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Formulation of Determining the Gravity Potential Difference Using Ultra-High Precise Clocks via Optical Fiber Frequency Transfer Technique

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Journal of Earth Science 2019年第2期30卷 422-428页

作者： Ziyu shen wen-bin shen Zhao Peng Tao Liu Shougang Zhang Dingbo Chao School of Resource and Environment Hubei University of Science and Technology Time and Frequency Geodesy Research Center School of Geodesy and GeomaticsDepartment of GeophysicsKey Laboratory of Geospace Environment and Geodesy of the Ministry of EducationWuhan University State Key Laboratory of Information Engineering in Surveying Mapping and Remote SensingWuhan University National Time Service Center(NTSC) Chinese Academy of Sciences

Based on gravity frequency shift effect predicted by general relativity theory, this study discusses an approach for determining the gravity potential(geopotential) difference between arbitrary two points P and Q by remote comparison of two precise optical clocks via optical fiber frequency transfer. After synchronization, by measuring the signal's frequency shift based upon the comparison of bidirectional frequency signals from P and Q oscillators connected with two optical atomic clocks via remote optical fiber frequency transfer technique, the geopotential difference between the two points could be determined, and its accuracy depends on the stabilities of the optical clocks and the frequency transfer comparison technique. Due to the fact that the present stability of optical clocks achieves 1.6×10-18 and the present frequency transfer comparison via optical fiber provides stabilities as high as 10-19 level, this approach is prospective to determine geopotential difference with an equivalent accuracy of 1.5 cm. In addition, since points P and Q are quite arbitrary, this approach may provide an alternative way to determine the geopotential over a continent, and prospective potential to unify a regional height datum system.

关键词： gravity frequency shift optical fiber frequency transfer optical clock gravity potential

Determination of the orthometric height difference based on optical fiber frequency transfer technique

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Geodesy and Geodynamics 2021年第6期12卷 405-412页

作者： Anh The Hoang Ziyu shen wen bin shen Chenghui Cai Wei Xu An Ning Yifan Wu School of Geodesy and Geomatics Wuhan UniversityWuhan 430079China School of Resource Environmental Science and EngineeringHubei University of Science and TechnologyXianningHubeiChina School of Agriculture and Natural Resource Vinh UniversityVinh City 460000Viet Nam State Key Laboratory of Information Engineering in Surveying Mapping and Remote SensingWuhan UniversityWuhan 430079China Guangxi Key Laboratory of Spatial Information and Geomatics Guilin 541006China

The development of remote frequency transfer techniques,especially the appearance of optical clocks with unprecedented stability,has prompted geoscientists to study their applications in *** remote frequency transfer technique,by frequency comparison of two optical clocks at two points P and Q connected by optical fibers,one can measure the signal’s frequency shift between them,and the geopotential difference between them can be determined based on the gravity frequency shift *** the orthometric height of P,the orthometric height of Q can be *** the present stability of the optical clock has achieved 1×10^(-18) or better and comparing the frequency transfer via optical fiber provides stability at 10^(-19) level,the optical clock network enables determining the orthometric height at *** study provides a formulation to determine the height diffe rence at one-centimeter level between two points on the ground based on the optical fiber frequency transfer technique.

关键词： Optical fiber frequency transfer(OFFT) Optical fiber Frequency transfer Geopotential

Randomized clinical trial on seven-day-per-week continuous accelerated irradiation for patients with esophageal carcinoma: Preliminary report on tumor response and acute toxicity

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World Journal of Gastroenterology 2006年第43期12卷 7047-7050页

作者： Su-Ping Sun Ya-Zhou Liu Tao Ye wen Zhang wen-bin shen Jing-Lei Shi Hai-Ting Xu Wei-Dong Wang Department of Radiation Oncology ChangzhouSecond hospital-The Affiliated Hospital of Nanjing MedicalUniversity Changzhou 213003 Jiangsu Province China Department of Radiation Oncology Xuzhou Cancer Hospital Xuzhou 221005 Jiangsu Province China

AIM: Tumor response and normal tissue toxicity of seven-day-per-week continuous accelerated irradiation (CAIR) for patients with esophageal carcinoma were evaluated and compared to conventional irradiation (CR). METHODS: Sixty patients with squamous cell carcinoma of the esophagus were randomized into two groups: the CAIR group (30 patients) and the CR group (30 pa- tients). Patients in the CAIR group received radiotherapy (RT) with 2 Gy/fraction per day at 7 d/wk with a total dose of 50-70 Gy (average dose 64.2 Gy). The overall time of irradiation was 3.6-5.0 wk (average 4.6 wk). RT in the CR group was 2 Gy/fraction per day at 5 d/wk with a total dose of 40-70 Gy (average dose 61.7 Gy). The overall time of irradiation was 4.0-7.0 wk (average 6.4 wk). RESULTS: The data showed that the immediate tumor response to RT was better in the CAIR group than in the CR group. Efficiency rates (CR plus PR) were 82.8% (24/29) and 58.6% (17/29), respectively (P = 0.047). In both groups the incidences of esophagitis and tracheitis were insignificant (P = 0.376, 0.959), and no patient re- ceived toxicity that could not be tolerated. CONCLUSION: CAIR shortens overall treatment time and is well tolerated by patients. It may be superior to CR in enhancing the local response of tumor, but its remote effect for esophageal carcinoma awaits further follow-up.

