检索结果-南通市图书馆

An overview for monitoring and prediction of pathogenic microorganisms in the atmosphere

Fundamental Research 2024年第3期4卷 430-441页

作者： Jianping Huang Danfeng Wang Yongguan zhu Zifeng Yang Maosheng Yao Xiaoming Shi Taicheng An Qiang Zhang Cunrui Huang Xinhui Bi Jiang Li Zifa Wang Yongqin Liu Guibing zhu Siyu Chen Jian Hang Xinghua Qiu weiwei Deng Huaiyu Tian Tengfei Zhang Tianmu Chen Sijin Liu Xinbo Lian Bin Chen Beidou Zhang Yingjie Zhao Rui Wang Han Li Collaborative Innovation Center for Western Ecological Safety College of Atmospheric SciencesLanzhou UniversityLanzhou 730000China Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China National Clinical Research Center for Respiratory Disease Guangzhou Institute of Respiratory HealthFirst Affiliated Hospital of Guangzhou Medical UniversityState Key Laboratory of Respiratory Disease(Guangzhou Medical University)Guangzhou 510230China College of Environmental Sciences and Engineering Peking UniversityBeijing 100871China China CDC Key Laboratory of Environment and Population Health National Institute of Environmental HealthChinese Center for Disease Control and PreventionBeijing 100021China Guangdong-hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health School of Environmental Science and EngineeringInstitute of Environmental Health and Pollution ControlGuangdong University of TechnologyGuangzhou 510006China Ministry of Education Key Laboratory for Earth System Modeling Department of Earth System ScienceTsinghua UniversityBeijing 100084China Vanke School of Public Health Tsinghua UniversityBeijing 100084China State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Protection and Resources Utilization Guangzhou Institute of GeochemistryChinese Academy of SciencesGuangzhou 510640China National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Center for Pan-third Pole Environment Lanzhou UniversityLanzhou 730000China College of Atmospheric Sciences Lanzhou UniversityLanzhou 730000China School of Atmospheric Sciences Sun Yat-sen Universityand Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 510640

Corona virus disease 2019(COVID-19)has exerted a profound adverse impact on human *** have demonstrated that aerosol transmission is one of the major transmission routes of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Pathogenic microorganisms such as SARS-CoV-2 can survive in the air and cause widespread infection among *** monitoring of pathogenic microorganism transmission in the atmosphere and accurate epidemic prediction are the frontier guarantee for preventing large-scale epidemic *** of pathogenic microorganisms in the air,especially in densely populated areas,may raise the possibility to detect viruses before people are widely infected and contain the epidemic at an earlier *** multi-scale coupled accurate epidemic prediction system can provide support for governments to analyze the epidemic situation,allocate health resources,and formulate epidemic response *** review first elaborates on the effects of the atmospheric environment on pathogenic microorganism transmission,which lays a theoretical foundation for the monitoring and prediction of epidemic ***,the monitoring technique development and the necessity of monitoring pathogenic microorganisms in the atmosphere are summarized and ***,this review introduces the major epidemic prediction methods and highlights the significance to realize a multi-scale coupled epidemic prediction system by strengthening the multidisciplinary cooperation of epidemiology,atmospheric sciences,environmental sciences,sociology,demography,*** summarizing the achievements and challenges in monitoring and prediction of pathogenic microorganism transmission in the atmosphere,this review proposes suggestions for epidemic response,namely,the establishment of an integrated monitoring and prediction platform for pathogenic microorganism transmission in the atmosphere.

关键词： Aerosol transmission Epidemic monitoring methods Epidemic prediction modelsEpidemic response Multidisciplinary cooperation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

月球与行星科学多模态大模型的概念及应用初探

引用

矿物岩石地球化学通报 2024年第2期43卷 343-351页

作者：雷丹泓刘建忠朱凯刘敬稳任曼张圣张莉中国科学院地球化学研究所月球与行星科学研究中心贵阳550081 中国科学院比较行星学卓越创新中心合肥230026 中国科学院大学北京100049

自2022年底一系列大型语言模型(大模型)发布以来,以大模型为研究热点的新一代人工智能、(AI)技术在各行各业引起高度重视,随即出现的专业大模型更将重塑千行百业。月球与行星科学领域作为科学技术前沿的代表,建立该领域的专业大模型是... 详细信息

