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An integrated approach for machine-learning-based system identification of dynamical systems under control:application towards the model predictive control of a highly nonlinear reactor system

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Frontiers of Chemical Science and Engineering 2022年第2期16卷 237-250页

作者： Ewan Chee wee chin wong Xiaonan Wang Department of Chemical&Biomolecular Engineering Faculty of EngineeringNational University of SingaporeSingapore 117585Singapore Chemical Engineering&Food Technology Cluster Singapore Institute of TechnologySingapore 138683Singapore

Advanced model-based control strategies,e.g.,model predictive control,can offer superior control of key process variables for multiple-input multiple-output *** quality of the system model is critical to controller performance and should adequately describe the process dynamics across its operating range while remaining amenable to fast *** work articulates an integrated system identification procedure for deriving black-box nonlinear continuous-time multiple-input multiple-output system models for nonlinear model predictive *** showcase this approach,five candidate models for polynomial and interaction features of both output and manipulated variables were trained on simulated data and integrated into a nonlinear model predictive controller for a highly nonlinear continuous stirred tank reactor *** procedure successfully identified system models that enabled effective control in both servo and regulator problems across wider operating *** controllers also had reasonable per-iteration times of ca.0.1 *** demonstration of how such system models could be identified for nonlinear model predictive control without prior knowledge of system dynamics opens further possibilities for direct data-driven methodologies for model-based control which,in the face of process uncertainties or modelling limitations,allow rapid and stable control over wider operating ranges.

关键词： nonlinear model predictive control black-box modeling continuous-time system identification machine learning industrial applications of process control

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Renminbi Appreciation and china's Industrial Upgrading

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china & World Economy 2022年第3期30卷 1-22页

作者： chin-Yoong wong Yoke-Kee Eng Department of Economics Faculty of Business&FinanceUniversiti Tunku Abdul RahmanMalaysia Faculty of Business&Finance Universiti Tunku Abdul RahmanMalaysia

To identify the macroeconomic environment that has enabled china's industrial upgrading during a period of persistent renminbi appreciation,we construct a two-country New Keynesian model of industrial upgrading with a global production network,endogenous firm entry,and a directed quality *** show that renminbi appreciation promotes industrial upgrading without hurting real economic growth in the longer *** holds true especially through four ***,the quality threshold for firm entry is lower to allow for more firms participation and thus greater product varieties(quality threshold channel).Second,upstream skill-based production uses more imported inputs of higher quality(imported input channel).Third,there is substantial global demand towards the exports of high-quality inputs(global demand channel).Fourth,domestic inputs are competing against imported inputs to broaden the scope for competition in the upstream product market to incentivize quality upgrading(scope for competition channel).

关键词： endogenous firm entry global production sharing industrial upgrading renminbi appreciation structural reform

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Van der Waals magnets: Wonder building blocks for two-dimensional spintronics?

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InfoMat 2019年第4期1卷 479-495页

作者： Wen Zhang Ping Kwan Johnny wong Rui Zhu Andrew T.S.wee Department of Physics National University of SingaporeSingaporeSingapore Centre for Advanced 2D Materials(CA2DM)and Graphene Research Centre(GRC) National University of SingaporeSingaporeSingapore

The unprecedented realization of two-dimensional(2D)van der Waals magnets excitingly extends the synergy between spintronics and 2D materials,started with graphene over the last *** article reviews the recent milestones in the development of 2D magnets and its derived *** particular,a number of critical challenges centered around the scalability,ambient stability and Curie temperature of these atomically thin magnets are *** mini-review also provides an outlook on what the future might hold for this integrated field of 2D spintronics,and assesses its potential in postsilicon electronics.

关键词： spintronics transition-metal chalcogenide two-dimensional material van der Waals magnets

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Management of cytomegalovirus corneal endotheliitis

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Eye and Vision 2021年第1期8卷 18-30页

作者： Angela H.Y.wong wee Nie Kua Alvin L.Young Kelvin H.Wan Department of Ophthalmology Tuen Mun HospitalHong KongChina Department of Ophthalmology and Visual Sciences Prince of Wales HospitalHong KongChina Department of Ophthalmology and Visual Sciences The Chinese University of Hong KongHong KongChina

Background:Cytomegalovirus(CMV)can manifest as corneal endotheliitis in immunocompetent *** diagnosis is prudent to prevent endothelial cell loss,which could ultimately lead to corneal *** DNA was first detected in an eye with corneal endotheliitis in 2006;since then,clinical evidence from numerous case reports and case series have *** text:In this narrative review,we identified several drugs,including ganciclovir,valganciclovir,and their combination in oral,intravenous,intravitreal,and topical forms in different concentrations,together with the judicious use of topical steroids,have reported variable *** has yet to be any prospective comparative study evaluating the efficacy and safety of these assorted forms of treatment;clinical evidence is based on case reports and case *** endotheliitis presenting with corneal edema can masquerade as other corneal diseases and thus poses a great challenge especially in post-keratoplasty *** awareness is needed before and after keratoplasty to start prompt prophylaxis and ***:There is no consensus on the management of CMV *** studies are much needed to elucidate the optimal treatment modality,regime,and duration in the treatment and prophylaxis of CMV endotheliitis.

