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体外膜肺氧合支持下经皮冠状动脉介入治疗患者预后的影响因素

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实用医学杂志 2024年第2期40卷 219-224页

作者：赵倩张艳乔荞邓爱云兰州大学第一临床医学院兰州730000 兰州大学第一医院心内超声室兰州730000

目的探讨动静脉体外膜肺氧合(VA-ECMO)支持下经皮冠状动脉介入(PCI)治疗急性心肌缺血合并难治性心源性休克患者预后的影响因素。方法回顾性分析2022年1月至2023年4月期间于兰州大学第一医院因急性心肌缺血合并难治性心源性休克接受VA-E... 详细信息

目的探讨动静脉体外膜肺氧合(VA-ECMO)支持下经皮冠状动脉介入(PCI)治疗急性心肌缺血合并难治性心源性休克患者预后的影响因素。方法回顾性分析2022年1月至2023年4月期间于兰州大学第一医院因急性心肌缺血合并难治性心源性休克接受VA-ECMO辅助行PCI治疗70例患者的临床资料,根据VA-ECMO撤机成功与否将其分为成功组(54例)和失败组(16例),比较两组患者一般资料、术中情况、血流动力学及生化指标结果,分析影响患者临床结局的独立风险因素。结果成功组ECMO辅助时间明显小于失败组(P0.05)。两组患者术前TIMI分级、病变血管支数、IVUS使用情况、心电图结果、SYNTAX评分等差异均无统计学意义(P>0.05)。与治疗前相比,ECMO辅助PCI治疗后患者的动脉血氧饱和度(SaO2)、左室每搏量(LVSV)、左室射血分数(LVEF)、二尖瓣侧壁瓣环收缩速度(Sa)、主动脉瓣口前向血流频谱(AV)、速度-时间积分(VTI)、三尖瓣瓣环收缩期位移(TAPSE)明显升高(P0.05)。单因素logistic回归分析结果显示ECMO辅助时间、HR、Lac、CRP、AST及TBIL是影响急性心肌缺血合并难治性心源性休克患者撤机失败的因素。结论VA-ECMO辅助PCI治疗可显著改善急性心肌缺血合并难治性心源性休克患者心脏功能,超声心动图参数(LVESV、LVSV、LVEF、Sa、AV、VTI、TAPSE)及临床指标(HR、Lac、CRP、AST、TBIL)动态评估对患者预后具有一定的临床价值。

关键词：体外膜肺氧合经皮冠状动脉介入超声心动图动静脉体外膜肺氧合

高温作用后砂岩的孔隙分形特征与岩石本构模型研究

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华中科技大学学报（自然科学版） 2024年第2期52卷 142-148页

作者：郝家旺李庆文乔兰邓乃夫北京科技大学城市地下空间工程北京市重点实验室北京100083 石家庄铁道大学安全工程与应急管理学院河北石家庄050043

基于砂岩的核磁共振与力学试验,结合孔隙结构分形理论,分析了高温对砂岩力学性能的双重影响,研究了孔隙分形维数与力学参数的内在机制.结果表明:在150~300℃范围内,力学性能被显著强化;当温度超过450℃后,力学性能将会被显著弱化.砂岩... 详细信息

基于砂岩的核磁共振与力学试验,结合孔隙结构分形理论,分析了高温对砂岩力学性能的双重影响,研究了孔隙分形维数与力学参数的内在机制.结果表明:在150~300℃范围内,力学性能被显著强化;当温度超过450℃后,力学性能将会被显著弱化.砂岩内部的中孔与大孔具有显著的分形特征,其分形维数与力学参数呈负相关,微孔不具有分形特征.构建了峰后应力跌落的分段式本构模型,提出了峰后应变软化因子n的概念.研究表明,该模型能够合理反映高温作用后多孔砂岩应力应变曲线的变化特征.

