检索结果-南通市图书馆

Chinese Journal of Polymer Science 2024年第6期42卷 851-863页

作者： Yan-jiang Li Meng-Long Hu Jun-wen Zhang Qiang Fu Jie Zhang College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu610065China

To enhance the mechanical properties of polypropylene random copolymer(PPR),polystyrene(PS)with four different contents were added to the PPR matrix through melt ***,using the Multi-Flow Vibration Injection Molding(MFVIM)technology,PPR/PS in situ microfiber composites(MFC)with different blending ratios were *** results indicated that blending ratio had a great impact on the phase morphology and crystal structure of MFVIM samples,which was different from those of conventional injection molding(CIM)*** ultrafine fibers could be formed under the shear field and could absorb the PPR molecular chains to form hybrid shish-kebab ***,the PPR matrix could also form shish-kebab structures under the effect of strong *** the PS content reached 20%,under the combined action of PS in situ microfibers and highly oriented crystal structure,the tensile strength and Young’s modulus of the sample were obviously improved and the impact strength remained at a relatively high *** a strong and tough balanced PPR based material was *** results provide valuable insights for expanding the industrial and daily-life applications of PPR and show promising development prospects.

关键词： PPR MFVIM In situ microfibers Shearfield Hybrid shish-kebab structures

Protein tyrosine phosphatases:emerging role in cancer therapy resistance

在线全文

学校读者我要写书评

暂无评论

Cancer Communications 2024年第6期44卷 637-653页

作者： Min Zhao wen shuai Zehao Su Ping Xu Aoxue Wang Qiu Sun Guan Wang Innovation Center of Nursing Research Nursing Key Laboratory of Sichuan ProvinceDepartment of BiotherapyCancer Center and State Key Laboratory of BiotherapyNational Clinical Research Center for GeriatricsWest China HospitalWest China School of NursingSichuan UniversityChengduSichuanP.R.China West China Biomedical Big Data Center Med-X Center for InformaticsSichuan UniversityChengduSichuanP.R.China Emergency Department Zigong Fourth People’s HospitalChengduSichuanP.R.China

Background:Tyrosine phosphorylation of intracellular proteins is a posttranslational modification that plays a regulatory role in signal transduction during cellular *** of signal transduction proteins caused by protein tyrosine phosphatases(PTPs)contributed their role as a convergent node to mediate cross-talk between signaling *** the context of cancer,PTP-mediated pathways have been identified as signaling hubs that enabled cancer cells to mitigate stress induced by clinical *** is achieved by the promotion of constitutive activation of growth-stimulatory signaling pathways or modulation of the immune-suppressive tumor *** evidences suggested that anticancer drugs will release their greatest therapeutic potency when combined with PTP inhibitors,reversing drug resistance that was responsible for clinical failures during cancer *** covered:This review aimed to elaborate recent insights that supported the involvement of PTP-mediated pathways in the development of resistance to targeted therapy and immune-checkpoint *** opinion:This review proposed the notion of PTP inhibition in anticancer combination therapy as a potential strategy in clinic to achieve long-term tumor *** clinical trials are currently underway to assess the safety and efficacy of combination therapy in advanced-stage tumors.

关键词： cancer treatment combination therapy drug resistance protein tyrosine phosphatase

Curcumin modulates oxidative stress to inhibit pyroptosis and improve the inflammatory microenvironment to treat endometriosis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第3期11卷 102-105页

作者： Jie Ding Shanshan Mei Kaili Wang wen Cheng shuai Sun Zhexin Ni Xiaoqiu Wang Chaoqin Yu Department of Gynecology of Traditional Chinese Medicine Changhai Hospital Affiliated to Naval Medical UniversityShanghai 200433China Obstetrics and Gynecology Department The First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhouZhejiang 310006China Department of Pharmaceutical Sciences Beijing Institute of Radiation MedicineBeijing 100850China Obstetrics and Gynecology Hospital of Fudan University Shanghai 200433China

Endometriosis(EM)is a common disease that affects approximately 10%-15%of women of childbearing *** pathogenesis of EM is unclear,but studies have shown a strong association between EM and inflammation,as well as oxidative stress.^(1) Pyroptosis is also called inflammatory cell *** pyroptosis occurs,it activates a strong inflammatory *** is associated with oxidative stress,and Ros act as intermediate triggers to activate pyroptosi.

