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Journal of Materials Science & Technology 2021年第6期65卷 61-71页

作者： ping deng Qunjia Peng En-Hou Han wei Ke Chen Sun CAS Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal ResearchChinese Academy of Sciences.Shenyang 110016China Nuclear Power Institute of China Chengdu 610213China Suzhou Nuclear Power Research Institute Suzhou 215004China State Power Investment Corporation Research Institute Beijing 102209China

Localized deformation and corrosion in irradiated 304 nuclear grade stainless steel in simulated primary water were *** investigation was conducted by comparing the deformation structure,the oxide scale formed at the deformation structure,and their correlation with *** results revealed that increasing the irradiation dose promoted localized corrosion at the slip step and grain boundary,which was primarily attributed to the strain concentration induced by enhanced localized deformation and depletion of Cr at grain ***,a synergic effect of the enhanced localized deformation and localized corrosion at the slip step and grain boundary caused a higher cracking susceptibility of the irradiated steel.

关键词： Stainless steel AFM TEM High temperature corrosion Stress corrosion

Metastable seed-crystals: epitaxial growth of branched-array organic heterostructure nanowires

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Science China Chemistry 2025年

作者： Jin Feng Zhen-Yu Geng Ting-Yao Song Ying-Xin Ma Chuan-Zeng Wang wei Zhang Hong-Tao Lin Jin Zhou Shu-ping Zhuo Shu-Hai Chen Xue-Dong Wang School of Chemistry and Chemical Engineering Shandong University of Technology Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials & DevicesSoochow University College of Chemistry and Chemical Engineering Hunan Normal University

Tunable light–matter interactions are exhibited by organic low-dimensional crystals, making these crystals a promising platform for organic photonics. However, the precise synthesis of organic low-dimensional crystals remains challenging due to the stochastic nature of molecular nucleation processes. Herein, the directed nucleation process is driven by the introduction of metastable seed-crystals as the trunk, which ultimately leads to branched-array organic heterostructures. The successful formation of organic heterostructures with high-density branched arrays is attributed to the highest attachment energy (Eatt（023）=-104.25 kcal mol-1) of the exposed （023） crystal plane during the seed-crystal growth route. Significantly, these as-prepared heterostructures inherently have an ultralow lattice mismatch ratio η of 0.7%between trunk and branch, which contributes to the multi-channel photon transportation. Therefore, this work provides valuable insights into a versatile synthetic strategy for accessing low-dimensional heterostructures for integrated optoelectronics.

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拉哇水电站泄水建筑物进水口边坡地震动力响应及稳定性分析

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地震工程与工程振动 2025年第1期45卷 132-142页

作者：邓旭刘东王庆祥位伟姜清辉武汉大学土木建筑工程学院湖北武汉430072 中国电建集团中南勘测设计研究院有限公司湖南长沙410014

我国西南地区水电工程边坡高陡且位于高地震烈度区域,存在地震诱发边坡失稳风险。以金沙江拉哇水电站泄水建筑物进水口边坡工程为依托,基于动力有限元方法对边坡罕遇强度地震工况进行模拟,在此基础上分析了边坡动力响应规律,研究了震后... 详细信息

我国西南地区水电工程边坡高陡且位于高地震烈度区域,存在地震诱发边坡失稳风险。以金沙江拉哇水电站泄水建筑物进水口边坡工程为依托,基于动力有限元方法对边坡罕遇强度地震工况进行模拟,在此基础上分析了边坡动力响应规律,研究了震后边坡变形、应力及塑性区分布情况,最后采用动力强度折减法评价了泄水建筑物以下边坡的动力稳定性,并揭示了其潜在失稳机制。结果表明:地震作用下边坡加速度响应呈现出高程放大效应、坡表放大效应和结构面放大效应等规律,边坡震后产生最大10.2 mm的永久变形,并新增局部拉应力区及塑性区,罕遇地震工况下边坡潜在滑体的安全系数为1.80,其潜在失稳机制是以断层JF1为后缘面剪切坡脚岩体发生变形破坏。研究可为含顺倾断层的复杂高陡岩质边坡在地震作用下的动力响应及稳定性分析提供参考。

