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Global pattern and trend of liver cancer survival: a systematic review of population-based studies

Hepatoma Research 2020年第8期6卷 78-90页

作者： Yu-Fei Jiang Zhuo-ying Li Xiao-wei Ji Qiu-Ming Shen Jia-Yi Tuo Hui-Yun Yuan Yong-Bing Xiang School of Public Health Shanghai Jiaotong University School of MedicineShanghai 200025China State Key Laboratory of Oncogene and Related Genes&Department of Epidemiology Shanghai Cancer InstituteRenji HospitalShanghai Jiaotong University School of MedicineShanghai 200032China Renji Hospital Shanghai Jiaotong University School of MedicineShanghai 200032China

Aim:To describe the global pattern and trend of liver cancer survival,using data from the population-based studies or cancer ***:By searching CNKI,Wanfang Data,PubMed,Web of Science,EMBASE and *** population-based survival studies of liver cancer from 1 January 2000 to 30 April 2020 were collected and evaluated by patient gender,time period,and *** overall or age-standardized five-year relative survival rate was used to describe the pattern and changes in liver cancer survival over the past ***:Globally,the highest age-standardized five-year relative survival rate was observed in Italy(18.0%,2005-2007)and the highest overall five-year relative survival rate was observed in Korea(34.6%,2012-2016),when compared to other *** most remarkable increase in overall five-year relative survival rate can be seen in Korea(from 10.7%during 1993-1995 to 34.6%during 2012-2016).In general,worldwide,the five-year relative survival rate of younger patients with liver cancer was higher than old *** most countries,the five-year relative survival rate of liver cancer was slightly higher in women than in *** China,the overall five-year relative survival rate of liver cancer in Taiwan was higher than that in other areas,while Cixian of Hebei and Qidong of Jiangsu were ***:Over the past decades,the survival rates of liver cancer have gradually improved,but great variations are also observed ***,younger patients with liver cancer have experienced a better *** disparity in liver cancer survival was not obvious.

关键词： Primary liver cancer relative survival rate prognosis population-based study cancer registration

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Pause electrolysis for acidic CO_(2) reduction on 3-dimensional Cu

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Materials Reports(Energy) 2023年第1期3卷 93-99,I0003页

作者： Zhanyou Xu Yi Xie ying Wang Department of Chemistry The Chinese University of Hong KongHong Kong S.A.R.China

Electrochemical CO_(2) reduction reaction(CO_(2) RR)exhibits remarkable potential in producing valuable chemicals with renewable *** CO_(2) RR in acidic media is beneficial to solve the issue of low carbon utilization brought by(bi)carbonate formation at the *** the competing hydrogen evolution reaction and achieving stable CO_(2) RR performance remains ***,we constructed a 3-dimensional Cu(3D-Cu)gas diffusion electrode(GDE)to achieve efficient C_(2)H_(4) production with a partial current density(j C_(2)H_(4))of over 470 mA cm^(2) and a Faradaic efficiency(FE C_(2)H_(4)) of 40%.With pause electrolysis,the decay rate of the j C_(2)H_(4) is only half that of the traditional constant *** GDE after constant electrolysis was found to suffer from severe salt formation,leading to the decreased activity and poor stability.

关键词： CO_(2) reduction reaction(CO_(2)RR) 3D-Cu electrode Acidic media Pause electrolysis

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平切图大坝地质三维建模及剖切分析

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测绘科学 2012年第5期37卷 78-80页

作者：魏占营中国测绘科学研究院北京100039

利用剖面图进行地质体建模因其复杂度很高,常常是利用CAD或类似的地质建模软件进行交互式的建模,因此非常耗时。本文以大坝地质平切图(剖面图的一种)为数据源,开发了一种"多段连接"的方法可以自动构建地质体的三维表面模型,以及一种"三... 详细信息

