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CT diagnosis of 52 patients with lymphoma in abdominal lymph nodes

World Journal of Gastroenterology 2006年第48期12卷 7869-7873页

作者： Ri-Sheng Yu wei-min Zhang yi-Qing Liu Department of Radiology Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310009 Zhejiang Province China

AIM： To assess CT manifestations and its diagnostic value for lymphoma in the abdominal lymph nodes （LALN）.METHODS： CT findings in 52 cases of LALN proved by surgery or biopsy, including Hodgkin＇s disease （HD） in 16 cases and non-Hodgkin＇s lymphoma （NHL） in 36 cases, were retrospectively analyzed.RESULTS：（1） CT manifestations based on distribution of the lesions of LALN： Solitary mass type was found in 10 cases, including solitary, round, uniform-density, enlarged lymph nodes in 3 cases; and multiple, enlarged lymph nodes fusing into singular Iobular mass in 7 cases. Thirty-feur cases of multiple-nodular type showed multiple, round, enlarged lymph nodes with uniform density and clear margins. Vessels-embedded signs, including mesenteric vessels, renal vessels, abdominal aorta or inferior vena cava, were seen in 6 cases, and duodenum-embedded signs were seen in 2 cases. Eight cases of diffuse type showed characteristic ＂cobblestone signs＂. （2） CT manifestations correlated with pathological type： CT manifestations of 12 cases of HD were different from those of 40 cases of NHL in distribution, size, quantity and fused lesion of enlarged lymph nodes. （3） Twenty-eight cases of 52 patients were accompanied with extra-nodal lymphoma in the abdomen, especially gastrointestinal lymphoma, which had characteristic CT findings. （4） In follow-up examinations, CT images showed uniform, heterogeneous or rim enhancement in 15 cases, and occasional calcifications accompanied with reduction of the lesion size and quantity in 12 cases, whereas the lesions disappeared in 3 cases after treatment.CONCLUSION： CT images show many characteristic manifestations valuable for qualitative diagnosis of LALN, and it is also helpful for pathological classification of LALN and therapeutic evaluation in follow-up of patients.

关键词： Lymphoma Lymph nodes Computed tomography Diagnosis Classification

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Optical multi-color monitoring of OJ 287 from 2006 to 2012

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Research in Astronomy and Astrophysics 2017年第8期17卷 57-68页

作者： Qian Guo Ding-Rong Xiong Jin-ming Bai Xu-Liang Fan wei-min yi Yunnan Observatories Chinese Academy of Sciences Kunming 650216 China Key Laboratory for the Structure and Evolution of Celestial Objects Chinese Academy of Sciences Kunming 650216 China Center for Astronomical Mega-Science Chinese Academy of Sciences Beijing 100012 China University of Chinese Academy of Sciences Beijing 100049 China

We present our optical multi-color monitoring of the BL Lac object OJ 287 from January 2006to December 2012 in the V,R and I bands.A relatively active state in OJ 287 has been found over all monitored epochs,among which the variations of average magnitude in V/R/I bands were measured with ?V=1.956 mag,?R=2.067 mag and ?I=2.115 mag,*** reliable intraday variability is detected,but possible variability is detected on 16 *** relative variation amplitudes fall into the range between 1% and 8%,with the majority between 2% and 4%.No time lags have been detected,but strong correlations exist among light curves in the three *** bluer-when-brighter trend is dominant over intraday timescales,which supports the shock-in-jet *** combining with additional V/R band data obtained from SMARTS and the Steward Observatory,we also find a bluer-when-brighter trend over a long-term *** possible periods of 513,176,36,30,26,17 and 14 d are found in all time-series data sets from 2006 to *** explanations about these periods are given.

关键词： BL Lacertae objects individual(OJ 287)—galaxies active—galaxies photometry

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Photoinduced bismuth vanadate-catalyzed C(sp^(2))-H functionalization

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Chinese Chemical Letters 2024年第3期35卷 1-2页

作者： Rong-Nan yi wei-min He Key Laboratory of Food&Environment&Drug Monitoring and Testing of Universities in Hunan Province Hunan Police AcademyChangsha 410138China School of Chemistry and Chemical Engineering University of South ChinaHengyang 421001China

Visible light-induced organic reactions have gained much attention in recent years due to their mild conditions and high efficiency[1,2].In this context,many efficient photocatalysts including transition metal complex... 详细信息

关键词： bismuth catalyzed gained

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Effect of cocaine on germ cell apoptosis in rats at different ages

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Asian Journal of Andrology 2006年第5期8卷 569-575页

