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普光净化厂尾气酸水汽提工艺优化研究及应用

化学工程 2015年第10期43卷 73-78页

作者：魏荆辉张恒伟李庆男康健李伟松许春建中国石化中原油田普光天然气净化厂四川达州636150 天津大学化工学院化学工程联合国家重点实验室天津300072 天津化学化工协同创新中心天津300072

针对普光天然气净化厂酸水汽提净化水质合格率偏低的问题,采用了工艺模拟和实验的方法对净化厂的酸水单塔低压汽提工艺进行了研究。利用过程模拟软件Pro/Ⅱ以及现场实际生产数据建模并对酸水汽提工艺进行了模拟优化,工艺模拟优化结果表... 详细信息

针对普光天然气净化厂酸水汽提净化水质合格率偏低的问题,采用了工艺模拟和实验的方法对净化厂的酸水单塔低压汽提工艺进行了研究。利用过程模拟软件Pro/Ⅱ以及现场实际生产数据建模并对酸水汽提工艺进行了模拟优化,工艺模拟优化结果表明进料温度为影响汽提效果关键因素。根据操作参数和改进的工艺流程模拟优化结果,设计了一套汽提中试装置并开展了现场实验,实验结果验证了进料温度为影响汽提效果的关键因素这一结论,同时根据实验结果确定了酸水汽提的最优工艺条件为进料温度74℃,且塔顶汽提采出量为10%。根据汽提工艺优化结果对一联合车间酸水汽提塔进行了工艺改造,改造可显著改善净化水质,使得净化水中硫化物和氨氮质量浓度分别控制在0.1 mg/L和10 mg/L以下。

关键词：酸水汽提工艺优化技术改造

Dissecting the cell microenvironment of ovarian endometrioma through single-cell RNA sequencing

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Science China life Sciences 2025年第1期68卷 116-129页

作者： Jiangpeng Wu Siyu Xia Wenting Ye Yan Sun Jing Cai Fubing Yu Haiping Wen Xiuwei Yi Taikang li Mingwei Chen Jiayun Chen Ge song Chuanbin Yang Yali song Jigang Wang Department of Reproductive Medicine Dongguan Maternal and Child Health Care Hospital Department of Urology and Shenzhen Clinical Research Centre for GeriatricsShenzhen People's HospitalSouthern University of Science and Technology State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs Artemisinin Research Centerand Institute of Chinese Materia MedicaChina Academy of Chinese Medical Sciences Reproductive Medicine Center Foshan Women and Children Hospital State Key Laboratory of Antiviral Drugs School of PharmacyHenan University

Ovarian endometrioma（OE）, also known as “chocolate cysts,” is a cystic mass that develops in the ovaries due to endometriosis and is a common gynecological condition characterized by the growth of endometrial tissue outside the uterus, leading to symptoms such as dysmenorrhea, pelvic pain, and infertility. However, the precise molecular and cellular mechanisms driving this pathophysiology remain largely unknown, posing challenges for diagnosis and treatment. Here, we employed integrated single-cell transcriptomic profiling of over 52,000 individual cells from endometrial tissues of OE patients and healthy donors and identified twelve major cell populations. We identified notable alterations in cell type-specific proportions and molecular signatures associated with OE. Notably, the activation of IGFBP5+macrophages with pro-inflammatory properties, NK cell exhaustion, and aberrant proliferation of IQCG+and KLF2+epithelium are key features and may be the potential mechanisms underlying the pathogenesis of OE. Collectively, our data contribute to a better understanding of OE at the single cell level and may pave the way for the development of novel therapeutic strategies.

关键词： ovary high-throughput sequencing transcriptomics gene expression analysis ligand-receptor analysis

Tectonic modes of mantle convection and their implications for Earth's tectonic evolution based on three-dimensional numerical simulations

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Science China Earth Sciences 2025年第1期68卷 270-296页

作者： song XIANG Jinshui HUANG Bingcheng WU School of Earth and Space Sciences University of Science and Technology of China CAS Center of Excellence in Comparative Planetary Studies

Five tectonic modes of mantle convection are obtained and analyzed with three-dimensional numerical models in a spherical shell domain. The five tectonic convective modes are non-plate mobile-lid, plate-like mobile-lid, episodic plate-like mobile-lid, episodic stagnant-lid, and stagnant-lid convective modes, respectively. The typical characteristics of these five tectonic modes and their numerical classification criteria based on plateness, mobility, and their standard deviations are presented and discussed. The results show that the yield stress of the lithosphere has profound effects on the tectonic convective *** the gradual increase of yield stress, the tectonic mode of mantle convection changes from one to another sequentially through the aforementioned five modes. Additionally, as the Rayleigh number increases, the range of yield stress for the platelike mobile-lid convective mode decreases, and the dimensionless transition stress between different tectonic modes ***, the dimensional transition stress between the non-plate mobile-lid convective mode and plate-like mobile-lid convective mode increases with the increase of Rayleigh number, but decreases between other tectonic modes. Furthermore, we find that the transition stress between different tectonic modes is inversely proportional to the internal heating rate, with the transition stress decreasing as the internal heating rate increases. The fitting analysis of the transition stress between tectonic modes shows that Earth's current plate tectonics correspond to a lithospheric yield stress of 150–250 MPa, which aligns with the strength of serpentinized mantle rock determined by experimental petrography. If the Archean mantle was 300°C warmer than it is today, then the Earth was in an episodic stagnant-lid convective mode. The tectonic evolution of the Earth's surface is closely related to the lithospheric strength and the process of thermal evolution. If the lithospheric strength w

