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Expression and significance of MMP3 in synovium of knee joint at different stage in osteoarthritis patients

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Asian Pacific Journal of Tropical Medicine 2014年第4期7卷 297-300页

作者： Jun-Jie Chen Jie-Feng Huang wen-xi du Pei-Jian Tong Department of Orthopedics First Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine

Objective:To investigate the expression and significance of MMP-3 in synovium of knee joint at different stage in osteoarthritis(OA)***:Knee synovial tissue were collected in90 OA patients(the OA group).Patients in the OA group was divided into 3 subgroups:gradeⅠsubgroup(n=30),gradeⅡsubgroup(n=30),gradeⅢsubgroup(n=30).Thirty patients served as control group,lmmunohistochemical assay was used to detect the expression of MMP-3 protein in the knee synovial ***:MMP-3 protein was detected in all knee synovial *** expression of MMP-3 protein in the OA group was significantly higher that in the normal synovium(P<0.05),and the MMP-3 protein was mainly located in the *** was significant difference in the expression of MMP-3 protein between the gradeⅢsubgroup and the gradeⅠ,gradeⅡsubgroups(all P<0.05).The expression of MMP-3 protein was positively related to the severity of OA(r=0.912,P<0.05).Conclusions:The expression of MMP-3 protein are closely related to pathogenic mechanism of *** may be an important indicator of early diagnosis and the activity of the disease of osteoarthritis.

关键词： Osteoarthritis MMP-3 Immunohistochemical

Gear walk instability caused by brake-disc friction characteristics

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Chinese Journal of Aeronautics 2024年第2期37卷 343-359页

作者： xiaoqiong du Bin LI wen CAI Linyin LUO School of Aeronautics Northwestern Polytechnical UniversityXi’an 710072China Department of Mechanical Engineering University of MichiganAnn Arbor 48109USA AVIC General Huanan Aircraft Industry Co.Ltd. Zhuhai 519040China

A multi-body dynamic rigid-flexible coupling model of landing gear is established to study the gear walk instability caused by the friction characteristics of the brake *** validating the model with the experimental results,the influence of the landing gear structure and braking system parameters on gear walk is further *** the above factors,the slope of the graph for the friction coefficient of the brake disc and the relative velocity of brake stators and rotors is the most influential factor on gear walk *** trajectory analysis verifies that gear walk occurs when the coupling of multiple factors causes the system to exhibit an equivalent negative damping *** consider a more realistic braking case,a back propagation neural network method is employed to describe the nonlinear behavior of the friction coefficient of the brake *** the realistic nonlinear model of the friction coefficient,the maximum error in predicting the braking torque is less than 10%and the effect of the brake disc temperature on gear walk is *** results reveal that a more negative friction slope may contribute to a more severe unstable gear walk,and reducing the braking pressure is an effective approach to avoid gear walk,which provides help for future braking system design.

关键词： Gear walk Friction characteristics of brake disc Brake-induced vibration Negative damping Rigid-flexible coupling Negative slope of braking torque

Coordination of distinctive pesticide adjuvants and atomization nozzles on droplet spectrum evolution for spatial drift reduction

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Chinese Journal of Chemical Engineering 2024年第2期66卷 250-262页

作者： Shidong Xue Jingkun Han xi xi Zhong Lan Rongfu wen Xuehu Ma State Key Laboratory of Fine Chemicals Liaoning Key Laboratory of Clean Utilization of Chemical ResourcesInstitute of Chemical EngineeringSchool of Chemical EngineeringDalian University of TechnologyDalian 16024China School of Fashion and Textiles The Hong Kong Polytechnic UniversityHong Kong 999077China China Tianchen Engineering Corporation Tianjin 300400China School of Energy and Power Engineering Dalian University of TechnologyDalian 116024China

Pesticide adjuvants,as crop protection products,have been widely used to reduce drift loss and improve utilization efficiency by regulating droplet ***,the coordinated regulation mechanisms of adjuvants and nozzles on droplet spectrum remain ***,we established the relationship between droplet spectrum evolution and liquid atomization by investigating the typical characteristics of droplet diameter distribution near the *** on this,the regulation mechanisms of distinctive pesticide adjuvants on droplet spectrum were clarified,and the corresponding drift reduction performances were quantitively evaluated by wind tunnel *** shows that the droplet diameter firstly shifts to the smaller due to the liquid sheet breakup and then prefers to increase caused by droplet *** the surface tension of sprayed liquid facilitates the uniform liquid breakup and increasing the viscosity inhibits the liquid deformation,which prolong the atomization process and effectively improve the droplet *** a result,the drift losses of flat-fan and hollow cone nozzles are reduced by about 50%after adding organosilicon and vegetable oil *** contrast,the air induction nozzle shows a superior anti-drift ability,regardless of distinctive *** findings provide insights into rational adjuvant design and nozzle selection in the field application.

