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Effect　of　methylflavonolamine　on　acute　forebrain　is　chemiare　perfusion　in　juryin rat

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中国药理学与毒理学杂志 1996年第2期 10-13页

作者： DUAN wen-Zhen 1, TANG Yun-Zhao, LIANG yue-Qin, DUN wen (Department of Pharmacology, Shanxi Medical College, Taiyuan 030001)

用Ｐｕｌｓｉｎｅｌｉ法造成大鼠急性前脑缺血４０ｍｉｎ，然后开夹再灌注１ｈ．在缺血前５ｍｉｎ，再灌前５ｍｉｎ以及再灌３０ｍｉｎ时分别ｉｖ甲基黄酮醇胺（ＭＦＡ）１０和２０ｍｇ·ｋｇ－１．结果表明：ＭＦＡ的两个剂量组均可降... 详细信息

用Ｐｕｌｓｉｎｅｌｉ法造成大鼠急性前脑缺血４０ｍｉｎ，然后开夹再灌注１ｈ．在缺血前５ｍｉｎ，再灌前５ｍｉｎ以及再灌３０ｍｉｎ时分别ｉｖ甲基黄酮醇胺（ＭＦＡ）１０和２０ｍｇ·ｋｇ－１．结果表明：ＭＦＡ的两个剂量组均可降低再灌注引起的脑钙含量增加，减轻脑水肿，抑制脂质过氧化物丙二醛生成，并缓解脑组织中乳酸脱氢酶的释放；同时明显改善脑电图，减轻大脑锥体细胞的变性坏死．提示：ＭＦＡ对大鼠急性脑缺血再灌注损伤有保护作用，其作用可能是通过降低钙在脑组织病理性累积，从而抑制进一步的脂质过氧化等病理生理变化实现的．

关键词：脑缺血再灌注损伤钙甲基黄酮醇胺脑电描记术

Strong decays of P-wave mixing heavy-light 1^+ states

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Chinese Physics C 2018年第12期42卷 1-8页

作者： Zhi-hui Wang Yi Zhang Tian-Hong Wang yue Jiang Qiang Li Guo-Li Wang School of Electrical &: Information Engineering North Minzu University Yinchuan 750021 China Department of Physics Harbin Institute of Technology Harbin 150001 China Institute of Theoretical Physics Chinese Academy of Sciences Beijing 100190 China

Many P-wave mixing heavy-light 1^＋ states have not yet been discovered by experiment, while others have been discovered but without width information, or with large uncertainties on the widths. In this paper, the strong decays of the P-wave mixing heavy-light 1^＋ states D^0, D^±, D^±, B^0, B^±： and Bs are studied by the improved Bethe SMpeter （B-S） method with two conditions of mixing angle 0： one is 0 = 35.3°; the other is considering a correction to the mixing angle 0=35.3°＋θ1. Valuable predictions for the strong decay widths are obtained： F（D1^0）=232 MeV, r（D1^0）=21.5 MeV, F（D1^±）=232 MeV, F（D1^±）=21.5 MeV, F（Ds1^±）=0.0101 MeV,Г（Ds1^±l）=0.950 MeV, F（BГ^±＋）=263 MeV, F（B1^±=16.8 MeV, F（B′s1）=0.01987 MeV and F（B,1）=0.412 MeV. It is found that the decay widths of D~ and Bsl are very sensitive to the mixing angle. The results will provide theoretical assistance to future experiments.

关键词： P-wave mixing states strong decay mixing angle improved B-S method

Synthesis and Structure of Vanadium-barium Complex of 2,4,6-Tripicolinato with 20-Member Macrocyclic Cavities

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Chinese Chemical Letters 2003年第7期14卷 740-743页

作者： Yu Xia DIAO Yang TIAN Si hui ZHAN wen Xing ZHANG Xiu Ling JIAO Dai Rong CHEN School of Chemistry and Chemical Engineering Shandong UniversityJinan 250100

A new heteronuclear complex, dimer [(2-OH2)2Ba2(H2O)4][VO2(tpa)]24H2O (tpa: 2,4,6-tripicolinate trianion), was synthesized and structurally determined by X-ray diffraction technique where all hydrogen atoms have been located directly. The coordination geometry of V(V) ion is a distorted trigonal bipyrimid and that of Ba(II) ion is a capped square antiprism. One 2-O bridging bond and two hydrogen bonds act between the coordination geometries. A 1-D extended porous construction containing 20-member cavities is observed in the crystal.

关键词： Heteronuclear vanadium-barium complex synthesis cavity structure.