关键词：高陡岩质边坡地震作用动力响应震后应力变形动力稳定性

Making stereopsis related to the ability of ocular deviation:a new paradigm for assessment of intermittent exotropia

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International Journal of Ophthalmology(English edition) 2025年第2期18卷 308-314页

作者： Jian-Bing Li Wan-Ting Kong Tao Shen Yong-Guang Yuan Chong-Lin Chen Dan-Min Peng Min-Tong Liang Xuan He Dan Luo Jia-Yi Su wei Wang Rui-Xin Wang Xin-ping Yu State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangzhou 510623Guangdong ProvinceChina Department of Ophthalmology the Third Affiliated HospitalSun Yat-Sen UniversityGuangzhou 510630Guangdong ProvinceChina Guangzhou Xinhua University Guangzhou 510520Guangdong ProvinceChina

AIM:To investigate the underlying factors by establishing a new paradigm for assessing control ability under stereopsis testing ***:This was a prospective observational *** evaluated the control ability of intermittent exotropia(IXT)patients in three conditions:natural 2D optotype viewing,2D optotype viewing with polarized glasses,and 3D optotype viewing with polarized *** with a smartphone,we captured videos to analyze the accurate time of spontaneous exodeviation and subsequent realignment before and after breaking ***,the correlation of stereopsis were also ***:A total of 48 patients(age range:4-33y;54.17%male)participated in the *** viewing 3D optotypes with polarized glasses,their median control scores were 1(interquartile range,0-4)at distance and 0(0-1)at *** scores were significantly better than those observed under natural viewing conditions,which were 2.5(1-5)at a distance and 1(0-3)at near(Friedman test,P=0.049).Furthermore,those subjects who exhibited exophoria(realignment within 2 seconds)while viewing 3D optotypes with polarized glasses were more likely to have measurable stereo vision(Kendall’sτb=-0.344,P=0.018).CONCLUSION:IXT patients exhibit enhanced control ability when using polarized glasses to view 3D optotypes,notably improving realignment *** expands our understanding of current tests and offers a potentially sensitive method for assessing IXT severity.

关键词： intermittent exotropia stereopsis control ability

马克思批判性研究思路中的问题意识及其思考的系统性

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广西师范大学学报（哲学社会科学版） 2025年第1期61卷 1-10页

作者：魏小萍新疆大学马克思主义学院新疆乌鲁木齐830046 中国社会科学院大学哲学系北京102488

马克思批判性研究思路从早期的法学、哲学、道德视域的思考深入到现实社会经济关系领域,并转向政治经济学批判性研究,与此相应,马克思关注的问题意识也随着研究思路的进程发生着相应变化。这些问题意识彼此之间并非互不相干,它们围绕着... 详细信息

马克思批判性研究思路从早期的法学、哲学、道德视域的思考深入到现实社会经济关系领域,并转向政治经济学批判性研究,与此相应,马克思关注的问题意识也随着研究思路的进程发生着相应变化。这些问题意识彼此之间并非互不相干,它们围绕着马克思的核心研究思路,即人类解放理念而展开。这一理念由早期抽象的自由和平等发展到在新历史观视域下以生产手段社会占有为基础的全面自由和以超越回馈正义原则为基础的现实平等。贯穿于马克思哲学思考与政治经济学批判性研究之间的是政治哲学思考。以这一脉络为线索,我们能在马克思不同时期、不同领域研究思路的问题域中看到其研究思路的内在连续性与系统性。

关键词：马克思劳动所得双重对象性关系批判思路

Lens coloboma with bilateral ectopia lentis in Marfan syndrome:a case report

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International Journal of Ophthalmology(English edition) 2025年第2期18卷 358-361页

作者： Zhen-Bo Zhao Kai-Li Tang Yu-Xi Ding Ji-Kun Yang Huan-ping Wang Li-wei Ma Aier Eye Medical Center of Anhui Medical University Hefei 230031Anhui ProvinceChina Aier Excellence Eye Hospital Shenyang 110000Liaoning ProvinceChina

Dear Editor,We report a rare case of lens coloboma and several notches with bilateral ectopia lentis in Marfan *** case was approved by the Ethics Committee of Aier Excellence Eye Hospital(2023KJB0004).Written informed consent was obtained from the *** coloboma and Marfan syndrome are of low incidence and seldom observed in the clinic.

