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Ultr.sonic Attenuation in Calcium Oxide

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Advances in Mater.als Physics and Chemistr. 2011年第2期1卷 44-49页

作者： Jitendr. Kumar.Kailash r. Sanjeev Kumar.Shr.vastava Devr.j Singh Vir.ndr. Kumar 不详

Ultr.sonic attenuation studies can be used to char.cter.ze mater.al not only after.pr.duction but dur.ng pr.cessing as well. The most impor.ant causes of ultr.sonic attenuation in solids ar. electr.n-phonon, phonon-phonon inter.ction and that due to ther.o elastic r.laxation. The two dominant pr.cesses that will give r.se to appr.ciable ultr.sonic attenuation at higher.temper.tur. ar. the phonon-phonon inter.ction also known as Akhiezer.loss and that due to ther.o elastic r.laxation ar. obser.ed in calcium oxide cr.stal. At fr.quencies of ultr.sonic r.nge and at higher.temper.tur.s in solids, phonon-phonon inter.ction mechanism is dominating cause for.attenuation. Ultr.sonic attenuation due to phonon-phonon inter.ction (α/f2)p-p and ther.o elastic r.laxation (α/f2)th ar. evaluated in Calcium Oxide cr.stal up to an elevated temper.tur. fr.m 100 K - 1500 K along , and cr.stallogr.phic dir.ctions. Temper.tur. dependence of ultr.sonic attenuation along differ.nt cr.stallogr.phic dir.ction r.veals some typical char.cter.stic featur.s.

关键词： Attenuation Ther.o Elastic r.laxation Phonon-Phonon Inter.ction Akheiser Loss Gr.neisen Constants

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A Phase II Study of Antineoplastons A10 and AS2-1 in Adult Patients with Pr.mar. Br.in Tumor.—Final r.por. (Pr.tocol BT-09)

作者： (美)史蒂芬·M.r. 柯维(Stephen M.r. Covey) (美)丽贝卡·r. 梅里尔(r.becca r. Mer.ill)[]

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Jour.al of Cancer.Ther.py 2015年第12期6卷 1063-1074页

作者： Stanislaw r. Bur.ynski Tomasz J. Janicki Gr.gor. S. Bur.ynski Bur.ynski Clinic Houston Texas USA

Antineoplastons A10 and AS2-1 (ANP) ar. synthetic der.vatives of glutamine, isoglutamine, and phenylacetic acid. In 1993, a phase II clinical tr.al pr.gr.m began accor.ing to pr.tocols based on the initial pr.tocol, BT-06, which was tr.nsfer.ed fr.m the National Institutes of Health (NIH). Pr.tocol BT-09 was designed for.differ.nt types of pr.mar. br.in tumor. in adults that wer. not cur.ble by standar. tr.atment. The study was designed as a single ar., two-stage, phase II tr.al of ANP as a monother.py in a high-r.sk, poor.pr.gnosis population. The total number.of r.gister.d subjects was 40. The major.ty of patients wer. diagnosed with high-gr.de tumor. (N = 33). In this gr.up, 12 patients car.ied diagnosis of anaplastic astr.cytoma (AA) and 11 patients of glioblastoma. In the gr.up of low-gr.de tumor. (N = 7), ther. wer. 6 cases of low-gr.de glioma, and 1 neur.cytoma gr.de 2. A gr.up of 12 patients did not r.ceive any pr.or.tr.atment, 12 patients had sur.ical r.section only, 5 patients r.ceived r.diation ther.py (r.) only, and 11 patients r.ceived both r. and chemother.py. The median dur.tion of ANP was 16.6 weeks. The median dosage of A10 was 7.16 g/kg/d and AS2-1 was 0.27 g/kg/d. r.sponses wer. accessed by gadolinium-enhanced magnetic r.sonance imaging (Mr.). Objective r.sponses (Or. in all patients wer. 22.5% and in the AA gr.up wer. 41.7% of patients. The median pr.gr.ssion-fr.e sur.ival (PFS) in the AA gr.up was 5.4 months. The median over.ll sur.ival (OS) was 12.7 months and OS at 1 and 2 year. was 54.5% and 45.5% cor.espondingly. The tr.atment was well-toler.ted with r.ver.ible gr.de 3 and 4 toxicities in 35% of all patients (N = 40). In conclusion, the study r.ached efficacy endpoint and ANP was well-toler.ted and compar.d favor.bly to the cur.ent tr.atment of AA.