关键词： Pesticide drift Spray droplets Particle size distribution Spray atomization Transport processes Adjuvants

A digital twins enabled underwater intelligent internet vehicle path planning system via reinforcement learning and edge computing

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Digital Communications and Networks 2024年第2期10卷 282-291页

作者： Jiachen Yang Meng xi Jiabao wen Yang Li Houbing Herbert Song School of Electrical and Information Engineering Tianjin UniversityTianjin300072China Security and Optimization for Networked Globe Laboratory(SONG Lab) Embry-Riddle Aeronautical UniversityDaytona BeachFL32114USA

The Autonomous Underwater Glider(AUG)is a kind of prevailing underwater intelligent internet vehicle and occupies a dominant position in industrial applications,in which path planning is an essential *** to the complexity and variability of the ocean,accurate environment modeling and flexible path planning algorithms are pivotal *** traditional models mainly utilize mathematical functions,which are not complete and *** existing path planning algorithms depend on the environment and lack *** overcome these challenges,we propose a path planning system for underwater intelligent internet *** applies digital twins and sensor data to map the real ocean environment to a virtual digital space,which provides a comprehensive and reliable environment for path *** design a value-based reinforcement learning path planning algorithm and explore the optimal network structure *** path simulation is controlled by a closed-loop model integrated into the terminal vehicle through edge *** integration of state input enriches the learning of neural networks and helps to improve generalization and *** task-related reward function promotes the rapid convergence of the *** experimental results prove that our reinforcement learning based path planning algorithm has great flexibility and can effectively adapt to a variety of different ocean conditions.

关键词： Digital twins Reinforcement learning Edge computing Underwater intelligent internet vehicle Path planning

Sea-level change in coastal areas of China:Status in 2021

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Advances in Climate Change Research 2024年第3期15卷 515-524页

作者： wen-Shan LI Hui WANG wen-xi xiANG Ai-Mei WANG Wei-Qing XU Yu-xi JIANG xin-Hui WU Meng-Yuan QUAN National Marine Data and Information Service Tianjin 300171China Ocean University of Chin1 Qingdao 266100China University of Michigan‒Shanghai Jiao Tong University Joint Institute Shanghai 200030China

The sea level in coastal areas of China reached the second highest in 2021,just after that recorded in *** force and dynamic analyses based on tide gauges,satellite observations,reanalysis data and regional numerical outputs were conducted to understand these abnormally high sea levels and determine their possible *** show that the coastal sea level of China had increased at an annual rate of 3.4±0.3 mm during 1980-2021,with an acceleration of 0.06±0.02 mm per *** superposition of significant oscillations of quasi-2,3-7,quasi-9,quasi-11,quasi-19 and 20-30 years contributed to the anomalously high sea *** negative-phased El Nino/Southern Oscillation was correlated with the anomalously high sea level and the north-south anti-phase pattern of the coastal sea level in ***,phase lags of 1-4 months occurred with the sea-level *** a decadal timescale,the Pacific Decadal Oscillation(PDO)was negatively correlated with the anomalous mean sea level(MSL),and the negative-phased PDO contributed to the anomalous sea-level change in ***,the monthly MSL peaked in April and July,and the contribution of wind stress to the anomalously high sea level was 38.5%in the south of the Taiwan Strait in April and 30%along the coast of China in *** results were consistent with the tide gauge and satellite *** agreement was also observed between the coastal sea-level fingerprint and the air and sea surface temperatures.

关键词： Sealevel La Nina PDO Wind stress

Method and Practice of Trusted Embedded Computing and Data Transmission Protection Architecture Based on Android

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Chinese Journal of Electronics 2024年第3期33卷 623-634页

作者： Yichuan WANG wen GAO xinhong HEI Yanning du School of Computer Science and Engineering Xi'an University of Technology Shaanxi Key Laboratory for Network Computing and Security Technology

In recent years,the rapid development of Internet technology has constantly enriched people's daily life and gradually changed from the traditional computer terminal to the mobile *** with it comes the security problems brought by the mobile *** for Android system,due to its open source nature,malicious applications continue to emerge,which greatly threatens the data security of ***,this paper proposes a method of trusted embedded static measurement and data transmission protection architecture based on Android to reduce the risk of data leakage in the process of terminal storage and *** conducted detailed data and feasibility analysis of the proposed method from the aspects of time consumption,storage overhead and *** experimental results show that this method can detect Android system layer attacks such as self-booting of the malicious module and improve the security of data encryption and transmission process *** with the native system,the additional performance overhead is small.