关键词： Marfan bilateral rare

The Optimal Investment,Liability and Dividends in Insurance

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Journal of the Operations Research Society of China 2021年第2期9卷 395-409页

作者： ping-Jin deng Xiu-Fang Li Xiao-wei Chen School of Finance Collaborative Innovation Center for China EconomyNankai UniversityTianjin 300071China

In this paper,we build an optimal control model with the objective to maximize the expected value of the time discount utility by selecting optimal investment,liability and dividend strategies for insurance *** then use the techniques from Merton(J Econ Theory 3(4):373–413,1971)to solve our optimal control problem and deduce the optimal control ***,we analyze the economic impacts on the optimal controls of the parameters in insurance market.

关键词： Asset and liability management Optimal dividends HJB equation

基于Z值回归模型诊断儿童冠状动脉病变的研究

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中国当代儿科杂志 2025年第2期27卷 176-183页

作者：王永蒋佳颖邓燕李波帅平胡小平张银滟吴寒叶露薇彭茜四川省医学科学院·四川省人民医院儿科四川成都610072 成都中医药大学四川成都610075 四川省医学科学院·四川省人民医院超声心脏电生理与生物力学四川省重点实验室四川成都610072 四川省医学科学院·四川省人民医院健康管理中心四川成都610072

目的构建四川地区儿童超声心动图冠状动脉内径Z值回归模型,建立Z值计算公式。方法选取2020年1月—2022年12月在四川省人民医院体检的744例健康儿童为建模组,选取2018年1月—2022年12月在该院诊断为川崎病的251例患儿为验证组,运用Pearso... 详细信息

目的构建四川地区儿童超声心动图冠状动脉内径Z值回归模型,建立Z值计算公式。方法选取2020年1月—2022年12月在四川省人民医院体检的744例健康儿童为建模组,选取2018年1月—2022年12月在该院诊断为川崎病的251例患儿为验证组,运用Pearson相关分析对冠状动脉内径值与年龄、身高、体重、体表面积进行分析,通过函数转换构建回归模型,找出最佳回归模型并建立Z值计算公式,并对模型进行验证。结果Pearson相关分析显示,左冠状动脉主干、左前降支、左回旋支、右冠状动脉内径值与体表面积相关系数分别为0.815、0.793、0.704、0.802(P<0.05)。在构建回归模型时,幂函数回归模型表现出最佳效果,因此选用幂函数模型作为建立Z值计算公式的最佳模型。基于此Z值计算公式,发现冠状动脉病变的检出率为21.5%(54/251),这一比例高于基于冠状动脉内径绝对值标准的检出率。特别是在左前降支和左回旋支中,使用该Z值计算公式获得的冠状动脉病变检出率高于既往的经典Z值计算公式。结论基于幂函数回归模型建立的Z值计算公式,冠状动脉病变的检出率较高,可为临床医生,特别是针对川崎病患儿冠状动脉病变的评估提供有力的参考依据。

关键词：川崎病冠状动脉病变冠状动脉 Z值超声心动图儿童

The role of ubiquitination in tumorigenesis and targeted drug discovery

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Signal Transduction and Targeted Therapy 2020年第1期5卷 2294-2321页

