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A Dietary Supplement Jinghuosu Ameliorates Reproductive Damage Induced by Tripterygium Glycosides

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Chinese Journal of Integrative Medicine 2024年第4期30卷 330-338页

作者： MA Jing sun Bo TE Li-ger HUANG xin ZUO xin HAN Xiao-ke WANG Shu-song Hebei Key Laboratory of Reproductive Medicine Hebei Institute of Reproductive HealthHebei Reproductive Health HospitalShijiazhuang(050071)China Graduate School of Hebei Medical University Shijiazhuang(050017)China School of Chemistry and Materials Science Hebei Normal UniversityShijiazhuang(050024)China xingtai Infertility Specialist Hospital XingtaiHebei Province(054000)China

Objective To determine the possible protective effects of Jinghuosu,a dietary supplement(DS),on tripterygium glycosides(TG)-induced reproductive system injury in rats and its underlying *** A reproductive damage model was established in rats by feeding of ***-eight male Sprague Dawley rats were randomly divided into 4 groups using a random number table(n=7 in each):control(C)group,model(M)group,DS group and L-carnitine(LC)*** in M,DS and LC groups received 40 mg/kg TGs *** from the 5th week,after administration of TGs for 4 h every day,rats in DS and LC groups were administered with 2.7 g/kg DS and 0.21 g/kg LC,respectively,for protective treatment over the next 4 *** in Group C continued to receive the control ***-eosin staining was used for histopathological analysis of rat testicular ***-linked immunosorbent assay was performed to measure alkaline phosphatase(ALP),lactate dehydrogenase,alcohol dehydrogenase,total antioxidant capacity(T-AOC),superoxide dismutase,glutathione peroxidase(GSH-Px),and malondialdehyde(MDA)*** assay was used to determine the serum testosterone *** real-time PCR and Western blotting were conducted to analyze the expression of genes and proteins related to the testosterone synthesis pathway and the nuclear factor erythroid 2-related factor 2/heme oxygenase 1 antioxidant *** Oral administration of TGs induced significant increases in the testicular levels of zinc transporter 1 and MDA(P<0.05).On the other hand,sperm concentration,sperm motility,and serum testosterone,serum zinc,testicular zinc,Zrt-,Irt-like protein 1,ALP,luteinizing hormone(LH)receptor,steroidogenic acute regulatory protein,Cytochrome P450 family 11 subfamily A member 1,3β-hydroxysteroid dehydrogenase 1 T-AOC,GSH-Px,nuclear factor erythroid 2-related factor 2,heme oxygenase-1 and NAD(P)H:quinone oxidoreductase 1 levels decreased following TG

关键词： dietary supplement Jinghuosu tripterygium glycosides reproductive damage infertility

Boosting the electrochromic properties by large V_(2)O_(5)nanobelts interlayer spacing tuned via PEDOT

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Chinese Chemical Letters 2024年第9期35卷 408-413页

作者： Haohao sun wenxuan Wang Yuli Xiong Zelang Jian wen Chen State Key Laboratory of Advanced Technology for Materials Synthesis and Processing School of Materials Science and EngineeringWuhan University of TechnologyWuhan 430070China Sanya Science and Education Innovation Park of Wuhan University of Technology Sanya 572000China

Vanadium pentoxide(V_(2)O_(5))with a layered structure is of great interest in the field of electrochromic(EC)due to its abundance of color ***,there are still a series of problems such as slow ion diffusion,poor electronic conductivity and cyclic stability in the reaction ***,we successfully prepared a stable and fast multi-color electrochromic material V_(2)O_(5)-PEDOT by a simple“one-pot”*** layer space of V_(2)O_(5)could be tuned by 3,4-ethylenedioxythiophene(named V_(2)O_(5)-PEDOT)during the dissolution and recrystallization of vanadium *** expanded layer spacing facilitates rapid ion insertion and *** serves as an internal conductive pillar to improve the overall conductivity of the *** obtained intercrossing structure of the nanobelts shortens the ion diffusion distance and ensures electrolyte *** V_(2)O_(5)-PEDOT exhibits the fast response time(1.1 s for coloration and 3.5 s for bleaching at 422 nm),high optical contrast(ΔT=45%at 422 nm andΔT=35.2%at 1000 nm),great coloration efficiency(CE=97.1 cm2/C),and high cyclic stability(86%preserved after 3000 cycles).The electrochromic devices(ECD)were successfully assembled by using V_(2)O_(5)-PEDOT films as ion storage layers and electrochromic layers,demonstrating remarkable performance.