关键词： Esophageal carcinoma Continuous acceler-ated irradiation Conventional irradiation Toxicity Over-all treatment time

A　NOVEL　CYCLODIMERIZATION　OF　α，β－　UNSATURATED　KETONES　PROMOTED　BY　LOW－VALENT　TITANIUM

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Chinese Chemical Letters 1995年第3期6卷 173-176页

作者： Long Hu ZHOU Gui Yuan DAI Da Qing SHI (Department of Chemistry,Xuzhou Teachers College, Xuzhou, 221009)wen bin shen (Physical & Chemical Center of Jiangsu Province,Nanjing, 210008) Xuzhou Teachers Coll Dept Chem Xuzhou 221009 Peoples R China Phys & Chem Ctr Jiangsu Prov Nanjing 210008 Peoples R China

Low - valent titanium reagent prepared from titanium tetrachloride and zinc in tetrahydrofuran has been used to promote a novel cyclodimerization of α,β-unsaturated ketones, leading to cyclopentanol derivatives (2 a...

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Endoscopic classification and pathological features of primary intestinal lymphangiectasia

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World Journal of Gastroenterology 2022年第22期28卷 2482-2493页

作者： Ming-Ming Meng Kui-Liang Liu Xin-Ying Xue Kun Hao Jian Dong Chun-Kai Yu Hong Liu Cang-Hai Wang Hui Su Wu Lin Guo-Jun Jiang Nan Wei Ren-Gui Wang wen-bin shen Jing Wu Department of Gastroenterology Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China Department of Respiratory and Critical Care Medicine Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China Departments of Lymphatic Surgery Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China Departments of Radiology Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China Departments of Pathology Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China

BACKGROUND The appearance of the intestinal mucosa during endoscopy varies among patients with primary intestinal lymphangiectasia(PIL).AIM To classify the endoscopic features of the intestinal mucosa in PIL under endoscopy,combine the patients’imaging and pathological characteristics of the patients,and explain their *** We retrospectively analyzed the endoscopic images of 123 patients with PIL who were treated at the hospital between January 1,2007 and December 31,*** compared and analyzed all endoscopic images,classified them into four types according to the endoscopic features of the intestinal mucosa,and analyzed the post-lymphographic computed tomography(PLCT)and pathological characteristics of each *** According to the endoscopic features of PIL in 123 patients observed during endoscopy,they were classified into four types:nodular-type,granular-type,vesicular-type,and *** showed diffuse thickening of the small intestinal wall,and no contrast agent was seen in the small intestinal wall and mesentery in the patients with nodular and granular *** agent was scattered in the small intestinal wall and mesentery in the patients with vesicular and edematous *** of the small intestinal mucosal pathology revealed that nodular-type and granulartype lymphangiectasia involved the small intestine mucosa in four layers,whereas ectasia of the vesicular-and edematous-type lymphatic vessels largely involved the lamina propria mucosae,submucosae,and muscular *** Endoscopic classification,combined with the patients’clinical manifestations and pathological examination results,is significant and very useful to clinicians when scoping patients with suspected PIL.

关键词： Primary intestinal lymphangiectasia Endoscopic features Post-lymphangiographic computed tomography Pathology

Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury

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Neural Regeneration Research 2025年第10期20卷 2955-2968页

作者： Wei Zhang Yubao Lu Ruoqi shen Yingjie Wu Chenrui Liu Xingxing Fang Liangming Zhang bin Liu Limin Rong Department of Spine Surgery The Third Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina National Medical Products Administration(NMPA)Key Laboratory for Quality Research and Evaluation of Cell Products GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Quality Control of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina Guangdong Provincial Center for Engineering and Technology Research of Minimally Invasive Spine Surgery GuangzhouGuangdong ProvinceChina

Microglia,the resident monocyte of the central nervous system,play a crucial role in the response to spinal cord ***,the precise mechanism remains *** investigate the molecular mechanisms by which microglia regulate the neuroinflammatory response to spinal cord injury,we performed single-cell RNA sequencing dataset analysis,focusing on changes in microglial *** found that the MG1 subpopulation emerged in the acute/subacute phase of spinal cord injury and expressed genes related to cell pyroptosis,sphingomyelin metabolism,and neuroinflammation at high ***,we established a mouse model of contusive injury and performed intrathecal injection of siRNA and molecular inhibitors to validate the role of ceramide synthase 5 in the neuroinflammatory responses and pyroptosis after spinal cord ***,we established a PC12-BV2 cell co-culture system and found that ceramide synthase 5 and pyroptosis-associated proteins were highly expressed to induce the apoptosis of neuron *** ceramide synthase 5 expression in a mouse model of spinal cord injury effectively reduced ***,ceramide synthase 5-induced pyroptosis was dependent on activation of the NLRP3 signaling *** ceramide synthase 5 expression in microglia in vivo reduced neuronal apoptosis and promoted recovery of neurological ***2g7 formed a“bridge”between sphingolipid metabolism and ceramide synthase 5-mediated cell death by inhibiting the NLRP3 signaling ***,these findings suggest that inhibiting ceramide synthase 5 expression in microglia after spinal cord injury effectively suppressed microglial pyroptosis mediated by NLRP3,thereby exerting neuroprotective effects.

