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Journal of Central South University 2024年第8期31卷 2872-2890页

作者： Wang, Meng Guo, Ping-ye Jin, Xin dang, Guan-jie Guo, Yi-chen li, Yi State Key laboratory for Tunnel Engineering China University of Mining and Technology-Beijing Beijing China School of Mechanics and Civil Engineering China University of Mining and Technology-Beijing Bgijing China

Every year in China, a significant number of mines are closed or abandoned. The pumped hydroelectric storage (PHS) and geothermal utilization are vital means to efficiently repurpose resources in abandoned mine. In this work, the development potentials of the PHS and geothermal utilization systems were evaluated. Considering the geological conditions and meteorological data available of Jiahe abandoned mine, a simple evaluation model for PHS and geothermal utilization was established. The average efficiency of the PHS system exceeds 70% and the regulatable energy of a unit volume is over 1.53 kW·h/m3. The PHS system achieves optimal performance when the wind/solar power ratio reaches 0.6 and 0.3 in daily and year scale, respectively. In the geothermal utilization system, the outlet temperature and heat production are significantly affected by the injection flow rate. The heat production performance is more stable at lower rate flow, and the proportion of heat production is higher in the initial stage at greater flow rate. As the operating time increases, the proportion of heat production gradually decreases. The cyclic heat storage status has obvious advantages in heat generation and cool.ng. Furthermore, the energy-saving and emission reduction benefits of PHS and geothermal utilization systems were calculated.

关键词： abandoned mine underground reservoir wind/solar energy pumped hydroelectric storage geothermal

Naoxueshu Oral liquid Accelerates Post-Craniotomy Hematoma Absorption in Patients:An Open-label,Multicenter,and Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2024年第8期30卷 675-683页

作者： HE Qiu lIN Fu-xin SU Jin-ye ZHUO l.ng-yunn ZHU Qing SUN Xiao-chuan JIAng Rong-cai YAO Zhi-gang WAng lei dang Yan-wei lIU De-zhong lIU Yang FAng wen-hua WAng Fang-yu lIN Yuan-xiang WAng An-xin WAng Deng-liang KAng De-zhi Department of Neurosurgery Neurosurgery Research InstituteThe First Affiliated Hospital of Fujian Medical UniversityFuzhou350004China Department of Neurosurgery Binhai Branch of National Regional Medical CenterThe First Affiliated HospitalFujian Medical UniversityFuzhou350209China Clinical Research and Translation Center The First Affiliated Hospital of Fujian Medical UniversityFuzhou350004China Fujian Clinical Research Center for Neurological Diseases The First Affiliated Hospital of Fujian Medical UniversityFuzhou350004China Fujian Provincial Institutes of Brain Disorders and Brain Sciences The First Affiliated Hospital of Fujian Medical UniversityFuzhou350004China Department of Neurosurgery The Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu Province215000China Department of Neurosurgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing400000China Department of Neurosurgery Tianjin Medical University General HospitalTianjin300000China Department of Neurosurgery The Third Hospital of ShijiazhuangShijiazhuang050000China Department of Neurosurgery The First College of Clinical Medical ScienceChina Three Gorges UniversityYichangHubei Province443000China Department of Neurosurgery Yichang Central People’s HospitalYichangHubei Province443000China Department of Neurosurgery Xiangyang No.1 People’s Hospital Affiliated to Hubei University of MedicineXiangfanHubei Province441100China Department of Neurosurgery Zhoukou Central HospitalZhoukouHenan Province466000China Department of Neurosurgery The Third Hospital of MianyangMianyangSichuan Province621000China Department of Neurology Beijing Tiantan HospitalCapital Medical UniversityBeijing100000China China National Clinical Research Center for Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijing100000China Department of Clinical Epidemiology and Clinical Trial Capital Medical UniversityBeijing100000China Beijing Municipal Key laboratory of Clinical

