达状态的研究

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蚌埠医学院学报 2024年第4期49卷 425-430页

作者：谢宗玉姚文宇杨静茹张舒妮刘宏德蚌埠医科大学第一附属医院放射科安徽蚌埠233004 蚌埠医科大学安徽蚌埠233030 东南大学生物科学与医学工程学院江苏南京214135

目的:探讨基于动态对比增强磁共振成像(DCE-MRI)影像组学联合临床特征构建的列线图在预测三阴性乳腺癌(TNBC)病人血管生成拟态(VM)表达状态中的价值。方法:回顾性分析术前经DCE-MRI检查且经病理证实的94例乳腺癌病人,以7∶3的比例随机... 详细信息

目的:探讨基于动态对比增强磁共振成像(DCE-MRI)影像组学联合临床特征构建的列线图在预测三阴性乳腺癌(TNBC)病人血管生成拟态(VM)表达状态中的价值。方法:回顾性分析术前经DCE-MRI检查且经病理证实的94例乳腺癌病人,以7∶3的比例随机分配训练集(n=65)和测试集(n=29)。选择DCE-MRI第2期勾画病灶最大层面。通过f-calssif函数、最小绝对收缩和选择算子回归筛选最优特征,通过支持向量机(SVM)构建DCE-MRI影像组学模型。通过单因素、多因素logistic回归筛选临床独立预测因子构建临床模型,选择DCE-MRI模型Rad-score联合临床独立预测因素建立列线图模型。结果:训练集中,VM表达阳性和阴性病人的有无腋窝淋巴结(ALN)转移、MRI最大径差异、肿瘤边缘状态均有统计学意义(P<0.05~P<0.01)。列线图模型其训练集AUC、敏感度、特异度及准确度分别为0.880、82.4%、89.6%及98.5%;测试集分别为0.869、87.5%、81.0%及82.8%。列线图模型在判断训练集、测试ALN转移结果与理想模型的一致性较好(P<0.05)。结论:基于DCE-MRI影像组学列线图可作为一种准确、无创方法用于预测术前TNBC病人VM表达水平。

关键词：乳腺肿瘤血管生成拟态表达影像组学列线图

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医用一次性防护服号型规格检测结果差异探究

中国纤检 2024年第4期 84-86页

作者：高娜曹孙上张玲姚文宇李岩峰联勤保障部队药品仪器监督检验总站北京100071

本文探究医用一次性防护服松紧带在不施加外力的自然收缩状态和拉伸至极限状态对产品质量检测的影响。选取10件不同号型规格的医用一次性防护服,根据GB 19082—2009标准的要求,分别在样品松紧带不施加外力的自然收缩状态和拉伸至极限状... 详细信息

本文探究医用一次性防护服松紧带在不施加外力的自然收缩状态和拉伸至极限状态对产品质量检测的影响。选取10件不同号型规格的医用一次性防护服,根据GB 19082—2009标准的要求,分别在样品松紧带不施加外力的自然收缩状态和拉伸至极限状态进行号型规格的检测,并对比松紧带的弹性伸长比。结果发现3件样品的号型规格在松紧带不施加外力的自然收缩状态下合格,拉伸至极限状态不合格;7件样品的号型规格在两种状态下均不合格。该研究旨在提高生产企业与检测机构对医用一次性防护服的相关指标理解的重视程度,为提升检测规范性提供依据与参考。

关键词：医用一次性防护服号型规格松紧带

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Longitudinal Relations between Rejection Sensitivity and Socio-Emotional Adjustment in Chinese Children: Moderating Effect of Emotion Regulation

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Longitudinal Relations between Rejection Sensitivity and Soc...

Engineered extracellular vesicles efficiently deliver CRISPR-Cas9 ribonucleoprotein(RNP)to inhibit herpes simplex virus1 infection in vitro and in vivo

第二十三届全国心理学学术会议

作者： Zhang Wen yao wenyu Dong Qiyiru Ding Xuechen Institute of Psychology Chinese Academy of Sciences Department of Psychology University of Chinese Academy of Sciences Department of Psychology Shanghai Normal University