作者： Guo-Sheng Yang wei Wang yi-min Wang Zhao-Dian Chen Shuo Wang Jia-Jie Fang Department of Urology First Affiliated Hospital College of Medicine Zhejiang University Hangzhou 310003 China

Aim： To investigate the effect of cocaine on apoptosis and caspase-3 activity in germ cells in male rats at different ages. Methods： Cocaine hydrochloride was given （15 mg/kg body weight s.c.） to male Sprague-Dawley rats of 3 weeks （n = 8）, 6 weeks （n = 8） and 12 weeks （n = 8） of age, daily for 28 days. The serum levels of follicle stimulating hormone （FSH）, luteinizing hormone （LH）, prolactin （PRL）, testosterone （T） and estrogen （E2） were assayed, and the DNA fragmentation of germ cells was determined by gel eletronphoresis. The cell cycle, apoptosis and caspase-3 activity of germ cells were tested by flow cytometry. Results： After the 28-day cocaine treatment, testes weight of the 3-week-old rats, the testes and body weights of the 6-week-old rats were decreased significantly compared to those of their corresponding controls （P 〈 0.05）. The serum level of T was decreased significantly in the 3-week-old and 6-week-old rats, and the serum level of PRL was also decreased significantly in 12-week-old rats compared to the controls （P 〈 0.05）, In all the three cocaine-treated groups, the isolated DNA displayed a clear ladder pattern, especially in the 6-week old rats. The number of apoptosic germ cells increased significantly in 3- and 6- week-old rats treated with cocaine （P 〈 0.05）. The caspase-3 activity in all three groups increased significantly compared to the controls （P 〈 0.05）, especially in the 6-week-old rats. Conclusion： Cocaine exposure for 28 days leads to significant damage to male gonad and apoptosis elevation in testes of rats of different ages, especially in those of 6 weeks of age. The increase in caspase-3 activity might be a key pathway related to the early stage of apoptosis as the mechanism of cocaine-induced germ cell loss.

关键词： cocaine testis apoptosis caspase-3 germ cell

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Photocatalytic minisci-type multicomponent reaction for the synthesis of 1-(halo)alkyl-3-heteroaryl bicyclo[1.1.1] pentanes

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Chinese Chemical Letters 2024年第10期35卷 6-8页

作者： Rong-Nan yi wei-min He Key Laboratory of Food&Environment&Drug Monitoring and Testing of Universities in Hunan Province Hunan Police Academy.Changsha 410138China School of Chemistry and Chemical Engineering University of South ChinaHengyang 421001China

Bioisosteres play an important role in pharmaceutical and agricultural compound design that has been developed to enhance the properties of *** a sp3-rich small ring cage hydrocarbons,bicyclo[1.1.1]pentanes(BCPs)were commonly considered as a bioisostere of the para-substituted arenes,internal alkynes,and tert-butyl groups,and its introduction can significantly improve pharmacokinetic properties,including passive permeability,aqueous solubility,metabolic stability[1].Over the past decades,numerous pharmaceutically relevant molecules with biaryl frameworks were improved by the approach of bioisosteric *** strategies for the synthesis of such BCP-aryls derivatives mostly depend on the stepwise C-C formation via the direct addition to bridgehead C-C bond of[1.1.1]propellane to provide active BCP-intermediates and followed by a second transitionmetal cross-coupling ***,these pioneer works were limited by the low step economy,the use of unstable reagents,and harsh conditions in industrial productions.

关键词： synthesis substituted alkyl

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Reporter Gene Assay for Detection of Shellfish Toxins

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Biomedical and Environmental Sciences 2009年第5期22卷 419-422页

作者： wei-DONG YANG min-yi WU JIE-SHENG LIU XI-CHUN PENG HONG-YE LI School of Life Science and Technology Jinan UniversityGuangzhou 510632GuangdongChina

Objective To explore the potential reporter gene assay for the detection of sodium channel-specific toxins in shellfish as an alternative for screening harmful algal bloom (HAB) toxins, considering the fact that the existing methods including HPLC and bioassay are inappropriate for identifying HAB toxins which poses a serious problem on human health and shellfish industry. Methods A reporter plasmid pEGFP-c-fos containing c-fos promoter and EGFP was constructed and transfected into T24 cells using LipofectAminE 2000. Positive transfcctants were screened by G418 to produce a pEGFP-c-fos-T24 cell line. After addition of increasing neurotoxic shellfish poison (NSP) or GTX2,3, primary components of paralytic shellfish poison (PSP), changes in expression of EGFP in the cell line were observed under a laser scanning confocal microscope and quantified with Image-pro Plus software. Results Dose-dependent changes in the intensity of green fluorescence were observed for NSP in a range from 0 to 10 ng/mL and for GTX2,3 from 0 to 16 ng/mL. Conclusion pEGFP-c-fos-T24 can be applied in detecting HAB toxins, and cell-based assay can be used as an alternative for screening sodium channel-specific HAB toxins.