自2022年底一系列大型语言模型(大模型)发布以来,以大模型为研究热点的新一代人工智能、(AI)技术在各行各业引起高度重视,随即出现的专业大模型更将重塑千行百业。月球与行星科学领域作为科学技术前沿的代表,建立该领域的专业大模型是今后的必然趋势。本文在多模态大模型的基础上首次提出了月球与行星科学多模态大模型的概念,并从其定义、设计及应用场景等细节展开详细阐述和讨论。模型旨在帮助更多人认识月球并了解月球,同时协助更多学者处理并分析月球与行星数据,促进挖掘月球与行星大数据间的隐式或非线性关系,主动发现并解决未知科学问题,率先推动大数据驱动科学发现这一新的研究范式在行星科学领域落地生根。

关键词：月球与行星科学多模态大模型大数据人工智能

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Analytical model and application of stress distribution on mining coal floor

引用

Journal of China University of Mining and Technology 2008年第1期18卷 13-17页

作者： zhu Shu-yun JIAN Zhen-quan HOU hong-liang XIAO wei-guo YAO Pu School of Resources and Earth Science China University of Mining ＆ Technology Xuzhou Jiangsu 221008 China Department of Prevention and Treatment for Coal Mine Water Zhengzhou Coal Group Ltd Co Xinmi Henan 452371 China

Given the analysis of underground pressure, a stress calculation model of coal floor stress has been established based on a theory of elasticity. The model presents the law of stress distribution on the relatively fixed position of the mining coal floor： the extent of stress variation in a fixed floor position decreases gradually along with depth, the decreasing rate of the vertical stress is clearly larger than that of the horizontal stress at a specific depth. The direction of the maximum principal stress changes gradually from a vertical direction to a horizontal direction with the advance of the working face. The deformation and permeability of the rock mass of the coal floor are obtained by contrasting the difference of the principal stress established from theoretical calculations with curves of stress-strain and permeability-strain from tests, which is an important mechanical basis for preventing water inrush from confined aauifers.

关键词： model coal floor stress distribution analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

桥墩形式对连续刚构桥地震响应的影响

引用

工程与建设 2024年第4期38卷 948-950,954页

作者：朱峰李红张霖波武汉理工大学交通与物流工程学院湖北武汉430063

为了研究桥墩形式对高墩大跨度连续刚构桥地震响应的影响,本文以某桥为例,采用有限元分析软件MIDAS Civil建模并分析了3种不同桥墩形式对桥梁结构自振频率的影响;根据场地条件,通过地震波生成软件生成3条随机地震波,并对桥梁进行E2地震... 详细信息

为了研究桥墩形式对高墩大跨度连续刚构桥地震响应的影响,本文以某桥为例,采用有限元分析软件MIDAS Civil建模并分析了3种不同桥墩形式对桥梁结构自振频率的影响;根据场地条件,通过地震波生成软件生成3条随机地震波,并对桥梁进行E2地震作用下时程分析。分析结果表明:在低阶振型下组合式桥墩频率比空心墩和双肢墩分别低42%与38%,说明桥墩形式显著影响50 m以上高墩的刚性;在地震作用下,双肢薄壁墩在横向作用下的水平向弯矩比另两种最多降低了75%,说明在高墩条件下,双肢薄壁墩抵抗横向地震作用的能力要显著提高。说明在山区高地震烈度地带,若拟建桥梁墩高超过50 m,选用双肢薄壁墩可以作为较优解。

关键词：高墩刚构桥梁大跨度桥墩形式时程分析

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

蜂蜜抗炎作用的研究进展

引用

食品工业科技 2024年第14期45卷 426-434页

作者：朱文振范营营谢绍华朱艳萍玄红专聊城大学生命科学学院山东聊城252059 聊城市人民医院儿科山东聊城252000

蜂蜜是由蜜蜂生产的天然产物,长期以来作为食品在世界范围内被人们普遍食用。蜂蜜具有抗炎作用,这与蜂蜜的抗菌和抗氧化功能是密切相关的。对蜂蜜抗炎功能的探究涉及两个方面:一方面基础研究探索蜂蜜生物学功能的分子机制并明确有效成分... 详细信息