SYNTHESIS OF 11 α-HYDROXY-AND 11β-CHLORO-ARTEMISININ

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Chinese Chemical Letters 1993年第2期4卷 99-100页

作者： Ying Li De wen LU hui Bin ZHANG Shanghai Institute of Materia Medica Academia SinicaShanghai 200031 present address:Department of Chemistry Changshu College.Changshu 215500 present address:Division of Medicinal Chemistry Chinese Pharmaceutical UniversityNanjing 210009

11α-Hydroxy-and 11β-chloro-artemisinin have been prepared from artemisinin

关键词： CHLORO-ARTEMISININ HYDROXY-AND 11 SYNTHESIS OF 11 OH 429

Antimony Selenide Thin Film Solar Cells with an Electron Transport Layer of Alq3

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Chinese Physics Letters 2020年第10期37卷 125-130页

作者： wen-Jian Shi Ze-Ming Kan Chuan-hui Cheng wen-hui Li Hang-Qi Song Meng Li Dong-Qi Yu Xiu-Yun Du Wei-Feng Liu Sheng-Ye Jin Shu-Lin Cong School of Physics and Electronic Technology Liaoning Normal UniversityDalian 116029China School of Physics Dalian University of TechnologyDalian 116024China Mechanical and Electrical Engineering College Hainan UniversityHaikou 570228China State Key Laboratory of Molecular Reaction Dynamics Dalian Institute of Chemical PhysicsChinese Academy of SciencesDalian 116023 China

We fabricated Sb 2 Se 3 thin film solar cells using tris(8-hydroxy-quinolinato)aluminum(Alq 3)as an electron transport layer by vacuum thermal *** small organic molecule of N,N'-bis(naphthalen-1-yl)-N,N'-bis(phenyl)benzidine(NPB)was used as a hole transport *** took ITO/NPB/Sb 2 Se 3/Alq 3/Al as the device *** open circuit voltage(V o c)of 0.37 V,a short circuit current density(J s c)of 21.2 mA/cm 2,and a power conversion efficiency(PCE)of 3.79%were obtained on an optimized device.A maximum external quantum efficiency of 73%was achieved at 600 *** J s c,V o c,and PCE were dramatically enhanced after introducing an electron transport layer of Alq *** results suggest that the interface state density at Sb 2 Se 3/Al interface is decreased by inserting an Alq 3 layer,and the charge recombination loss in the device is *** work provides a new electron transport material for Sb 2 Se 3 thin film solar cells.

关键词： transport Solar interface

Identification of rare paired box 3 variant in strabismus by whole exome sequencing

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International Journal of Ophthalmology(English edition) 2017年第8期10卷 1223-1228页

作者： hui-Min Gong Jing Wang Jing Xu Zhan- Yu Zhou Jing- wen Li Shu-Fang Chen Ophthalmologic Center Qingdao Municipal Hospital theAffiliated Municipal Hospital of Qingdao University Qingdao266000 Shandong Province China Department of Ophthalmology Dezhou People's HospitalDezhou 253000 Shandong Province China Department of Ophthalmology Weifang People's HospitalWeifang 261041 Shandong Province China Department of Medical Equipment Weifang People's Hospital Weifang 261041 Shandong Province China

AIM： To identify the potentially pathogenic gene variants that contributes to the etiology of strabismus. METHODS： A Chinese pedigree with strabismus was collected and the exomes of two affected individuals were sequenced using the next-generation sequencing technology. The resulting variants from exome sequencing were filtered by subsequent bioinformatics methods and the candidate mutation was verified as heterozygous in the affected proposita and her mother by sanger sequencing. RESULTS： Whole exome sequencing and filtering identified a nonsynonymous mutation Co434G-T transition in paired box 3 （PAX3） in the two affected individuals, which were predicted to be deleterious by more than 4 bioinformatics programs. This altered amino acid residue was located in the conserved PAX domain of PAX3. This gene encodes a member of the PAX family of transcription factors, which play critical roles during fetal development. Mutations in PAX3 were associated with Waardenburg syndrome with strabismus. CONCLUSION： Our results report that the c.434G-T mutation （p.R145L） in PAX3 may contribute to strabismus, expanding our understanding of the causally relevant genes for this disorder.

关键词： strabismus whole exome sequencing paired box 3

Stochastic Finite Element Method for Mechanical Vibration Based on Conjugate Gradient(CG)

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International Journal of Plant Engineering and Management 2008年第3期13卷 128-134页

作者： MO wen-hui School of Mechanical Science ＆ Engineering Huazhong University of Science and Technology Wuhan 430074 P. R. China

When material properties, geometry parameters and applied loads are assumed to be stochastic, the vibration equation of a system is transformed to static problem by using Newmark method. In order to improve the computational efficiency and to save storage, the Conjugate Gradient （CG） method is presented. The CG is an effective method for solving a large system of linear equations and belongs to the method of iteration with rapid convergence and high precision. An example is given and calculated results are compared to validate the proposed methods.

