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Porous Organic Cage‑Based Quasi‑Solid‑State Electrolyte with Cavity‑Induced Anion‑Trapping Effect for Long‑life lithium Metal Batteries

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Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-Min Qin Zhongliang li wen‑Xia Su Jia‑Min Hu Hanqin Zou Zhixuan Wu Zhiqin Ruan Yue‑Peng Cai Kang li Qifeng Zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of Hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous li deposition and highly reversible li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous li+flux lithium metal battery

COMPARATIVE EPIDERMAL STUDIES BETWEEN FOSSIL AND EXTANT SPECIES OF GLYPTOSTROBUS (TAXODIACEAE)

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COMPARATIVE EPIDERMAL STUDIES BETWEEN FOSSIL AND EXTANT SPEC...

The potential mechanism and clinical application value of remote ischemic conditioning in stroke

全国系统与进化植物学研讨会暨第九届系统与进化植物学青年研讨会

作者： MA Qing-wen, li cheng-Sen, li Feng-Lan Beijing Museum of Natural History, Beijing 100050, China Institute of Botany, Chinese Academic of Sciences, Beijing 100093, China College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China

As an endemic genus, Glyptostrobus has a unique living species, G. pensilis C. Koch, which is naturally distributed within the Chinese Provinces of Guangdong, Guangxi, Fujian and Yunnan. Leaves of G. pensilis are spirally arranged and comprise three morphotypes: linear, linear-subulate and scale-like. The epidermal structures on both the abaxial and adaxial surfaces of the three morphotypes are very similar. The epidermal cells are elongated within the non-stomatal areas, while they are rectangular with slighily rounded corners on the intrastomatal zones. Pits *** clearly seen in the walls of epidermal cells both on non-stomatal areas and on intrastomatal zones. Stomata on both the abaxial and adaxial outer and inner surfaces of the three morphotypes of leaves are very similar in structure. Stomata apertures are elliptic. The long axes of stomatal apertures are mostly parallel to the mid-vein in linear and linear-subulate leaves, but most stomata are oblique or perpendicular to the mid-vein in scale-like leaves. Guard cells have thickened walls, especially on outer margins. The thickened outer margins of cell walls are reniform in shape. The thickened walls of guard cells form polar lamellae that produce protruding and curved ends at the two poles of the stoma. Commonly the stomata have 5 or 6 subsidiary cells. Stomata are iocated on each side of the mid-vein and distributed on both the abaxial and adaxial surfaces of leaves. In linear leaves, the number of stomata on the abaxial surface is more than that on the adaxial surface and the stomatal band, about 0.3 mm in width, on the abaxial surface comprises 7-10 rows of stomata on each side of the mid-vein, while the band on the adaxial surface has only 1-3 rows of stomata. On each surfaces of the quadrangular linear-subulate leaves, the numbers and distribution of stomata are almost the same. The stomatal band comprises 4-6 rows of stomata and occupies about 0.2 mm in width. There are 2-5 rows of stomata in each s

关键词： Taxodiaceae Glvptostrobus Cuticle Stoma

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Neural Regeneration Research 2025年第6期20卷 1613-1627页

作者： Yajun Zhu Xiaoguo li Xingwei Lei liuyang Tang Daochen wen Bo Zeng Xiaofeng Zhang Zichao Huang Zongduo Guo The First Affiliated Hospital of Chongqing Medical University ChongqingChina

Some studies have confirmed the neuroprotective effect of remote ischemic conditioning against stroke. Although numerous animal researches have shown that the neuroprotective effect of remote ischemic conditioning may be related to neuroinflammation, cellular immunity, apoptosis, and autophagy, the exact underlying molecular mechanisms are unclear. This review summarizes the current status of different types of remote ischemic conditioning methods in animal and clinical studies and analyzes their commonalities and differences in neuroprotective mechanisms and signaling pathways. Remote ischemic conditioning has emerged as a potential therapeutic approach for improving stroke-induced brain injury owing to its simplicity, non-invasiveness, safety, and patient tolerability. Different forms of remote ischemic conditioning exhibit distinct intervention patterns, timing, and application range. Mechanistically, remote ischemic conditioning can exert neuroprotective effects by activating the Notch1/phosphatidylinositol 3-kinase/Akt signaling pathway, improving cerebral perfusion, suppressing neuroinflammation, inhibiting cell apoptosis, activating autophagy, and promoting neural regeneration. While remote ischemic conditioning has shown potential in improving stroke outcomes, its full clinical translation has not yet been achieved.