关键词：高温岩石力学核磁共振孔隙结构分形维数本构模型

The relationship between the distribution of HBcAg in liver cells and the pathological manifestations of the liver in 429 HBeAg-positive chronic HBV-infected individuals

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Gastroenterology & Hepatology Research 2024年第3期6卷 10-15页

作者： Fan Nie Chang-Chun Zeng Guang-Dong Tong Mu-Min Shao Xiao-Hua Le Xin deng Da-qiao Zhou National Clinical Research Center for Infectious Diseases Shenzhen 518112China Central Laboratory of Shenzhen Longhua District Central Hospital Shenzhen 518112China Hepatology Department of Shenzhen Traditional Chinese Medicine Hospital Shenzhen 518112China Pathology Department of Shenzhen Traditional Chinese Medicine Hospital Shenzhen 518112China Pathology Department of Shenzhen Third People's Hospital Shenzhen 518112China Traditional Chinese Medicine Department of Shenzhen Third People's Hospital Shenzhen 518112China

Background:The natural history of chronic HBV infection is typically characterized by four stages:the immune tolerance period,the immune clearance period,the immune control period,and the immune escape *** stages are associated with the distribution of HBcAg in liver cells;however,this relationship remains a topic of broad debate within the field of liver *** objectively and quantitatively measure the intracellular distribution of HBcAg,this paper aims to design a method referred to as the“layered evaluation method”and to examine its ***:The distribution of HBcAg in liver cells is assessed using Image Pro Plus image processing software,along with calculations of cytoplasmic and nuclear positive staining ***:The findings indicate that the highest proportion of patients exhibited a positive cytoplasmic expression rate ranging from 0-2.5%.More than 40% of the total sample was categorized within the 0-2.5% positive nuclear expression *** HBcAg cytoplasmic positive staining rates were classified into five levels:a cytoplasmic HBcAg positive staining rate of less than 0.05% is designated as level 0,indicating negative expression;a staining rate between 0.05% and 5% is classified as level 1;a rate from 5% to less than 10% is classified as level 2;a rate from 10% to less than 20% is classified as level 3;and a nuclear positivity rate exceeding 20% is classified as level ***:The inflammatory activity grade in these patients was positively correlated with the cytoplasmic distribution of ***,the nuclear distribution rate of HBcAg was significantly higher in the G3 group compared to the other groups.

关键词： distribution of HBcAg pathological manifestations of the liver positive staining rate

Analysis of sleep quality,disease uncertainty,and psychological tolerance in patients undergoing chemotherapy for digestive tract malignancies

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World Journal of Clinical Cases 2024年第20期12卷 4247-4264页

作者： Wen-Wen Tang Mei-Lin Han Shu-Hua Xu You-Xing deng qiao Shen Qian-Wen Ma Jie Wen Department of Oncology Hefei BOE HospitalHefei 230011Anhui ProvinceChina Department of Nursing Hefei BOE HospitalHefei 230011Anhui ProvinceChina Department of Emergency Jingxian HospitalXuancheng 242000Anhui ProvinceChina 不详

BACKGROUND Colorectal cancer is the second leading cause of cancer-related deaths among digestive tract malignancies,following gastric *** is of great significance for maintaining human *** incidence of sleep disorders in patients with cancer is approximately twice that observed in the general *** of sleep can prolong hospital stays,increase the likelihood of infection,and increase mortality ***,studying the factors related to sleep quality is significant for improving the quality of life of patients with malignant tumors of the digestive *** To investigate the relationships among sleep quality,disease uncertainty,and psychological resilience in patients undergoing chemotherapy for digestive tract *** A total of 131 patients with malignant digestive tract tumors who were treated at Hefei BOE Hospital between April 2021 and September 2022 were selected as research *** on their Pittsburgh Sleep Quality Index(PSQI)scores,participants were divided into either the sleep disorder group(PSQI score>7)or the normal sleep group(PSQI score≤7).The clinical data—together with the Mishel Uncertainty in Illness Scale for Adults(MUIS-A)and Connor-Davidson Resilience Scale(CD-RISC)scores—were *** In this study,78(59.54%)patients with digestive tract malignancies developed sleep disorders after *** disorder incidence was higher in patients with colorectal cancer than in those with gastric and esophageal cancers(P<0.05).The total MUIS-A score and those for each item in the sleep disorder group were higher than those in the normal sleep *** total CD-RISC score and those for each item in the sleep disorder group were lower than those in the normal sleep group(P<0.05).The PSQI scores of patients with malignant digestive tract tumors were positively correlated with the scores for lack of disease information,disease uncertainty,and unpredictability in the MUIS-A and negatively co

关键词： Malignant digestive tract tumor Chemotherapy Sleep quality Disease uncertainty Psychological resilience

Effects of anterior sciatic nerve acupuncture on lower limb paralysis after cerebral infarction:study protocol for a randomized controlled trial

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Journal of Traditional Chinese Medicine 2024年第1期44卷 205-211页

