检索结果-南通市图书馆

Carbon Catabolite Repressor UvCreA is Required for Development and Pathogenicity in Ustilaginoidea virens

在线全文

学校读者我要写书评

暂无评论

Rice science 2024年第2期31卷 203-214,I0029-I0031页

作者： XIE Shuwei SHI Huanbin wen Hui LIU Zhiquan QIU Jiehua jiang Nan KOU Yanjun State Key Laboratory of Rice Biology and Breeding China National Rice Research InstituteHangzhou 311400China

The rice false smut disease, caused by Ustilaginoidea virens, has emerged as a significantglobal threat to rice production. The mechanism of carbon catabolite repression plays a crucial role in theefficient utilization of carbon nutrients and enzyme regulation in the presence of complex nutritionalconditions. Although significant progress has been made in understanding carbon catabolite repression infungi such as Aspergillus nidulans and Magnaporthe oryzae, its role in U. virens remains unclear. Toaddress this knowledge gap, we identified UvCreA, a pivotal component of carbon catabolite repression,in U. virens. Our investigation revealed that UvCreA localized to the nucleus. Deletion of UvCreA resultedin decreased growth and pathogenicity in U. virens. Through RNA-seq analysis, it was found that theknockout of UvCreA led to the up-regulation of 514 genes and down-regulation of 640 genes. Moreover,UvCreA was found to be involved in the transcriptional regulation of pathogenic genes and genesassociated with carbon metabolism in U. virens. In summary, our findings indicated that UvCreA isimportant in fungal development, virulence, and the utilization of carbon sources through transcriptionalregulation, thus making it a critical element of carbon catabolite repression.

关键词： Ustilaginoidea virens virulence carbon catabolite repression Oryza sativa rice false smut

Preparation and Tribological Properties of Onion-like Carbon/Waterborne Polyurethane Coatings

在线全文

学校读者我要写书评

暂无评论

China Petroleum Processing & Petrochemical Technology 2024年第2期26卷 108-120页

作者： Fei Xingpeng jiang Wuhao wen Maosheng Xu Yong Hu Kunhong Hu Enzhu Department of Energy Materials and Chemical Engineering Hefei UniversityHefei 230601China Anhui Province Key Laboratory of Critical Friction Pair for Advanced Equipment Hefei 230088China

Rice husk powder was used as a carbon source in a high-temperature carbonization reaction for the production of rice husk ash(RHA).Under the catalysis of ferric nitrate,onion-like carbon(OLC)nanomaterial with a particle size of approximately 200 nm was successfully prepared and incorporated into waterborne polyurethane(WPU).The tribological properties of the coatings were determined using a controlled-atmosphere tribometer(WMT-2E)under dry-friction *** the friction test,the friction mechanism was investigated by characterizing the abrasive spot surfaces of the test samples using 3D laser microscopy and scanning electron microscopy/energy dispersive *** final results demonstrated that the thermal stability of WPU composite coatings containing various concentrations of OLC nanoparticles was significantly enhanced,binding forces between coatings and steel sheets increased,and hardness improved compared to pure WPU *** tests revealed a notable enhancement in the anti-wear properties of WPU coatings due to the presence of OLC ***,the wear rate of the 1.5%OLC/WPU coating was reduced by 45.3%.The coating’s anti-wear mechanism was attributed to the improvement in the mechanical properties of WPU due to OLC,as well as OLC’s participation in the formation of a transfer film under induced friction,which protected the matrix.

关键词： biomass carbon onion-like carbon waterborne polyurethane wear transfer films

Current and future research directions in cellular metabolism of colorectal cancer:A bibliometric analysis

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第8期16卷 3732-3737页

作者： Bo-wen jiang Xiu-Hua Zhang Rui Ma wen-Yu Luan Yan-Dong Miao Department of Emergency Yantai Affiliated Hospital of Binzhou Medical UniversityThe Second Medical College of Binzhou Medical UniversityYantai 264100Shandong ProvinceChina Department of Oncology Laiyang Central HospitalYantai 265200Shandong ProvinceChina Department of Cancer Center Yantai Affiliated Hospital of Binzhou Medical UniversityThe Second Medical College of Binzhou Medical UniversityYantai 264100Shandong ProvinceChina

