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Prostate artery embolization on lower urinary tract symptoms related to benign prostatic hyperplasia: A systematic review and metaanalysis

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World Journal of Clinical Cases 2022年第32期10卷 11812-11826页

作者： Xiao-Yan Wang Yu-Meng Chai wen-hui huang Yong Zhang Department of Urology Beijing Tiantan HospitalCapital Medical UniversityBeijing 100070China School of Information Science and Engineering Shandong Normal UniversityJinan 250014Shandong ProvinceChina

BACKGROUND Prostate artery embolization(PAE)is a promising minimally invasive therapy that improves lower urinary tract symptoms(LUTS)related to benign prostatic hyperplasia(BPH).Transurethral resection of the prostate(TURP)is the gold standard therapy for LUTS/*** To evaluate the efficacy and safety of PAE vs TURP on LUTS related to *** A literature review was performed to identify all published articles on PAE vs TURP for LUTS/*** included PubMed,Embase,Cochrane library databases,and Chinese databases before June 2022.A systematic review and meta-analysis were *** measurements were combined by calculating the mean difference with a 95%confidence *** analysis was carried out using Review Manager *** Eleven studies involving 1070 participants were *** with the TURP group,the PAE group had a similar effect on the International Index of Erectile Function(IPSS)score,Peak urinary flow rate(Qmax),postvoid residual volume(PVR),Prostate volume(PV),prostatic specific antigen(PSA),The International Index of Erectile Function short form(IIEF-5)scores,and erectile dysfunction during 24 mo *** quality of life(QoL)score,lower rate of retrograde ejaculation and shorter hospital stay in the PAE *** was no participant death in either group.A higher proportion of haematuria,urinary incontinence and urinary stricture was identified in the TURP *** PAE may be an appropriate option for elderly patients,patients who are not candidates for surgery,and patients who do not want to risk the potential adverse effects of *** with large cases and long follow-up time are needed to validate results.

关键词： Lower urinary tract symptoms Benign prostatic hyperplasia Meta-analysis Prostate artery embolization Transurethral resection of the prostate

Laser-RF synchronization based on digital phase detector

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Nuclear Science and Techniques 2017年第4期28卷 97-102页

作者： Jin Yang Ying-Chao Du Li-Xin Yan Gang huang Qiang Du Yi-Lun Xu wen-hui huang Huai-Bi Chen Department of Engineering Physics Tsinghua UniversityBeijing 100084 China Key Laboratory of Particle and Radiation Imaging (Tsinghua University) Ministry of Education Beijing 100084 China Lawrence Berkeley National Laboratory BerkeleyCA 94720 USA

Laser oscillator synchronization with RF reference signal is ultra-important for a modern light source based on the *** Tsinghua Thomson scattering X-ray source,we have synchronized the mode-locked laser oscillator to RF reference signal with 48.2 fs RMS relative *** fundamental and harmonic signals derived from photo diode detection are used for laser-RF synchronization in our *** fundamental signal is for coarse laser-RF synchronization and multiple laser oscillator *** harmonic signal is for high precise phase *** digital phase detector is implemented in the synchronization scheme for less noise,replacing the mixing to DC phase detection *** digital processing algorithm for synchronization is commonly used in low-level RF control *** order to test the phase locking loop logic without damaging the real laser oscillator,a laser oscillator emulator was developed for phase *** paper will report the laser-RF synchronization scheme and its *** laser oscillator emulator system will also be introduced here.

关键词： Laser oscillator Synchronization RF LLRF Emulator

Beam position monitors as precise phase pickups for beam energy measurement at the Compact Pulsed Hadron Source

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Nuclear Science and Techniques 2019年第2期30卷 1-9页

作者： Min-wen Wang Qing-Zi Xing Shu-Xin Zheng Zhong-Ming Wang Meng-Tong Qiu Xia-Ling Guan Xue-Wu Wang wen-hui huang Laboratory of Particle and Radiation Imaging Ministry of EducationTsinghua University Laboratory for Advanced Radiation Sources and Application Tsinghua University Department of Engineering Physics Tsinghua University State Key Laboratory of Intense Pulsed Radiation Simulation and Effect Northwest Institute of Nuclear Technology