关键词： inflammatory death oxidative

Future changes in precipitation and water availability over the Tibetan Plateau projected by CMIP6 models constrained by climate sensitivity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Atmospheric and Oceanic Science Letters 2024年第5期17卷 40-46页

作者： Hui Qiu Tianjun Zhou Liwei Zou Jie jiang Xiaolong Chen shuai Hu State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina University of the Chinese Academy of Sciences BeijingChina

Precipitation projections over the Tibetan Plateau(TP)show diversity among existing studies,partly due to model *** to develop a reliable projection remains ***,based on the IPCC AR6–assessed likely range of equilibrium climate sensitivity(ECS)and the climatological precipitation performance,the authors constrain the CMIP6(phase 6 of the Coupled Model Intercomparison Project)model projection of summer precipitation and water availability over the *** best estimates of precipitation changes are 0.24,0.25,and 0.45 mm d^(−1)(5.9%,6.1%,and 11.2%)under the Shared Socioeconomic Pathway(SSP)scenarios of SSP1–2.6,SSP2–4.5,and SSP5–8.5 from 2050–2099 relative to 1965–2014,*** corresponding constrained projections of water availability measured by precipitation minus evaporation(P–E)are 0.10,0.09,and 0.22 mm d^(−1)(5.7%,4.9%,and 13.2%),*** increase of precipitation and P–E projected by the high-ECS models,whose ECS values are higher than the upper limit of the likely range,are about 1.7 times larger than those estimated by constrained ***,there is a larger increase in precipitation and P–E over the eastern TP,while the western part shows a relatively weak difference in precipitation and a drier trend in P–*** wetter TP projected by the high-ECS models resulted from both an approximately 1.2–1.4 times stronger hydrological sensitivity and additional warming of 0.6℃–1.2℃ under all three scenarios during 2050–*** study emphasizes that selecting climate models with climate sensitivity within the likely range is crucial to reducing the uncertainty in the projection of TP precipitation and water availability changes.

关键词： Tibetan plateau Climate sensitivity Precipitation projection Water availability projection

Clinical efficacy of Baijin pills in the treatment of generalized tonicclonic seizure epilepsy with cognitive impairment

在线全文

学校读者我要写书评

暂无评论

World Journal of Psychiatry 2024年第6期14卷 938-944页

作者： Jing-Bo Li Jing jiang Lian Xue shuai Zhao Hong-Quan Liu Department of Neurology The Affiliated Hospital of Integrated Traditional Chinese and Western MedicineNanjing University of Chinese MedicineNanjing 210000Jiangsu ProvinceChina Department of Neurology Jiangsu Province Academy of Traditional Chinese MedicineNanjing 210000Jiangsu ProvinceChina

BACKGROUND The generalized tonic-clonic seizure(GTCS)is the most usual variety of epileptic *** is mainly characterized by strong body muscle rigidity,loss of consciousness,a disorder of plant neurofunction,and significant damage to cognitive *** effect of antiepileptic drugs on cognition should also be *** present,there is no effective treatment for patients with epilepsy,but traditional Chinese medicine has shown a significant effect on chronic disease with fewer harmful side effects and should,therefore,be considered for the therapy means of epilepsy with cognitive *** To investigate the clinical efficacy of Baijin pills for treating GTCS patients with cognitive *** This prospective study enrolled patients diagnosed with GTCS between January 2020 and December 2023 and separate them into two groups(experimental and control)using random number table *** control group was treated with sodium valproate,and the experimental group was Baijin pills and sodium valproate for three *** frequency and duration of each seizure,the Montreal Cognitive Assessment Scale(MoCA),and the Quality of Life Rating Scale(QOLIE-31)were recorded before and after *** There were 85 patients included(42 in the control group and 43 in the experimental group).After treatment,the seizure frequency in the experimental group was significantly reduced(P<0.05),and seizure duration was shortened(P<0.01).The total MoCA score in the experimental group significantly increased compared to before treatment(P<0.01),and the sub-item scores,except naming and abstract generalization ability,significantly increased(P<0.05),whereas the total MoCA score in the control group significantly decreased after treatment(P<0.05).The QOLIE-31 score of the experimental group increased significantly after treatment compared to before treatment(P<0.01).CONCLUSION Baijin pills have a good clinical effect on epilepsy with cognitive dysfunction.

关键词： Epilepsy Generalized tonic-clonic seizure Cognitive impairment Traditional Chinese medicine Baijin pills

Energy beam-based direct and assisted polishing techniques for diamond:A review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Extreme Manufacturing 2024年第1期6卷 93-124页

作者： Zhuo Li Feng jiang Zhengyi jiang Zige Tian Tian Qiu Tao Zhang Qiuling wen Xizhao Lu Jing Lu Hui Huang Institute of Manufacturing Engineering Huaqiao UniversityXiamen 361021People’s Republic of China School of Mechanical MaterialsMechatronic and Biomedical EngineeringUniversity of WollongongWollongongNSW 2522Australia College of Mechanical Engineering and Automation Huaqiao UniversityXiamen 361021People’s Republic of China State Key Laboratory of High Performance Tools Huaqiao UniversityXiamen 361021People’s Republic of China

