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Vascular endothelial growth factor/connective tissue growth factor and proteomic analysis of aqueous humor after intravitreal conbercept for proliferative diabetes retinopathy

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International Journal of Ophthalmology(English edition) 2024年第10期17卷 1816-1827页

作者： Hou-Shuo Li Xiao Lyu Ao Rong Yan-Long Bi wei Xu hong-ping Cui Department of Ophthalmology Tongji HospitalSchool of MedicineTongji UniversityShanghai 200065China Department of Ophthalmology Shanghai East HospitalSchool of MedicineTongji UniversityShanghai 200120China

AIM:To investigate the role of connective tissue growth factor(CTGF)and vascular endothelial growth factor(VEGF)in the protein profile of the aqueous humor in patients with proliferative diabetic retinopathy(PDR)following intravitreal injection of ***:This study included 72 PDR patients and 8 cataract patients as *** patients were divided into 3 groups according to the intervals of 3,5,and 7d between intravitreal conbercept(IVC,0.5 mg/0.05 mL)injection and pars plana vitrectomy(PPV)*** humor samples were collected before and after IVC and PPV for VEGF and CTGF levels detected with enzyme-linked immunosorbent assay(ELISA).The differential proteomics of 10 patients who underwent PPV surgery 5d after IVC and 8 normal controls was studied,Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analysis were performed on the data,and the protein interaction network of 23 differential proteins was ***:Post-IVC,VEGF levels decreased and CTGF levels increased significantly in aqueous humor,with the CTGF/VEGF ratio rising significantly at all *** chromatography tandem mass spectrometry(LC-MS/MS)identified differentially expressed proteins between preand post-IVC *** and KEGG analyses revealed involvement in immune response,stress response,complement and coagulation cascades,ferroptosis,and PPAR signaling *** analysis highlighted key proteins like APOA1,C3,and transferrin(TF).ELISA assay confirmed the differential expression of proteins such as HBA1,SERPINA1,COL1A1,and ACTB,with significant changes in the IVC ***:The study demonstrates that IVC effectively reduces VEGF levels while increasing CTGF levels,thereby modifying the CTGF/VEGF ratio,and IVC significantly alters the protein profile in the aqueous humor of patients with *** analysis reveals that these changes are associated with critical biological pathways and protein interactions involved in immune respons

关键词： proliferative diabetic retinopathy conbercept vascular endothelial growth factor connective tissue growth factor proteomics

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Improving Thermal-oxidative Aging Resistance of Styrene-butadiene Rubber by Antioxidant Loaded Silica Aerogel

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Chinese Journal of Polymer Science 2024年第8期42卷 1198-1209页

作者： Xue-Fei ping Yu Wang Lu Liu Fu-Yong Liu hong-wei He Pi Wang Wen-Wen Yu Qiang Zheng College of Materials Science and Engineering Taiyuan University of TechnologyTaiyuan 030024China Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering Taiyuan 030032China Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringZhejiang UniversityHangzhou 310058China

The antioxidant N-isopropyl-N'-phenyl-p-phenylenediamine(4010NA)was dissolved in ethanol and impregnated into silica aerogel(SAG)via vacuum-pressure cycles,yielding composite particles(A-N)with enhanced sustained-release and reinforcing *** effect of A-N on the mechanical properties and thermal-oxidative aging resistance of styrene-butadiene rubber(SBR)vulcanizates was *** and BET assessments indicated that the loading efficiency of 4010NA in SAG reached 14.26%within ethanol's solu bility *** A-N into SBR vulcanizates significantly elevated tensile strength by 17.5%and elongation at break by 41.9%over those with fumed silica and ***,A-N notably enhanced the thermal-oxidative aging resistance of *** aging for 96 h at 100℃,the tensile strength and elongation at break of SBR with A-N sustained 70.09%and 58.61%of their initial values,respectively,with the retention rate of elongation at break being 62.8%higher than that of SBR with fumed silica and free *** study revealed that A-N composite particles significantly inhibited the crosslinking in SBR's molecular chains,reducing hardening and embrittlement during later thermal-oxidative aging stages.

