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ZmCER1,a putative ECERIFERUM 1 protein in maize,functions in cuticular wax biosynthesis and bulliform cell development

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The Crop Journal 2024年第3期12卷 743-752页

作者： Yan Zhao Qingzhi Liu xueran Wang weixiao Zhang wei xu Yongzhong Zhang Baoshen Liu College of Agronomy Shandong Agricultural UniversityTai’an 271018ShandongChina Qingdao Academy of Agricultural Sciences Qingdao 266100ShandongChina

The cuticular wax,acting as the ultimate defense barrier,is essential for the normal morphogenesis of plant *** this importance,the connection between wax composition and leaf development has not been thoroughly *** this study,we characterized a new maize mutant,ragged leaf4(rgd4),which exhibits crinkled and ragged leaves starting from the sixth leaf *** phenotype of rgd4 is conferred by ZmCER1,which encoding an aldehyde decarbonylase involved in wax ***1 function deficient mutant displayed reduced cuticular wax density and disordered bulliform cells(BCs),while ZmCER1 overexpressing plants exhibited the opposite effects,indicating that ZmCER1 regulates cuticular wax biosynthesis and BCs ***,as the density of cuticular wax increased,the water loss rate of detached leaf decreases,suggesting that ZmCER1 is positively correlated with plant drought tolerance.

关键词： Ragged leaf ZmCER1 Cuticular wax Bulliform cells

Multistate circularly polarized luminescence switches based on dual stimuli-responsive chiral [2]rotaxanes

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Science China Chemistry 2024年

作者： wei-Tao xu xue Li Xiao-Qin xu xu-Qing Wang Hai-Bo Yang wei Wang Wuhu Hospital East China Normal University (The Second People's Hospital Wuhu) Shanghai Key Laboratory of Green Chemistry and Chemical Processes State Key Laboratory of Petroleum Molecular and Process Engineering School of Chemistry and Molecular Engineering East China Normal University Shanghai Center of Brain-inspired Intelligent Materials and Devices East China Normal University

Aiming at the construction of novel multistate circularly polarized luminescence(CPL) switches, dual stimuli-responsive chiral[2]rotaxanes towards anions and light have been designed and constructed. Through the light-controlled on/off F?rster resonance energy transfer(FRET) switching between the emissive stoppers and anion-induced controllable motions of the chiral wheel for the precise regulations of chirality information transfer from the chiral wheel to the emissive stoppers, precisely switching between four CPL emission states with varied emission wavelengths and dissymmetry factors has been successfully realized,making them a promising platform for practical uses such as information storage and encryption. This proof-of-concept study not only provides a novel design strategy for multistate CPL switching but also contributes excellent candidates for the construction of novel smart chiral luminescent materials.

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Anion-induced differential assembly and structural transformation of supramolecular coordination cages

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Chinese Chemical Letters 2024年第3期35卷 268-272页

作者： Shao-Ping Zheng Yao-wei xu Pei-Yang Su Chen-Hui Liu Yin-Hui Huang Yu-Lin Lu Zhang-Wen wei Zhiwei Jiao Hai-Sen xu Cheng-Yong Su MOE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional MaterialsSchool of ChemistrySun Yat-sen UniversityGuangzhou 510006China Institute of Environmental Research at Greater Bay Area Guangzhou UniversityGuangzhou 510006China State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China

The intimate host-anion interactions will regulate thermodynamics and kinetics in the self-assembly of cationic cages mimicking biological ***,we report construction and transformation of three Pd(Ⅱ)-based metal-organic cages(MOCs)depending on different *** conversions of the lantern-shaped MOC-34 into either octahedral MOC-35 or tricapped trigonal prism MOC-36 are induced by BF_(4)^(–)or NO_(3)^(–),***-36 is kinetically favored and can undergo quantitative conversion to the thermodynamically preferred MOC-35 upon heating,accelerated by excess BF_(4)^(–)to motivate dissociative dynamics of Pd-vertices and lower activation barrier of cage *** guest encapsulation behaviors of MOC-35 and MOC-36 have also been *** results manifest a significance of host-anion dynamics beyond complementary anion template,shedding light on the understanding of intricate anion recognition in nature.