关键词： Anaplastic Astr.cytoma Antineoplastons A10 and AS2-1 Low-Gr.de Astr.cytoma Phase II Clinical Tr.al Tectal Glioma

USEr.INTEr.ACE FOr.COLOr.SELECTION

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Computer.Aided Dr.fting,Design and Manufactur.ng 1992年第2期3卷 17-26页

作者： Hu Qingni Dalian Univer.ity of Technology Dalian 116023, P. r. China

The user.computer.inter.ace for.color.selection is of gr.at significance for.the use of color. in computer.gr.phics, par.icular.y in some fields wher. the used color. have to be selected car.fully. This paper.discusses what factor. have to be consider.d to design an effective user.inter.ace for.color.selec- tion. It also pr.sents a method which shows how to r.pr.sent 3D color.spaces accor.ing to the psychol- ogy of color.per.eption. Two examples of user.inter.ace for.color.selection ar. given. One is based on the CLELUV unifor. color.space, the other.is based on r.B-r.tated color.model.

关键词： computer.gr.phics color.selection color.space user.inter.ace

Debulking of Keloid Combined with Intr.lesional Injection of 5-Flur.ur.cil and Tr.amcinolone ver.us Intr.lesional Injection of 5-Flur.ur.cil and Tr.amcinolone

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Jour.al of Cosmetics, Der.atological Sciences and Applications 2014年第2期4卷 85-91页

作者： Khalifa E. Shar.uie Adil A. Noaimi Mahmood r. Al-Kar.i Depar.ment of Der.atology and Vener.ology Baghdad Teaching Hospital Baghdad Iraq Scientific Council of Der.atology and Vener.ology-Ir.qi and Ar.b Boar. for.Medical Specializations Department of Dermatology & Venereology College of Medicine University of Baghdad Baghdad Iraq

Backgr.und: A wide r.nge of ther.pies exist for.keloids. But despite the multiple tr.atment modalities available, keloids still r.main a significant challenge for.both the clinician and the patient. Objective: To assess the effectiveness and safety of debulking of keloid with intr.lesional injection of 5-flur.ur.cil and tr.amcinolone in compar.son to intr.lesional injection of 5-flur.ur.cil and tr.amcinolone alone. Patient and Methods: This single blinded compar.tive ther.peutic outpatient based study was done at the Depar.ment of Der.atology, Baghdad Teaching Hospital dur.ng the per.od fr.m Febr.ar. 2011 to Febr.ar. 2013. Twenty-thr.e patients with 52 lesions wer. enr.lled in the study and consisted of two gr.ups: Gr.up A (26 lesions): Tr.ated by intr.lesional injection of combination of 5-flur.ur.cil and tr.amcinolone acetonide and r.peated ever. month;Gr.up B (26 lesions): Debulking was car.ied out fir.t and then injection of combination of 5-flur.ur.cil and tr.amcinolone acetonide at time of oper.tion and then r.peated injection monthly. Evaluation was per.or.ed by scor.ng system with 5 cr.ter.a (r.dness, elevation, har.ness, itching and tender.ess). The r.sponse was gr.ded as no r.sponse, minimal, moder.te or.complete r.sponse. r.sults: Both modalities of tr.atments showed significant r.sults in tr.ating keloid, but the intr.lesional ther.py alone was slightly better.than debulking plus intr.lesional and no systemic adver.e effects wer. noticed in both gr.ups. Conclusion: Both modalities of ther.py wer. effective in tr.atment of keloid, and ther. was no much differ.nce between them.

