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Atorvastatin-induced severe gastric ulceration: A case report

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World Journal of Gastroenterology 2005年第20期11卷 3159-3160页

作者： Ihab I el-hajj Fadi H Mourad Nina S Shabb Kassem A Barada Department of Internal Medicine American University of Beirut Medical Center(AUBMC) Beirut Lebanon Department of Pathology AUBMC Beirut Lebanon

A 41-year-old man presented with severe gastric ulceration 3 mo after beginning treatment with atorvastatin 20 mg once daily for hypercholesterolemia. The patient was not taking any ulcerogenic drugs and had no evidence of Helicobacter pylori infection. Proton pump inhibitor therapy was initiated and atorvastatin was replaced by simvastatin with complete resolution of gastrointestinal symptoms. To our knowledge, this is the first report of atorvastatin-induced gastric ulceration,which should be looked for in patients who develop abdominal pain while on this drug.

关键词： Atorvastatin Drug toxicity Gastric ulceration

Giant sporadic fundic gland polyp:Endoscopic and endosonographic features and management

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World Journal of Gastroenterology 2008年第42期14卷 6593-6595页

作者： Ihab I el hajj Mohamad Hawchar Assaad Soweid Karim Maasri Ayman Tawil Kassem A Barada Department of Internal Medicine Division of Gastroenterology and Hepatology American University of Beirut Medical Center PO Box 11-0236 Beirut 11072020 Lebanon Department of Pathology and Laboratory Medicine American University of Beirut Medical Center Beirut 11072020 Lebanon

Fundic gland polyps are the most common gastric polyps. They are usually small in size, sporadic and asymptomatic. We present a case of giant fundic gland polyp. Our case is particular because of the clinical presenta... 详细信息

关键词： Fundic gland polyp Anemia Endoscopic ultrasonography

Endoscopically managed sunflower bezoar

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Laparoscopic, Endoscopic and Robotic Surgery 2020年第2期3卷 48-51页

作者： Samih Hwalla elias Saikaly Melissa Kyriakos Saad Ihab el hajj Saint George Hospital University Medical Center BeirutLebanon

Rectal bezoar is *** is important to admit the patient with huge colorectal phytobezoars to hospital for monitoring,especially if patient needs several endoscopic trials for *** presented a case of 14-year-old male patient with phytobezoars of sunflower seed extending from the recto sigmoid junction till the *** patient was successfully managed with endoscopic evacuation.

关键词： Bezoar Endoscopic disimpaction Colorectal surgery

Celecoxib-induced cholestatic liver failure requiring orthotopic liver transplantation

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World Journal of Gastroenterology 2009年第31期15卷 3937-3939页

作者： Ihab I el hajj Shahid M Malik Hany R Alwakeel Obaid S Shaikh Eizaburo Sasatomi Hossam M Kandil Department of Internal Medicine Division of GastroenterologyHepatology and NutritionUniversity of Pittsburgh Medical Center Department of Pathology University of Pittsburgh

Selective cyclooxygenase-2 （COX-2） inhibitors are widely used due to their efficacy and good safety profile. However, recent case reports have described varying degrees of liver injudes associated with the use of COX-2 inhibitors. We report the case of a patient who developed acute cholestatic hepatitis progressing to hepatic failure requiring liver transplantation, following a 3-d course of celecoxib for treatment of generalized muscle aches and pains. The clinical presentation, the laboratory data, as well as the liver histopathology were supportive of the putative diagnosis of drug induced liver injury.