作者： LI Menghan WANG Yu RAN Dawei YANG Xinming deng Shizhe SHI Lei MENG Zhihong Department of Acupuncture First Teaching Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300193China National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion Tianjin 300193China Graduate department Tianjin University of Traditional Chinese MedicineTianjin 301617China Department of Massage and Rehabilitation Second Affiliated Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300250China

Stroke is the main cause of disability in the middle and old ***,especially lower limb paralysis,often leads to the loss of self-care ability and a series of secondary *** main method to improve hemiplegic limb movement is exercise therapy,but there are still many patients with disabilities after rehabilitation *** one of the non-pharmacological therapies for stroke,acupuncture has been recognized to improve motor function in ***,we propose a new method,anterior sciatic nerve acupuncture,which can stimulate both the femoral nerve and the sciatic *** designed this study to determine the effect of this method on lower limb motor *** participants recruited with hemiplegia after cerebral infarction will be randomly assigned to the test group or control group in a 1:1 *** control group will receive Xingnao Kaiqiao acupuncture,and the test group will receive anterior sciatic nerve acupuncture on this *** participants will get acupuncture treatment once a day,6 times a week for 2 *** primary outcome is Fugl-Meyer Assessment of Lower Extremity and the secondary outcomes are Modified Ashworth Scale and Modified Barthel *** will be collected before treatment,1week after treatment,and 2 weeks after treatment,and then statistical analysis will be *** study can preliminarily verify the effect of anterior sciatic nerve acupuncture on improving lower limb motor function in patients with cerebral infarction,which may provide an alternative approach for clinical treatment of hemiplegia.

关键词： anterior sciatic nerve acupuncture paralysis cerebral infarction Xingnao Kaiqiao clinical protocols

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基于形式化方法的区块链系统漏洞检测模型

软件学报 2024年第9期35卷 4193-4217页

作者：陈锦富冯乔伟蔡赛华施登洲 Rexford Nii Ayitey SOSU 江苏大学计算机科学与通信工程学院江苏镇江212013 江苏省工业网络安全技术重点实验室(江苏大学) 江苏镇江212013 Faculty of Computing and Information Systems Ghana Communication Technology UniversityAccra 23321Ghana

随着区块链技术在各行各业的广泛应用,区块链系统的架构变得越来越复杂,这也增加了安全问题的数量.目前,在区块链系统中采用了模糊测试、符号执行等传统的漏洞检测方法,但这些技术无法有效检测出未知的漏洞.为了提高区块链系统的安全性... 详细信息

随着区块链技术在各行各业的广泛应用,区块链系统的架构变得越来越复杂,这也增加了安全问题的数量.目前,在区块链系统中采用了模糊测试、符号执行等传统的漏洞检测方法,但这些技术无法有效检测出未知的漏洞.为了提高区块链系统的安全性,提出基于形式化方法的区块链系统漏洞检测模型VDMBS(vulnerability detection model for blockchain systems),所提模型综合系统迁移状态、安全规约和节点间信任关系等多种安全因素,同时提供基于业务流程执行语言BPEL(business process execution language)的漏洞模型构建方法.最后,用NuSMV在基于区块链的电子投票选举系统上验证所提出的漏洞检测模型的有效性,实验结果表明,与现有的5种形式化测试工具相比,所提出的VDMBS模型能够检测出更多的区块链系统业务逻辑漏洞和智能合约漏洞.

关键词：区块链系统安全因素漏洞检测模型形式化验证 BPEL流程

The energy response of LaBr_(3)(Ce),LaBr_(3)(Ce,Sr),and NaI(Tl)crystals for GECAM

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Nuclear Science and Techniques 2024年第2期35卷 110-122页

作者： Pei-Yi Feng Xi-Lei Sun Zheng-Hua An Yong deng Cheng-Er Wang Huang Jiang Jun-Jie Li Da-Li Zhang Xin-qiao Li Shao-Lin Xiong Chao Zheng Ke Gong Sheng Yang Xiao-Jing Liu Min Gao Xiang-Yang Wen Ya-Qing liu Yan-Bing Xu Xiao-Yun Zhao Jia-Cong Liu Fan Zhang Hong Lu Particle and Astrophysics Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Experimental Physics Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China School of Nuclear Science and Technology University of South ChinaHengyang 421001China National Engineering Research Center for Rare Earth Grirem Advanced Materials Co.Ltd.and General Research Institute for Nonferrous MetalsBeijing 100088China