关键词： Tectonic mode of mantle convection Plate-like mobile-lid convection Episodic plate-like mobile-lid convection Episodic stagnant-lid convection Plate tectonics and tectonic evolution of the Earth

Repetitive traumatic brain injury–induced complement C1–related inflammation impairs long-term hippocampal neurogenesis

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Neural Regeneration Research 2025年第3期20卷 821-835页

作者： Jing Wang Bing Zhang Lanfang li Xiaomei Tang Jinyu Zeng Yige song Chao Xu Kai Zhao Guoqiang liu Youming Lu Xinyan li Kai Shu Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Neurosurgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Pathophysiology School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Institute for Brain Research Wuhan Center of Brain ScienceHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Graduate Student Chongqing Medical UniversityChongqingChina Department of Basic Medicine School of Medical ScienceHubei University for NationalitiesEnshiHubei ProvinceChina Department of Anatomy School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Repetitive traumatic brain injury impacts adult neurogenesis in the hippocampal dentate gyrus,leading to long-term cognitive ***,the mechanism underlying this neurogenesis impairment remains *** this study,we established a male mouse model of repetitive traumatic brain injury and performed long-term evaluation of neurogenesis of the hippocampal dentate gyrus after repetitive traumatic brain *** results showed that repetitive traumatic brain injury inhibited neural stem cell proliferation and development,delayed neuronal maturation,and reduced the complexity of neuronal dendrites and *** with repetitive traumatic brain injuryalso showed deficits in spatial memory ***,following repetitive traumatic brain injury,neuroinflammation was enhanced in the neurogenesis microenvironment where C1q levels were increased,C1q binding protein levels were decreased,and canonical Wnt/β-catenin signaling was *** inhibitor of C1 reversed the long-term impairment of neurogenesis induced by repetitive traumatic brain injury and improved neurological *** findings suggest that repetitive traumatic brain injury–induced C1-related inflammation impairs long-term neurogenesis in the dentate gyrus and contributes to spatial memory retrieval dysfunction.

关键词： complement C1 dendrite dentate gyrus hippocampus neural stem cell neurogenesis neuroinflammation neurological function neuron traumatic brain injury

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基于小波变换阈值去噪算法的改进

计算机仿真 2021年第6期38卷 348-351,356页

作者：李维松许伟杰张涛中国科学院声学研究所东海研究站上海201815 中国科学院大学北京100089

小波变换在信号的滤波降噪处理中应用非常广泛,针对传统小波阈值去噪算法中软、硬阈值函数以及Garrote阈值函数的不足,构造出一个新的阈值函数,并采用新的阈值确定方法,对信号的去噪处理更加灵活,克服了传统阈值函数的不足。通过Matlab... 详细信息

小波变换在信号的滤波降噪处理中应用非常广泛,针对传统小波阈值去噪算法中软、硬阈值函数以及Garrote阈值函数的不足,构造出一个新的阈值函数,并采用新的阈值确定方法,对信号的去噪处理更加灵活,克服了传统阈值函数的不足。通过Matlab软件,对传统阈值函数以及本文提出的改进阈值函数进行去噪处理仿真,在信噪比(SNR)和均方误差(MSE)两个方面进行定量对比。实验结果表明,使用改进的阈值函数进行去噪处理后,信号具有更高的信噪比和更小的均方误差,去噪效果优于传统方法。

关键词：小波阈值去噪阈值阈值函数均方误差信噪比

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不同沉降方式下大型储罐的变形与应力分析

空间结构 2016年第4期22卷 78-84页

作者：黎伟宋伟宋金丽雷鸿翔袁圣桐杨牧周妍竹西南石油大学机电工程学院四川成都610500 石油天然气装备教育部重点实验室四川成都610500

大型石油储罐是一种短柱圆形薄壁壳体结构,对地基沉降十分敏感,其中地基局部不均匀沉降和地基整体倾斜对罐体的影响最为关键.采用有限元方法,研究分析了在地基整体倾斜1.5°和地基局部不均匀沉降达到20mm的情况下,大型石油储罐的变形形... 详细信息

大型石油储罐是一种短柱圆形薄壁壳体结构,对地基沉降十分敏感,其中地基局部不均匀沉降和地基整体倾斜对罐体的影响最为关键.采用有限元方法,研究分析了在地基整体倾斜1.5°和地基局部不均匀沉降达到20mm的情况下,大型石油储罐的变形形态以及应力分布特征.结果表明,地基整体倾斜沉降最大变形发生在储罐中下部,最大Mises应力发生在罐壁下部;局部不均匀沉降最大变形发生在敞口顶部,变形形态表现为褶皱式扭曲凹凸,并且具有简谐波形的特性;罐壁内最大Mises应力位于局部沉降区域内的罐壁和底板焊接处.结果同时也表明,地基整体倾斜沉降和局部不均匀沉降都会造成储罐较大的径向变形而导致浮盘升降困难,减小储罐的容量;罐周局部不均匀沉降还会造成罐壁与底板的焊缝撕裂,导致储液泄漏.