关键词： Celecoxib Cholestatic hepatitis Liver failure Liver transplantation

A randomized controlled trial of imipramine in patients with irritable bowel syndrome

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World Journal of Gastroenterology 2009年第29期15卷 3636-3642页

作者： Heitham Abdul-Baki Ihab I el hajj Lara elZahabi Cecilio Azar elie Aoun Assaad Skoury Hani Chaar Ala I Sharara Department of Internal Medicine Division of Gastroenterology American University of Beirut Medical Center Riad El Solh 110 72020 Beirut Lebanon

AIM: To study the efficacy of low-dose imipramine in relieving symptoms associated with the irritable bowel syndrome (IBS). METHODS: A randomized, double-blind trial of 25 mg imipramine vs matched placebo for 12 wk was performed. Doubling the dose was allowed once at week 2 in case of an unsatisfactory early response. Primary efficacy variables were subjective global symptom relief and quality of life (QoL) using SF-36 at week 12. RESULTS: One hundred and seven patients were enrolled by advertisement or referral by general practitioners and 56 (31 imipramine: 25 placebo) completed the 16-wk study. Baseline characteristics were comparable. A high overall dropout rate was noted in the imipramine and placebo arms (47.5% vs 47.9%, P > 0.05), a mean of 25.0 and 37.4 d from enrollment, respectively (P elief with imipramine over placebo (per-protocol: 80.6% vs48.0%, P = 0.01) and a trend on intent-to-treat (ITT) analysis (42.4% vs 25.0%, P = 0.06). This improvement was evident early and persisted to week 16 (P = 0.024 and 0.053 by per-protocol and ITT analyses, respectively). Mean cumulative and componentspecific SF-36 scores improved in the imipramine group only (per-protocol, P elated adverse events leading to patient dropout were more common in the imipramine group (25.4% vs 12.5%, P > 0.05). CONCLUSION: Imipramine may be effective in the treatment of IBS patients and is associated with improved QoL. Careful patient selection, initiation of a low dose with gradual escalation and monitoring for side effects may result in an improved therapeutic response.

关键词： Tricyclic antidepressants Quality of life Functional gastrointestinal disorders Irritable bowelsyndrome Pain

PHBV Crystallization under Injection Molding Conditions:Influence of Packing Pressure and Mold Temperature

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Journal of Renewable Materials 2018年第3期6卷 270-276页

作者： G.el hajj Sleiman G.Colomines R.Deterre I.Petit E.Leroy S.Belhabib UBL IUT NantesCNRSGEPEAUMR 6144OPERP2 Avenue du professeur Jean ROUXELBP 53944475 CarquefouFrance UBL CNRSGEPEAUMR 6144CRTT37Boulevard de l’Université44606 St Nazaire CedexFrance

Poly(3-hydroxy butyrate)-co-(3-hydroxy valerate)(PHBV)is a biobased and biodegradable *** semicrystalline bioplastic could be a good candidate for the replacement of some commodity plastics derived from ***,the control of the conditions of its processing in order to obtain optimal properties of the finished products remains a current research *** objective of this work is to better understand the crystallization under injection molding conditions by inline measurements during the *** focused on the influence of two key processing parameters,namely,mold temperature and packing *** modeling of inline temperature measurements allowed an inverse estimation of the thermodynamic melting temperature of PHBV and of the heat of crystallization’s variations with processing parameters.

关键词： Crystallization PHBV injection molding inline measurement

Use of Geomatic Approaches to Characterize Arqa River Basin: A Typical Coastal Lebanese River

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Open Journal of Modern Hydrology 2015年第3期5卷 45-57页

作者： Abdulrahim Ibrahim Moustafa Al hajj Mhamad el Hage Department of Geography (GISRS Lab) Lebanese University Tripoli Lebanon Centre for Language and Communication Studies Lebanese University Beirut Lebanon Department of Geography (GISRS Lab) and Department of Civil Engineering Lebanese University Tripoli Lebanon

