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Advances in Chemical Engineering and Science 2023年第3期13卷 224-240页

作者： juan j. Musci María E. Chiosso Guillermo j. Siri Mónica L. Casella Departamento de Ciencias Básicas y Experimentales Universidad Nacional del Noroeste de la Provincia de Buenos Aires Junín Argentina Centro de Investigaciones y Transferencia del Noroeste de la Provincia de Buenos Aires (CITNOBA) - UNNOBA-UNSAdA-CONICET Pergamino Argentina Centro de Investigación y Desarrollo en Ciencias Aplicadas “Dr. jorge j. Ronco” (CINDECA) CCT CONICET-La Plata Universidad Nacional de La Plata Comisión de Investigaciones Científicas La Plata Argentina

The catalytic hydrogenation of D-glucose over a 3 wt% Ru/C catalyst was studied varying the operating conditions in mild conditions range to optimize the obtention of D-sorbitol. The stirring speed, temperature, pressure, and initial glucose concentration were varied between 250 - 700 rpm, 343 - 383 K, 0.5 - 2 MPa, and 0.033 - 0.133 M, respectively. To verify the absence of mass transport limitations, the diffusion of reagents in the gas-liquid interface, the liquid-solid interface, and the internal diffusion in the particles were evaluated. Under the operating conditions studied, the reaction rate showed an order with respect to H2 of 0.586 and with respect to glucose of 0.406. The kinetic data were adjusted using 3 general models and 19 different sub-models based on Langmuir-Hinshelwood-Hougen-watson (LHHW) kinetics. Model 3a was the best one interpreting the aqueous phase hydrogenation of glucose (both reagents competitively adsorbed on the catalyst). The H2 adsorption is dissociative and the rate-limiting step is the surface chemical reaction.

关键词： 3 wt% Ru/C D-Glucose Hydrogenation Kinetic Modeling

体外干细胞培养扩增同种异体移植物眼表重建的结果及DNA分析

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世界核心医学期刊文摘（眼科学分册） 2005年第7期1卷 57-57页

作者： Daya S.M. watson A. Sharpe j.R. 宋虎平 Corneo- Plastic Unit and Eye Bank Queen Victoria Hospital West Sussex RH19 3DZ United Kingdom

Purpose: To investigate the outcome of a new technique of ex vivo expanded stemcell allograft for limbal stemcell deficiency (LSCD), and to characterize the ocular surface genotype after surgery. Design: Retrospective noncomparative case series. Participants: Ten eyes of 10 patients with profound LSCD arising from ectodermal dysplasia (3 eyes), Stevens- johnson syndrome (3 eyes), chemical injury (2 eyes), thermal injury (1 eye), and rosacea blepharoconjunctivitis (1 eye). Intervention: Allogeneic corneal limbal stem cells were cultured on plastic and transplanted to the recipient eye after removal of conjunctival pannus. Amniotic membrane was applied in a bandage capacity. The procedure was combined with other reconstructive surgery in 2 cases. Nine patients received systemic cyclosporinAimmunosuppression, and the DNA genotypewas investigated with surface impression cytology. Main Outcome Measures: Parameters of LSCD, including vascularization, conjunctivalization, inflammation, epithelial defect, photophobia, and pain. Results: The mean follow- up period was 28 months (range, 12- 50). Seven of 10 eyes (70% ) had improved parameters of LSCD at final follow- up and were considered successes. Four (40% ) had improved visual acuity, including 3 having had further procedures for visual rehabilitation. Three patients failed to improve- 1 with a thermal burn and lid deformity, 1 with Stevens- johnson syndrome and severe dry eye, and 1 with ectodermal dysplasia who developed an epithelial defect at 26 months. DNA analysis of the first 7 cases showed no ex vivo donor stem cell DNA present beyond 9 months. Conclusions: Ex vivo expanded stem cell allograft is a useful technique for restoring the ocular surface in profound LSCD. The absence of donor DNA beyond 9 months suggests that ongoing immunosuppression may be unnecessary and raises questions regarding the origin of the host corneal epithelium.

关键词：眼表重建 DNA分析干细胞培养同种异体移植热烧伤角膜血管化上皮缺损血管翳化学烧伤细胞移植

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8例皮肤白血病患者的临床表现、治疗和预后

世界核心医学期刊文摘（皮肤病学分册） 2006年第5期2卷 27-27页

作者： watson K.M.T. Mufti G. Salisbury j.R. 刘艳 Department of De rmatology King' s College Hospital Denmark Hill London SE5 9RS United Kingdom

All types of leukaemia can disseminate to the skin, producing cutaneous deposits known as leukaemia cutis (LC). We undertook a retrospective study to review the clinical presentations, treatment and outcome of eight patients with LC managed in our department over a period of 12 years. The clinical phenotype varied, with erythematous papules and nodules occurring with greatest frequency. Infiltrated haemorrhagic plaques and peri follicular acneiform papules were also seen. Although patients were treated aggressively for their underlying leukaemia, and received therapy directed towards LC, they tended to be refractory to treatment and the diagnosis was generally associated with a poor prognosis. The exception was a patient with chronic lymphocytic leukaemia, who survived 3 years after developing LC.