关键词： Embedded computing Protocols Data security Computer architecture Encryption Internet Data communication

Corporate Credit Ratings Based on Hierarchical Heterogeneous Graph Neural Networks

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Machine Intelligence Research 2024年第2期21卷 257-271页

作者： Bo-Jing Feng xi Cheng Hao-Nan Xu wen-Fang Xue Center for Research on Intelligent Perception and Computing National Laboratory of Pattern RecognitionInstitute of AutomationChinese Academy of SciencesBeijing 100190China

order to help investors understand the credit status of target corporations and reduce investment risks,the corporate credit rating model has become an important evaluation tool in the financial *** models are based on statistical learning,machine learning and deep learning especially graph neural networks(GNNs).However,we found that only few models take the hierarchy,heterogeneity or unlabeled data into account in the actual corporate credit rating ***,we propose a novel framework named hierarchical heterogeneous graph neural networks(HHGNN),which can fully model the hierarchy of corporate features and the heterogeneity of relationships between *** addition,we design an adversarial learning block to make full use of the rich unlabeled samples in the financial *** experiments conducted on the public-listed corporate rating dataset prove that HHGNN achieves SOTA compared to the baseline methods.

关键词： Corporate credit rating hierarchical relation heterogeneous graph neural networks adversarial learning

High-precision parallel computing model of solute transport based on GPU acceleration

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Journal of Hydrodynamics 2024年第1期36卷 202-212页

作者： Shang-hong Zhang Rong-qi Zhang wen-da Li xi-yan Yang Yang Zhou School of Water Resources and Hydropower Engineering North China Electric Power UniversityBeijing102206China Hubei Key Laboratory of Intelligent Yangtze and Hydroelectric Science China Yangtze Power Co.Ltd.Yichang443133China

The scenario simulation analysis of water environmental emergencies is very important for risk prevention and control,and emergency *** quickly and accurately simulate the transport and diffusion process of high-intensity pollutants during sudden environmental water pollution events,in this study,a high-precision pollution transport and diffusion model for unstructured grids based on Compute Unified Device Architecture(CUDA)is *** finite volume method of a total variation diminishing limiter with the Kong proposed r-factor is used to reduce numerical diffusion and oscillation errors in the simulation of pollutants under sharp concentration conditions,and graphics processing unit acceleration technology is used to improve computational *** advection diffusion process of the model is verified numerically using two benchmark cases,and the efficiency of the model is evaluated using an engineering *** results demonstrate that the model perform well in the simulation of material transport in the presence of sharp ***,it has high computational *** acceleration ratio is 46 times the single-thread acceleration effect of the original *** efficiency of the accelerated model meet the requirements of an engineering application,and the rapid early warning and assessment of water pollution accidents is achieved.

关键词： Pollution transport and diffusion model parallel computing Compute Unified Device Architecture(CUDA) pollution event

Effects of Enclosure on Grassland Ecological and Economic Benefits in Northern China

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Chinese Geographical Science 2024年第1期34卷 67-78页

作者： HU Bo wen Qingke xi Fengjiang LI Mengyao WANG Libing REN Yuejuan Aerospace Information Research Institute Chinese Academy of SciencesBeijing100094China University of Chinese Academy of Sciences Beijing100049China Inner Mongolia Remote Sensing Center Co. Ltd.Huhhot010000China xilinhot the Maodeng pasture Xilinhot026000China China University of Mining and Technology Xuzhou221116China Shanxi Provincial Key Lab of Resources Environment and Disaster MonitoringCoal Geological Geophysical Exploration Surveying&Mapping Institute of Shanxi ProvinceJinzhong030600China

Grasslands in northern China serve the country as both an ecological barrier and a livestock production ***,installing enclosures has been becoming the major grassland restoration measure adopted by many local ***,the effects of restoration on both ecological and production benefits of grassland remain unclear for implemented grassland restoration ***,a representative rangeland in northern China,the Maodeng pasture in Inner Mongolia Autonomous Region was selected as the study area,and remote sensing monitoring analyses were carried out to quantify the ecological benefits and economic benefits from 2015 to *** results showed that:1) in terms of ecological benefits,the grassland area with a grassland coverage rate of more than 60% accounts for 32.3% of the regional area,and 86.4% of its grassland grew significantly better than the same period in2015,showing a significant improvement in grassland *** the average amount of carbon per unit area as the ecological benefit evaluation index,it increased by 27.1% to 32.48Tg C/yr from 2015 to 2021.2) In terms of economic benefits,both theoretical grass production and livestock carrying capacity increased from 2015 to *** to 2015,the theoretical grass production in 2021 increased by 24.8% to 71 900 *** livestock carrying capacity reached 52 100 sheep units in 2021,nearly 11 000 sheep units more than that in *** the study period,multiple economic indicators(on a per capita basis of permanent residents) for the pastoral area of xilinhot City to which the Maodeng pasture belongs,have grown *** capita total income rose from 29 630 yuan(RMB) in2015 to 62 859 yuan(RMB) in *** on grassland resources to develop the pastoral ecology also broadens the potential economic development ***,the establishment of the reserve and the experiment of implanting an enclosure policy have had a significant and positive impact on Maodeng pasture’s develo

关键词： enclosure grassland ecological benefit economic benefit Maodeng pasture Inner Mongolia northern China