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武汉理工大学学报 2004年第2期26卷 87-89页

作者：饶文碧熊卉玥黄波武汉理工大学计算机科学与技术学院武汉430070

介绍了 PKI的公钥加密技术和数字证书技术、PKI的机构组成及其工作的流程。讨论了在实际应用中 ,如何结合会话密钥的使用 ,构造解析数字信封。

关键词： PKI 公钥加密数字证书

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Based on non-targeted metabolomics for differential components screening of Rosae Chinensis Flos and Rosae Rugosae Flos and their quality evaluation

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Traditional Medicine Research 2025年第2期10卷 1-15页

作者： Xu Liang Ni-hui Zhang Zhi-Lai Zhan Guang-Lu Chang Yan Gao Xia Li wen-Yuan Gao School of Pharmaceutical Science and Technology Faculty of MedicineTianjin UniversityTianjin 300193China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs China Academy of Chinese Medical SciencesBeijing 100700China Key Laboratory of Modern Chinese Medicine Resources Research Enterprises Tianjin 300402China

Background:Rosa chinensis *** Rosa rugosa *** not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional *** two plants have some differences in efficacy,but the flower buds are easily confused for similar *** addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal ***,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and yueji from different regions in China were collected to establish high-performance liquid chromatography ***,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large *** compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of yueji and ***:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the *** principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four *** least-squares discriminant analysis analysis showed that Meigui and yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavon

关键词： Rosa chinensis Jacq. Rosa rugosa Thunb. metabolomics chemometrics multiple component quantification quality evaluation

Effect of Post-weld Tempering on the Microstructure and Mechanical Properties in the Simulated HAZs of a High-Strength-High-Toughness Combination Marine Engineering Steel

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Acta Metallurgica Sinica(English Letters) 2020年第3期33卷 391-402页

作者： wen-Chao Dong Ming-yue wen hui-Yong Pang Shan-Ping Lu Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China Wuyang Iron and Steel Co.Ltd. Pingdingshan 462500China

The effects of tempering temperatures on the microstructure and mechanical properties of the simulated coarse-grain heataffected zone(CGHAZ) and inter-critical heat-affected zone(ICHAZ) were investigated for a high-strength-high-toughness combination marine engineering *** results demonstrate that the microstructure of the simulated CGHAZ and ICHAZ after tempering is characterized by tempering sorbites and coarse grain in the simulated *** tempering temperature increases,the tensile strength of the simulated CGHAZ and ICHAZ decreases and the Charpy absorbed energy of the simulated ICHAZ at-50℃increases remarkably,but the impact toughness of the simulated CGHAZ is not *** tempering at 550℃,the coarse flake carbides,which distribute at the prior austenite grain and martensite lath boundaries,deteriorate the impact toughness of the simulated *** the increase in tempering temperature,the morphology and the size of the carbides gradually change from coarse flake to fine granular,which is beneficial to the improvement of impact ***,the coarse-grain size of the simulated CGHAZ and the M23 C6-type carbide precipitated along the grain boundaries weakens the enhancing effect of carbides on impact toughness.

关键词： High-strength-high-toughness combination steel Post-weld heat treatment Heat-affected zones(HAZs) Carbides Impact toughness

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Analysis of the anti-T2DM components in dichloromethane fraction of Schisandra sphenanthera and its mechanism

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Traditional Medicine Research 2025年第1期10卷 27-43页

作者： Shi-Bo Feng Hai-hui Jiang hui-Li Kang Yi Jiang Hua-Wei Zhang Xiao-Mei Song Yu-Ze Li wen-Li Huang Dong-Dong Zhang Chong Deng School of Pharmacy Shaanxi University of Chinese MedicineXianyang 712046China School of Pharmacy and Shaanxi Qinling Application Development and Engineering Center of Chinese Herbal Medicine Shaanxi University of Chinese MedicineXianyang 712046China Key Laboratory for Research and Development of“Qin Medicine”of Shaanxi Administration of Traditional Chinese Medicine Xianyang 712046China Shaanxi Key Laboratory of Research and Application of“Taibai Qi Yao” Xianyang 712046China