利用剖面图进行地质体建模因其复杂度很高,常常是利用CAD或类似的地质建模软件进行交互式的建模,因此非常耗时。本文以大坝地质平切图(剖面图的一种)为数据源,开发了一种"多段连接"的方法可以自动构建地质体的三维表面模型,以及一种"三次搜索法"用于模型剖切分析,并在实际项目中验证了本文方案的有效性。

关键词：地质体平切图三维建模剖切分析

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坚守与平衡——由curator职能之流变试析博物馆策展人核心职能的优化

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中国博物馆 2020年第4期 49-54页

作者：魏颖湖南省博物馆近现代藏品研究展示中心长沙410005

西方博物馆界curator职能的历史演变进程,折射出西方博物馆发展成熟的大致轨迹。通过分析时代、社会、科技、经济的发展对curator权责范围扩大与职能泛化的影响,剖析curator核心职能之所在;结合curator中文译介人的初衷与当今中国博物... 详细信息

西方博物馆界curator职能的历史演变进程,折射出西方博物馆发展成熟的大致轨迹。通过分析时代、社会、科技、经济的发展对curator权责范围扩大与职能泛化的影响,剖析curator核心职能之所在;结合curator中文译介人的初衷与当今中国博物馆语境中"策展人"的实际职能,分析"curator"与"策展人"两词间的辩证关系;并以其相同的核心职能为基础,从机构设置、藏品清查、多维阐释、权力平衡等方面谈中国博物馆策展人职能优化之道。

关键词：博物馆 Curator 策展人核心职能藏品

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Cell surface clustering of Cadherin adhesion complex induced by antibody coated beads

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Chinese Science Bulletin 2000年第16期45卷 1504-1509页

作者： Wenjun Zhang Zhongxiang Lin ying Hu Beijing Med Univ Beijing Inst Canc Res Sch Oncol Beijing 100034 Peoples R China

Cadherin receptors mediate cell-cell adhesion, signal transduction and assembly of cytoskeletons. How a single transmembrane molecule Cadherin can be involved in multiple functions through modulating its binding activities with many membrane adhesion molecules and cytoskeletal components is an unanswered question which can be elucidated by clues from bead experiments. Human lung cells expressing N-Cadherin were examined. After co-incubation with anti-N-Cadherin monoclonal antibody coated beads, cell surface clustering of N-Cadherin was induced. Immunofluorescent detection demonstrated that in addition to Cadherin, β-Catenin, α-Catenin, a-Actinin and Actin fluorescence also aggregated respectively at the membrane site of bead attachment. Myosin heavy chain (MHC), another major component of Actin cytoskeleton, did not aggregate at the membrane site of bead attachment. Adhesion unrelated protein Con A and polylysine conjugated beads did not induce the clustering of adhesion molecules. It is indicated

关键词： Latex bead N-Cadherin adherens junction adhesion molecular complex.

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High Performance Polymer Field-Effect Transistors Based on Thermally Crosslinked Poly(3-hexylthiophene)

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Chinese Physics Letters 2011年第11期28卷 264-267页

作者： JIang Chun-Xia Yang Xiao-Yan ZHAO Kai WU Xiao-Ming Yang Li-ying CHENG Xiao-Man wei Jun YIN Shou-Gen Key Laboratory of Display Materials and Photoelectric Devices(Ministry of Education) Tianjin University of TechnologyTianjin 300384 Institute of Material Physics and Tianjin Key Laboratory for Photoelectric Materials and DevicesTianjin University of TechnologyTianjin 300384 Singapore Institute of Manufacturing Technology 71 Nanyang DriveSingapore

The performance of polymer field-effect transistors is improved by thermal crosslinking of poly(3-hexylthiophene),using ditert butyl peroxide as the *** device performance depends on the crosslinker concentration *** obtain an optimal on/off ratio of 105 and the saturate field-effect mobility of 0.34 cm2V−1s−1,by using a suitable ratios of ditert butyl peroxide,0.5 wt%of poly(3-hexylthiophene).The microstructure images show that the crosslinked poly(3-hexylthiophene)active layers simultaneously possess appropriate crystallinity and smooth ***,crosslinking of poly(3-hexylthiophene)prevents the transistors from large threshold voltage shifts under ambient bias-stressing,showing an advantage in encouraging device environmental and operating stability.