The GECAM series of satellites utilizes LaBr_(3)(Ce),LaBr_(3)(Ce,Sr),and NaI(Tl)crystals as sensitive materials for gamma-ray detectors(GRDs).To investigate the nonlinearity in the detection of low-energy gamma rays and address the errors in the calibration of the E-C relationship,comprehensive tests and comparative studies of the three aforementioned crystals were conducted using Compton electrons,radioactive sources,and mono-energetic *** nonlinearity test results of the Compton electrons and X-rays demonstrated substantial differences,with all three crystals presenting a higher nonlinearity for X/-rays than for Compton *** the LaBr_(3)(Ce)and LaBr_(3)(Ce,Sr)crystals having higher absolute light yields,they exhibited a noticeable nonlinear decrease in the light yield,especially at energies below 400 *** NaI(Tl)crystal demonstrated an"excess"light output in the 6-200 keV range,reaching a maximum"excess"of 9.2%at 30 keV in the X-ray testing and up to 15.5%at 14 keV during Compton electron testing,indicating a significant advantage in the detection of low-energy gamma ***,we explored the underlying causes of the observed nonlinearity in these *** study not only elucidates the detector responses of GECAM,but also initiates a comprehensive investigation of the nonlinearity of domestically produced lanthanum bromide and sodium iodide crystals.

关键词： LaBr_(3)(Ce)detector LaBr_(3)(Ce,Sr)detector NaI(Tl)detector GECAM Energy response Light yield nonlinearity

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基于船舶横向进坞的新型浮船坞设计

造船技术 2024年第4期52卷 1-6,47页

作者：邓艳新乔勇卫雪丽中国船舶集团青岛北海造船有限公司船舶与海洋工程设计研究所山东青岛266520

常规浮船坞一般为固定坞墙设计型式,在码头以沉浮方式实现船舶进坞。针对该现状,设计一种基于船舶横向进坞的新型浮船坞。提出新型浮船坞整体设计方案、活动坞墙设计方案和浮箱甲板轨道、轨道连接梁与刚性系泊装置的设计方案。经实际操... 详细信息

常规浮船坞一般为固定坞墙设计型式,在码头以沉浮方式实现船舶进坞。针对该现状,设计一种基于船舶横向进坞的新型浮船坞。提出新型浮船坞整体设计方案、活动坞墙设计方案和浮箱甲板轨道、轨道连接梁与刚性系泊装置的设计方案。经实际操作验证,新型浮船坞设计有效可行,可为后续国内浮船坞设计提供参考,为浮船坞的船舶进坞方式设计开阔思路。

关键词：浮船坞横向进坞活动坞墙浮箱甲板轨道轨道连接梁刚性系泊装置

不同熔盐体系制备CeO_(2)及光催化性能研究

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稀土 2024年第4期45卷 53-63页

作者：王伟储智尧王远田维浩张登卫张桥浪兰苑培贵州大学材料与冶金学院贵州贵阳550025 贵州省冶金工程与过程节能重点实验室贵州贵阳550025

研究了K_(2)CO_(3)/Li_(2)CO_(3)、LiCl/KCl、CaCl_(2)/NaCl、CaCl_(2)/KCl及NaCl/KCl五种熔盐体系熔盐法制备CeO_(2)的光催化性能。结果表明,各熔盐体系制备的CeO_(2)光催化性能遵循K_(2)CO_(3)/Li_(2)CO_(3)>LiCl/KCl>CaCl_(2)/NaCl>CaCl_(2)/KCl>NaCl/KCl,其中最优光催化性能达到光照120 min对亚甲基蓝(MB)的降解率为95.91%。以该熔盐体系制备的CeO_(2)为研究对象,考察了溶液pH=4~10及反应温度为25℃~65℃对CeO_(2)光催化降解亚甲基蓝性能的影响,发现随反应温度升高CeO_(2)的光催化性能先升后降,当反应温度为45℃时,反应120 min后MB降解率达99.90%;溶液pH升高,MB的降解率呈上升趋势,当pH=10时反应120 min后MB降解率为99.36%;结合最优反应温度及反应pH,CeO_(2)对MB的降解效率得到进一步提升,光照条件下反应120 min对MB的降解为99.99%,速率常数k=0.03964 min^(-1)。

关键词：熔盐法 CeO_(2) 光催化温度 pH