The 13-MeV proton linac of the Compact Pulsed Hadron Source(CPHS) at Tsinghua University, China,is composed of a 50-keV electron cyclotron resonance proton source, a 3-MeV four-vane-type radio-frequency quadrupole(RFQ) accelerator, and a drift tube linac(DTL). Precise measurement of the beam energies at the exit of the RFQ and the DTL is critical for DTL commissioning. Two button-type beam position monitors(BPMs) installed downstream of the RFQ are used to perform the measurement using a time-of-flight method. The effects of several factors on phase measurement accuracy are analyzed. The phase measurement accuracy of the BPMs at CPHS is better than ± 1.03° at 325 MHz after corrections,corresponding to an energy measurement error of± 0.07%. The beam energy measured at the exit of the RFQ is 2.994 ± 0.0022 MeV,which is consistent with the design value.

关键词： Beam energy Time of flight Beam position monitor Phase pickup

Successful treatment of pyoderma gangrenosum with concomitant immunoglobulin A nephropathy: A case report and review of literature

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World Journal of Clinical Cases 2018年第13期6卷 703-706页

作者： Xiao-Li Li Zhi-Gang Ma wen-hui huang Er-Qing Chai Yun-Fei Hao Department of Nephrology Gansu Provincial Hospital Cerebrovascular Disease Center Gansu Provincial Hospital

Pyoderma gangrenosum(PG)is an uncommon ulcerative cutaneous condition of an unknown etiology and is often associated with immune ***,PG rarely shows visceral involvement,especially in the kidney.A 20-year-old female presented with pedal edema and skin ulceration of both lower *** skin lesion began as an erythematous plaque and then became a *** also complained of abdominal distension and a decreasing urine *** data showed high proteinuria,hypoalbuminemia and *** skin and kidney were *** pathological results indicated PG and immunoglobulin A(IgA)*** patient was finally cured with prednisolone in combination with cyclosporine A(CsA).

关键词： Pyoderma gangrenosum Immunoglobulin A nephropathy Treatment

Simultaneous fluorescence and Compton scattering computed tomography based on linear polarization X-ray

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Nuclear Science and Techniques 2024年第10期35卷 41-50页

作者： Zhi-Jun Chi Hong-Ze Zhang Jin Lin Xuan-Qi Zhang Hao Ding Qi-Li Tian Zhi Zhang Ying-Chao Du wen-hui huang Chuan-Xiang Tang Key Laboratory of Beam Technology of the Ministry of Education School of Physics and AstronomyBeijing Normal UniversityBeijing 100875China Key Laboratory of Particle and Radiation Imaging of the Ministry of Education Department of Engineering PhysicsTsinghua UniversityBeijing 100084China

Purpose To propose a method for simultaneous fluorescence and Compton scattering computed tomography by using linearly polarized *** Monte Carlo simulations were adopted to demonstrate the feasibility of the proposed *** the simulations,the phantom is a polytetrafluoroethylene cylinder inside which are cylindrical columns containing aluminum,water,and gold(Au)-loaded water solutions with Au concentrations ranging between 0.5 and 4.0 wt%,and a parallel-hole collimator imaging geometry was *** light source was modeled based on a Thomson scattering X-ray *** phantom images for both imaging modalities were reconstructed using a maximumlikelihood expectation maximization *** Both the X-ray fluorescence computed tomography(XFCT)and Compton scattering computed tomography(CSCT)images of the phantom were accurately reconstructed.A similar attenuation contrast problem for the different cylindrical columns in the phantom can be resolved in the XFCT and CSCT *** interplay between XFCT and CSCT was analyzed,and the contrast-to-noise ratio(CNR)of the reconstruction was improved by correcting for the mutual influence between the two imaging *** with K-edge subtraction imaging,XFCT exhibits a CNR advantage for the *** Simultaneous XFCT and CSCT can be realized by using linearly polarized *** synergy between the two imaging modalities would have an important application in cancer radiation therapy.