The primary aim of this study was to analyze the evolving trends and key focal points in research on cellular metabolism of colorectal cancer(CRC).Relevant publications on cellular metabolism in CRC were sourced from the Science Citation Index Expanded within the Web of Science Core Collection *** analysis and visualization were conducted using VOSviewer(version 1.6.18)software and CiteSpace 6.1.R6(64-bit)Basic.A comprehensive compilation of 4722 English-language publications,covering the period from January 1,1991 to December 31,2022,was carefully identified and included in the *** the authors,“Ogino,Shuji”contributed the most publications in this field,while“Giovannucci,E”garnered the highest number of *** journal“Cancer Research”ranked first in both publication volume and ***,“Shanghai Jiao Tong University”emerged as the top contributor in terms of published articles,while“Harvard University”led in citation *** country-based analysis,the United States held the top position in both publication output and citations,closely followed by *** increasing recognition of the significance of cellular metabolism in CRC underscores its potential for novel therapeutic approaches aimed at improving CRC management and prognosis.

关键词： Cellular metabolism Colorectal cancer Bibliometric analysis Metabolic reprogramming Cellular metabolism

Potential therapeutic role of spermine via Rac1 in osteoporosis:Insights from zebrafish and mice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Zoological Research 2024年第2期45卷 367-380页

作者： Rui-Xue jiang Nan Hu Yu-Wei Deng Long-Wei Hu Hao Gu Nan Luo Jin wen Xin-Quan jiang Department of Prosthodontics Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China College of Stomatology Shanghai Jiao Tong UniversityNational Center for StomatologyNational Clinical Research Center for Oral DiseasesShanghai Key Laboratory of StomatologyShanghai Research Institute of StomatologyShanghai Engineering Research Center of Advanced Dental Technology and MaterialsShanghai 200125China Department of Endodontics Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai Jiao Tong UniversityShanghai 200011China Department of Oral and Maxillofacial-Head and Neck Oncology Shanghai Ninth People’s HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200011China Department of Preventive Dentistry Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai Jiao Tong UniversityShanghai 200011China

Osteoporosis(OP)is a prevalent metabolic bone *** drug therapy is essential to prevent bone loss in osteoporotic patients,current treatments are limited by side effects and high costs,necessitating the development of more effective and safer targeted *** a zebrafish(Danio rerio)larval model of osteoporosis,we explored the influence of the metabolite spermine on bone *** showed that spermine exhibited dual activity in osteoporotic zebrafish larvae by increasing bone formation and decreasing bone *** not only demonstrated excellent biosafety but also mitigated prednisolone-induced embryonic neurotoxicity and ***,spermine showcased protective attributes in the nervous systems of both zebrafish embryos and *** the molecular level,Rac1 was identified as playing a pivotal role in mediating the antiosteoporotic effects of spermine,with P53 potentially acting downstream of *** findings were confirmed using mouse(Mus musculus)models,in which spermine not only ameliorated osteoporosis but also promoted bone formation and mineralization under healthy conditions,suggesting strong potential as a bonestrengthening *** study underscores the beneficial role of spermine in osteoporotic bone homeostasis and skeletal system development,highlighting pivotal molecular *** their efficacy and safety,human endogenous metabolites like spermine are promising candidates for new anti-osteoporotic drug development and daily bone-fortifying agents.

关键词： Osteoporosis Spermine Rac1 Zebrafish Mice

The hard X-ray nanoprobe beamline at the SSRF

在线全文

学校读者我要写书评

暂无评论

Nuclear Science and Techniques 2024年第7期35卷 79-88页

作者： Yan He Hui jiang Dong-Xu Liang Zhi-Sen jiang Huai-Na Yu Hua Wang Cheng-wen Mao Jia-Nan Xie Ai-Guo Li Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai201210China

The hard X-ray nanoprobe beamline BL13U is a phase-Ⅱ beamline project at the Shanghai Synchrotron Radiation *** beamline aims to enable comprehensive experiments at high spatial resolutions ranging from 50 to 10 nm. The X-ray energy range of the beamline, 5–25 keV, can detect most elements in the periodic table. Two operating modes were designed to accommodate the experimental requirements of high-energy resolution or high photon flux, respectively. X-ray nanofluorescence, nanodiffraction, and coherent diffraction imaging are developed as the main experimental techniques for BL13U. This paper describes the beamline optics, end station configurations, experimental methods under development, and preliminary test results. This comprehensive overview aims to provide a clear understanding of the beamline capabilities and potential applications.