关键词： Supramolecular coordination cage Dynamic host-anion interactions Structural transformation Anion receptor Guest inclusion

Automation in road distress detection,diagnosis and treatment

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Journal of Road Engineering 2024年第1期4卷 1-26页

作者： xu Yang Jianqi Zhang Wenbo Liu Jiayu Jing Hao Zheng wei xu School of Future Transportation Chang'an UniversityXi'an 710064China School of Highway Chang'an UniversityXi'an 710064China School of Information Engineering Chang'an UniversityXi'an 710064China

Road transportation plays a crucial role in society and daily life,as the functioning and durability of roads can significantly impact a nation's economic *** the whole life cycle of the road,the emergence of disease is unavoidable,so it is necessary to adopt relevant technical means to deal with the *** study comprehensively reviews the advancements in computer vision,artificial intelligence,and mobile robotics in the road domain and examines their progress and applications in road detection,diagnosis,and treatment,especially asphalt ***,it analyzes the research progress in detecting and diagnosing surface and internal road distress and related techniques and algorithms are *** addition,also introduces various road gover-nance technologies,including automated repairs,intelligent construction,and path planning for crack *** their proven effectiveness in detecting road distress,analyzing diagnoses,and planning maintenance,these technologies still confront challenges in data collection,parameter optimization,model portability,system accuracy,robustness,and real-time ***,the integration of multidisciplinary technologies is imperative to enable the development of an integrated approach that includes road detection,diagnosis,and *** paper addresses the challenges of precise defect detection,condition assessment,and unmanned *** the same time,the efficiency of labor liberation and road maintenance is achieved,and the automation level of the road engineering industry is improved.

关键词： Road detection Road diagnosis Road treatment Deep learning Intelligent maintenance

Theoretical Exploration of Alloying Effects on Stabilities and Mechanical Properties ofγʹPhase in Novel Co–Al–Nb-Base Superalloys

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Acta Metallurgica Sinica(English Letters) 2024年第7期37卷 1238-1248页

作者： Guan-Cheng Gu Zhao-Jing Han Ze-Yu Chen Zhao-xuan Li Sheng-Bao Xia Zheng-Ning Li Hua Jin wei-wei xu Xing-Jun Liu Shenzhen Research Institute of Xiamen University School of Aerospace EngineeringXiamen UniversityXiamen361005China Institute of Materials Genome and Big Data Harbin Institute of TechnologyShenzhen518055China

The new developedγ/γʹCo–Al–Nb-base alloys show great potentials as high-temperature ***,finding appropriate compositions to improve performance of alloys still poses a great challenge to the development of Co–Al–Nb-base *** by the lack of alloying effects on fundamental properties of criticalγʹphase,we systematically performed a theoretical investigation on the effect of alloying elements TM(TM:Ti,V,Cr,Zr,Mo,Ta,W,Re,and Ru)on phase stabilities and mechanical properties of L1_(2)-typeγʹ(Co,Ni)_(3)(Al,Nb).By analyzing the stability ofγʹphase with respect to its competitive B2 and D0_(19) phases,the results shown that Ti,V,and Cr enhance the L1_(2) stability and widen the L1_(2)–D0_(19) energy barrier,in which V yields the maximum *** analysis of electronic structure indicated that the alternation of valence electrons at fermi level would be the atomic origin for doping TM inγʹ*** calculated results of mechanical properties shown that V and Cr are expected to be optimal dopant for enhancing the strength and the ductility ofγʹ*** addition of Ta is also beneficial for enhancing the strength at the slight expense of ductility ofγʹ*** drawing the mechanical maps,the preferred composition range for the phases with desired properties is roughly demarcated in theory for the multi-addition of V/Cr and V/Ta inγʹ*** findings would be useful for optimizing the performance of novelγ/γʹCo–Al–Nb-base superalloys.

关键词： Co-Al-Nb-base superalloys γ/γʹdual-phase Phase stability Mechanical properties First-principle methods

Genetically modified pigs:Emerging animal models for hereditary hearing loss

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Zoological Research 2024年第2期45卷 284-291页

作者： Xiao Wang Tian-Xia Liu Ying Zhang Liang-wei xu Shuo-Long Yuan A-Long Cui wei-wei Guo Yan-Fang Wang Shi-Ming Yang Jian-Guo Zhao State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Savaid Medical School University of Chinese Academy of SciencesBeijing 100049China Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijing 100101China Beijing Institute for Stem Cell and Regenerative Medicine Beijing 100101China Department of Otolaryngology-Head and Neck Surgery Institute of OtolaryngologyChinese PLA General HospitalBeijing 100853China Division of Life Sciences and Medicine University of Science and Technology of ChinaHefeiAnhui 230022China State Key Laboratory of Animal Biotech Breeding Institute of Animal ScienceChinese Academy of Agricultural SciencesBeijing100193China