Water resources in Lebanon are one of the major threatened natural resources, since they spread on different geographic locations creating a network of permanent and temporary watercourses that govern the socio-economy and livelihood. However, lately, these watercourses, and certainly the rivers and streams, are witnessing unfavorable impacts that make them with less benefit and use. In addition, most of the Lebanese river basins have not been characterized due to the newly physical challenges of climate change and the human interference. Hence, characterization of the Lebanese river basins must be obtained in order to monitor the changing of physical and anthropogenic parameters. This can help for better conservation and adaptation approaches, notably for climate change. Arqa River, a coastal Lebanese river in North Lebanon is a typical example. In this study, Arqa River basin and the occupied streams among it have been studied using new advanced geomatic techniques. These techniques are based on the treatment of digital geo-spatial data in systematic approaches. ArcGIS is the software which is used to elaborate and manipulate (data interrelation, measures, overlapping, ordering, etc.) the geo-spatial data. Thus, the geometric and morphometric analysis were obtained for the river catchment and the existing tributaries. This will be a primary tool for further applications including water resources management in the river system. This can be utilized in the execution of dams, mountain lakes, man-made channels and in mapping flood-prone areas. In addition, the obtained characterization of this basin will be helpful in mapping erosion processes and estimation of the infiltration capacity, plus monitoring surface water flow. It is a typical approach of analysis that can be applied for the rest of Lebanese river systems in order to attain a better water resources management. This study shows that the use of geomatic techniques is a very helpful tool in the study of basin

关键词： Geomatic Remote Sensing GIS DEM Morphometry

Cholangiocarcinoma in Patients with Crohn’s Disease

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Journal of Cancer Therapy 2015年第1期6卷 21-24页

作者： Tarek Debs Isabella Reccia Imad el-hajj Ziad el-Rassi Division of General and Visceral Surgery Saint George Hospital University Medical Centre Beirut Lebanon

Cholangiocarcinoma is an uncommon malignancy that increases with age. Cholangiocarcinoma has been linked to inflammatory bowel disease, and a relationship between inflammatory bowel disease, anti-tumour necrosis factor alpha antibody (Infliximab) and cholangiocarcinoma has been suggested. Although cholangiocarcinoma is usually associated with ulcerative colitis, recently more cases are being seen in association with Crohn’s disease. The risk of cancer in patients treated with Infliximab has been discussed, and whether Infliximab is associated with an increased risk of cholangiocarcinoma is not clear. Cholangiocarcinoma is an uncommon malignancy and it is difficult to establish a clear correlation with Infliximab treatment. A large number of reports are needed to further address these issues.

关键词： Cholangiocarcinoma Crohn’s Inflammatory Bowel Disease Infliximab

Sexual Perception of Young Lebanese Students

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Health 2017年第2期9卷 299-316页

作者： Ghada Bteich Mariana hajj eliane Accaoui Abir el Abed Faculty of Public Health Lebanese University Branch V Saida Lebanon Faculty of Human Science Lebanese University Dekkwayne Lebanon

This article presents the sexual perception of young Lebanese students. We hypothesized that, in Lebanon and the Arab countries, premarital sex is forbidden by most cultures because of conservative societies and backgrounds. Sexuality lives as a “myth” in these conservative societies. We examined the influence of demographics and genders among a group of 706 Lebanese university students, from public and private universities, as well as the fluctuation of sexual beliefs and practices, based on their gender, demographics and social pressure. The method used was a questionnaire collected form n = 706 students, 446 females and 260 males. The female population of our sample is 62.9% of the total volunteers while the male population is 36.7%. They come from different religions (Christian, Muslim, Druze and Other), between May 2015 and December 2015. Quantitative significant results: 1) A non-conformity with the social and demographic pressure and an openness of the new generations. Similarly, it shows more permissiveness in flirting. Even though, parts of the negative answers were significantly linked to understanding the rules of prohibited sex (NO 32.4% for belief and NO 34.5% for practice);2) the reality of Lebanese youth, their integrity in engaging in a relationship, and their true daily happening of social and peer pressure;3) An opening to a natural outlook of sexual life, (25.5%) with reluctance on dating (51.1%);4) An important significance is showed in the percentage between beliefs and practice: 18% in belief and 78.3% in practice (Q1) and 34.2% in belief and 60.8% in practice (Q2) emphasizing on the reality of sexual engagement within Lebanese youth;5) However, reluctance in engaging in sexual activity and attachment and fear to social sanctions toward premarital sex and agreeing on abstinence before marriage. Quantitative findings supported the lack of sexual education and the prevalence of religious and social norms. This article examines Young Lebanese adol

关键词： Young Lebanese Adolescents University Students Sexuality Perception Premarital Sex Sex Education Dating