关键词： stability morphology thiophene

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Meta-analysis reveals an association between acute pancreatitis and the risk of pancreatic cancer

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World Journal of Clinical Cases 2020年第19期8卷 4416-4430页

作者： Jie Liu ying Wang Yue Yu Department of Gastroenterology Affiliated Provincial HospitalAnhui Medical UniversityHefei 230001Anhui ProvinceChina Endoscopy Center Department The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230036Anhui ProvinceChina

BACKGROUND Chronic pancreatitis is associated with pancreatic cancer(PC),although the relationship between acute pancreatitis(AP)and the risk of PC remains unclear due to inconsistent and contradictory *** To conduct a meta-analysis of retrospective and prospective studies to explore the association between AP and PC *** We first searched original articles on the association of AP with PC using PubMed,Web of Science,Cochrane,and EMBASE *** we calculated the combined overall effect estimates(EEs)between AP and PC risk at a 95%confidence interval(CI)deploying a random-effects model,and assessed heterogeneity using the I2 *** combined relative risk with 95%CI was performed to examine the relationship between AP and *** bias and subgroup analyses were also ***,we performed sensitivity analysis to explain this *** Eleven studies were eligible for inclusion standards in this meta-analysis,resulting in pooled EEs of 2.07(95%CI:1.36-2.78)for AP and PC ***,five prospective cohort studies reported 103961 patients in the AP group,relative to 1442158 subjects in the control group,with a pooled relative risk of 7.81(95%CI:5.00-12.19).We also performed subgroup analyses using different follow-up times and type of research methods(case-control or cohort).Results from analyses of different follow-up times revealed the following pooled effect values:1-year lag period(EEs=23.47,95%CI:3.26-43.68),2-year lag period(EEs=9.82,95%CI:3.01-16.64),5-year lag period(EEs=2.47,95%CI:1.93-3.02),10-year lag period(EEs=1.69,95%CI:1.26-2.11),and>10-year lag period(EEs=1.17,95%CI:0.78-1.57).With regards to the methods,the case-control studies recorded EEs=3.03(95%CI:-1.02 to 7.08),whereas cohort studies had EEs=2.09(95%CI:1.22-2.97)pooled effect *** Overall,our findings indicated an association between AP and PC *** on subgroup analyses,AP is unlikely to be a causal factor for PC.

关键词： Acute pancreatitis Pancreatic cancer Meta-analysis

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Genotype-phenotype correlations of amyotrophic lateral sclerosis

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Translational Neurodegeneration 2016年第1期5卷 18-27页

作者： Hong-Fu Li Zhi-ying Wu Department of Neurology and Research Center of Neurology in Second Affiliated Hospital and the Collaborative Innovation Center for Brain ScienceZhejiang University School of Medicine88 Jiefang RdHangzhou 310009China

Amyotrophic lateral sclerosis(ALS)is a devastating neurodegenerative disease characterized by progressive neuronal loss and degeneration of upper motor neuron(UMN)and lower motor neuron(LMN).The clinical presentations of ALS are heterogeneous and there is no single test or procedure to establish the diagnosis of *** cases are diagnosed based on symptoms,physical signs,progression,EMG,and tests to exclude the overlapping *** ALS represents about 5~10% of ALS cases,whereas the vast majority of patients are *** date,more than 20 causative genes have been identified in hereditary *** the pathogenic mutations or risk variants for each ALS individual is ***,ALS patients carrying some specific mutations or variant may exhibit subtly distinct clinical *** the respective genotype-phenotype correlation has important implications for the genetic *** this review,we will delineate the clinical features of ALS,outline the major ALS-related genes,and summarize the possible genotype-phenotype correlations of ALS.