Hereditary hearing loss(HHL),a genetic disorder that impairs auditory function,significantly affects quality of life and incurs substantial economic losses for *** investigate the underlying causes of HHL and evaluate therapeutic outcomes,appropriate animal models are *** have been extensively used as valuable large animal models in biomedical *** this review,we highlight the advantages of pig models in terms of ear anatomy,inner ear morphology,and electrophysiological characteristics,as well as recent advancements in the development of distinct genetically modified porcine models of hearing ***,we discuss the prospects,challenges,and recommendations regarding the use pig models in HHL ***,this review provides insights and perspectives for future studies on HHL using porcine models.

关键词： Pigs Animal models Hereditary hearing loss Genetic modification Inner ear

Towards overcoming obstacles of type Ⅱ photodynamic therapy:Endogenous production of light,photosensitizer,and oxygen

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1111-1131页

作者： Lin Yu Zhen Liu wei xu Kai Jin Jinliang Liu Xiaohui Zhu Yong Zhang Yihan Wu Department of Chemical and Environmental Engineering Shanghai UniversityShanghai 200433China School of Medicine Shanghai UniversityShanghai 200433China Department of Biomedical Engineering City University of Hong KongHong KongChina

Conventional photodynamic therapy(PDT)approaches face challenges including limited light penetration,low uptake of photosensitizers by tumors,and lack of oxygen in tumor *** promising solution is to internally generate light,photosensitizers,and *** can be accomplished through endogenous production,such as using bioluminescence as an endogenous light source,synthesizing genetically encodable photosensitizers in situ,and modifying cells genetically to express catalase ***,these strategies have been reinforced by the recent rapid advancements in synthetic *** this review,we summarize and discuss the approaches to overcome PDT obstacles by means of endogenous production of excitation light,photosensitizers,and *** envision that as synthetic biology advances,genetically engineered cells could act as precise and targeted“living factories”to produce PDT components,leading to enhanced performance of PDT.

关键词： Photodynamic therapy Cancer Biogenesis Biosynthesis Engineered bacteria Phototherapy Photosensitizers Catalase

Analysis of pseudo-random number generators in QMC-SSE method

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Chinese Physics B 2024年第3期33卷 75-79页

作者：刘东旭徐维张学锋 Department of Physics Chongqing UniversityChongqing 401331China

In the quantum Monte Carlo(QMC)method,the pseudo-random number generator(PRNG)plays a crucial role in determining the computation ***,the hidden structure of the PRNG may lead to serious issues such as the breakdown of the Markov ***,we systematically analyze the performance of different PRNGs on the widely used QMC method known as the stochastic series expansion(SSE)*** quantitatively compare them,we introduce a quantity called QMC efficiency that can effectively reflect the efficiency of the *** testing several representative observables of the Heisenberg model in one and two dimensions,we recommend the linear congruential generator as the best choice of *** work not only helps improve the performance of the SSE method but also sheds light on the other Markov-chain-based numerical algorithms.

关键词： stochastic series expansion quantum Monte Carlo pseudo-random number generator

{1012}twin–twin intersection-induced lattice rotation and dynamic recrystallization in Mg–6Al–3Sn–2Zn alloy

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Journal of Magnesium and Alloys 2024年第4期12卷 1529-1539页

作者： Bin-Jiang Lv Sen Wang Fu-Hao Gao Ning Cui Yi-Nan Li Tie-wei xu Feng Guo School of Mechanical and Automotive Engineering Qingdao University of Technology266520China Key Lab of industrial Fluid Energy Conservation and Pollution Control Qingdao University of Technology266520China

This study investigated the formation mechanism of new grains due to twin–twin intersections in a coarse-grained Mg–6Al–3Sn–2Zn alloy during different strain rates of an isothermal *** results of electron backscattered diffraction investigations showed that the activated twins were primarily{1012}tension twins,and 60°boundaries formed due to twin–twin intersections under different strain *** twin variants with 60°boundaries transformed into new grains through lattice rotations at a low strain rate(0.01 s^(−1)).At a high strain rate(10 s^(−1)),the regions surrounded by subgrain boundaries through high-density dislocation arrangement and the 60°boundaries transformed into new grains via dynamic recrystallization.

关键词： Mg alloy Twin-twin intersection Lattice rotation Dynamic recrystallization