关键词： ceramide synthase 5 gasdermin D microglia neuroinflammation NLRP3 nuclear factor kappa B Pla2g7 pyroptosis sphingomyelin metabolism spinal cord injury

Metal nanoparticles decorated CoFe-(oxy)hydroxysulfides nanosheets fabricated by a general strategy for electrocatalytic water splitting

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Journal of Energy Chemistry 2025年第1期100卷 26-38页

作者： Xiaodong Yang Haochen shen Xiaoming Xiao Zhichao Li Qi Zhou Wei Yang bin Jiang Yongli Sun Luhong Zhang Zhenhua Yan School of Chemical Engineering and Technology Tianjin University Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) Nankai University

This study presents a novel method to fabricate metal-decorated,sulfur-doped layered double hydroxides （M/SLDH） through spontaneous redox and sulfurization *** developed Ag/SLDH and Pt/SLDH catalysts with abundant heterogeneous interfaces and hierarchical nanostructures demonstrated outstanding oxygen evolution reaction （OER） and hydrogen evolution reaction （HER） performance,achieving low overpotentials of 212 and 35 mV at 10 mA cm-2in 1 M KOH,*** both anode and cathode in water splitting,they required only 1.47 V to reach 10 mA cm-2and exhibited high structural robustness,maintaining stability at 1000 mA cm-2for 300 ***-situ Raman analysis revealed that the synergistic effects of metal nanoparticles and S doping significantly promote the transformation into the S-Co1-xFexOOH layer,which serves as the active phase for water ***,ultraviolet photoelectron spectroscopy （UPS） and density functional theory （DFT） analyses indicated that incorporating metal nanoparticles and S doping increase electron density near the Fermi level and reduce reaction energy barriers,thus enhancing intrinsic OER and HER *** study provides a scalable strategy for synthesizing high-performance electrocatalysts for water splitting,with promising potential for broader applications.

关键词： Ultraviolet photoelectron spectroscopy

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镁合金直接化学镀镍的初始沉积机制

上海交通大学学报 2000年第12期34卷 1638-1640,1644页

作者：向阳辉胡文彬沈彬赵昌正丁文江上海交通大学金属基复合材料国家重点实验室上海200030

镁合金直接化学镀镍是其表面处理的一种方法 .通过 XPS、SAM和 SEM对化学镀镍的初始沉积机制进行了研究 .结果表明 ,镍的初始沉积是在活化中形成的氟化膜层下面 ,按照电化学的方式在第二相上形核的 .沉积过程与表面氧化物在镀液中的溶... 详细信息

镁合金直接化学镀镍是其表面处理的一种方法 .通过 XPS、SAM和 SEM对化学镀镍的初始沉积机制进行了研究 .结果表明 ,镍的初始沉积是在活化中形成的氟化膜层下面 ,按照电化学的方式在第二相上形核的 .沉积过程与表面氧化物在镀液中的溶解和基底与镍离子的置换反应有关 .

关键词：化学镀镍镁合金初始沉积

Merging bound states in the continuum in an open acoustic resonator

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 124-131页

作者： Lujun Huang bin Jia Artem S.Pilipchuk Sibo Huang Chen shen Almas F.Sadreev Yong Li Andrey E.Miroshnichenko School of Physics and Electronic Sciences East China Normal University Institute of Acoustics Tongji University L.V.Kirensky Institute of Physics Department of Mechanical Engineering Rowan University School of Engineering and Technology University of New South Wales at Canberra

Bound states in the continuum （BICs） are perfectly localized resonances despite embedding in the continuum ***,an isolated BIC is very sensitive to the structure ***,we report merging acoustic BICs in a single open resonator,robust against the structure *** find that both symmetry-protected BIC and Friedrich-Wintgen BIC are sustained in a single coupled waveguide-resonator *** varying the height and length of the resonator,these two BICs move toward each other and merge into a single one at a critical *** to an individual BIC,the merged BIC is robust against fabrication error because its Q-factor is proportional to ΔL-4,whereΔL embodies the structure *** essence of this extraordinary phenomenon is perfectly explained by the two-and three-level approximations of the effective nonHermitian ***,we present direct experimental demonstrations of the moving and merging of BICs in a coupled 3D waveguide-resonator,which are evidenced by the vanishing of the linewidth of Fano resonance in the transmission *** results may find exciting applications in designing high-quality acoustic sources,sensors and filters.

关键词： acoustic resonances bound state in the continuum high-Q resonances