关键词： Vanadium oxide PEDOT Nanobelts Interlayer spacing Electrochromic

Large-field objective lens for multi-wavelength microscopy at mesoscale and submicron resolution

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Opto-Electronic Advances 2024年第6期7卷 41-56页

作者： xin Xu Qin Luo Jixiang Wang Yahui Song Hong Ye xin Zhang Yi He Minxuan sun Ruobing Zhang Guohua Shi School of Biomedical Engineering(Suzhou) Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230026China Jiangsu Key Laboratory of Medical Optics Suzhou Institute of Biomedical Engineering and TechnologyChinese Academy of ScienceSuzhou 215163China

Conventional microscopes designed for submicron resolution in biological research are hindered by a limited field of view,typically around 1 *** restriction poses a challenge when attempting to simultaneously analyze various parts of a sample,such as different brain *** addition,conventional objective lenses struggle to perform consistently across the required range of wavelengths for brain imaging in *** we present a novel mesoscopic objective lens with an impressive field of view of 8 mm,a numerical aperture of 0.5,and a working wavelength range from 400 to 1000 *** achieved a resolution of 0.74μm in fluorescent beads *** versatility of this lens was further demonstrated through high-quality images of mouse brain and kidney sections in a wide-field imaging system,a confocal laser scanning system,and a two-photon imaging *** mesoscopic objective lens holds immense promise for advancing multi-wavelength imaging of large fields of view at high resolution.

关键词： mesoscopic objective lens large field-of-view high resolution multi-wavelength wide-field microscopy confocal laser scanning microscopy

Thermal-force control ability under variation of electromagnetic stick structure parameters in RPECT

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Journal of Iron and Steel Research International 2024年第1期31卷 224-236页

作者： Ting-song Yang wen-quan sun Feng-shan Du An-rui He Quan Yang National Engineering Research Center of Advanced Rolling and Intelligent Manufacturing University of Science and Technology BeijingBeijing100083China Institute of Engineering and Technology University of Science and Technology BeijingBeijing100083China College of Mechanical Engineering Yanshan UniversityQinhuangdao066004HebeiChina

Thermal-force driving of roll profile electromagnetic control technology(RPECT),which can be used to adjust the roll profile,can be affected by the sequential temperature rise between the electromagnetic stick(ES)and electromagnetic control *** to the limited space of ES and induction coil,the cross-sectional area of induction coil can be inevitably affected by changing the size of the ES induction zone,which can further change the energy input under the same electromagnetic parameters,the temperature rising effect and the bulging *** investigate this phenomenon,the effects of the radius of the induction zone on the thermal-force contribution ratio,the heating ability of ES and the temperature distribution were analyzed through an electromagnetic-thermal-structural finite element *** ensure that the results are applicable to RPECT,the thermal energy conversion ability and thermal-force roll crown control ability under different lengths of the induction zone were *** was found that whether the current density regulation mode or the current frequency regulation mode is adopted,the cases with 20 or 25 mm radius of the induction zone have the great thermal energy conversion ability and the good thermal-force roll crown control *** reasonable adjustment of the length of the induction zone can reduce the radius required for the maximum energy efficiency *** with the results of the simulation analysis,the optimization of ES based on the control ability maximization requirement is achieved,which provides the base for the design and configuration of ES in RPECT.

关键词： Roll profile electromagnetic control technology Electromagnetic stick Electromagnetic control roll Induction area Thermal-force driving

An effective strategy for dendrite free Li metal anodes:Nickel foam decorated with high lattice-matching CoN and CoF_(2) nanosheets for dense deposition

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Nano Research 2024年第5期17卷 4069-4078页

作者： wenlong Liu Jianzong Man Xiaodong sun Ning Zhang Yehong Du Kun Liu Zhongsheng wen Song Li Juncai sun Institute of Materials and Technology Dalian Maritime UniversityDalian 116026China Shandong Provinvial Key Laboratory of Chemical Energy Storage and Novel Cell Technology and School of Chemistry and Chemical enginneringLiaocheng UniversityLiaocheng 252000China Department of Public Security Management Liaoning Police CollegeDalian 116036China

