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L^(p) Decay Rate for a Nonlinear Convection Diffusion Reaction Equation in R~n

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Acta Mathematicae Applicatae Sinica 2021年第2期37卷 380-392页

作者： guo-wei liu Hong-mei XU Yuan-mei XIA School of Mathematical Sciences Chongqing Normal UniversityChongqing 40000China Faculty of Science Hohai UniversityNanjing 211100China

This paper studies the asymptotic behavior of solutions for a nonlinear convection diffusion reaction equation in R^(n).Firstly,the global existence and uniqueness of classical solutions for small initial data are ***,we obtain the L^(p),2≤p≤+∞decay rate of *** approach is based on detailed analysis of the Green function of the linearized equation with the technique of long wave-short wave decomposition and the Fourier analysis.

关键词： convection diffusion reaction equation Green function L^(p)decay rate

Privacy-Preserving Consensus-Based Distributed Economic Dispatch of Smart Grids via State Decomposition

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IEEE/CAA Journal of Automatica Sinica 2024年第5期11卷 1250-1261页

作者： wei Chen guo-Ping liu The authors are with the Center for Control Science and Technology Southern University of Science and TechnologyShenzhen 518055China

This paper studies the privacy-preserving distributed economic dispatch(DED)problem of smart *** autonomous consensus-based algorithm is developed via local data exchange with neighboring nodes,which covers both the islanded mode and the grid-connected mode of smart *** prevent power-sensitive information from being disclosed,a privacy-preserving mechanism is integrated into the proposed DED algorithm by randomly decomposing the state into two parts,where only partial data is *** objective is to develop a privacy-preserving DED algorithm to achieve optimal power dispatch with the lowest generation cost under physical constraints while preventing sensitive information from being *** this end,a comprehensive analysis framework is established to ensure that the proposed algorithm can converge to the optimal solution of the concerned optimization problem by means of the consensus theory and the eigenvalue perturbation *** particular,the proposed autonomous algorithm can achieve a smooth transition between the islanded mode and the grid-connected ***,rigorous analysis is given to show privacy-preserving performance against internal and external ***,case studies illustrate the feasibility and validity of the developed algorithm.

关键词： preserving autonomous mode

Inhibitory Effect of Progesterone on Inflammatory Factors After Experimental Traumatic Brain Injury

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Biomedical and Environmental Sciences 2007年第5期20卷 432-438页

作者： DE-SHENG PAN wei-guo liu XIAO-FENG YANG AND FEI CAO Department of Neurosurgery The First Affiliated Hospital Medical College of Zhejiang University Hangzhou 310003 Zhejiang China Department of Neurosurgery The Second Affiliated Hospital Medical College of Zhejiang University Hangzhou 310009 Zhejiang China

Objective Traumatic brain injury （TBI） is one of the leading causes of morbidity and mortality in young people. Inflammatory cytokines play an important part in the pathophysiology of TBI. Recent studies demonstrate that progesterone significantly reduces cerebral edema and enhances functional recovery from TBI and stroke in several animal models. This study was designed to investigate the inhibitory effect of progesterone on inflammatory response after traumatic brain injury. Methods Progesterone was injected intraperitoneally using rats as a model of traumatic brain injury, and Western blot technique was applied to detect the expression of three inflammation-related factors： nuclear factor kappa B p65 （NFκB p65）, glial fibrillary acidic protein （GFAP）, and tumor necrosis factor-α （TNF-α）. The water content of injured brain was also examined. A neurological severity score was recorded to evaluate the effect of progesterone on neurodeficit recovery. Results NFκB p65, GFAP, and TNF-α were increased in all injured animals. In rats treated with progesterone, the expression level of NFκB p65 and TNF-α were reduced significantly in comparison with vehicle-treated rats. However, progesterone did not alter the expression of GFAP in the injured rats. Progesterone also reduced the water content of injured brain and the lesion volume. In addition, progesterone-treated injured rats showed significant improvements in the Neurological Severity Score test, compared with vehicle-treated ones. Conclusions Progesterone inhibits the inflammatory response after experimental traumatic brain injury and mitigates the severity of brain damage.