As one of the important mechanisms that link individual rejection experiences to maladjustment in various domains, rejection sensitivity(RS) is referred to a cognitive-affective disposition to expect, perceive, and/or overreact to the implied or overt rejection cues anxiously or angrily. The present study collected one-year longitudinal data from 590 children’s rejection sensitivity and socio-emotional functioning through multi-source assessment(i.e.,self-reports and peer nominations) to examine the longitudinal relationships between rejection sensitivity and emotional and social difficulties, and explore the moderation effect of emotion regulation. Social problems include peer rejection and peer victimization, and emotional problems include depression, loneliness, social anxiety, and general self-worth. The results indicated that:(1) Boys had significantly higher scores on peer rejection and peer victimization than girls. Children in middle school had significantly higher scores on depression, loneliness, and social anxiety than children in elementary school, and lower scores on general self-worth than children in elementary school.(2) After controlling for the effects of gender and grade, rejection sensitivity at Time 1 significantly predicted higher levels of emotional problems at Time 2, but did not significantly predict peer problems at Time 2;emotion regulation at Time 1 negatively and significantly predicted emotional and peer problems at Time 2.(3) After controlling for the effects of gender, grade, and rejection sensitivity, the relationships between rejection sensitivity and emotional and peer problems were moderated by emotion regulation. The follow-up simple effects analyses indicated that for children with low emotion regulation, rejection sensitivity at Time 1 positively predicted emotional problems at Time 2(β =.21, p <.01) and peer problems at Time 2(β =.12, p <.01). However, for children with high emotion regulation, these effects were attenuated. T

关键词： rejection sensitivity emotional problems peer problems emotion regulation

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1362-1379页

作者： Yuanda Wan Liren Li Ruilin Chen Jiajia Han Qiyun Lei Zhipeng Chen Xiaodong Tang wenyu Wu Shuwen Liu Xingang yao NMPA Key Laboratory for Research and Evaluation of Drug Metabolism Guangdong Provincial Key Laboratory of New Drug ScreeningSchool of Pharmaceutical SciencesSouthern Medical UniversityGuangzhou 510515China Center of Clinical Pharmacy Nanfang HospitalSouthern Medical UniversityGuangzhou 510515China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhou 510060China Key Laboratory of Infectious Diseases Research in South China(Southern Medical University) Ministry of EducationGuangzhou 510515China

Extracellular vesicles(EVs)have recently emerged as a promising delivery platform for CRISPR/Cas9 ribonucleoproteins(RNPs),owing to their ability to minimize off-target effects and immune ***,enhancements are required to boost the efficiency and safety of Cas9 RNP enrichment within *** response,we employed the Fc/Spa interaction system,in which the human Fc domain was fused to the intracellular domain of PTGFRN-Δ687 and anchored to the EV ***,the B domain of the Spa protein was fused to the C domain of cargos such as Cre or *** to the robust interaction between Fc and Spa,this method enriched nearly twice the amount of cargo within the *** loaded with spCas9 RNP targeting the HSV1 genome exhibited significant inhibition of viral replication in vitro and in ***,following neuron-targeting peptide RVG modification,the in vivo dosage in neural tissues substantially increased,contributing to the clearance of the HSV1 virus in neural tissues and exhibiting a lower off-target *** findings establish a robust platform for efficient EV-based SpCas9 delivery,offering potential therapeutic advantages for HSV1 infections and other neurological disorders.

关键词： Extracellular vesicles CRISPR/Cas9 Ribonucleoproteins PTGFRN Fc/Spa HSV1 Neuron-targeting Delivery

Enhancing the Efficiency and Durability of Perovskite Solar Cells by Donor-Acceptor Covalent Organic Framework with Thiazolo[5,4-d]thiazole Unit

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CCS Chemistry 2024年第7期6卷 1721-1730页

作者： Liyi yao Shuainan Liu Lin Li Bangdi Ge wenyu Jiao Siyu Zong Xiaowei Song Donglei Zhou Zhiqiang Liang State Key Lab of Inorganic Synthesis and Preparative Chemistry College of ChemistryJilin UniversityChangchun 130012 State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012 Electron Microscopy Center Jilin UniversityChangchun 130012