Background:The type 2 diabetes mellitus(T2DM)pharmacodynamic study of various parts of Schisandra sphenanthera was conducted in the previous stage,and it was found that dichloromethane extracted part(SDP)had a significant hypoglycemic ***,the components of SDP were analyzed,and the specific mechanism of its anti-T2DM was ***:We used a high-fat,high-sugar diet in combination with streptozotocin to induce a T2DM rat model,and the model rats were divided into two groups according to body weight and blood ***,oral glucose tolerance test,fasting blood glucose,low density lipoprotein cholesterol,superoxide dismutase,insulin,glycated hemoglobin,total cholesterol,nonesterified free fatty acids,alanine aminotransferase,high-density lipoprotein cholesterol,aspartate aminotransferase,malondialdehyde,and glutathione peroxidase were measured,organ indices were calculated,and pathological sections of pancreas and liver were *** 16S rRNA V3–V4 region of intestinal flora was sequenced to explore the effect of SDP on biochemical indicators and intestinal *** on the above indicators,the anti-T2DM mechanism of SDP in Schisandra sphenanthera was ***:After six weeks of administration,the biochemical indices of diabetic rats were diminished compared to the control *** SDP could significantly increase the gut microbialα-diversity index,resulting in significant changes in the flora of T2DM rats,with increased richness and diversity,reduced harmful flora,and significantly back-regulated the levels of acetic acid,propionic acid,and butyric ***:SDP can improve the symptoms associated with elevated blood glucose,dyslipidemia,elevated fasting insulin levels,and damaged glucose tolerance in *** against T2DM may be through the control of intestinal flora to normalize and exert anti-diabetic effect;its main active components may be lignans and terpenoids.

关键词： Schisandra sphenanthera T2DM intestinal flora HPLC

Primary parenchymal squamous cell carcinoma of the kidney:A case report

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World Journal of Clinical Cases 2025年第4期13卷 34-40页

作者： Zhi-hui Zheng Bo Shao Chao-Min Xu Ke Wang Jia-Zhu wen Li-Kang Luo Jia-Cheng Guan Department of Ultrasound The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Radiology Shulan(Quzhou)HospitalQuzhou 324000Zhejiang ProvinceChina Department of Radiology The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Pathology The Second people’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina

BACKGROUND Primary squamous cell carcinoma(SCC)of the renal parenchyma is extremely rare,with only nine cases *** SUMMARY This study reports a 51-year-old man with primary SCC of the renal *** patient was admitted with recurrent dull pain and discomfort in the right lumbar region,which had worsened over 2 weeks,accompanied by painful gross *** antigen(SCCA)levels were elevated,and imaging revealed a renal mass with associated *** patient underwent laparoscopic unilateral nephrectomy and lymph node *** pathology confirmed highly differentiated SCC with necrosis in the right renal parenchyma,with negative renal pelvis and *** pathological stage was *** months after surgery,the tumor recurred with involvement of the liver,right psoas major muscle,and inferior vena *** patient refused chemotherapy and succumbed to the disease 6 months postoperatively due to disease *** We report a case of primary SCC of the renal parenchyma,a rare renal *** clinical symptoms,laboratory tests,and imaging findings are nonspecific,making accurate and timely diagnosis *** to the literature,for patients with renal calculi accompanied by a renal mass,elevated serum SCCA levels,and magnetic resonance imaging showing cystic or cystic-solid masses within the kidney with pseudocapsules and heterogeneous mild enhancement,the possibility of this disease should be considered.