关键词： Cytomegalovirus CMV Endotheliitis Keratoplasty Corneal transplant Cornea

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Cloning of a novel phytase from an anaerobic rumen bacterium, Mitsuokella jalaludinii, and its expression in Escherichia coli

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Journal of Integrative Agriculture 2015年第9期14卷 1816-1826页

作者： TAN Wan-qin Phang Chiun Yee Sieo chin chin Yiap Beow chin Clemente Michael wong Vui Ling Norhani Abdullah Son Radu Ho Yin Wan Laboratory of Vaccines and Immunotherapeutics Institute of BioscienceUniversiti Putra Malaysia Department of Microbiology Faculty of Biotechnology and Biomolecular SciencesUniversiti Putra Malaysia Department of Life Sciences School of Pharmacy and HealthFaculty of Medicine and HealthInternational Medical University Biotechnology Research Institute Universiti Malaysia Sabah Institute of Tropical Agriculture Universiti Putra Malaysia Department of Biochemistry Faculty of Biotechnology and Biomolecular SciencesUniversiti Putra Malaysia Department of Food Science Faculty of Food Science and TechnologyUniversiti Putra Malaysia

The ful length phytase gene of Mitsuokel a jalaludini was successful y cloned and was found to be 1 047 bp in length, with 348 amino acids, and was designated as PHY7 phytase gene. A comparison of the sequence of PHY7 phytase gene of M. jalaludini with various microbial phytase gene sequences showed that it was not similar to those from other bacteria except Selenomonas ruminatium, thus suggesting that they may both express a new class of phytase. The PHY7 phytase gene was subsequently subcloned into bacterial expression vector, pET32a, for expression in Escherichia coli strain Ro-setta-gami. Expression of the recombinant phytase gene was optimised and characterised. The recombinant phytase was estimated to be approximately 55 kDa by SDS-PAGE analysis. The recombinant phytase exhibited optimum activity at 55°C, pH 4.5 and showed good pH stability from pH 3.5 to 5.5 (>78%relative activity). Metal ions such as Ca2+, Mg2+, and K+were found to exert signiifcant stimulatory effect on the recombinant phytase activity while Cu2+, Fe3+, and Zn2+greatly inhibited the enzyme activity. The recombinant phytase showed moderate resistance to trypsin proteolysis, but susceptible to pepsin proteolysis. The results of the study showed that several characteristics of recombinant phytase were slightly different from the native enzyme. Unfavourable characteristics such as reduced pH stability and metal ion effects should be taken into consideration during feed enzyme formulation.

关键词： phytase cloning recombinant Escherichia coli Mitsuokella jalaludinii

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Temperature Measurement of Small Objects by Mach-Zehnder Interferometer

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Journal of Thermal Science 1993年第4期2卷 270-274页

作者： Y.T.wong W.K.chin Hong Kong Polytechnic

A Mach-Zehnder Interferometer incorporated with image processing has been set up to study the temperature field of small *** objects with width to height ratios ranging from 0.33 to 1.0 subjected to natural convection are used to simulate the condition at which the end effects are significant. Interferogram representing the temperature gradient is captured,digitized,and image processed with the aid of an image processing unit.A simple correction model is proposed to treat the stored interferometric *** interference data are found to compare well with those provided by the thermocouples.

关键词： temperature measurement small objects mach-zehnder interferometer

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Concomitant atopic dermatitis and narcolepsy type 1:psychiatric implications and challenges in management

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General Psychiatry 2019年第5期32卷 279-282页

作者： Justin chin Craig Bearison Nanette Silverberg Mary Lee wong Department of Primary Care Touro College of Osteopathic MedicineNew York CityNew YorkUSA Department of Internal Medicine Beth Israel Medical CenterNew York CityNew YorkUSA Department of Pediatric Dermatology Mount Sinai Health SystemNew York CityNew YorkUSA Department of Allergy and Immunology Beth Israel Medical CenterNew York CityNew YorkUSA Department of Medicine Icahn School of Medicine at Mount SinaiNew York CityNew YorkUSA

Atopic dermatitis(AD)and narcolepsy type 1(NT1)are two distinct diseases that have not been classically shown to be *** potential connection between the known immunological aetiology of AD and the proposed autoimmune pathophysiology of dysregulation in NT1;however,is the subject of ongoing speculation and debate with advances in gene sequencing and ***,we present a case of a patient with concomitant refractory AD and NT1 and review the current research on their immunological relationship and the challenges in management relative to disease burden and psychiatric comorbidities.