Diamond is a highly valuable material with diverse industrial applications,particularly in the fields of semiconductor,optics,and high-power ***,its high hardness and chemical stability make it difficult to realize high-efficiency and ultra-low damage machining of *** address these challenges,several polishing methods have been developed for both single crystal diamond(SCD)and polycrystalline diamond(PCD),including mechanical,chemical,laser,and ion beam processing *** this review,the characteristics and application scope of various polishing technologies for SCD and PCD are ***,various energy beam-based direct and assisted polishing technologies,such as laser polishing,ion beam polishing,plasma-assisted polishing,and laser-assisted polishing,are *** current research progress,material removal mechanism,and infuencing factors of each polishing technology are *** some of these methods can achieve high material removal rates or reduce surface roughness,no single method can meet all the ***,the future development prospects and application directions of different polishing technologies are presented.

关键词： single crystal diamond polycrystalline diamond energy beam polishing technology material removal mechanism influencing factors

Distributed trusted demand response bidding mechanism empowered by blockchain

在线全文

学校读者我要写书评

暂无评论

Intelligent and Converged Networks 2024年第3期5卷 181-191页

作者： Lei Wang Tong Li Chao Yang jiang Chen Yang Liu shuai Ren State Grid Liaoning Electric Power Co. Ltd.Shenyang 110000China Liaoning Electric Power Research Institute of State Grid Corporation of China Shenyang 110000China

In the demand response process involving multi-agent participation,multiple parties’interests are involved and response execution status supervision is *** centralized demand response systems lack trust *** the same time,traditional centralized cloud management can no longer support massive terminal services,resulting in delays in demand response *** build a distributed trusted demand response architecture based on blockchain,illustrating the information interaction process in the demand bidding process and container-based edge-side heterogeneous resource *** also propose a demand bidding algorithm that takes into account both the day-ahead market and the intraday market,aiming to maximize the aggregator’s *** addition,a virtual resource management algorithm to support demand response tasks is also proposed to optimize computing resource allocation and meet business latency *** results demonstrate that compared with only cloud computing or edge computing,the solution we proposed can reduce response delay by more than 39% for the sample *** cost is saved by about 10.25%during container scheduling.

关键词： demand response blockchain edge and cloud computing demand bidding virtual resource management

Facile synthesis of accordion-like porous carbon from waste PET bottles-based MIL-53(Al)and its application for high-performance Zn-ion capacitor

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Green Energy & Environment 2024年第7期9卷 1138-1150页

作者： Jiaxin Li shuai Zhang Yumeng Hua Yichao Lin Xin wen Ewa Mijowska Tao Tang Xuecheng Chen Rodney S.Ruoff Faculty of Chemical Technology and Engineering West Pomeranian University of TechnologyPiastow Ave.4271-065SzczecinPoland Key State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun130022China School of Safety Engineering China University of Mining and TechnologyXuzhou221116China Institute of Advanced Electrical Materials Qingdao University of Science and TechnologyQingdao266042China Institute for Basic Science Center for Multiple Dimensional Carbon Materials Ulsan44919Republic of Korea Department of Chemistry Ulsan National Institute of Science and Technology(UNIST)Ulsan44919Republic of Korea Department of Materials Science and Engineering Ulsan National Institute of Science and Technology(UNIST)Ulsan44919Republic of Korea School of Energy and Chemical Engineering Ulsan National Institute of Science and Technology(UNIST)Ulsan44919Republic of Korea

It is of great scientific and economic value to recycle waste poly(ethylene terephthalate)(PET)into high-value PET-based metal organic frameworks(MOFs)and further convert it into porous carbon for green energy storage *** the present study,a facile and costeffective hydrothermal process was developed to direct recycle waste PET bottles into MIL-53(Al)with a 100% conversation,then the MOFderived porous carbon was assembled into electrodes for high-performance *** results indicated that the as-synthesized carbon exhibited high SSA of 1712 m^(2)g^(-1)and unique accordion-like structure with hierarchical *** to these advantageous characters,the assembled three-electrode supercapacitor displayed high specific capacitances of 391 F g^(-1)at the current density of 0.5 A g^(-1)and good rate capability of 73.6% capacitance retention at 20 A g^(-1)in 6 mol L^(-1)KOH ***,the assembled zinc ion capacitor still revealed outstanding capacitance of 335 F g^(-1)at 0.1 A g^(-1),excellent cycling stability of 92.2% capacitance retention after 10000 cycles and ultra-high energy density of 150.3 Wh kg^(-1)at power density of 90 W kg^(-1)in 3 mol L^(-1)ZnSO_(4)*** is believed that the current work provides a facile and effective strategy to recycle PET waste into high-valuable MOF,and further expands the applications of MOF-derived carbons for high-performance energy storage devices,so it is conducive to both pollution alleviation and sustainable economic development.