关键词： Renal tumor Renal parenchyma Squamous cell carcinoma Renal calculi Computed tomography Case report

Moment Redistribution Effect of the Continuous Glass Fiber Reinforced Polymer-Concrete Composite Slabs Based on Static Loading Experiment

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Structural Durability & Health Monitoring 2025年第1期19卷 105-123页

作者： Zhao-Jun Zhang wen-Wei Wang Jing-Shui Zhen Bo-Cheng Li De-Cheng Cai Yang-Yang Du hui Huang Offshore Oil Engineering Co.Ltd. Tianjin300461China Department of Bridge Engineering School of TransportationSoutheast UniversityNanjing211189China

This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRP)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment *** experimental bending moment redistribution test was conducted on continuous GFRP-concrete composite slabs,and a calculation method based on the conjugate beam method was *** composite slabs were formed by combining GFRP profiles with a concrete layer and supported on steel beams to create two-span continuous composite slab *** methods,epoxy resin bonding,and stud connection,were used to connect the composite slabs with the steel *** experimental findings showed that the specimen connected with epoxy resin exhibited two moments redistribution phenomena during the loading process:concrete cracking and steel bar yielding at the internal *** contrast,the composite slab connected with steel beams by studs exhibited only one-moment redistribution phenomenon throughout the loading *** the concrete at the internal support cracked,the bending moment decreased in the internal support section and increased in the midspan *** the steel bars yielded,the bending moment further decreased in the internal support section and increased in the mid-span *** GFRP profiles do not experience cracking,there was no significant decrease in the bending moment of the mid-span *** test specimens experienced compressive failure of concrete at the mid-span *** results showed good agreement between the calculated and experimental values of bending moments in the mid-span section and internal support *** proposed model can effectively predict the moment redistribution behavior of continuous GFRP-concrete composite slabs.

关键词： Moment redistribution GFRP-concrete composite slabs bending moment experimental study analysis model

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婴幼儿CT增强扫描药物应用及观察

实用放射学杂志 2004年第6期20卷 556-557页

作者：张远芳刘国瑞方文辉郭岳霖汕头大学医学院第二附属医院放射科汕头大学医学院第二附属医院放射科广东汕头515041

目的　探讨婴幼儿CT增强扫描药物的应用及观察要点。方法　观察受检患儿 2 0 2例 ,药物非离子型造影剂优维显 ,镇静催眠药物 10 %水合氯醛、安定。剂量按公斤体重计算。结果　非离子型造影剂非绝对安全 ,少数患儿有副反应。碘过敏试验阳... 详细信息

目的　探讨婴幼儿CT增强扫描药物的应用及观察要点。方法　观察受检患儿 2 0 2例 ,药物非离子型造影剂优维显 ,镇静催眠药物 10 %水合氯醛、安定。剂量按公斤体重计算。结果　非离子型造影剂非绝对安全 ,少数患儿有副反应。碘过敏试验阳性 7例 ,占 3 .4% ,2 0 2例婴幼儿CT增强扫描取得满意效果。结论　在婴幼儿CT增强扫描中 ,正确使用造影剂 ,合理应用镇静催眠药物 ,根据不同年龄组采取相应护理对策 ,能取得良好的效果

关键词：婴幼儿增强优维显断层摄影,X线计算机

Synthesis,Crystal Structure and Antifungal Activity of New Furan-1,3,4-oxadiazole Carboxamide Derivatives

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Chinese Journal of Structural Chemistry 2022年第2期41卷 98-104,I0010页

作者： SUN yue YANG Zi-hui GU wen Jiangsu Provincial Key Lab for the Chemistry and Utilization of Agro-forest Biomass Jiangsu Key Lab of Biomass-based Green Fuels and ChemicalsCo-inovation Center for Efficient Processing and Utilization of Forest ProductsCollege of Chemical EngineeringNanjing Forestry UniversityNanjing 210031China

A series of novel furan-1,3,4-oxadiazole carboxamide derivatives (5a~5e) were designed,synthesized and characterized by spectroscopic methods including HR-MS,^(1)H-and ^(13)*** crystal structure of compound 5a was determined by single-crystal X-ray *** compound crystallizes in the triclinic system,space group P■ with a=4.7261(5),b=10.4672(11),c=14.5886(13)?,α=106.081(4)°,β=91.043(3)°,γ=99.456(4)°,Z=2,V=682.48(12)?^(3),M_(r)=348.16,D_(c)=1.694 Mg/m^(3),S=1.008,m=3.025 mm^(-1),F(000)=348,the final R=0.0775 and w R=0.2080 for 2774 observed reflections (I (29) 2σ(I)).There are two kinds of hydrogen bonds (N(3)–H(3A)×××N(2) and C(8)–H(8A)×××O(3)) present in its crystal *** preliminary antifungal assay showed that compounds 5b and 5c exhibited significant antifungal activities against several plant pathogenic fungi.