Objective To investigate whether Naoxueshu Oral liquid(NXS)could promote hematoma absorption in post-craniotomy hematoma(PCH)*** This is an open-label,multicenter,and randomized controlled trial conducted at 9 hospitals in *** aged 18–80 years with post-craniotomy supratentorial hematoma volume ranging from 10 to 30 ml or post-craniotomy infratentorial hematoma volume less than 10 ml,or intraventricular hemorrhage following cranial surgery were *** were randomly assigned at a 1:1 ratio to the NXS(10 ml thrice daily for 15 days)or control groups using a randomization code *** medical care was administered in both *** primary outcome was the percentage reduction in hematoma volume from day 1 to day *** secondary outcomes included the percentage reduction in hematoma volume from day 1 to day 7,the absolute reduction in hematoma volume from day 1 to day 7 and 15,and the change in neurological function from day 1 to day 7 and *** safety was closely monitored throughout the ***,subgroup analysis was performed based on age,gender,history of diabetes,and etiology of intracerebral hemorrhage(ICH).Results A total of 120 patients were enrolled and randomly assigned between March 30,2018 and April 15,*** patient was lost to follow-up in the control ***,there were 119 patients(60 in the NXS group and 59 in the control group)included in the *** the full analysis set(FAS)analysis,the NXS group had a greater percentage reduction in hematoma volume from day 1 to day 15 than the control group[median(Q1,Q3):85%(71%,97%)vs.76%(53%,93%),P<0.05].The secondary outcomes showed no statistical significance between two groups,either in FAS or per-protocol set(P>0.05).Furthermore,no adverse events were reported during the *** the FAS analysis,the NXS group exhibited a higher percentage reduction in hematoma volume on day 15 in the following subgroups:male patients,patients younger than 65 yea

关键词： post-craniotomy hematoma Naoxueshu Oral liquid hematoma absorption randomized controlled trial Chinese medicine

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气候变化背景下内保温砖墙热湿性能对比

东南大学学报（自然科学版） 2024年第2期54卷 441-446页

作者：党新元 Department of Civil Engineering KU LeuvenLeuven 3001Belgium

为量化气候变化背景下内保温砖墙的热湿性能,采用数值模拟软件WUFI Pro,对比湿气密闭性保温墙体、湿气透过性内保温墙体和未保温墙体,分析其在比利时鲁汶1种现状气候工况和2种未来气候工况下的冻融循环风险、霉菌滋生风险、热损失和湿负... 详细信息

为量化气候变化背景下内保温砖墙的热湿性能,采用数值模拟软件WUFI Pro,对比湿气密闭性保温墙体、湿气透过性内保温墙体和未保温墙体,分析其在比利时鲁汶1种现状气候工况和2种未来气候工况下的冻融循环风险、霉菌滋生风险、热损失和湿负荷.结果表明,湿气透过性保温墙体与湿气密闭性保温墙体的冻融风险次数由现状气候工况下的6和2次升至未来气候工况下的16和13次,且含水率显著增高,而未保温墙体无风险.湿气密闭性保温墙体在3种工况下的霉菌滋生风险都显著高于其余2种墙体,且在未来气候工况下风险更高.含保温层墙体的能耗显著低于未保温墙体,湿气透过性保温墙体与未保温墙体在未来气候工况下需要更大的湿负荷.

关键词：气候变化砖墙内保温热湿性能

Mitochondria-targeted Janus mesoporous nanoplatform for tumor photodynamic therapy

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Chinese Chemical letters 2024年第2期35卷 544-547页

作者： Min Dong Rui Tang Jing li Jiajia Zhao Yu Wang lin Ouyang Wei lu Jun Tao Meng dang Yuxia Tang Zhaogang Teng Key laboratory for Organic Electronics & Information Displays and Jiangsu Key laboratory for Biosensors Institute of Advanced MaterialsJiangsu National Synergetic Innovation Centre for Advanced MaterialsNanjing University of Post and TelecommunicationsNanjing 210023China laboratory of Molecular Imaging Department of RadiologyThe First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029China Department of Radiology The 909th HospitalSoutheast HospitalSchool of MedicineXiamen UniversityZhangzhou 363000China State Key laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringInstitute of Functional MaterialsDonghua UniversityShanghai 201620China