关键词： Shellfish poisoning Green fluorescent protein Harmful algal bloom toxins

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Research on a TOPSIS energy efficiency evaluation system for crude oil gathering and transportation systems based on a GA-BP neural network

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Petroleum Science 2024年第1期21卷 621-640页

作者： Xue-Qiang Zhang Qing-Lin Cheng wei Sun yi Zhao Zhi-min Li Key Lab of ministry of Education for Enhancing the Oil and Gas Recovery Ratio Northeast Petroleum UniversityDaqing163318HeilongjiangChina China Petroleum Pipeline Material and Equipment Co. LtdLangfang065000HebeiChina Research Institute of Petroleum Engineering and Technology Sinopec Northwest Oilfield CompanyUrumqi830011XinjiangChina

As the main link of ground engineering,crude oil gathering and transportation systems require huge energy consumption and complex *** is necessary to establish an energy efficiency evaluation system for crude oil gathering and transportation systems and identify the energy efficiency *** this paper,the energy efficiency evaluation system of the crude oil gathering and transportation system in an oilfield in western China is *** with the big data analysis method,the GA-BP neural network is used to establish the energy efficiency index prediction model for crude oil gathering and transportation *** comprehensive energy consumption,gas consumption,power consumption,energy utilization rate,heat utilization rate,and power utilization rate of crude oil gathering and transportation systems are *** the efficiency and unit consumption index of the crude oil gathering and transportation system,the energy efficiency evaluation system of the crude oil gathering and transportation system is established based on a game theory combined weighting method and TOPSIS evaluation method,and the subjective weight is determined by the triangular fuzzy analytic hierarchy *** entropy weight method determines the objective weight,and the combined weight of game theory combines subjectivity with objectivity to comprehensively evaluate the comprehensive energy efficiency of crude oil gathering and transportation systems and their ***,the weak links in energy utilization are identified,and energy conservation and consumption reduction are *** above research provides technical support for the green,efficient and intelligent development of crude oil gathering and transportation systems.

关键词： Crude oil gathering and transportation system GA-BP neural network Energy efficiency evaluation TOPSIS evaluation method Energy saving and consumption reduction

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Discovery of six high-redshift quasars with the Lijiang 2.4 m telescope and the Multiple Mirror Telescope

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Research in Astronomy and Astrophysics 2012年第9期12卷 1185-1190页

作者： Xue-Bing Wu Wen-Wen Zuo Qian Yang wei-min yi Chen-wei Yang Wen-Juan Liu Peng Jiang Xin-Wen Shu Hong-Yan Zhou Department of Astronomy Peking University Beijing 100871 China wuxb @*** National Astronomical Observatories / Yunnan Astronomical Observatory Chinese Academy ofSciences Kunming 650011 China Key Laboratory for Research in Galaxies and Cosmology The University of Science andTechnology of China Chinese Academy of Sciences Hefei 230026 China Polar Research Institute of China Shanghai 200136 China

Quasars with redshifts greater than 4 are rare, and can be used to probe the structure and evolution of the early universe. Here we report the discovery of six new quasars with i-band magnitudes brighter than 19.5 and redshifts between 2.4 and 4.6 from spectroscopy with the Yunnan Faint Object Spectrograph and Camera (YFOSC) at the Lijiang 2.4 m telescope in February, 2012. These quasars are in the list of z > 3.6 quasar candidates selected by using our proposed J K/i Y criterion and the photometric redshift estimations from the SDSS optical and UKIDSS near-IR photometric data. Nine candidates were observed by YFOSC, and five among six new quasars were identified as z > 3.6 quasars. One of the other three objects was identified as a star and the other two were unidentified due to the lower signal-to-noise ratio of their spectra. This is the first time that z > 4 quasars have been discovered using a telescope in China. Thanks to the Chinese Telescope Access Program (TAP), the redshift of 4.6 for one of these quasars was confirmed by the Multiple Mirror Telescope (MMT) Red Channel spectroscopy. The continuum and emission line properties of these six quasars, as well as their central black hole masses and Eddington ratios, were obtained.