关键词： furan-1,3,4-oxadiazole carboxamide synthesis crystal structure antifungal activity

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Metal-organic framework[NH_(2)-MIL-53(Al)]functionalized TiO_(2)nanotube photoanodes for highly stable and efficient photoelectrochemical cathodic protection of nickel-coated Mg alloy

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Journal of Materials Science & Technology 2024年第15期182卷 67-78页

作者： Huan Yao Ruifeng Zhang Yu wen yue Liu Gang Yu Zhi-hui Xie Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province College of Chemistry and Chemical EngineeringChina West Normal UniversityNanchong 637002China School of Materials Science and Engineering Central South UniversityChangsha 410083China State Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan UniversityChangsha 410082China

Metal-organic framework[MOF,i.e.,NH_(2)-MIL-53(Al)]modified TiO_(2)(NMT)composite photoanodes were successfully prepared by hydrothermal synthesis and were used for the photoelectrochemical cathodic protection(PECCP)of nickel-plated magnesium alloy(Mg/Ni).Results showed that the synthesis tem-perature significantly impacted the morphology and PECCP performance of the NMT *** NMT@150 photoanode prepared at a reaction temperature of 150℃exhibited the best PECCP perfor-mance and produced a current density of 1980μA cm^(-2)under visible light irradiation,which was 19.8 times higher than that of a single TiO_(2)*** composite photoanode could polarize the open circuit potential of the coupled Mg/Ni electrode to-876 mV and remain relatively stable within 35 *** and EPR tests showed that a Z-scheme heterojunction was formed between the NH_(2)-MIL-53(Al)and TiO_(2)nanotubes,allowing the photogenerated electrons to accumulate mainly on the conduction band of NH_(2)-MIL-53(Al).The heterojunction greatly promoted the separation and transfer of photogenerated electron-hole in the NMT composite photoanode,significantly enhancing the PECCP performance for Mg/Ni.

关键词： Magnesium alloy Corrosion Nickel coating Electroless Photoelectrochemical cathodic protection

The Low-Carbon Transition of Energy Systems:A Bibliometric Review from an Engineering Management Perspective

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Engineering 2023年第10期29卷 147-158页

作者： Peng Zhou yue Lv wen wen School of Economics and Management China University of PetroleumQingdao 266580China

As a major solution to climate change,the low-carbon transition of energy systems has received growing attention in the past *** paper presents a bibliometric review of the literature on the low-carbon transition of energy systems from an engineering management ***,the definition and boundaries of the energy system transition are clarified,covering transformation of the energy structure,decarbonization of fossil fuel utilization,and improvement in energy ***,a systematic search of the related literature and a bibliometric analysis are conducted to reveal the research *** is found that the number of related publications has been growing exponentially during the past decade,with researchers from China,the United Kingdom,the United States,Germany,and the Netherlands comprising the majority of *** studies with interdisciplinary characteristics appear in journals focusing on energy engineering,environmental science,and social science related to energy *** major research themes are identified by clustering the existing literature:(1)low-carbon transition pathways with different spatiotemporal scales and transition constraints;(2)low-carbon technology diffusion with a focus on renewable energy technologies,pollution control technologies,and other technologies facilitating the energy transition;(3)infrastructure network planning for energy systems covering various sectors and regions;and(4)transition-driving mechanisms from the political,economic,social,and natural *** four topics play distinct but mutually supportive roles in facilitating the low-carbon transition of energy systems,and require more in-depth research on designing resilient low-carbon transition pathways with coordinated goals,promoting low-carbon technologies with cost-effective and reliable infrastructure network deployment,and balancing multi-level risks in various ***,business models,nongovernment actors,energy justi

关键词： Low-carbon transition Energy system Bibliometric review Systematic review