关键词： Akt apoptosis autophagy cerebral perfusion cerebral vascular stenosis clinical transformation hemorrhagic stroke ischemic stroke neuroinflammation neuroprotection Notch1 PI3K remote ischemic conditioning stroke

Cortico-striatal gamma oscillations are modulated by dopamine D3 receptors in dyskinetic rats

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Neural Regeneration Research 2025年第4期20卷 1164-1177页

作者： Pengfei Wang Yuewei Bi Min li Jiazhi Chen Zhuyong Wang Huantao wen Ming Zhou Minjie Luo Wangming Zhang Neurosurgery Center Department of Pediatric NeurosurgeryGuangdong Provincial Key Laboratory on Brain Function Repair and RegenerationZhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina

Long-term levodopa administration can lead to the development of levodopa-induced *** oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced ***,studies have reported increased oscillation power in cases of levodopa-induced ***,little is known about how the other electrophysiological parameters of gamma oscillations are altered in levodopa-induced ***,the role of the dopamine D3 receptor,which is implicated in levodopa-induced dyskinesia,in movement disorder-related changes in neural oscillations is *** found that the cortico-striatal functional connectivity of beta oscillations was enhanced in a model of Parkinson’s ***,levodopa application enhanced cortical gamma oscillations in cortico-striatal projections and cortical gamma aperiodic components,as well as bidirectional primary motor cortex(M1)↔dorsolateral striatum gamma *** of PD128907(a selective dopamine D3 receptor agonist)induced dyskinesia and excessive gamma oscillations with a bidirectional M1↔dorsolateral striatum ***,administration of PG01037(a selective dopamine D3 receptor antagonist)attenuated dyskinesia,suppressed gamma oscillations and cortical gamma aperiodic components,and decreased gamma causality in the M1→dorsolateral striatum *** findings suggest that the dopamine D3 receptor plays a role in dyskinesia-related oscillatory activity,and that it has potential as a therapeutic target for levodopa-induced dyskinesia.

关键词： aperiodic components dopamine D3 receptor dorsolateral striatum functional connectivity gamma oscillations levodopa-induced-dyskinesia local field potentials neuromodulation Parkinson’s disease primary motor cortex

Loss-of-function mutations of microRNA-142-3p promote ASH1L expression to induce immune evasion and hepatocellular carcinoma progression

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World Journal of Gastroenterology 2025年第1期31卷 126-145页

作者： Xing-Hui Yu Yan Xie Jian Yu Kun-Ning Zhang Zhou-Bo Guo Di Wang Zhao-Xian li Wei-Qi Zhang Yu-Ying Tan li Zhang wen-Tao Jiang School of Medicine Nankai UniversityTianjin 300192China Tianjin Key Laboratory of Molecular Diagnosis and Treatment of liver Cancer Tianjin First Center HospitalTianjin 300192China Department of liver Transplantation Tianjin First Center HospitalTianjin 300192China First Central Clinical School Tianjin Medical UniversityTianjin 300192China

BACKGROUND Hepatocellular carcinoma(HCC)has been a pervasive malignancy throughout the world with elevated *** therapeutic targets are beneficial to treat and predict the ***,the exact molecular mechanisms leading to the progression of HCC are still *** has shown that the microRNA-142-3p level decreases in HCC,whereas bioinformatics analysis of the cancer genome atlas database shows the ASH1L expression increased among liver tumor *** this paper,we will explore the effects and mechanisms of microRNA-142-3p and ASH1L affect the prognosis of HCC patients and HCC cell bioactivity,and the association between *** To investigate the effects and mechanisms of microRNA-142-3p and ASH1L on the HCC cell bioactivity and prognosis of HCC *** In this study,we grouped HCC patients according to their immunohistochemistry results of ASH1L with pathological tissues,and retrospectively analyzed the prognosis of HCC ***,explored the roles and mechanisms of microRNA-142-3p and ASH1L by cellular and animal experiments,which involved the following experimental methods:Immunohistochemical staining,western blot,quantitative real-time-polymerase chain reaction,flow cytometric analysis,tumor xenografts in nude mice,*** statistical methods involved in this study contained t-test,one-way analysis of variance,theχ^(2)test,the Kaplan-Meier approach and the log-rank *** In this study,we found that HCC patients with high expression of ASH1L possess a more recurrence rate as well as a decreased overall survival ***1L promotes the tumorigenicity of HCC and microRNA-142-3p exhibits reduced expression in HCC tissues and interacts with ASH1L through targeting the ASH1L 3′untranslated ***,microRNA-142-3p promotes apoptosis and inhibits proliferation,invasion,and migration of HCC cell lines in vitro via *** the exploration mechanism,we found ASH1L may promote an immunosuppressive mi