The notorious dendrite and infinite volume change seriously restrict the advancement of lithium metal anodes(LMAs),during the long-term process of stripping/***,the nanosheets of metal fluoride(CoF_(2))and metal nitride(CoN)with magnificent lithiophilicity on the nickel(Ni)foam are designed as the“regulator”to uniform the Li plating and build stronger solid electrolyte interface(SEI)layer for dendrite free *** Ni foam offers abundant space to receive deposited Li *** CoN nanosheets can guarantee the fast transfer of electrons,which provides a stable interface of Li^(+)***,the nanosheet structure with lithiophilicity would accelerate the move of Li+and decrease the nucleation barrier,due to the high lattice-matching of Li and ***,the CoF_(2) could increase the content of F(LiF)in the SEI layer,which enhances the strength and avoids the destruction of SEI *** the cooperation of CoN and CoF_(2),the composited anode(Li/NF@CNCF)exhibits ultra-long cycle performance(more than 1200 h)and fantastic structure stability at 1 mA·cm^(-2) with 1 mAh·cm^(-2).Based on the LiFePO_(4) and Li/NF@CNCF,the full cells deliver excellent specifical capacity and steady coulombic *** strategy contributes an effective approach to alleviate the issues of lithium metal anodes in the field of LMAs.

关键词： CoN and CoF_(2) lattice-matching nanosheet lithiophilicity lithium metal anodes

Broadband and fabrication-tolerant 3-dB couplers with topological valley edge modes

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Light(Science & Applications) 2024年第8期13卷 1623-1630页

作者： Guo-Jing Tang Xiao-Dong Chen Lu sun Chao-Heng Guo Meng-Yu Li Zhong-Tao Tian Hou-Hong Chen Hong-Wei Wang Qi-Yao sun Ying-Di Pan xin-Tao He Yi-Kai Su Jian-wen Dong School of Physics&State Key Laboratory of Optoelectronic Materials and Technologies Sun Yat-sen UniversityGuangzhou 510275China State Key Laboratory of Advanced Optical Communication Systems and Networks Department of Electronic EngineeringShanghai Jiao Tong UniversityShanghai 200240China

3-dB couplers,which are commonly used in photonic integrated circuits for on-chip information processing,precision measurement,and quantum computing,face challenges in achieving robust performance due to their limited 3-dB bandwidths and sensitivity to fabrication *** address this,we introduce topological physics to nanophotonics,developing a framework for topological 3-dB *** couplers exhibit broad working wavelength range and robustness against fabrication dimensional *** leveraging valley-Hall topology and mirror symmetry,the photonic-crystal-slab couplers achieve ideal 3-dB splitting characterized by a wavelength-insensitive scattering *** analysis confirms the superiority on broad bandwidth of 48 nm and robust splitting against dimensional errors of 20 *** further propose a topological interferometer for on-chip distance measurement,which also exhibits robustness against dimensional *** extension of topological principles to the fields of interferometers,may open up new possibilities for constructing robust wavelength division multiplexing,temperature-drift-insensitive sensing,and optical coherence tomography applications.

关键词： topological splitting insensitive

High-power,electrically-driven continuous-wave 1.55-μm Si-based multi-quantum well lasers with a wide operating temperature range grown on wafer-scale InP-on-Si(100)heterogeneous substrate

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Light(Science & Applications) 2024年第8期13卷 1512-1523页

作者： Jialiang sun Jiajie Lin Min Zhou Jianjun Zhang Huiyun Liu Tiangui You xin Ou National Key Laboratory of Materials for Integrated Circuits Shanghai Institute of Microsystem and Information TechnologyCASShanghai 200050China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences100049 BeijingChina College of Information Science and Engineering Jiaxing UniversityJiaxing 314001China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of Sciences100190 BeijingChina Department of Electronic and Electrical Engineering University College LondonLondon WC1E 7JEUK

A reliable,efficient and electrically-pumped Si-based laser is considered as the main challenge to achieve the integration of all key building blocks with silicon *** the impressive advances that have been made in developing 1.3-μm Si-based quantum dot(QD)lasers,extending the wavelength window to the widely used 1.55-μm telecommunication region remains *** this study,we develop a novel photonic integration method of epitaxial growth of III-V on a wafer-scale InP-on-Si(100)(InPOS)heterogeneous substrate fabricated by the ion-cutting technique to realize integrated lasers on Si *** ion-cutting plus epitaxial growth approach decouples the correlated root causes of many detrimental dislocations during heteroepitaxial growth,namely lattice and domain *** this approach,we achieved state-of-the-art performance of the electrically-pumped,continuouswave(CW)1.55-μm Si-based laser with a room-temperature threshold current density of 0.65 kA/cm^(-2),and output power exceeding 155mW per facet without facet coating in CW *** lasing at 120℃ and pulsed lasing at over 130℃ were *** generic approach is also applied to other material systems to provide better performance and more functionalities for photonics and microelectronics.