Photodynamic therapy(PDT)is an effective treatment method for *** the specifically accumulated of photosensitizer was very difficult in the tumor site,which greatly limited the efficacy of ***,mitochondria-targeted Janus mesoporous nanoplatform(JPMO-Pt-CTPP-ZnPc)for PDT was prepared,the nanoplatform has uniform size(275 nm)and good dispersion and *** confocal laser scanning microscopy(ClSM)revealed the signal of ZnPc of JPMO-Pt-CTPP-ZnPc were higher than JPMO-Pt-ZnPc in tumor cells,and flow cytometry results showed the cell uptake efficiency of JPMO-Pt-CTPP-ZnPc was 2.5-fold higher than that of *** revealed the modification of CTPP significantly improves the targeting ability of the *** vitro anti-tumor experiment showed the JPMO-Pt-CTPP-ZnPc significantly inhibited the growth of tumor cells upon the irradiation of low-power laser,and the survival rate of cells incubated with 60μg/ml JPMO-Pt-CTPP-ZnPc was only 3%.Simultaneously,compared with JPMO-Pt-ZnPc(not modified with mitochondria targeting molecules CTPP),the PDT efficacy of JPMO-Pt-CTPP-ZnPc was significantly better,as it has targeted mitochondria in cells.

关键词： Mesoporous materials Janus particle Photodynamic therapy Mitochondria targeting Tumor treatment

High-Al-composition AlGaN/GaN MISHEMT on Si with fT of 320 GHz

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Science China(Information Sciences) 2024年第6期67卷 459-460页

作者： Hanghai DU lu HAO Zhihong lIU Zeyu SOng Yachao ZHAng Kui dang Jin ZHOU Jing NIng Zan lI Jincheng ZHAng Yue HAO State Key laboratory of Wide Bandgap Semiconductor Devices and Integrated Technology School of MicroelectronicsXidian University Guangzhou Wide Bandgap Semiconductor Innovation Center Guangzhou Institute of TechnologyXidian University State Key laboratory of Integrated Services Networks School of Communication EngineeringXidian University

GaN-based metal-insulator-semiconductor high-electronmobility-transistors (MISHEMTs) have many excellent performances compared with the Si and Ga As counterparts,and are prime candidates for applications in communicat...

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Expression and clinical significance of pattern recognition receptor-associated genes in hand, foot and mouth disease

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Asian Pacific Journal of Tropical Medicine 2024年第4期17卷 173-183,I0001-I0003页

作者： Muqi Wang Huil.ng Deng Yuan Chen Yikai Wang Yufeng Zhang Chenrui liu Meng Zhang Ting li Shuangsuo dang Yaping li Department of Infectious Diseases The Second Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710004China Department of Pediatrics Xi'an Central HospitalXi'an 710004China Department of Infectious Diseases Xi'an Children's HospitalXi'an 710003China

Objective:To explore which pattern recognition receptors(PRRs)play a key role in the development of hand,foot,and mouth disease(HFMD)by analyzing PRR-associated ***:We conducted a comparative analysis of PRR-associated gene expression in human peripheral blood mononuclear cells(PBMCs)infected with enterovirus 71(EV-A71)which were derived from patients with HFMD of different severities and at different stages.A total of 30 PRR-associated genes were identified as significantly upregulated both over time and across different EV-A71 ***,ElISA was employed to quantify the expression of the six most prominent genes among these 30 identified genes,specifically,BST2,IRF7,IFI16,TRIM21,MX1,and ***:Compared with those at the recovery stage,the expression levels of BST2(P=0.027),IFI16(P=0.016),MX1(P=0.046)and DDX58(P=0.008)in the acute stage of infection were significantly upregulated,while no significant difference in the expression levels of IRF7(P=0.495)and TRIM21(P=0.071)was found between different stages of the *** expression levels of BST2,IRF7,IFI16 and MX1 were significantly higher in children infected with single pathogen than those infected with mixed pathogens,and BST2,IRF7,IFI16 and MX1 expression levels were significantly lower in coxsackie B virus(COXB)positive patients than the negative *** levels of one or more of BST2,IRF7,IFI16,TRIM21,MX1 and DDX58 genes were correlated with PCT levels,various white blood cell counts,and serum antibody levels that reflect disease course of *** aminotransferase was correlated with BST2,MX1 and DDX58 expression ***:PRR-associated genes likely initiate the immune response in patients at the acute stage of HFMD.