关键词： Hepatocellular carcinoma MicroRNA-142-3p ASH1L Immune evasion Tumor immune microenvironment Apoptosis

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灰口铸铁气缸套内表面激光热处理的研究

金属热处理 1987年第11期 24-27页

作者：周家瑾金秦周振文韩景岩东继光贺雯靖李成芳西安内燃机配件厂研究所北京市机电研究院激光加工中心西安交通大学强度研究所

本文论述了灰口铸铁气缸套内表面的激光热处理。内表面采用扫描速度20mm/s,离焦量27.5mm,功率1000W,以螺纹或网纹的扫描形式进行激光强化热处理,可获得高度弥散的马氏体、渗碳体和残留奥氏体组织,提高缸套的强度和相对耐磨性,减小变形,... 详细信息

本文论述了灰口铸铁气缸套内表面的激光热处理。内表面采用扫描速度20mm/s,离焦量27.5mm,功率1000W,以螺纹或网纹的扫描形式进行激光强化热处理,可获得高度弥散的马氏体、渗碳体和残留奥氏体组织,提高缸套的强度和相对耐磨性,减小变形,并可改善与各种环的配副性能。表面激光热处理是改善灰口铸铁工件表面性能的有效方法。

关键词：激光热处理灰口铸铁气缸套内表面配副性

红金消结胶囊联合他莫昔芬治疗乳腺增生症的临床疗效研究

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临床合理用药杂志 2012年第6期5卷 14-15页

作者：何江侯令密程文丽川北医学院附属医院普外三科四川省南充市637000

目的观察红金消结胶囊联合他莫昔芬治疗乳腺增生症的疗效。方法治疗组(108例)采用红金消结胶囊联合他莫昔芬治疗乳腺增生症;对照组(95例)采用乳癖消治疗乳腺增生症;1个月经周期为1个疗程,使用1～3个疗程观察疗效。结果治疗组的有效率和... 详细信息

目的观察红金消结胶囊联合他莫昔芬治疗乳腺增生症的疗效。方法治疗组(108例)采用红金消结胶囊联合他莫昔芬治疗乳腺增生症;对照组(95例)采用乳癖消治疗乳腺增生症;1个月经周期为1个疗程,使用1～3个疗程观察疗效。结果治疗组的有效率和治愈率分别为:97.22%和78.70%;对照组的有效率和治愈率分别为86.32%和64.21%;两组比较差异有统计学意义(P<0.05)。结论红金消结胶囊联合他莫昔芬治疗乳腺增生有较好的疗效,无明显不良反应发生。

关键词：乳腺增生症红金消结胶囊他莫昔芬

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微型计算机软磁盘的保护与使用技术

安庆师范学院学报（自然科学版） 2001年第2期7卷 57-59页

作者：任广永陈文莉安庆师范学院数学计算机系安徽安庆246000

本节介绍软磁盘的正确使用及保护方法 ,并结合实际提出计算机运行中数据读取出错的一些新看法。

关键词：软磁盘格式化计算机病毒微型计算机保护方法数据读取操作

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家兔頸动脉窦区化学感受性机能的研究

生理学报 1965年第3期28卷 328-336页

作者：邓希賢莫正文李天麟中国医学科学院实验医学研究所生理学系中国医学科学院劳动卫生环境卫生营养卫生研究所北京

(一)用交叉循环法灌流家兔两侧的隔离頸动脉窦。当供血动物呼吸純氮时,受血动物的血压上升,呼吸增强。切除受血动物頸动脉窦的神經支配后,上述反应不再出現。 (二)在猫的实驗中,小量乙酰胆碱或二硝基邻甲酚注射到总頸动脉内,一般便能引... 详细信息

(一)用交叉循环法灌流家兔两侧的隔离頸动脉窦。当供血动物呼吸純氮时,受血动物的血压上升,呼吸增强。切除受血动物頸动脉窦的神經支配后,上述反应不再出現。 (二)在猫的实驗中,小量乙酰胆碱或二硝基邻甲酚注射到总頸动脉内,一般便能引起血压上升和呼吸增强反射。另一方面,需要較大剂量才能在家兔身上获得同样的反射性反应。 (三)猫在麻醉情况下,冷阻断窦神經傳入冲动,在失血前引起呼吸抑制、血压上升;在失血后引起呼吸抑制、血压下降。在同样情况下,冷阻断家兔窦神經傳入冲动时,沒有观察到类似的反应。 (四)討論了家兔和猫頸动脉窦区化学感受性机能的某些特征。

关键词：化学感受器邻甲酚动物动脉内注射家兔性机能