关键词： X-ray fluorescence computed tomography Compton scattering computed tomography Linear polarization Thomson scattering X-ray source Monte Carlo simulation

Dynamic Analysis of a Structure Using Taylor Expansion Stochastic Finite Element Method

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International Journal of Plant Engineering and Management 2008年第4期13卷 191-199页

作者： MO wen-hui huang Qi-bo College of Mechanical Engineering Huazhong University of Science and Technology Wuhan 430074 P. R. China

Due to spatial variability of material property, Young＇ s modulus is assumed to be a stochastic process. This paper proposes a new method of calculating stochastic field, which includes the information of nodes and the midpoint. The method is of high accuracy, and is easy to program. It is an improvement of the midpoint method of stochastic field. In the case of material properties, geometry parameters and applied loads are assumed to be stochastic, the vibration equation of a structure is transformed into a static problem using Newmark method. The Taylor expansion stochastic finite element method（TSFEM） is extended for the structure vibration analysis. An example is given and the calculated results are compared to validate the proposed methods.

关键词： dynamic analysis structure TSFEM improved midpoint method

Novel and functional DNA sequence variants within the GATA5 gene promoter in ventricular septal defects

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World Journal of Pediatrics 2014年第4期10卷 348-353页

作者： Ji-Ping Shan Xiao-Li Wang Yuan-Gang Qiao Hong-Xin Wan Yan wen-hui huang Shu-Chao Pang Bo Yan Shandong Provincial Key Laboratory of Cardiac Disease Diagnosis and Treatment Jining Medical University Affi liated HospitalJining Medical University Division of Magnetic Resonance Imaging Jining Medical University Affi liated HospitalJining Medical University Shandong Provincial Sino-US Cooperation Research Center for Translational Medicine Jining Medical University Affi liated HospitalJining Medical UniversityJiningShandongChina

Background:Congenital heart disease(CHD)is the most common human birth *** causes for CHD remain largely *** transcription factor 5(GATA 5)is an essential regulator for the heart *** in the GATA5 gene have been reported in patients with a variety of *** misregulation of gene expression have been associated with human diseases,we speculated that changed levels of cardiac transcription factors,GATA5,may mediate the development of ***:In this study,GATA5 gene promoter was genetically and functionally analyzed in large cohorts of patients with ventricular septal defect(VSD)(n=343)and ethnic-matched healthy controls(n=348).Results:Two novel and heterozygous DNA sequence variants(DSVs),g.61051165A>G and g.61051463delC,were identified in three VSD patients,but not in the *** cultured cardiomyocytes,GATA5 gene promoter activities were significantly decreased by DSV g.61051165A>G and increased by DSV ***,fathers of the VSD patients carrying the same DSVs had reduced diastolic function of left *** SNPs,g.61051279C>T(rs77067995),g.61051327A>C(rs145936691)and g.61051373G>A(rs80197101),and one novel heterozygous DSV,g.61051227C>T,were found in both VSD patients and controls with similar ***:Our data suggested that the DSVs in the GATA5 gene promoter may increase the susceptibility to the development of VSD as a risk factor.

关键词： congenital heart disease GATA5 promoter ventricular septal defect

Tectonic evolution and accumulation characteristics of Carboniferous shale gas in Yadu-Ziyun-Luodian aulacogen, Guizhou Province, South China

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China Geology 2023年第4期6卷 646-659页

作者： Kun Yuan wen-hui huang Ting Wang Shi-zhen Li Xiang-can Sun Xin-xin Fang Jun-ping Xiao Jun Guo Oil and Gas Resources Survey China Geological SurveyMinistry of Natural ResourcesBeijing 100083China China University of Geosciences(Beijing) Beijing 100083China The key Laboratory of Unconventional Oil and Gas Geology China Geological SurveyBeijing 100083China Institute of Geomechanics Chinese Academy of Geological SciencesBeijing 100081China No.814 Geological Party East China Bureau of Mineral Exploration and DevelopmentZhenjiang 212005China Hunan Institute of Geophysics and Geochemistry Changsha 410000China