关键词： PET Recycling Porous carbon Supercapacitor Energy storage

Upcycling of Poly(butylene adipate-co-terephthalate)into Dual Covalent Adaptable Networks through Chain Breaking-Crosslinking Strategy

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2024年第10期42卷 1505-1513,I0011页

作者： Bin-Bo Wang Rong Huang Xin Wang Tao jiang Yi Wang shuai Du Fa-Lin Li Jin Zhu Song-Qi Ma Key Laboratory of Synthetic and Biological Colloids Ministry of EducationSchool of Chemical and Material EngineeringJiangnan UniversityWuxi214122China Key Laboratory of Bio-based Polymeric Materials Technology and Application of Zhejiang Province Divisions of Polymers and CompositesNingbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo315201China University of Chinese Academy of Sciences Beijing100049China

Poly(butylene adipate-co-terephthalate)(PBAT),a widely studied biodegradable material,has not effectively addressed the problem of plastic *** into consideration the cost-effectiveness,upcycling PBAT should take precedence over direct composting *** present work adopts a chain breaking-crosslinking strategy,upcycling PBAT into dual covalent adaptable networks(CANs).During the chainbreaking stage,the ammonolysis between PBAT and polyethyleneimine(PEI)established the primary crosslinked ***,styrene maleic anhydride copolymer(SMA)reacted with the hydroxyl group,culminating in the formation of dual covalent adaptable *** contrast to PBAT,the PBAT-dual-CANs exhibited a notable Young's modulus of 239 MPa,alongside an inherent resistance to creep and *** to catalysis from neighboring carboxyl group and excess hydroxyl groups,the PBAT-dual-CANs exhibited fast stress ***,they could be recycled through extrusion and hot-press reprocessing,while retaining their *** straightforward strategy offers a solution for dealing with plastic waste.

关键词： Poly(butylene adipate-co-terephthalate) Dynamic crosslinked networks Chain breaking-crosslinking strategy Upcycle Recycle

Spatiotemporal changes in sunshine duration and its influential factors in Chongqing,China from 1961 to 2020

在线全文

学校读者我要写书评

暂无评论

Journal of Mountain Science 2024年第6期21卷 2005-2024页

作者： LI Jun XIA Hongxuan jiang Jinge XU Weifeng wen Di XU Junfeng College of Geography and Tourism Chongqing Normal UniversityChongqing 401331China Key Laboratory of GIS Application of Chongqing Chongqing 401331China Chongqing Key Laboratory of Earth Surface Processes and Environmental Remote Sensing in Three Gorges Reservoir area Chongqing 401331China Institute of Remote Sensing and Earth Sciences School of Institute of Remote Sensing and Earth SciencesSchool of ScienceHangzhou Normal UniversityHangzhou 311121China

The surface solar radiation in most parts of the world has undergone a phenomenon known as global dimming and brightening,characterized by an initial decrease followed by an *** a result,the sunshine duration(SD)has decreased in the past 60 *** the backdrop of global dimming and brightening,SD has decreased to varying degrees in many regions of *** the observed data of SD,cloud amount(total cloud amount and low cloud amount,abbreviated as TCA and LCA),precipitation,and relative humidity(RH)from 34 meteorological stations in Chongqing during the period of 1961-2020,along with a digital elevation model(DEM)with a resolution of 90 m,this study analyzed the spatiotemporal variations and influencing factors of *** analysis employed methods such as linear regression,Mann-Kendall test,wavelet transformation,and DEM-based possible SD distributed *** results showed that the annual SD in Chongqing has significantly decreased over the last 60 years,with a decreasing interannual trend rate(ITR)of 40.4 h/*** for no obvious trend in spring,SD decreased significantly in summer,autumn and winter at the ITR of 21.1 h/10a,8.5 h/10a and 7.5 h/10a,*** abrupt decrease in the annual SD was found in *** difference before and after the abrupt decrease was 177.7 *** difference before and after the abrupt decrease was 177.7 *** annual SD possessed the oscillation period of *** spatial heterogeneity of the mean annual SD during the last 60 years was *** distribution of SD in Chongqing is high in the northeast and low in the *** addition,about 73%of the total area in Chongqing showed a significant and very significant decreasing *** regions with significant changes are mainly concentrated in the regions with altitudes of 200~1000 *** increasing LCA was the main cause of the decrease of the annual SD in the regions with 200-400 m altitude decreased the most and changed the *** LCA is the prim

关键词： Sunshine duration Spatiotemporal changes Mann-Kendall test Wavelet analysis Geodetector model