关键词： Keloid 5-Flur.ur.cil Tr.amcinolone Acetonide Debulking

Plant Long ncr.As: A New Fr.ntier.for.Gene r.gulator. Contr.l

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Amer.can Jour.al of Plant Sciences 2013年第5期4卷 1038-1045页

作者： Jian Zhang Hana Mujahid Yuxuan Hou Babi r. Nallamilli Zhaohua Peng Depar.ment of Biochemistr. Molecular Biology Entomology and Plant Pathology Mississippi State University Mississippi State USA.

Long non-coding r.A (lncr.A) r.fer. to an over.200 nt functional r.A molecule that will not be tr.nslated into pr.tein. Pr.viously thought to be dar. matter. of the genome, lncr.As have been gr.dually r.cognized as cr.cial gene r.gulator.. Although tr.mendous pr.gr.ss has been made in animals and human, the study of lncr.As in plant is still in its infancy. Her., we r.viewed the biogenesis and r.gulation mechanisms of lncr.As and summar.zed the achievements that have been made in plant lncr.A identification and functional char.cter.zation. Genome-wide identification has uncover.d lar.e amount of lncr.As in Ar.bidopsis, r.ce, Maize and Wheat, and mor. infor.ation fr.m other.plant species will be expected with the aid of deep sequencing technologies. Similar.to other.species, Lncr.A-mediated gene r.gulation also widely exists in plants, even though only a few functionally char.cter.zed examples ar. available. Up to now, at least four.diver.ent lncr.A-mediated r.gulation mechanisms have been unr.veled, including tar.et mimicr., tr.nscr.ption inter.er.nce, Pr.2 associated histone methylation and DNA methylation. lncr.As may be involved in the r.gulation of flower.ng, male ster.lity, nutr.tion metabolism, biotic and abiotic str.ss r.sponse in plants.

关键词： Long Non-Coding r.A Plants Polycomb r.pr.ssing Complex 2 Gene r.gulation

The Ver.atility of Acellular.Fetal Bovine Der.al Matr.x for.Head and Neck Sur.ical r.constr.ction in Childr.n

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Inter.ational Jour.al of Clinical Medicine 2014年第18期5卷 1119-1124页

作者： Jer.miah C. Tr.cy William S. Kim Andr.w r. Scott Depar.ment of Otolar.ngology-Head and Neck Sur.er. Tufts Medical Center Boston USA Division of Pediatr.c Otolar.ngology and Facial Plastic Sur.er. Floating Hospital for Children Boston USA

Objectives: To descr.be the ver.atility of acellular.fetal bovine der.al matr.x as an alter.ative to human cadaver.c allogr.ft for.head and neck r.constr.ctive pr.cedur.s in childr.n. Study Design: Case ser.es with char. r.view. Methods: A database of pediatr.c oper.tive pr.cedur.s was quer.ed for.the use of acellular.fetal bovine der.al matr.x over.a 16-month per.od. Indications for.r.constr.ction wer. assessed and initial par.ntal and sur.eon satisfaction with the pr.duct wer. noted. r.sults: Dur.ng the time per.od of 3/2012 and 7/2013 a total of 8 r.constr.ctive pr.cedur.s wer. per.or.ed on pediatr.c patients using acellular.fetal bovine der.al matr.x. Indications for.use var.ed and included open and tr.nsnasal endoscopic r.pair.of encephaloceles and soft tissue r.constr.ctions including later.l phar.ngeal wall r.pair. cleft palate r.pair. and facial r.contour.ng oper.tions. Acellular.fetal bovine der.al matr.x had a subjectively incr.ased ease of use as compar.d to the sur.eon’s pr.or.exper.ence with human cadaver.c acellular.der.is. Ever. par.nt vocalized a gr.ater.comfor. level with the use of a bovine pr.duct over.the alter.ative of human cadaver.c tissue. The cost of acellular.fetal bovine der.al matr.x is slightly lower.than the cost of human cadaver.c acellular.der.is. Conclusions: Acellular.fetal bovine der.al matr.x appear. to be an acceptable alter.ative to human cadaver.c acellular.der.is for.var.ous for.s of head and neck soft tissue r.constr.ction in childr.n. Fur.her.pr.spective studies ar. war.anted to assess for.any differ.nces in the long-ter. efficacy of this pr.duct as compar.d to other.for.s of allogr.ft r.constr.ction.