The Yadu-Ziyun-Luodian aulacogen(YZLA) developed into being NW-trending in the Late Paleozoic,and was considered as an important passive continental margin aulacogen in Guizhou Province, South China. This tectonic zone is considered a large intracontinental thrust-slip tectonic unit, which has undergone a long period of development. It was ultimately determined in the Yanshanian, where the typical Upper Paleozoic marine shales were deposited. In 2021, Well QSD-1 was deployed in the Liupanshui area at the northwest margin of the aulacogen, and obtained a daily shale gas flow of 11011 m3in the Carboniferous Dawuba Formation. It thus achieved a breakthrough in the invesgation of shale gas in the Lower Carboniferous in South China, revealing relatively good gas-bearing properties and broad exploration prospects of the aulacogen. Being different from the Lower Paleozoic strata in the Sichuan Basin and the Yichang area of the Middle Yangtze, the development of the Carboniferous Dawuba Formation in the aulacogen exhibits the following characteristics:(1) The Lower Carboniferous shale is thick and widely distributed, with interbedded shale and marlstone of virous thickness;(2) The total organic carbon(TOC) content of the shale in the Dawuba Formation ranges from 1% to 5%, with an average of 2%, and the thermal maturity of organic matter(Ro) varies from 1% to 4%, with an average of2.5%, indicating good hydrocarbon generation capacity;(3) The main shale in the aulacogen was formed during the fault subsidence stage from the Middle Devonian to the Early Permian. Although the strong compression and deformation during the late Indosinian-Himalayan played a certain role in destroying the formed shale gas reservoirs, comparative analysis suggests that the area covered by the current Triassic strata has a low degree of destruction. It therefore provides good conditions for shale gas preservation,which can be regarded as a favorable area for the next exploration.

关键词： Shale gas Aulacogen Carboniferous Shale and marlstone Organic carbon Organic matter Hydrocarbon generation capacity Tectonic evolution Accumulation characteristics

Geochemical characteristics and sedimentary environment of the Middle Devonian organic-rich shales in the Northwest of Guizhong Depression, Southwest China

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China Geology 2020年第4期3卷 567-574页

作者： Kun Yuan wen-hui huang Xin-xin Fang Shi-zhen Li Ting Wang Tuo Lin Guo-heng Liu China University of Geosciences(Beijing) Beijing 100083China Oil and Gas Resources Survey China Geological SurveyMinistry of Natural Resources Beijing 100083China Institute of Geomechanics Chinese Academy of Geological SciencesBeijing 100081China

In order to figure out the redox conditions and paleo-sedimentary environment of the Middle Devonian shales in the northwest of Guizhong Depression,the trace element analysis was conducted on the Middle Devonian cores(320.35–938.50 m)of the typical shale gas investigation well(GY-1)at a 1.50 m sampling interval through X-ray fluorescence spectroscopy(XRF)and inductively coupled plasma mass spectrometry(ICP-MS).According to the test result,the average values of V/(V+Ni),V/Cr and Ni/Co in Nabiao formation(Fm.)are larger than 0.67,4.65 and 7.71 respectively,and Nabiao *** rich in biological assemblages such as tabasheer,ammonite,*** evidences indicate the rising sea level rose relatively in the sedimentation period of Nabiao *** a deepwater shelf environment,which was favorable for the preservation of organic *** V/(V+Ni),V/Cr and Ni/Co in Luofu *** Tangting *** 0.38–0.65,0.73–4.10 and 3.70–6.72 respectively,indicating that the sea level dropped relatively in their sedimentation period,during which the water bodies became shallow,and the sedimentary environment was a weak oxidizing shallow water shelf *** addition,the variation of TOC has a high correlation with the enrichment degree of Ba element,indicating the favorable conditions for the enrichment and preservation of organic matters under an oxygen-deficient ***,according to the identification of trace element indexes,the northwest of Guizhong Depression experienced the sedimentary cycle of relative rise to relative fall of sea level from bottom to top in the Middle Devonian sedimentation *** relative sea level rose to the highest in the sedimentation period of Nabiao Fm.,in which the organic-rich shales with stable thickness and high organic content were ***,the Nabiao *** be regarded as the favorable exploration target interval in this area.

关键词： Organic-rich shale Devonian Geochemistry Sedimentary environment Guizhong Depression Geological survey engineering Guizhou Province Southwest China