关键词： Shanghai synchrotron radiation facility Hard X-ray nanoprobe X-ray nanofocusing

Quantitative prediction model for the depth limit of oil accumulation in the deep carbonate rocks:A case study of Lower Ordovician in Tazhong area of Tarim Basin

在线全文

学校读者我要写书评

暂无评论

Petroleum Science 2024年第1期21卷 115-124页

作者： wen-Yang Wang Xiong-Qi Pang Ya-Ping Wang Zhang-Xin Chen Fu-Jie jiang Ying Chen State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing100029China State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing102249China College of Geosciences China University of Petroleum(Beijing)Beijing102249China Research Institute of Exploration and Development PetroChina Southwest Oil&Gas Field CompanyChengdu610041SichuanChina Chemical and Petroleum Engineering Schulich School of EngineeringUniversity of CalgaryCalgaryT2N 1N4Canada

With continuous hydrocarbon exploration extending to deeper basins,the deepest industrial oil accumulation was discovered below 8,200 m,revealing a new exploration ***,the extent to which oil exploration can be extended,and the prediction of the depth limit of oil accumulation(DLOA),are issues that have attracted significant attention in petroleum *** it is difficult to characterize the evolution of the physical properties of the marine carbonate reservoir with burial depth,and the deepest drilling still cannot reach the ***,the DLOA cannot be predicted by directly establishing the relationship between the ratio of drilling to the dry layer and the *** this study,by establishing the relationships between the porosity and the depth and dry layer ratio of the carbonate reservoir,the relationships between the depth and dry layer ratio were obtained *** depth corresponding to a dry layer ratio of 100%is the *** on this,a quantitative prediction model for the DLOA was finally *** results indicate that the porosity of the carbonate reservoir,Lower Ordovician in Tazhong area of Tarim Basin,tends to decrease with burial depth,and manifests as an overall low porosity reservoir in deep *** critical porosity of the DLOA was 1.8%,which is the critical geological condition corresponding to a 100%dry layer ratio encountered in the *** depth of the DLOA was 9,000 *** study provides a new method for DLOA prediction that is beneficial for a deeper understanding of oil accumulation,and is of great importance for scientific guidance on deep oil drilling.

关键词： Deep layer Tarim Basin Hydrocarbon accumulation Depth limit of oil accumulation Prediction model

Single-source-precursor synthesis and air-plasma ablation behavior of(Ti,Zr,Hf)C/SiC ceramic nanocomposites at 2200℃

在线全文

学校读者我要写书评

暂无评论

Journal of Advanced Ceramics 2024年第7期13卷 1043-1059页

作者： Li Lu Qingbo wen Jinrun Hu Tianxing jiang Xiangchao Ren Yalei Wang Yi Zeng Xiang Xiong State Key Laboratory of Powder Metallurgy Central South UniversityChangsha 410083China

Dense monolithic(Ti,Zr,Hf)C/SiC ceramic nanocomposites with four different molar ratios of metallic elements in the(Ti,Zr,Hf)C phase(i.e.,Ti:Zr:Hf=1:1:1,2:3:5,2:3:3,and 1:2:1)were prepared upon pyrolysis of novel(Ti,Zr,Hf)-containing single-source precursors(SSPs),followed by spark plasma sintering(SPS).A thorough characterization was conducted to elucidate the synthesis of the SSPs,polymer-to-ceramic transformation,chemical/phase compositions,and microstructure of the SiTiZrHfC-based *** results revealed the feasibility of synthesizing nanocomposites with high(Ti,Zr,Hf)C contents using the SSP *** nanocomposites were characterized by a unique microstructure with in situ generated(Ti,Zr,Hf)C@C core-shell nanoparticles homogeneously mixed withβ-*** ablation behavior of the nanocomposites was evaluated on an air-plasma device for 60 ***,the nanocomposites exhibited excellent ablation resistance,and the lowest linear ablation rate reached−0.58μm/s at 2200°***,the ablation resistance can be dramatically improved by precisely tailoring the atomic ratios of metal elements within the(Ti,Zr,Hf)C phase via the molecular design of the *** formation of a multiple-oxide layer with both a high-meltingpoint phase((Ti,Zr,Hf)O_(2))and low-melting-point phases((Zr,Hf)TiO_(4))and glassy SiO_(2),as well as their structure,played a critical role in the enhanced ablation *** uniform distribution of the high-melting-point(Ti,Zr,Hf)O_(2)nano/microparticles throughout the glassy SiO_(2)matrix significantly enhanced the viscosity and stability of the oxide layer by the pinning effect,offering superior protection against the ingress of oxygen atoms and excellent resistance to mechanical erosion.