关键词： Traumatic brain injury Progesterone Inflammation

Disturbance Observer-Based Predictive Tracking Control of Uncertain HOFA Cyber-Physical Systems

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IEEE/CAA Journal of Automatica Sinica 2024年第7期11卷 1711-1713页

作者： Da-wei Zhang guo-Ping liu IEEE the Center for Control Theory and Guidance Technology Harbin Institute of TechnologyHarbin 150001China the Center for Control Science and Technology Southern University of Science and TechnologyShenzhen 518055China

Dear Editor,In this letter,an output tracking control problem of uncertain cyber-physical systems(CPSs)is considered in the perspective of high-order fully actuated(HOFA)system theory,where a lumped disturbance is use... 详细信息

关键词： Observer Uncertain letter

Experimental Study on Combustion Characteristics of Pulverized Coal under Enriched-oxygen Condition by Entrained Flow Reactor

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Journal of Harbin Institute of Technology(New Series) 2013年第1期20卷 46-51页

作者： guo-wei liu Dao-Zhi Qu Peng Dong Ru-Shan Bie School of Energy Science and Engineering Harbin Institute of Technology

Four different pulverized coals have been used to study the effects of oxygen concentration on combustion characteristics under different enriched-oxygen conditions by entrained flow reactor experiments. The results show that: with the increase of oxygen concentration, the ignition temperature of four coals greatly decreases and the low volatile coals decrease faster; with the increase of oxygen concentration, the ignition mode of pulverized coal has an obviously transformation from homogeneous ignition to heterogeneous ignition, and the corresponding oxygen concentrations are about 40% and 50%-60% respectively for bituminous coal and lignite, and both about 30% for lean coal and anthracite; with the increase of oxygen concentration, the optimal pulverized coal concentrations of bituminous coal and lignite increase firstly and then decrease, but for lean coal and anthracite, the optimal pulverized coal concentrations decrease slowly with the increase of oxygen concentration.

关键词： enriched-oxygen condition combustion characteristics entrained flow reactor ignition mode

Preparation and Swelling Kinetic Analysis of Poly (HPMC-co-AA-co-AM) Super Absorbent Resin

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Journal of Wuhan University of Technology(Materials Science) 2024年第3期39卷 790-799页

作者：马砺 WANG Xin liu Xixi wei Gaoming guo Ying School of Safety Science and Engineering Xi’an University of Science and TechnologyXi'an 710054China Key Laboratory of Coal Fire Disaster Prevention Xi’an University of Science and TechnologyXi'an 710054China School of Energy Engineering Xi’an Uni-versity of Science and TechnologyXi'an 710054China Yanzhou Coal Mining Co. Ltd.Zoucheng 237500China

Super absorbent resin(SAR)is prepared by aqueous high temperature polymerization using hydroxypropyl methylcellulose(HPMC)as monomer backbone material,acrylic acid(AA)and acrylamide(AM)as the graft copolymer monomer,potassium persulfate(KPS)as the initiator to generate free radicals,and N,N`-methylenebisacrylamide(MBA)as cross-linking agent for cross-linking ***,the influence of individual factors on the water absorption is investigated,and these factors are mainly AA,AM,KPS,MBA,HPMC,and reaction *** optimized conditions are obtained by the experiment repeating for several *** water absorption multiplicity and salt absorption multiplicity under the conditions are 782.4 and 132.5 g/g,***,the effects of different temperatures and salt concentrations on its water absorption,as well as the swelling kinetics of SAR are *** is indicated the water-absorbing swelling process is mainly caused by the difference in water osmotic pressure and Na+concentration inside and outside the cross-linked molecular structure of the resin,which is not only consistent with the quasi-secondary kinetic model,but also with the Fick diffusion model.

关键词： super absorbent resin swelling kinetics water absorption graft copolymerization hydroxypropyl methyl cellulose

Engineering vascularized organotypic tissues via module assembly

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International Journal of Extreme Manufacturing 2024年第1期6卷 155-175页

作者： Zhenzhen Zhou Changru liu Yuting guo Yuan Pang wei Sun Biomanufacturing Center Department of Mechanical EngineeringTsinghua UniversityHaidian DistrictBeijing 100084People’s Republic of China Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing Beijing 100084People’s Republic of China Key Laboratory for Advanced Materials Processing Technology Ministry of EducationBeijing 100084People’s Republic of China Department of Mechanical Engineering Drexel UniversityPhiladelphiaPA 19104United States of America

Adequate vascularization is a critical determinant for the successful construction and clinical implementation of complex organotypic tissue models. Currently, low cell and vessel density and insufficient vascular maturation make vascularized organotypic tissue construction difficult,greatly limiting its use in tissue engineering and regenerative medicine. To address these limitations, recent studies have adopted pre-vascularized microtissue assembly for the rapid generation of functional tissue analogs with dense vascular networks and high cell density. In this article, we summarize the development of module assembly-based vascularized organotypic tissue construction and its application in tissue repair and regeneration, organ-scale tissue biomanufacturing, as well as advanced tissue modeling.