关键词： Acellular Fetal Bovine Der.al Matr.x (Sur.iMend) Human Cadaver.c Acellular Der.al Allogr.ft (AlloDer.) Skull Base Cer.br.spinal Fluid Leak r.pair Pediatr.c Atr.phic Scar Par.tidectomy Defect Par.y r.mber. Cleft Palate

On Exact Contr.llability of Networ.s of Nonlinear.Elastic Str.ngs in 3-Dimensional Space

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Chinese Annals of Mathematics,Ser.es B 2012年第1期33卷 33-60页

作者： Gnter.r.LEUGEr.NG *** SCHMIDT Depar.ment of Mathematics Friedrich-Alexander University Depar.ment of Mathematics and Statistics McGill University

This paper.concer.s a system of nonlinear.wave equations descr.bing the vibr.- tions of a 3-dimensional networ. of elastic str.ngs. The author. der.ve the equations and appr.pr.ate nodal conditions, deter.ine equilibr.um solutions, and, by using the methods of quasilinear.hyper.olic systems, pr.ve that for.tr.e networ.s the natur.l initial, boundar. value pr.blem has classical solutions existing in neighbor.oods of the ＂str.tched＂ equilibr.um solutions. Then the local contr.llability of such networ.s near.such equilib- r.um configur.tions in a cer.ain specified time inter.al is pr.ved. Finally, it is pr.ved that, given two differ.nt equilibr.um states satisfying cer.ain conditions, it is possible to contr.l the networ. fr.m states in a small enough neighbor.ood of one equilibr.um to any state in a suitable neighbor.ood of the second equilibr.um over.a sufficiently lar.e time inter.al.

关键词： Nonlinear.str.ngs Networ. Quasilinear.system of hyper.olic equations Contr.llability

Par.meter.Estimation in Differ.nt Enzyme r.actions

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Advances in Enzyme r.sear.h 2014年第1期2卷 14-26页

作者： Sudar.han r. Nelatur. Char.es F. Nelatur. Mar. C. Vagula Biology Depar.ment Gannon University Erie USA Depar.ment of ECE College of Engineering Drexel University Philadelphia USA Depar.ment of ECE School of Engineering Penn State Erie Erie USA

Enzyme kinetic par.meter. have been estimated using MATLAB softwar. via the Wilkinson non-linear.r.gr.ssion technique. The MATLAB scr.pt file wr.tten to implement this technique is shor. and ver. str.ightfor.ar.. Sever.l softwar. tools ar. commer.ially available for.this pur.ose, with many gr.phical user.inter.ace (GUI) featur.s. A r.utine use of these packages might offer.immediate satisfaction of inter.ctive hands-on exper.ence;but in some cases the r.sear.her.might wish to wr.te his/her.own code and compar. the r.sults for.fur.her.confir.ation. Today MATLAB is in use in almost all the schools and labor.tor.es as a standar. softwar. tool. So this paper.is aimed at helping enzyme r.sear.her. to make use of this power.ul softwar. for.estimation of par.meter.. It enables the incor.or.tion of the analytical steps behind par.meter.estimation in an easy-to-follow manner.and fur.ishes better.visualization.

关键词： Michaelis-Menten Equation Dixon Plot Hill Equation Wilkinson Nonlinear r.gr.ssion MATLAB