作者： Lu deng Tong Meng Lei Chen Wenyi wei ping Wang College of Animal Science and Technology Northwest A&F UniversityYangling Shaanxi 712100China Division of Spine Department of OrthopedicsTongji Hospital Affiliated to Tongji University School of Medicine389 Xincun RoadShanghaiChina Division of Laboratory Safety and Services Northwest A&F UniversityYangling Shaanxi 712100China Department of Pathology Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMA 02215USA Tongji University Cancer Center Shanghai Tenth People’s Hospital of Tongji UniversitySchool of MedicineTongji UniversityShanghai 200092China

Ubiquitination,an important type of protein posttranslational modification(PTM),plays a crucial role in controlling substrate degradation and subsequently mediates the“quantity”and“quality”of various proteins,serving to ensure cell homeostasis and guarantee life *** regulation of ubiquitination is multifaceted and works not only at the transcriptional and posttranslational levels(phosphorylation,acetylation,methylation,etc.)but also at the protein level(activators or repressors).When regulatory mechanisms are aberrant,the altered biological processes may subsequently induce serious human diseases,especially various types of *** tumorigenesis,the altered biological processes involve tumor metabolism,the immunological tumor microenvironment(TME),cancer stem cell(CSC)stemness and so *** regard to tumor metabolism,the ubiquitination of some key proteins such as RagA,mTOR,PTEN,AKT,c-Myc and P53 significantly regulates the activity of the mTORC1,AMPK and PTEN-AKT signaling *** addition,ubiquitination in the TLR,RLR and STING-dependent signaling pathways also modulates the ***,the ubiquitination of core stem cell regulator triplets(Nanog,Oct4 and Sox2)and members of the Wnt and Hippo-YAP signaling pathways participates in the maintenance of CSC *** on the altered components,including the proteasome,E3 ligases,E1,E2 and deubiquitinases(DUBs),many molecular targeted drugs have been developed to combat *** them,small molecule inhibitors targeting the proteasome,such as bortezomib,carfilzomib,oprozomib and ixazomib,have achieved tangible *** addition,MLN7243 and MLN4924(targeting the E1 enzyme),Leucettamol A and CC0651(targeting the E2 enzyme),nutlin and MI‐219(targeting the E3 enzyme),and compounds G5 and F6(targeting DUB activity)have also shown potential in preclinical cancer *** this review,we summarize the latest progress in understanding the substrates for ubiquitination and their special functions

关键词： metabolism ubiquitin targeted

利用CSST/MCI鉴别系外行星透射谱的恒星污染

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天文学报 2025年第1期66卷 80-93页

作者：邓莹平蒋承孜陈果颜召军中国科学院紫金山天文台南京210023 中国科学技术大学天文与空间科学学院合肥230026 中国科学院行星科学重点实验室南京210023 中国科学院上海天文台上海200030

中国巡天空间望远镜(Chinese Survey Space Telescope,CSST)预计对系外行星开展大气观测研究,这为系外行星观测领域提供了新的机遇.目前主要通过凌星透射谱来研究系外行星大气.然而,实际观测数据中已经发现恒星活动存在的迹象,且结果表... 详细信息

中国巡天空间望远镜(Chinese Survey Space Telescope,CSST)预计对系外行星开展大气观测研究,这为系外行星观测领域提供了新的机遇.目前主要通过凌星透射谱来研究系外行星大气.然而,实际观测数据中已经发现恒星活动存在的迹象,且结果表明难以准确约束恒星活动污染.所以,如何准确区分并剔除恒星活动污染是透射光谱学的一个重大挑战.因此,在选择透射谱观测目标进行跟进观测时,需要对潜在的恒星污染及其可区分性进行定量评估,这需要大规模的仿真来提供预期数据.利用多色测光法结合机器学习来判别系外气态行星大气透射谱中是否存在潜在的恒星污染,针对CSST的多通道相机(Multi-Channel Imager,MCI)设计能准确预判透射谱是否存在恒星污染的滤光片观测组合,可为后续系外行星大气观测目标的策略制定提供一定的参考.

关键词：方法:统计方法:数据分析技术:测光恒星:活动恒星:星斑行星和卫星:大气

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