关键词： vascularized organotypic tissue module assembly regenerative medicine tissue engineering

The pathogenesis of Parkinson’s disease and crosstalk with other diseases

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BIOCELL 2024年第8期48卷 1155-1179页

作者： TINGTING liu DINGYOU guo JIANSHE wei Institute for Brain Sciences Research School of Life SciencesHenan UniversityKaifeng475004China

In China,Parkinson’s disease(PD)is the second most prevalent central nervous system(CNS)degenerative illness affecting middle-aged and older *** disorders including resting tremor,bradykinesia,myotonia,postural instability,and gait instability are the predominant clinical *** two main types of PD are sporadic and familial,with sporadic PD being the more prevalent of the *** environment,genetics,mitochondrial dysfunction,oxidative stress,inflammation,protein aggregation and misfolding,loss of trophic factors,cell death,and gut microbiota may all have a role in the etiology of *** is inversely connected with other cancers and positively correlated with COVID-19,diabetes mellitus(DM),melanoma,and ischemic heart disease(IHD)*** disease progression,managing motor and non-motor symptoms,and avoiding and controlling dysfunction in the middle and later phases of the disease are the key areas of research and development for its ***,the development and progression of PD can be slowed down by using conventional pharmacology,natural items,and innovative *** article reviews the pathogenesis of PD,its correlations with other non-genetic diseases,and the research progress of drugs and technologies for alleviating PD.

关键词： Parkinson’s disease Mitochondrial dysfunction Oxidative stress Inflammation Cancer Therapies

Agomelatine:a potential novel approach for the treatment of memory disorder in neurodegenerative disease

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Neural Regeneration Research 2023年第4期18卷 727-733页

作者： Qiang Su Tian Li guo-wei liu Yan-Li Zhang Jun-Hong guo Zhao-Jun Wang Mei-Na Wu Jin-Shun Qi Key Laboratory of Cellular Physiology Ministry of EducationShanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Physiology Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Neurology First Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Laboratory Medicine Fenyang College of Shanxi Medical UniversityFenyangShanxi ProvinceChina Department of Neurology Sixth Hospital of Shanxi Medical University(General Hospital of Tisco)TaiyuanShanxi ProvinceChina

Agomelatine is a selective agonist of melatonin receptor 1A/melatonin receptor 1B(MT/MT)and antagonist of 5-hydroxytryptamine 2C *** is used clinically to treat major depressive episodes in *** pro-chronobiological activity of agomelatine reconstructs sleep-wake rhythms and normalizes circadian disturbances via its agonistic effect of melatonin receptor 1A/melatonin receptor 1B,which work simultaneously to counteract depression and anxiety ***,by antagonizing neocortical postsynaptic 5-hydroxytryptamine 2C receptors,agomelatine enhances the release of dopamine and noradrenaline in the prefrontal cortex,increases the activity of dopamine and noradrenaline,and thereby reduces depression and anxiety *** combination of these two effects means that agomelatine exhibits a unique pharmacological role in the treatment of depression,anxiety,and disturbance of the circadian *** and sleep are closely related to memory and cognitive *** disorder is defined as any forms of memory abnormality,which is typically evident in a broad range of neurodegenerative diseases,including Alzheimer’s *** impairment and cognitive impairment are common symptoms of neurodegenerative and psychiatric ***,whether agomelatine can improve memory and cognitive behaviors if used for alleviating depression and circadian-rhythm sleep disorders has become a research“hotspot”.This review presents the latest findings on the effects of agomelatine in the treatment of psychologic and circadian-rhythm sleep disorders in clinical trials and animal *** review evaluates recent studies on treatment of memory impairment and cognitive impairment in neurodegenerative and psychiatric diseases.

关键词： agomelatine antidepressant anxiety apathy circadian-rhythm sleep disorder cognitive impairment depression melatonergic memory disorder mood disorder neurodegenerative disease