关键词： pumped power quantum

Photo-Responsive Carbon Capture over Metalloporphyrin-C_(60) Metal-Organic Frameworks via Charge-Transfer

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Research 2024年第3期2023卷 233-241页

作者： Shi-Chao Qi Zhen sun Zhi-Hui Yang Yun-Jie Zhao Jia-xin Li Xiao-Qin Liu Lin-Bing sun State Key Laboratory of Materials-Oriented Chemical Engineering Jiangsu National Synergetic Innovation Center for Advanced Materials(SICAM)College of Chemical EngineeringNanjing Tech UniversityNanjing 211816China.

Great efforts have been devoted to the study of photo-responsive adsorption,but its current methodology largely depends on the well-defined photochromic units and their photo-driven molecular ***,a methodology to fabricate nondeforming photo-responsive sorbents is successfully *** C_(60)-fullerene doping in metalloporphyrin metal-organic frameworks(PCN-M,M=Fe,Co,or Ni)and intensively interacting with the metalloporphyrin sites,effective charge-transfer can be achieved over the metalloporphyrin-C_(60) architectures once excited by the light at 350 to 780 *** electron density distribution and the resultant adsorption activity are thus changed by excited states,which are also stable enough to meet the timescale of microscopic adsorption *** charge-transfer over Co(II)-porphyrin-C_(60) is proved to be more efficient than the Fe(II)-and Ni(II)-porphyrin-C_(60) sites,as well as than all the metalloporphyrin sites,so the CO_(2) adsorption capacity(CAC;at 0°C and 1 bar)over the C_(60)-doped PCN-Co can be largely improved from 2.05 mmol g^(−1) in the darkness to 2.69 mmol g−1 with light,increased by 31%,in contrast to photo-irresponsive CAC over all C_(60)-undoped PCN-M sorbents and only the photo-loss CAC over C_(60).

关键词： porphyrin adsorption excited

Paradigm for Determining the Optimal Ultradeep and Superthick Saline Aquifer for High-TDS Mine Water Geological Storage

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Acta Geologica Sinica(English Edition) 2024年第3期98卷 771-785页

作者： LI xin CHEN Ge XU Zhimin LIU Qi CHEN Tianci sun Yajun School of Resources and Geosciences China University of Mining and TechnologyXuzhouJiangsu 221116China National Professional Central Laboratory of Basic Research on Mine Water Disaster Prevention and Control Technology XuzhouJiangsu 221116China

Saline aquifers are the most popular waste and CO_(2)injection and storage reservoirs *** project proposes that several optimal injection positions should be investigated as hydraulic pressure-focused positions,in order to relieve the high demands of pump *** comprehensive indices(F_(i))representing the injectivity of different burial depths were obtained by using information entropy,based on the mercury injection experimental data of 13 rock *** results demonstrated that the burial depths of No.4,No.1 and No.2 in the Liujiagou Formation were the most suitable positions for hydraulic focused injection,which means the upper 30 m thickness could be regarded as the hydraulic focused range in the saline aquifer with an average thickness of 400 *** addition,some laboratory experiments and in situ tests were carried out for the purpose of certifying and analyzing results,including SEM,XRD,brittleness index and *** results suggested that the rock samples at the No.4,No.1 and No.2 burial depth ranges have loose microstructure,weak cementation,as well as dual pores and *** lithology is mainly quartz and feldspar,but the clay mineral content is high(10%-25%),which is positive for *** lithology is suitable for hydraulic fracturing to form extended cracks and micro-fissures during high-TDS(total dissolved solids)mine water injection,because of the high brittleness ***,a theoretical and technical framework for high-TDS mine water injection was established,based on operating pilot *** theoretical defects and drawbacks learned from the field practices were summarized and solutions *** research in this study could provide guidance and a paradigm for the inexpensive treatment of high-TDS mine water by injection and storage.

关键词： ultradeep Liujiagou Formation high-TDS mine water optimal hydraulic injection positions information entropy reservoir spatial characteristics