关键词： ultrahigh-temperature ceramics(UHTCs) multicomponent carbide nanocomposites ablation behavior multiple oxides

Interpenetrating network-reinforced gel polymer electrolyte for ultra-stable lithium−iodine batteries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Carbon Energy 2024年第6期6卷 234-247页

作者： Ying jiang Peng Huang Minman Tong Bingxin Qi Tao Sun Zhongyun Xian wen Yan Chao Lai School of Chemistry and Materials Science Jiangsu Normal UniversityXuzhouJiangsuChina

Li-I_(2) batteries have attracted much interest due to their high capacity,exceptional rate performance,and low *** so,the problems of unstable Li anode/electrolyte interface and severe polyiodide shuttle in Li-I_(2) batteries need to be ***,the interfacial reactions on the Li anode and I_(2) cathode have been effectively optimized by employing a well-designed gel polymer electrolyte strengthened by cross-linked Ti-O/Si-O(GPETS).The interpenetrating network-reinforced GPETS with high ionic conductivity(1.88×10^(-3)S cm^(-1)at 25℃)and high mechanical strength endows uniform Li deposition/stripping over 1800 h(at 1.0mA cm^(-2),with a plating capacity of 3.0mAh cm^(-2)).Moreover,the GPETS abundant in surface hydroxyls is capable of capturing soluble polyiodides at the interface and accelerating their conversion kinetics,thus synergistically mitigating the shuttle *** from these properties,the use of GPETS results in a high capacity of 207 mAh g^(-1)(1 C)and an ultra-low fading rate of 0.013%per cycle over 2000 cycles(5 C).The current study provides new insights into advanced electrolytes for Li-I_(2) batteries.

关键词： electrode/electrolyte interface gel polymer electrolytes lithium dendrites lithium−iodine batteries polyiodide shuttle

A Model for Detecting Fake News by Integrating Domain-Specific Emotional and Semantic Features

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第8期80卷 2161-2179页

作者： wen jiang Mingshu Zhang Xu’an Wang Wei Bin Xiong Zhang Kelan Ren Facheng Yan College of Cryptography Engineering Engineering University of People’s Armed PoliceXi’an710086China Key Laboratory of Network and Information Security Engineering University of People’s Armed PoliceXi’an710086China Key Laboratory of CTC&Information Engineering Engineering University of People’s Armed PoliceMinistry of EducationXi’an710086China

With the rapid spread of Internet information and the spread of fake news,the detection of fake news becomes more and more *** detection methods often rely on a single emotional or semantic feature to identify fake news,but these methods have limitations when dealing with news in specific *** order to solve the problem of weak feature correlation between data from different domains,a model for detecting fake news by integrating domain-specific emotional and semantic features is *** method makes full use of the attention mechanism,grasps the correlation between different features,and effectively improves the effect of feature *** algorithm first extracts the semantic features of news text through the Bi-LSTM(Bidirectional Long Short-Term Memory)layer to capture the contextual relevance of news ***-BiLSTM is then used to extract emotional features and predict the probability of positive and negative emotions in the *** then uses domain features as an enhancement feature and attention mechanism to fully capture more fine-grained emotional features associated with that ***,the fusion features are taken as the input of the fake news detection classifier,combined with the multi-task representation of information,and the MLP and Softmax functions are used for *** experimental results show that on the Chinese dataset Weibo21,the F1 value of this model is 0.958,4.9% higher than that of the sub-optimal model;on the English dataset FakeNewsNet,the F1 value of the detection result of this model is 0.845,1.8% higher than that of the sub-optimal model,which is advanced and feasible.

关键词： Fake news detection domain-related emotional features semantic features feature fusion