关键词： Styrene-butadiene rubber Silica aerogel Loading modification Thermal-oxidative aging

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Analysis of China's Electricity Price and Electricity Burden of Basic Industries under the Carbon Peak Target before 2030

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CSEE Journal of Power and Energy Systems 2024年第2期10卷 481-491页

作者： Yue Qiu Suyang Zhou wei Gu Xiao-ping Zhang School of Electrical Engineering Southeast UniversityNanjingChina School of Electronic Electrical and System EngineeringUniversity of BirminghamU.K.

The Chinese government is deepening reformation of electricity prices during the 14th Five Year Plan period and has set a carbon emission reduction target of reaching carbon peak before *** this context,will the carbon emission target influence electricity pricing and will electricity price influence competitiveness of Chinese main industries are two questions needing to be *** paper compares China's electricity price level with the selected major countries in the world,and four typical industries are selected to evaluate their electricity burden ***,the correlation between residential electricity price and industrial electricity price and the influencing factors is analyzed,from the perspectives of scale,structure and *** to the model obtained by regression analysis,the electricity price level and corresponding residential and industrial electricity burden in 2025 and 2030 are *** Terms-Electricity burden,industrial electricity price,regression analysis,residential electricity price.

关键词： Electricity burden industrial electricity price regression analysis residential electricity price

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Passive Ubiquitous Perception System Oriented to Aerospace-Ground Internet of Things Communication

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Journal of Communications and Information Networks 2024年第3期9卷 277-285页

作者： hong hong wei Gong Qiwei Wang School of Electronic and Optical Engineering Nanjing University of Science and TechnologyNanjing 210094China School of Computer Science and Technology University of Science and Technology of ChinaHefei 230027China

Because the aerospace-ground Internet no longer relies on deploying infrastructure such as base stations,it has the advantage of all-weather full coverage services that traditional terrestrial networks do not ***,the traditional global navigation satellite system does not support communication *** newly developing aerospace network system is still in the construction stage,and there is no applicable solution *** communication technology is an important method to solve the contradiction between the low battery capacity of the Internet of things(IoT)node and the high energy consumption of *** is the development trend of the ***,the current passive technology based on Wi-Fi and other signals cannot achieve arbitrary communication due to the excitation signal acquisition *** solve the above two major problems,this paper proposes a passive system design for aerospace-ground IoT *** system can use the global navigation signal as excitation signal for backscatter *** the global navigation signal has the characteristics of all-weather and full coverage,this design solves the carrier acquisition problem in previous *** addition,this paper also proposes a low-power signal detection technology that can detect navigation signals with high precision on passive *** evaluate system performance through simulation *** experimental results show that the backscatter system based on global navigation satellite signals can realize efficient communication of IoT nodes.

关键词： backscatter passive IoT global navigation satellite system aerospace network

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Editorial:special issue on analysis and control of complex systems in honor of the 90th birthday of Professor Huashu Qin

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Control Theory and Technology 2024年第3期22卷 343-344页

作者： Yiguang hong Shengwei Mei ping Yang Department of Control Science and Engineering Tongji UniversityShanghai200092China Shanghai Research Institute for Intelligent Autonomous Systems Tongji UniversityShanghai200092China Department of Electrical Engineering and Applied Electronics Technology Tsinghua UniversityBeijing100084China School of Electric Power South China University of TechnologyGuangzhou510640GuangdongChina

It is our great pleasure to organize this special issue in Control Theory and Technology in honor of the 90th birthday of Professor Huashu *** is one of the pioneers in control theory and applications in China,and has made many truly outstanding contributions to the field including nonlinear dynamics and control,intelligent control,robotics and complex *** is no surprise that she was selected as a representative introduced significantly in“Women in Control”of IEEE Control Systems Magazine.