关键词： dermatitis psychiatric diseases

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A low power 50Hz argon plasma for surface modification of polytetrafluoroethylene

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Plasma Science and Technology 2022年第11期24卷 1-13页

作者： Yen Theng LAU wee Siong CHIU Hong Chun LEE Haw Jiunn WOO Oi Hoong chin Teck Yong TOU Department of Physics Faculty of ScienceUniversity of MalayaKuala Lumpur 50603Malaysia Faculty of Engineering Multimedia UniversityPersiaran CyberjayaCyberjaya 63100Malaysia

The characteristics of a low power 50 Hz argon plasma for surface treatment of polytetrafluoroethylene(PTFE)film is presented in this *** current–voltage behavior of the discharge and time-varying intensity of the discharge showed that a DC glow discharge was generated in reversed polarity at every *** discharge power between 0.5 and 1 W,the measured electron temperature and density were 2–3 eV and∼10^(8) cm^(−3),*** optical emission spectrum of the argon plasma showed presence of some‘impurity species’such as OH,N_(2) and H,which presumably originated from the residual air in the discharge *** exposure of PTFE films to the argon glow plasma at pressure 120 Pa and discharge power 0.5 to 1 W,the water contact angle reduced by 4%to 20%from the original 114°at pristine condition,which confirms improvement of its surface *** increase in wettability was attributed to incorporation of oxygen-containing functional groups on the treated surface and concomitant reduction in fluorine as revealed by the XPS analysis and increase in surface roughness analyzed from the atomic force *** upon storage in ambient air showed retention of the induced increase in surface wettability.

关键词： 50 Hz glow discharge plasma surface treatment PTFE hydrophobic recovery ageing effect

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A review on co-pyrolysis of agriculture biomass and disposable medical face mask waste for green fuel production:recent advances and thermo-kinetic models

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Frontiers of Chemical Science and Engineering 2023年第9期17卷 1141-1161页

作者： Melvin X.J.wee Bridgid L.F.chin Agus Saptoro Chung L.Yiin Jiuan J.Chew Jaka Sunarso Suzana Yusup Abhishek Sharma Department of Chemical and Energy Engineering Faculty of Engineering and ScienceCurtin University MalaysiaCDT 250Miri 98009Malaysia Energy and Environment Research Cluster Faculty of Engineering and ScienceCurtin University MalaysiaCDT 250Miri 98009Malaysia Department of Chemical Engineering and Energy Sustainability Faculty of EngineeringUniversiti Malaysia Sarawak(UNIMAS)Kota Samarahan 94300Malaysia Institute of Sustainable and Renewable Energy(ISuRE) Universiti Malaysia Sarawak(UNIMAS)Kota Samarahan 94300Malaysia Research Centre for Sustainable Technologies Faculty of EngineeringComputing and ScienceSwinburne University of TechnologyKuching 93350Malaysia Generation Unit(Fuel Technology&Combustion) Tenaga Nasional Berhad(TNB)Research Sdn BhdKajang 43000Malaysia Department of Chemical Engineering Manipal University JaipurJaipur 303007India Chemical&Environmental Engineering School of EngineeringRMIT UniversityMelbourneVictoria 3000Australia

The Association of Southeast Asian Nations is blessed with agricultural resources,and with the growing population,it will continue to prosper,which follows the abundance of agricultural *** biomass attracted researchers’interest in extracting bio-oil from these ***,the resulting bio-oil has low heating values and undesirable physical ***,co-pyrolysis with plastic or polymer wastes is adopted to improve the yield and quality of the ***,with the spread of the novel coronavirus,the surge of single-use plastic waste such as disposable medical face mask,can potentially set back the previous plastic waste reduction ***,studies of existing technologies and techniques are referred in exploring the potential of disposable medical face mask waste as a candidate for co-pyrolysis with *** parameters,utilisation of catalysts and technologies are key factors in improving and optimising the process to achieve commercial standard of liquid *** copyrolysis involves a series of complex mechanisms,which cannot be explained using simple iso-conversional ***,advanced conversional models are introduced,followed by the evolutionary models and predictive models,which can solve the non-linear catalytic copyrolysis reaction *** outlook and challenges for the topic are discussed in detail.

关键词： biomass COVID-19 wast catalyst pyrolysis kinetics

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VR and AR in human performance research―An NUS experience

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Virtual Reality & Intelligent Hardware 2020年第5期2卷 381-393页

作者： Jun-Hao YIN chin-Boon CHNG Pooi-Mun wong Nicholas HO Matthew CHUA Chee-Kong CHUI Department of Mechanical Engineering National University of Singapore119077Singapore Institute of Systems Science National University of Singapore119077Singapore

With the mindset of constant improvement in efficiency and safety in the workspace and training in Singapore,there is a need to explore varying technologies and their capabilities to fulfil this *** ability of Virtual Reality(VR)and Augmented Reality(AR)to create an immersive experience of tying the virtual and physical environments coupled with information filtering capabilities brings a possibility of introducing this technology into the training process and *** paper surveys current research trends,findings and limitation of VR and AR in its effect on human performance,specifically in Singapore,and our experience in the National University of Singapore(NUS).

关键词： Human computer interaction Virtual environment Human performance

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