关键词：大型储罐整体倾斜沉降局部不均匀沉降储罐变形储罐应力

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先天性食管闭锁外科治疗概况

临床外科杂志 2011年第8期19卷 515-517页

作者：李巍松安徽医科大学第一附属医院小儿外科 230022

先天性食管闭锁（oesophageal atresia，OA）是一组少见而威胁生命的食管先天畸形的总称，包括食管闭锁合并或者不合并气管食管瘘，以及单纯的食管气管瘘。流行病学研究表明，其发病率大约为3000～5000活产婴儿中有1例”，发病无性别倾... 详细信息

先天性食管闭锁（oesophageal atresia，OA）是一组少见而威胁生命的食管先天畸形的总称，包括食管闭锁合并或者不合并气管食管瘘，以及单纯的食管气管瘘。流行病学研究表明，其发病率大约为3000～5000活产婴儿中有1例”，发病无性别倾向，目前大多学者认为其为散发性疾病，家族性食管闭锁非常罕见，病例不足1％，但在双胞胎其发生率会上升2～3倍。

关键词：先天性食管闭锁诊断病理分型治疗

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儿童不典型的进展期阑尾炎临床研究

中华小儿外科杂志 2006年第2期27卷 75-77页

作者：李巍松施诚仁余世耀上海交通大学附属新华医院小儿外科 200092

目的探讨儿童不典型进展期阑尾炎的临床特点。方法回顾性的调查2002年1月-2004年8月415例进展期阑尾炎，根据改良Alvarado评分把患儿分成不典型组、疑似组、典型组三组，比较各组之间的临床特点，总结不典型的进展期阑尾炎的临床特点。... 详细信息

目的探讨儿童不典型进展期阑尾炎的临床特点。方法回顾性的调查2002年1月-2004年8月415例进展期阑尾炎，根据改良Alvarado评分把患儿分成不典型组、疑似组、典型组三组，比较各组之间的临床特点，总结不典型的进展期阑尾炎的临床特点。结果不典型组与典型组患儿之间在年龄分布、肥胖的有无、阑尾位置分布之间有一定的差异性。不典型组4岁以下儿童比例相对较高；肥胖的患儿比例相对较高；它们在阑尾位置分布上是有差别的，典型组以回肠前和盆位为主，而不典型组以盲肠后以及回肠后为主。结论儿童进展期阑尾炎的不典型表现与患儿的低龄、肥胖及阑尾位置有关，单纯使用建立在临床症状基础上的评分系统，可能会延误这些患儿的治疗。

关键词：儿童阑尾炎

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甘蔗蜡提取物对对比剂肾病大鼠的保护作用

湖北农业科学 2013年第3期52卷 610-612,617页

作者：廖芳李伟松陈伟伟钟琳玲赣南医学院药学院药理学教研室江西赣州341000 赣南医学院药学院病理学教研室江西赣州341000 赣州市人民医院心内科江西赣州341000

为了研究甘蔗蜡提取物多廿烷醇(Policosanol)对对比剂肾病(Contrast-induced nephrpathy,CIN)大鼠的保护作用,将32只Wistar大鼠随机分为4组,每组8只,分别为正常对照组(C),甘蔗蜡提取物多廿烷醇组(P)、对比剂组(Contrast media,CM)和甘... 详细信息

为了研究甘蔗蜡提取物多廿烷醇(Policosanol)对对比剂肾病(Contrast-induced nephrpathy,CIN)大鼠的保护作用,将32只Wistar大鼠随机分为4组,每组8只,分别为正常对照组(C),甘蔗蜡提取物多廿烷醇组(P)、对比剂组(Contrast media,CM)和甘蔗蜡提取物多廿烷醇+对比剂组(PCM)。通过尾静脉分别注射吲哚美辛(10 mg/kg)、N-硝基-L-精氨酸甲酯(L-NAME,10 mg/kg,15、30 min各注射1次)、高渗性对比剂60%泛影葡胺(6 mL/kg)诱导对比剂肾病。测定肾功能参数,进行肾组织形态学检查。结果表明,与CM组相比,PCM组大鼠血清肌酐显著下降(P<0.05),内生肌酐清除率显著上升(P<0.05),大鼠肾切片肾小管坏死和髓质充血都显著减少(P<0.05)。说明甘蔗蜡提取物多廿烷醇能阻止对比剂肾病的进程。

关键词：多廿烷醇(Policosanol) 对比剂肾病(Contrast-induced nephrpathy,CIN) 大鼠保护作用