关键词： Amyotrophic lateral sclerosis Diagnosis of ALS Causative genes Genetic explanations Genotypephenotype correlations

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Application of ultrasound contrast in identification and diagnosis of ocular spaceoccupying lesions

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International Journal of Ophthalmology(English edition) 2011年第4期4卷 337-342页

作者： Jia-ying Yuan, Yun-Tao Zhang Department of Ultrasonography Hospital of Military Area of He'nan Zhengzhou 450003 He'nan Province China The Faculty of Biomedical Engineering of Zhengzhou University Zhengzhou 450001 He'nan Province China Department of Ultrasonography Xi'an Electricity Hospital Xi'an 710032 Shaanxi Province China Department of Urology Surgery Xijing Hospital the Fourth Military Medical University Xìan 710032 Shaanxi Province China

AIM: To analyze the application significance of ultrasound contrast agent in identification and diagnosis of ocular spaceoccupying lesions, and mainly analyze its advantages and problems. METHODS: Thirty-two representative literatures about the application of ultrasound contrast agent in diagnosis of spaceoccupying lesions at home and abroad were collected after focused on sorting the literature reporting the application of ultrasound contrast diagnostic technology in the diagnosis and identification of ocular spaceoccupying lesions in recent years. Its advantages and problems were retrospectively analyzed, and reasonable assessment on Existing problems was made and possible solutions to the problems were proposed. RESULTS: As a new imaging diagnostic technique, the contrast-enhanced ultrasound, which can enhance the display of tumor microcirculation vessels and improve the tumor's ultrasound diagnostic capability, was analyzed. Through sorting and comprehensively analyzing the collected literatures, the positive rate of ocular spaceoccupying lesion diagnosis could be significantly improved with ultrasound contrast technology. Thus, the vascular perfusion in normal tissues and lesions was reflected objectively. According to the lesion's perfusion characteristics of the contrast agent plus with the performance features of two-dimensional ultrasound, the ocular spaceoccupying lesions can be accurately diagnosed, and this could provide clinicians with reliable research basis in this field. CONCLUSION: Ultrasound contrast examination is a new testing method, and ultrasound contrast agent can significantly enhance the ultrasonic detection signal, clearly show the blood perfusion in vessels and tissues, increase the image contrast resolution, and improve the lesion's detection capability in the microcirculation perfusion level, especially its important value in the diagnosis of ocular tumor.

关键词： ultrasound contrast ocular spaceoccupying lesion differential diagnosis new microbubble contrast agent

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Comprehensive Evaluation of Tahe Medium Gravity Crude

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China Petroleum Processing & Petrochemical Technology 2008年第2期10卷 11-17页

作者： Li Li Zou ying Weng Huixin College of Chemical Engineering East China University of Science and Technology Shanghai 200237 SINOPEC Production Management Department

The comprehensive evaluation of Tahe medium gravity crude has demonstrated that this type of crude belongs to a intermediate base sour crude, featuring high vanadium content (103ppm), high carbon residue content, low pour point, and low acid value. Based on the crude processing conditions at SINOPEC Luoyang Petrochemical Branch Company, a proposal on the appropriate process flow scheme for processing Tahe crude oil has been raised with the main ideas presented as follows. The IBP-175 fraction is not an ideal feedstock for catalytic reforming; the 75-250 fraction is a qualified feedstock for zeolite de-waxing; the 140-230 fraction can be used to manufacture the No. 3 jet fuel through appropriate distillation range adjustment and product refining; the 175-350 fraction can be directly used to manufacture No.-10 diesel through proper refining; the atmospheric resid boiling over 350 is not suited to be used as the RFCC feedstock; the 350-520 vacuum distillate oil can be used as the FCC feedstock; and the vacuum residuum boiling over 520 is a good feedstock for manufacture of asphalt.

关键词： medium gravity Tahe crude evaluation process scheme

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