关键词： Pattern recognition receptors(PRRs) Hand,foot,and mouth disease(HFMD) Immune Enterovirus 71(EV-A71)

CO_(2)升高和增温没有稀释椴树叶片氮浓度却降低了叶片的光合能力

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Journal of Plant Ecology 2024年第3期17卷 39-48页

作者： lei Wang Jinping Zheng Gerong Wang Qing-lai dang Department of landscape Architechture Jiyang College of Zhejiang A&F UniversityZhuji 311800China Faculty of Natural Resources Management Lakehead UniversityThunder BayON P7B 5E1Canada Department of Forestry Forestry CollegeBeihua UniversityJilin 132013China

深入理解CO_(2)升高和全球变暖对植物的影响是预测植物适应性的关键。本研究以温带阔叶耐荫树种椴树(Tilia amurensis)幼苗为试验材料,研究了当前CO_(2)浓度和气温组合处理(CC)与预测的未来气候条件下CO_(2)升高和增温组合处理(FC)对植... 详细信息

深入理解CO_(2)升高和全球变暖对植物的影响是预测植物适应性的关键。本研究以温带阔叶耐荫树种椴树(Tilia amurensis)幼苗为试验材料,研究了当前CO_(2)浓度和气温组合处理(CC)与预测的未来气候条件下CO_(2)升高和增温组合处理(FC)对植物光合驯化的影响模式。结果发现,FC处理促进了椴树地上部分的生长,降低了叶片的光合能力(最大羧化速率和最大电子传递速率),也降低了椴树光合作用生化限制中从羧化限制向电子传递限制过渡点的光合速率。FC处理没有改变叶片氮浓度,但是提高了单株叶片的含氮量和光合氮素利用效率。这些结果表明,在椴树适应未来气候条件中发挥重要的作用的可能是叶片的氮素利用效率,而非其光合能力。本研究为理解椴树的光合驯化特征提供了新的见解,研究结果也可以用于预测椴树在未来气候条件下可能的表现。

关键词：椴树(Tilia amurensis) 光合驯化 CO_(2) 升高和增温温带阔叶树氮素浓度

A review on DFACS(II):Model.ng and analysis of disturbances and noises

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Chinese Journal of Aeronautics 2024年第5期37卷 120-147页

作者： Chenglei YUE Bohan JIAO Zhaohui dang Xiaokui YUE Yonghe ZHAng Yuanqing XIA li DUAN Qinglei HU Qifan lIU Pengcheng WAng Ming GUO Zhansheng DUAN Bing CUI Chu ZHAng Xiaodong SHAO School of Astronautics Northwestern Polytechnical UniversityXi’an 710072China Innovation Academy for Microsatellites Chinese Academy of SciencesShanghai 710699China School of Automation Beijing Institute of TechnologyBeijing 100081China Institute of Mechanics Chinese Academy of SciencesBeijing 710043China School of Automation Science and Electrical Engineering Beihang UniversityBeijing 100191China School of Automation Science and Engineering Xi’an Jiaotong UniversityXi’an 710049China

This paper presents Part II of a review on DFACS,which specifically focuses on the model.ng and analysis of disturbances and noises in *** Part I,the system composition and dynamics model of the DFACS were *** this paper,we discuss the effects of disturbance forces and noises on the system,and summarize various analysis and model.ng methods for these interferences,including the integral method,frequency domain analysis method,and magnitude evaluation *** analyzing the impact of disturbances and noises on the system,the paper also summarizes the system’s performance under slight ***,we highlight current research difficulties in the field of DFACS noise ***,this paper provides valuable insights into the model.ng and analysis of disturbances and noises in DFACSs,and identifies key areas for future research.