Donor-Acceptor(D-A)alignment is considered a productive strategy to improve the charge separation efficiency of covalent organic frameworks(COFs)and enhance the charge-transfer yield(CTY)of ***,organic molecules containing heteroatoms can produce coordination interaction with PbI2 of perovskite precursor to affect the crystallization process,thereby impeding the decomposition and improving the stability of perovskite ***,a thiazolo[5,4-d]thiazole(TZ)-based D-A type COF_(TPDA-TZDA) was designed and synthesized from N,N,N′,N′-tetrakis(4-aminophenyl)-1,4-benzenediamine(TPDA)and 4,4′-(thiazolo[5,4-d]thiazole-2,5-diyl)dibenzaldehyde(TZDA).Upon incorporation into the FAPbI3 layer,COF_(TPDA-TZDA) not only restrained the perovskite defects and enhanced the grain size of perovskite films through the coordination effect of the N atoms of TZDA but also ameliorated the charge transport within the perovskite film,which was the benefit of the D-A structure of COF_(TPDA-TZDA).As a result,incorporation of COF_(TPDA-TZDA) into the perovskite solar cells(PSCs)led to a remarkable power conversion efficiency(PCE)of up to 23.51%.Furthermore,even after being stored in high relative humidity(RH≈60%)for 480 h,these PSCs maintained over 90.55%of their original *** work sets the foundation for the development of highly efficient and stable PSCs by utilizing TZ-based D-A type COFs.

关键词： thiazolo[5,4-d]thiazole perovskite solar cells donor-acceptor covalent organic frameworks charge-transfer

Critical Solvation Structures Arrested Active Molecules for Reversible Zn Electrochemistry

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Nano-Micro Letters 2024年第8期16卷 64-78页

作者： Junjie Zheng Bao Zhang Xin Chen wenyu Hao Jia yao Jingying Li Yi Gan Xiaofang Wang Xingtai Liu Ziang Wu Youwei Liu Lin Lv Li Tao Pei Liang Xiao Ji Hao Wang Houzhao Wan Hubei Yangtze Memory Laboratories Wuhan 430205People’s Republic of China Hubei Key Laboratory of Micro‑Nanoelectronic Materials and Devices School of MicroelectronicsHubei UniversityWuhan 430062People’s Republic of China School of Physical and Mathematical Sciences Nanyang Technological UniversitySingapore 637371Singapore School of Optical and Electronic Information Huazhong University of Science and TechnologyWuhan 430074People’s Republic of China Institute of Optoelectronics Technology China Jiliang UniversityHangzhou 310018People’s Republic of China

Aqueous Zn-ion batteries(AZIBs)have attracted increasing attention in next-generation energy storage systems due to their high safety and ***,the side reactions,dendrites and hydrogen evolution effects at the zinc anode interface in aqueous electrolytes seriously hinder the application of aqueous zinc-ion ***,we report a critical solvation strategy to achieve reversible zinc electrochemistry by introducing a small polar molecule acetonitrile to form a“catcher”to arrest active molecules(bound water molecules).The stable solvation structure of[Zn(H_(2)O)_(6)]^(2+)is capable of maintaining and completely inhibiting free water ***[Zn(H_(2)O)_(6)]^(2+)is partially desolvated in the Helmholtz outer layer,the separated active molecules will be arrested by the“catcher”formed by the strong hydrogen bond N-H bond,ensuring the stable desolvation of Zn^(2+).The Zn||Zn symmetric battery can stably cycle for 2250 h at 1 mAh cm^(-2),Zn||V_(6)O_(13) full battery achieved a capacity retention rate of 99.2%after 10,000 cycles at 10 A g^(-1).This paper proposes a novel critical solvation strategy that paves the route for the construction of high-performance AZIBs.

关键词： Zinc-ion battery Critical solvation Helmholtz layer Arrest active molecule Reversible zinc anode

教师在线培训中社会比较性反馈机制构建与应用研究

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电化教育研究 2024年第9期45卷 97-103,112页

作者：马宁路瑶阎雯玉北京师范大学教育学部北京100875

教师在线培训是教师专业发展的重要途径之一。优质的在线异步协作学习能够有效促进教师在线培训效果,但非实时性等特点使得在线异步协作学习面临挑战。研究基于社会比较的视角,构建了面向在线异步协作场景的社会比较性反馈机制,包括在... 详细信息

教师在线培训是教师专业发展的重要途径之一。优质的在线异步协作学习能够有效促进教师在线培训效果,但非实时性等特点使得在线异步协作学习面临挑战。研究基于社会比较的视角,构建了面向在线异步协作场景的社会比较性反馈机制,包括在线学习活动模块、数据采集与处理模块和社会比较模块,为教师学习者提供行为、认知、交互、情感四个维度的社会比较性反馈,并通过准实验研究验证了该机制的有效性。结果表明,社会比较性反馈有助于提升教师学习者的群体协作学习绩效,并较大程度地提升了教师学习者的学习积极性和满意度。研究旨在为提升教师在线培训效果,促进教师队伍高质量建设提供理论与实践参考。

关键词：教师在线培训在线异步协作社会比较反馈群体协作学习绩效

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