蜂蜜是由蜜蜂生产的天然产物,长期以来作为食品在世界范围内被人们普遍食用。蜂蜜具有抗炎作用,这与蜂蜜的抗菌和抗氧化功能是密切相关的。对蜂蜜抗炎功能的探究涉及两个方面:一方面基础研究探索蜂蜜生物学功能的分子机制并明确有效成分;另一方面则通过临床研究评估蜂蜜对炎症性疾病的改善效果。基础研究揭示了蜂蜜发挥抗炎作用的关键有效成分,并进一步阐明了相关的分子机制。蜂蜜的抗炎功能与其含有的黄酮类化合物、酚酸、葡萄糖氧化酶、过氧化氢和甲基乙二醛密切相关,这些有效成分主要通过调控免疫细胞功能、调节炎症细胞因子水平、抑制致病菌生长和抗氧化而发挥作用。蜂蜜能减轻消化道炎症、改善肠道菌群、缓解慢性鼻窦炎症状以及预防和治疗放射性口腔炎。本文以近5年蜂蜜相关的研究为主,综述了蜂蜜抗炎作用的机制和关键有效成分的功能,以及目前蜂蜜在炎症性疾病领域的应用。

关键词：蜂蜜抗炎活性机制成分炎症性疾病

来源：

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

基于转录组测序挖掘疣吻沙蚕性腺发育相关基因

引用

南方农业学报 2024年第3期55卷 623-637页

作者：赵玉薇黄成唐驰鹏朱鹏张虹杨家林许尤厚李万就刘芳星广西北部湾海洋生物多样性养护重点实验室(北部湾大学) 广西钦州535011 广西桂海创业服务有限公司广西钦州538001 广西钦州市钦南区农业农村局广西钦州535009

【目的】鉴定筛选出与疣吻沙蚕性腺发育相关的候选基因及信号通路,揭示其性别分化及变态的分子调控机制,为疣吻沙蚕大规模人工繁育技术的突破提供理论依据。【方法】以成熟雄性(M)、成熟雌性(F)和未变态疣吻沙蚕(R)为研究对象,通过Illum... 详细信息

【目的】鉴定筛选出与疣吻沙蚕性腺发育相关的候选基因及信号通路,揭示其性别分化及变态的分子调控机制,为疣吻沙蚕大规模人工繁育技术的突破提供理论依据。【方法】以成熟雄性(M)、成熟雌性(F)和未变态疣吻沙蚕(R)为研究对象,通过Illumina NovaSeq 6000平台完成高通量转录组测序,经过滤、质量控制及拼接组装后,依据FoldChange≥2且错误发现率(FDR)<0.01的筛选标准,通过DESeq2筛选出差异表达基因(DEGs),然后进行GO功能注释分析和KEGG信号通路富集分析,并以实时荧光定量PCR对转录组测序结果进行验证。【结果】经转录组测序从9个疣吻沙蚕样品中获得46891条Unigenes,在COG、GO、KEGG、KOG、Pfam、Swiss-Prot、TrEMBL、eggNOG和Nr等9个主要功能数据库中有27878条Unigenes得到注释。依据筛选标准,共筛选出1798个DEGs,其中,M vs F组有349个DEGs,R vs F组有1090个DEGs,R vs M组有359个DEGs。GO功能注释分析发现,DEGs主要注释到细胞、细胞部分、结合、细胞过程、单生物过程等GO功能条目;KEGG信号通路富集分析结果表明,DEGs主要富集在氧化磷酸化、花生四烯酸代谢、视黄醇代谢、甘氨酸/丝氨酸/苏氨酸代谢等信号通路上。综合DEGs的KEGG信号通路富集分析及Nr数据库BLASTx比对分析,最终筛选出DMRT1、SOX7、HSP90、CALM等14个与疣吻沙蚕性腺发育相关的DEGs。实时荧光定量PCR检测的目的基因表达趋势与转录组测序分析结果基本一致,进一步证实转录组测序结果的准确性。【结论】疣吻沙蚕的性腺发育和成熟机制与多基因发挥功能及多个信号通路相关,包括雄性个体偏向MT-CYB、HSP60和DNAH5等基因,雌性个体偏向HSP90、SOX7和COL1A1等基因,以及氧化磷酸化、花生四烯酸代谢、视黄醇代谢、甘氨酸/丝氨酸/苏氨酸代谢等与性腺发育相关的信号通路。