关键词： stochastic finite element method(SFEM) mechanical vibration conjugate gradient(CG)

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精神分裂症代谢指标与工作记忆相关性研究

临床精神医学杂志 2024年第3期34卷 207-210页

作者：李君伟朱文礼米权慧宋传福蚌埠医科大学附属芜湖市第四人民医院 241002 首都医科大学附属北京安定医院芜湖医院

目的:探索精神分裂症患者代谢指标与工作记忆间的相关性。方法:测量47例入院1周内使用利培酮治疗的精神分裂症患者体质量(weight, WT)、空腹血糖(glucose, GLU)、三酰甘油(triglycerides, TG)、高密度脂蛋白(high density lipoprotein, ... 详细信息

目的:探索精神分裂症患者代谢指标与工作记忆间的相关性。方法:测量47例入院1周内使用利培酮治疗的精神分裂症患者体质量(weight, WT)、空腹血糖(glucose, GLU)、三酰甘油(triglycerides, TG)、高密度脂蛋白(high density lipoprotein, HDL)、腹壁脂肪厚度,使用阳性和阴性症状量表(positive and negative syndrome scale, PANSS)评定精神症状,运用N-back工作记忆测验精神分裂症患者工作记忆。治疗6个月后再次测量WT、GLU、TG、HDL、腹壁脂肪厚度、评定精神症状、测验工作记忆,进行前后对照,并结合一般资料问卷所得结果进行分析。结果:治疗后WT、TG、腹壁脂肪厚度、药物剂量明显高于治疗前,HDL、PANSS明显低于治疗前,差异均有统计学意义(P均<0.05);***(反应时)、***明显高于治疗前,差异均有统计学意义(P均<0.05);三酰甘油差值与***差值呈正相关(r=0.353,P<0.05),腹壁脂肪厚度差值与***差值呈正相关(r=0.322,P<0.05)。结论:精神分裂症患者三酰甘油、腹壁脂肪厚度与工作记忆存在一定相关性,通过控制甘油三脂水平及腹壁脂肪厚度,可能会改善患者工作记忆。

关键词：精神分裂症代谢指标工作记忆

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不同发酵剂对木薯茎叶青贮品质的影响

饲料研究 2024年第5期47卷 94-98页

作者：姜太玲严炜宋记明刘彦培沈正松张林辉李月仙刘光华云南省农业科学院热带亚热带经济作物研究所云南保山678000 云南省草地动物科学研究院云南昆明650212 云南省农业科学院国际农业研究所云南昆明650205

试验探究了不同发酵剂对木薯茎叶青贮品质的影响。试验分为对照组(CK组)和3个处理组(A组、B组、C组)。CK组中不添加任何发酵剂,3个处理组在木薯茎叶原料中分别添加0.02%的发酵剂A、发酵剂B、发酵剂C,每组3个重复,发酵90 d后取样分析。... 详细信息

试验探究了不同发酵剂对木薯茎叶青贮品质的影响。试验分为对照组(CK组)和3个处理组(A组、B组、C组)。CK组中不添加任何发酵剂,3个处理组在木薯茎叶原料中分别添加0.02%的发酵剂A、发酵剂B、发酵剂C,每组3个重复,发酵90 d后取样分析。结果表明,各处理组的干物质、Ca、P含量与CK组无明显变化;C组粗蛋白、粗脂肪、粗灰分含量均最高,分别较CK组升高8.06%、17.84%、2.01%;A组木质素含量最低,较CK组降低14.43%;C组中性洗涤纤维(NDF)、酸性洗涤纤维(ADF)、可溶性碳水化合物(WSC)含量均最低,分别较CK组降低11.40%、16.62%、14.96%。各处理组的所有饲喂价值指标均高于CK组,C组的所有饲喂价值指标均最高。B组pH值、氨态氮、丁酸和氨态氮/总氮的数值均最低,较CK组分别降低8.88%、20.90%、99.48%和26.82%;C组乳酸含量最高,较CK组升高26.03%;A组乙酸含量最低,较CK组降低5.85%。对发酵品质进行综合评分可知,各处理组得分均高于CK组。利用平均隶属函数值对木薯茎叶青贮品质进行综合比较,B组的青贮品质最佳。研究表明,添加微生物发酵剂在一定程度上能够改善木薯茎叶的青贮品质。

关键词：木薯茎叶发酵剂青贮品质营养成分

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