关键词： quasars: general — quasars: emission lines — galaxies: active — galax- ies: high-redshift

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World Journal of Gastrointestinal Oncology 2024年第2期16卷 458-474页

作者： wei Ding wei-wei Chen yi-Qin Wang Xue-Zhong Xu yi-Bo Wang Yong-min Yan Yu-Lin Tan Department of General Surgery Wujin Hospital Affiliated with Jiangsu UniversityChangzhou 213003Jiangsu ProvinceChina Changzhou Medical Center Nanjing Medical UniversityChangzhou 213017Jiangsu ProvinceChina Department of General Surgery The Wujin Clinical College of Xuzhou Medical UniversityChangzhou 213003Jiangsu ProvinceChina

BACKGROUND Gastric cancer(GC)is a prevalent malignant tumor of the gastrointestinal ***710 is a transcription factor(TF),and zinc finger protein 710(ZNF710)-AS1-201 is an immune-related long noncoding RNA(lncRNA)that is upregulated in GC *** To assess the correlation between ZNF710-AS1-201 and immune microenvir-onment features and to investigate the roles of ZNF710-AS1-201 in the invasion and metastasis processes of GC *** We obtained data from The Cancer Genome Atlas and Wujin *** assessed cell growth,migration,invasion,and programmed cell death using cell counting kit-8,EdU,scratch,Transwell,and flow cytometry *** real-time polymerase chain reaction(qRT-PCR)was used to identify the potential downstream targets of *** In GC tissues with low ZNF710-AS1-201 expression,immunoassays detected significant infiltration of various antitumor immune cells,such as memory CD8 T cells and activated CD4 T *** the low-expression group,the half-maximal inhibitory concentrations(IC_(50)s)of 5-fluorouracil,cisplatin,gemcitabine,and trametinib were lower,whereas the IC_(50)s of dasatinib and vorinostat were *** malignant degree of GC was higher and the stage was later in the high-expression ***,patients with high expression of ZNF710-AS1-201 had lower overall survival and disease-free survival *** vitro,the overexpression of ZNF710-AS1-201 greatly enhanced growth,metastasis,and infiltration while suppressing cell death in HGC-27 *** contrast,the reduced expression of ZNF710-AS1-201 greatly hindered cell growth,enhanced apoptosis,and suppressed the metastasis and invasion of MKN-45 *** expression changes in ZNF710 were significant,but the corresponding changes in isocitrate dehydrogenase-2,Semaphorin 4B,ARHGAP10,RGMB,hsa-miR-93-5p,and ZNF710-AS1-202 were not consistent or statistically significant after overexpression or knockdown of ZNF710-AS1-201,as determined by ***

关键词： Gastric cancer ZNF710-AS1-201 Proliferation Metastasis Invasion Apoptosis

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In Situ Coupling of Highly Dispersed Ni/Fe Metal-NC Sites and N-Doped 3D Carbon Fibers Toward Free-Standing Bifunctional Cathode for Flexible Zinc-Air Battery

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Energy & Environmental Materials 2024年第1期7卷 121-130页

作者： Chenglong Lai Mengjun Li yi Shen min Zhou wei Wang Kai Jiang Haomiao Li Kangli Wang State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic EngineeringHuazhong University of Science and TechnologyWuhan 430074China School of Materials Science and Engineering Huazhong University of Science and TechnologyWuhanHubei 430074China Engineering Research Center of Power Safety and Efficiency Ministry of EducationWuhanHubei 430074China

Designing flexible free-standing air-electrode with efficient OER/ORR performance is of vital importance for the application of Zinc-air batteries in flexible ***,a flexible free-standing electrode(Ni/Fe-NC/NCF/CC)is synthesized by in-situ coupling of binary Ni/Fe-NC nanocubes and N-doped carbon nanofibers(NCF)rooted on carbon *** highly dispersed binary Ni/Fe-NC sites ensure excellent ORR activity and create efficient OER active sites relative to Ni-NC and *** in-situ coupling of Ni/Fe-NC and NCF constructs a 3D interconnected network structure that not only provides abundant and stabilized reactive sites but also guarantees fast electron transfer and gas transportation,thus achieving efficient and fast operation of ORR/***,Ni/Fe-NC/NCF/CC displays a much positive potential(0.952 V)at 4.0 mA cm^(-2)for ORR and a low OER overpotential(310 mV)at 50 mA cm^(-2).The Zinc-air battery with Ni/Fe-NC/NCF/CC air-electrode exhibits excellent battery performance with outstanding discharge/charge durability for 2150 *** flexible Zn-air batteries with foldable mechanical properties display a high power density of 105.0 mW cm^(-2).This work widened the way to prepare flexible bifunctional air-electrode by designing composition/structure and in-situ coupling.

关键词： binary Ni/Fe-NC sites in-situ coupling synergistic catalytic effect Zn-air battery

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