关键词：疣吻沙蚕性腺发育差异表达基因(DEGs) 转录组测序

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

四网融合条件下以客流需求为导向的市域铁路运输组织优化建议

引用

城市轨道交通研究 2024年第4期27卷 1-4页

作者：柏成刘裕行张炜晗朱炜滕靖同济大学交通运输工程学院上海201804 上海市轨道交通结构耐久与系统安全重点实验室上海201804

[目的]区域一体化建设对区域多层次轨道交通网络的融合发展提出了更高的要求。在四网融合趋势下,应充分考虑客流需求,以客流需求为导向进行市域铁路的运输组织优化。[方法]从长江三角洲等区域轨道交通四网融合背景和市域铁路在其中的功... 详细信息

[目的]区域一体化建设对区域多层次轨道交通网络的融合发展提出了更高的要求。在四网融合趋势下,应充分考虑客流需求,以客流需求为导向进行市域铁路的运输组织优化。[方法]从长江三角洲等区域轨道交通四网融合背景和市域铁路在其中的功能定位出发,明确了轨道交通互联互通的内涵。从客运需求总量、市域铁路客流分担率、运力供给和客运需求的匹配性3个方面阐述了当前市域铁路面临的运输组织困境。以客流需求为导向,从战略层、策略层及运营层3个层面提出了市域铁路运输组织的优化建议。[结果及结论]当前市域铁路运输组织的3大制约因素分别为线路规划建设与客运需求的差异、市域铁路与其他运输方式竞争优势不明显、缺少客流导向的列车开行方案调整机制及方法。从战略层角度应强化顶层设计,形成一体化运输组织体系;从策略层角度应化竞为合,发挥多模式轨道交通网络化效应;从运营层角度应以人为本,实行多样化行车组织模式。

关键词：市域铁路四网融合区域交通一体化客流需求导向运输组织优化

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An allelic variation in the promoter of the LRR-RLK gene,qSS6.1,is associated with melon seed size

引用

Journal of Integrative Agriculture 2024年第10期23卷 3522-3536页

作者： Xiaoxue Liang Jiyu Wang Lei Cao Xuanyu Du Junhao Qiang Wenlong Li Panqiao Wang Juan Hou Xiang Li Wenwen Mao Huayu zhu Luming Yang Qiong Li Jianbin Hu College of Horticulture Henan Agricultural UniversityZhengzhou 450002China Henan Engineering Research Center for Cucurbit Germplasm Enhancement and Utilization Zhengzhou 450002China International Joint Laboratory of Henan Horticultural Crop Biology Zhengzhou 450002China

Seed size is an important agronomic trait in melons that directly affects seed germination and subsequent seedling ***,the genetic mechanism underlying seed size in melon remains *** the present study,we employed Bulked-Segregant Analysis sequencing(BSA-seq)to identify a candidate region(~1.35 Mb)on chromosome 6 that corresponds to seed *** interval was confirmed by QTL mapping of three seed size-related traits from an F2 population across three *** mapping region represented nine QTLs that shared an overlapping region on chromosome 6,collectively referred to as *** InDel markers were developed in the qSS6.1 region,narrowing it down to a 68.35 kb interval that contains eight annotated *** variation analysis of the eight genes identified a SNP with a C to T transition mutation in the promoter region of MELO3C014002,a leucine-rich repeat receptor-like kinase(LRR-RLK)*** mutation affected the promoter activity of the MELO3C014002 gene and was successfully used to differentiate the large-seeded accessions(C-allele)from the small-seeded accessions(T-allele).qRT-PCR revealed differential expression of MELO3C014002 between the two parental *** predicted protein has typical LRR-RLK family domains,and phylogenetic analyses reveled its similarity with the homologs in several plant ***,these findings suggest MELO3C014002 as the most likely candidate gene involved in melon seed size *** results will be helpful for better understanding the genetic mechanism regulating seed size in melons and for genetically improving this important trait through molecular breeding pathways.