关键词： control honor analysis

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Low Surface Brightness Galaxies from BASS+MzLS with Machine Learning

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Research in Astronomy and Astrophysics 2024年第5期24卷 185-197页

作者： Peng-Liang Du wei Du Bing-Qing Zhang Zhen-ping Yi Min He hong Wu Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China School of Mechanical Electrical and Information EngineeringShandong UniversityWeihai 264209China

From ∼5000 deg^(2) of the combination of the Beijing–Arizona Sky Survey and Mayall z-band Legacy Survey which is also the northern sky region of the Dark Energy Spectroscopic Instrument (DESI) Legacy Imaging Surveys, we selected a sample of 31,825 candidates of low surface brightness galaxies (LSBGs) with the mean effective surface brightness 24.2 0.60) LSBGs. The blue LSBGs appear spiral, disk or irregular while the red LSBGs are spheroidal or elliptical and spatially clustered. This trend shows that the color has a strong correlation with galaxy morphology for LSBGs. In the spatial distribution, the blue LSBGs are more uniformly distributed while the red ones are highly clustered, indicating that red LSBGs preferentially populate a denser environment than the blue LSBGs. Besides, both populations have a consistent distribution of ellipticity (median ∈∼ 0.3), half-light radius (median r_(eff) ∼ 4″) and Sérsic index (median n=1), implying the dominance of the full sample by the round and disk galaxies. This sample has definitely extended the studies of LSBGs to a regime of lower surface brightness, fainter magnitude and broader other properties than the previously Sloan Digital Sky Survey-based samples.

关键词： catalogs-galaxies fundamental parameters-galaxies statistics-techniques photometric

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Remaining Useful Life Prediction Method for Multi-Component System Considering Maintenance:Subsea Christmas Tree System as A Case Study

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China Ocean Engineering 2024年第2期38卷 198-209页

作者： WU Qi-bing CAI Bao-ping FAN hong-yan WANG Guan-nan RAO Xi GE weifeng SHAO Xiao-yan LIU Yong-hong CNOOC Safety Technology Services Co. Ltd.Tianjin 300456China College of Mechanical and Electronic Engineering China University of PetroleumQingdao 266580China CNOOC EnerTech Safety&Environmental Protection BranchTianjin 300456China

Maintenance is an important technical measure to maintain and restore the performance status of equipment and ensure the safety of the production process in industrial production,and is an indispensable part of prediction and health ***,most of the existing remaining useful life(RUL)prediction methods assume that there is no maintenance or only perfect maintenance during the whole life cycle;thus,the predicted RUL value of the system is obviously lower than its actual operating *** complex environment of the system further increases the difficulty of maintenance,and its maintenance nodes and maintenance degree are limited by the construction period and working conditions,which increases the difficulty of RUL *** RUL prediction method for a multi-omponent system based on the Wiener process considering maintenance is *** performance degradation model of components is established by a dynamic Bayesian network as the initial model,which solves the uncertainty of insufficient data *** on the experience of experts,the degree of degradation is divided according to Poisson process simulation random failure,and different maintenance strategies are used to estimate a variety of condition maintenance *** example of a subsea tree system is given to verify the effectiveness of the proposed method.

关键词： remaining useful life Wiener process dynamic Bayesian networks maintenance subsea Christmas tree system

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Effect of oxide inclusions on MnS precipitates and tensile mechanical property of high-strength low-alloy steel

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Journal of Iron and Steel Research International 2024年第5期31卷 1210-1220页

作者： Xiao-yong Gao hong wei Li-feng Zhang School of Mechanical Engineering Yanshan UniversityQinhuangdao066004HebeiChina School of Materials Science and Engineering Yanshan UniversityQinhuangdao066004HebeiChina School of Mechanical and Materials Engineering North China University of TechnologyBeijing100144China

The key role of oxide inclusions on the microstructure and mechanical property of a high-strength low-alloy steel was *** field emission scanning electron microscope equipped with energy-dispersive spectrometry was used to characterize MnS *** inclusions play an important role in the shape control of MnS *** oxides fovored to decrease the size and the aspect ratio of MnS *** less oxide inclusions in the steel,approximately over 16.7%MnS precipitates were with aspect ratio a>5 and pure MnS precipitates accounted for 75.9%in ***,with more oxide inclusions in the steel,only 7.4%MnS precipitates were with a>5 and pure MnS precipitates accounted for 60.1%in *** of MnS by oxide inclusions improved the strength and inhibited the *** oxide inclusions in the steel increased the yield strength and tensile strength of the steel in both longitudinal and transverse directions,and lowered the anisotropy of the mechanical property.