关键词： Drag-free DFACS Disturbance Analysis Noise Analysis Frequency Domain Analysis Performance Evaluation

A review on DFACS(I):System design and dynamics model.ng

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Chinese Journal of Aeronautics 2024年第5期37卷 92-119页

作者： Bohan JIAO Qifan lIU Zhaohui dang Xiaokui YUE Yonghe ZHAng Yuanqing XIA li DUAN Qinglei HU Chenglei YUE Pengcheng WAng Ming GUO Zhansheng DUAN Bing CUI Chu ZHAng Xiaodong SHAO School of Astronautics Northwestern Polytechnical UniversityXi’an 710072China Innovation Academy for Microsatellites Chinese Academy of SciencesShanghai 710699China School of Automation Beijing Institute of TechnologyBeijing 100081China Institute of Mechanics Chinese Academy of SciencesBeijing 710043China School of Automation Science and Electrical Engineering Beihang UniversityBeijing 100191China School of Automation Science and Engineering Xi’an Jiaotong UniversityXi’an 710049China

The Drag-Free and Attitude Control System(DFACS)is a critical platform for various space missions,including high precision satellite navigation,geoscience and gravity field measurement,and space scientific *** paper presents a comprehensive review of over sixty years of research on the design and dynamics model of ***,we examine the open literature on DFACS and its applications in Drag-Free missions,providing readers with necessary background information on the ***,we analyze the system configurations and main characteristics of different DFACSs,paying particular attention to the coupl.ng mechanism between the system configuration and dynamics ***,we summarize the dynamics model.ng methods and main dynamics models of DFACS from multiple perspectives,including common fundamentals and specific ***,we identify current chall.nges and technological difficulties in the system design and dynamics model.ng of DFACS,while suggesting potential avenues for future *** paper aims to provide readers with a comprehensive understanding of the state-of-the-art in DFACS research,as well as the future prospects and chall.nges in this field.

关键词： Drag-Free DFACS System Design Dynamics Model.ng Control design

Facile Semiconductor p-n Homojunction Nanowires with Strategic p-Type Doping Engineering Combined with Surface Reconstruction for Biosensing Applications

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Nano-Micro letters 2024年第10期16卷 15-30页

作者： liuan li Shi Fang Wei Chen Yueyue li Mohammad Fazel Vafadar Danhao Wang Yang Kang Xin liu Yuanmin luo Kun liang Yiping dang lei Zhao Songrui Zhao Zongzhi Yin Haiding Sun iGaN laboratory School of MicroelectronicsUniversity of Science and Technology of ChinaHefei 230026People's Republic of China Department of Obstetrics and Gynecology The First Affiliated Hospital of Anhui Medical UniversityNo 218 Jixi RoadHefei 230022People's Republic of China Department of Electrical and Computer Engineering McGill University3480 University StreetMontrealQC H3A 0E9Canada Union Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyNo 1277 Jiefang Ave.Wuhan 430022People's Republic of China

Photosensors with versatile functionalities have emerged as a cornerstone for breakthroughs in the future optoelectronic systems across a wide range of *** particular,emerging photoelectrochemical(PEC)-type devices have recently attracted extensive interest in liquid-based biosensing applications due to their natural electrolyte-assisted operating ***,a PEC-type photosensor was carefully designed and constructed by employing gallium nitride(GaN)p-n homojunction semiconductor nanowires on silicon,with the p-GaN segment strategically doped and then decorated with cobalt-nickel oxide(CoNiO_(x)).Essentially,the p-n homojunction configuration with facile p-doping engineering improves carrier separation efficiency and facilitates carrier transfer to the nanowire surface,while CoNiO_(x)decoration further boosts PEC reaction activity and carrier dynamics at the nanowire/electrolyte ***,the constructed photosensor achieves a high responsivity of 247.8 mA W^(-1)while simultaneously exhibiting excellent operating ***,based on the remarkable stability and high responsivity of the device,a glucose sensing system was established with a demonstration of glucose level determination in real human *** work offers a feasible and universal approach in the pursuit of high-performance bio-related sensing applications via a rational design of PEC devices in the form of nanostructured architecture with strategic doping engineering.

关键词： p-n GaN nanowires Strategic p-doping Surface decoration Photoelectrochemical sensor Glucose sensing