关键词： melon QTL mapping seed size candidate gene allelic variation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An organic visible-photocatalytic-adsorbence mechanism to high-efficient removal of heavy metal antimony ions

引用

Materials Reports(Energy) 2024年第3期4卷 49-59页

作者： Linji Yang Ke Sun Tao Liu Ciyuan Huang Libin Zhang Yang Zhou Kai Chen Shangfei Yao Ziyang Zhang Chenfu Zhao hongxiang zhu Bingsuo Zou Shuangfei Wang Dongfeng Xue School of Chemistry and Chemical Engineering Guangxi Key Laboratory of Processing for Non-ferrous Metals and Featured MaterialsState Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite StructuresSchool of ResourcesEnvironment and MaterialsGuangxi UniversityNanning 530004China Department of Biochemistry and Cell Biology YouJiang Medical University for NationalitiesBaise CityGuangxi Zhuang Autonomous Region 533000China Shenzhen Institute for Advanced Study University of Electronic Science and Technology of ChinaShenzhen 518110China

Purification of emerging heavy metal antimony contaminated water based on advanced ingenious *** activated modified coconut shell charcoal(CSC)was synthesized and evaluated as a substrate-supported loaded organic photovoltaic material,PM6:PYIT:PM6-b-PYIT,to prepare a surprisingly highly efficient,stable,environmentally friendly,and recyclable organic photocatalyst(CSC–N–P.P.P),which showed excellent effects on the simultaneous removal of Sb(Ⅲ)and Sb(Ⅴ).The removal efficiency of CSC-N-P.P.P on Sb(Ⅲ)and Sb(Ⅴ)reached an amazing 99.9%in quite a short duration of 15 *** the same time,under ppb level and indoor visible light(~1 W m^(2)),it can be treated to meet the drinking water standards set by the European Union and the *** Environmental Protection Agency in 5 min,and even after 25 cycles of recycling,the efficiency is still maintained at about 80%,in addition to the removal of As(Ⅲ),Cd(Ⅱ),Cr(Ⅵ),and Pb(Ⅱ)can also be *** catalyst not only solves the problems of low reuse rate,difficult structure adjustment and high energy consumption of traditional photocatalysts but also has strong applicability and practical *** pioneering approach provides a much-needed solution strategy for removing highly toxic heavy metal antimony pollution from the environment.

关键词： Organic photocatalyst Photocatalysis Purification Indoor visible light

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

shinyTempSignal:an R shiny application for exploring temporal and other phylogenetic signals

引用

Journal of Genetics and Genomics 2024年第7期51卷 762-768页

作者： Li Zhan Xiao Luo Wenqin Xie Xuan-An zhu Zijing Xie Jianfeng Lin Lin Li Wenli Tang Rui Wang Lin Deng Yufan Liao Bingdong Liu Yantong Cai Qianwen Wang Shuangbin Xu Guangchuang Yu Department of Bioinformatics School of Basic Medical SciencesSouthern Medical UniversityGuangzhouGuangdong 510515China Faculty of Computers Guangdong University of TechnologyGuangzhouGuangdong 510006China Ubigene Biosciences Co. Ltd.GuangzhouGuangdong 510530China State Key Laboratory of Applied Microbiology Southern China Guangdong Provincial Key Laboratory of Microbial Culture Collection and ApplicationGuangdong Open Laboratory of Applied MicrobiologyGuangdong Institute of MicrobiologyGuangdong Academy of SciencesGuangzhouGuangdong 510070China

The molecular clock model is fundamental for inferring species divergence times from molecular ***,its direct application may introduce significant biases due to sequencing errors,recombination events,and inaccurately labeled sampling *** accuracy necessitates rigorous quality control measures to identify and remove potentially erroneous ***,while not all branches of a phylogenetic tree may exhibit a clear temporal signal,specific branches may still adhere to the assumptions,with varying evolutionary *** a relaxed molecular clock model better aligns with the complexities of *** root-to-tip regression method has been widely used to analyze the temporal signal in phylogenetic studies and can be generalized for detecting other phylogenetic *** its utility,there remains a lack of corresponding software implementations for broader *** address this gap,we present shinyTempSignal,an interactive web application implemented with the shiny framework,available as an R package and publicly accessible at https://***/YuLab-SMU/*** tool facilitates the analysis of temporal and other phylogenetic signals under both strict and relaxed *** extending the root-to-tip regression method to diverse signals,shinyTempSignal helps in the detection of evolving features or traits,thereby laying the foundation for deeper insights and subsequent analyses.

关键词： Molecular clock Root-to-tip regression Temporal signal Phylogenetic signal

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：