关键词： High-strength low-alloy steel MnS Oxide inclusion Mechanical property Anisotropy

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Does Green Food Certification promote agri-food export quality?Evidence from China

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Journal of Integrative Agriculture 2024年第3期23卷 1061-1074页

作者： ping wei hongman Liu Chaokai Xu Shibin Wen College of Economics and Management China Agricultural UniversityBeijing 100083China School of Public Affairs Zhejiang UniversityHangzhou 310058China

The construction of a food certification system plays a vital role in upgrading export quality, which previous studies have largely overlooked. We match China's industry-level data of Green Food Certification with its HS6-digit export data of agri-food products to quantify the impact of Green Food Certification on export quality. We identify the significant and positive effect of Green Food Certification on export quality. The 2SLS estimation based on instrumental variables and a range of robustness checks confirm the validity and robustness of the benchmark conclusions. Further analysis discloses that Green Food Certification improves export quality by raising agricultural production efficiency and brand premiums. Heterogeneity analysis shows that the effect of Green Food Certification varies across regions, notably improving the quality of agri-food products exported to developed regions and regions with high levels of import supervision. Furthermore, among various product types, Green Food Certification significantly improves the export quality of primary products and products vulnerable to non-tariff measures. The above findings could guide the future development of agri-food quality certification systems, potentially leading to a transformation and promotion of the agri-food trade.

关键词： Green Food Certification agri-food products green transformation export quality food labeling

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Impact of volcanism on the formation and hydrocarbon generation of organic-rich shale in the Jiyang Depression, Bohai Bay Basin, China

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Petroleum Science 2024年第3期21卷 1539-1551页

作者： Jia-hong Gao Xin-ping Liang Zhi-Jun Jin Quan-You Liu Chang-Rong Li Xiao-wei Huang Ju-Ye Shi Peng Li State Key Laboratory of Shale Oil and Gas Enrichment Mechanisms and Efficient Development Institute of EnergyPeking University Petroleum Exploration and Production Research Institute SINOPECBeijing100871 China School of Energy Resources China University of Geosciences Beijing100083 China

Globally,most organic-rich shales are deposited with volcanic ash *** ash,a source for many sedimentary basins,can affect the sedimentary water environment,alter the primary productivity,and preserve the organic matter(OM)through physical,chemical,and biological *** an increasing number of breakthroughs in shale oil exploration in the Bohai Bay Basin in recent years,less attention has been paid to the crucial role of volcanic impact especially its influence on the OM enrichment and hydrocarbon ***,we studied the petrology,mineralogy,and geochemical characteristics of the organic-rich shale in the upper submember of the fourth member(Es_(4)^(1))and the lower submember of the third member(Es_(3)^(3))of the Shahejie Formation,aiming to better understand the volcanic impact on organic-rich shale *** results show that total organic carbon is higher in the upper shale intervals rich in volcanic ash with enriched light rare earth elements and moderate Eu *** indicates that volcanism promoted OM formation before or after the *** positive correlation between Eu/Eu*and Post-Archean Australian Shale indicates hydrothermal activity before the volcanic *** plane graph of the hydrocarbon-generating intensity(S1+S2)suggests that the heat released by volcanism promoted hydrocarbon ***,the nutrients carried by volcanic ash promoted biological blooms during Es_(4)^(1 )and Es_(3)^(3) deposition,yielding a high primary *** blooms consume large amounts of oxygen and form anoxic environments conducive to the burial and preservation of ***,this study helps to further understand the organic-inorganic interactions caused by typical geological events and provides a guide for the next step of shale oil exploration and development in other lacustrine basins in China.

关键词： Volcanic ash Hydrocarbon generation Organic-rich shale Shahejie Formation Jiyang Depression

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