关键词：皮肤白血病红色丘疹

Accelerating materials discovery using artificial intelligence, high performance computing and robotics

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npj Computational Materials 2022年第1期8卷 767-775页

作者： Edward O.Pyzer-Knapp jed W.Pitera Peter W.j.Staar Seiji Takeda Teodoro Laino Daniel P.Sanders james Sexton john R.Smith Alessandro Curioni IBM Research Europe-Daresbury DaresburyUK IBM Almaden Research Centre San JoseCAUSA IBM Research Europe Zurich RüschlikonSwitzerland IBM Research Tokyo TokyoJapan IBM Thomas j.watson Research Centre Yorktown HeightsNYUSA

New tools enable new ways of working,and materials science is no *** materials discovery,traditional manual,serial,and human-intensive work is being augmented by automated,parallel,and iterative processes driven by Artificial Intelligence (AI),simulation and experimental *** this perspective,we describe how these new capabilities enable the acceleration and enrichment of each stage of the discovery *** show,using the example of the development of a novel chemically amplified photoresist,how these technologies’ impacts are amplified when they are used in concert with each other as powerful,heterogeneous workflows.

关键词： artificial computing enable

正、负性情绪的跨文化心理测量:PANAS维度结构检验

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心理科学 2004年第1期27卷 77-79页

作者：张卫东刁静 Constance j.Schick 华东师范大学心理学系上海200062 美国Bloomsburg大学心理学系 pa17815

对中国大学生 (N =2 0 1 )和美国大学生 (N =32 1 )进行PANAS测评 ,以检验该量表中、英文版的因素效度。探索性因素分析会聚性地验证了该量表的PA和NA两维度结构具有跨文化一致性 ,中、英文量表两因子的累积方差贡献率分别为 51 .31 %和... 详细信息

对中国大学生 (N =2 0 1 )和美国大学生 (N =32 1 )进行PANAS测评 ,以检验该量表中、英文版的因素效度。探索性因素分析会聚性地验证了该量表的PA和NA两维度结构具有跨文化一致性 ,中、英文量表两因子的累积方差贡献率分别为 51 .31 %和 44 .2 5 % ,接近watson等的研究结果。然而研究结果也显示测项偏差问题 ,因此中文量表的PA分量表的测项组成不等同于原量表。中、英文量表的PA与NA分量表同样具有较高内在一致性信度。

关键词：正性情绪负性情绪跨文化心理测量 PA维度结构 NA维度结构

近期临床实践中美国商业保险患者的调脂药停药情况

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世界核心医学期刊文摘（心脏病学分册） 2007年第7期3卷 23-23页

作者： Kamal-Bahl S.j. Burke T. watson D. Wentworth C. 杜媛 Outcomes Research and Management West Point PA United States Dr.

尽管有数种调脂药（LMD）治疗和调脂策略可用于成功地治疗具有心血管事件危险的患者，但是药物治疗的益处只有长期坚持应用才能体现。既往关于LMD停药率的观察研究并不能代表美国当前临床实践中的情况。本研究在一个来自不同地域、纳入... 详细信息

尽管有数种调脂药（LMD）治疗和调脂策略可用于成功地治疗具有心血管事件危险的患者，但是药物治疗的益处只有长期坚持应用才能体现。既往关于LMD停药率的观察研究并不能代表美国当前临床实践中的情况。本研究在一个来自不同地域、纳入商业保险的美国人群中比较了近期临床实践中各类新采用LMD的停药情况。根据IngenixLab／Rx数据库确定2001年1月1日至2003年6月30日间年龄≥20岁并新服用他汀类药物、缓释烟酸、贝特类药物、胆酸螯合剂或依泽替米贝的患者。LMD停药定义为患者最近一次处方180d内不采用同一类LMD药物。

关键词：临床实践美国人群商业保险停药率调脂药药物治疗心血管事件他汀类药物

Phase 3 trial of first generation protease inhibitor therapy for hepatitis C virus/human immunodeficiency virus coinfection

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World journal of Hepatology 2017年第4期9卷 217-223页

作者： Kenneth E Sherman Minhee Kang Richard Sterling Triin Umbleja Kristen Marks jennifer j Kiser Beverly Alston-Smith Wayne Greaves Adeel A Butt 无 Division of Digestive Diseases University of Cincinnati College of Medicine harvard T.h. Chan School of Public health Department of Gastroenterology Virginia Commonwealth University Division of Infectious Disease Weill Cornell Medical School University of Colorado School of Pharmacy NIAID-Division of AIDS Merck and Co Inc. University of Pittsburgh School of Medicine hamad healthcare Quality Institute the ACTG 5294 BIRTH Study Team

AIMTo evaluate efficacy/safety of hepatitis C virus (HCV) protease inhibitor boceprevir with pegylated interferon (PEG-IFN) alfa and weight-based ribavirin (RBV) in a phase 3 trial. METHODSA prospective, multicenter, phase 3, open-label, single-arm study of PEG-IFN alfa, weight-based RBV, and boceprevir, with a PEG-IFN/RBV lead-in phase was performed. The HCV/human immunodeficiency virus coinfected study population included treatment naïve (TN) and treatment experienced (TE) patients. Treatment duration ranged from 28 to 48 wk dependent upon response-guided criteria. All patients had HCV Genotype 1 with a viral load > 10000 IU/mL. Compensated cirrhosis was allowed. Sample size was determined to establish superiority to historical (PEG-IFN plus RBV) rates in sustained viral response (SVR). RESULTSA total of 257 enrolled participants were analyzed (135 TN and 122 TE). In the TN group, 81.5% were male and 54.1% were black. In the TE group, 76.2% were male and 47.5% were white. Overall SVR12 rates (HCV RNA P = 0.002). Among the TN, SVR12 was 42.1% among whites and 27.4% among blacks (P = 0.09). CONCLUSIONThe trial met its hypothesis of improved SVR compared to historical controls but overall SVR rates were low. All-oral HCV treatments will mitigate these difficulties.

关键词： Human immunodeficiency virus Hepatitis C virus Boceprevir Pegylated interferon alfa Ribavirin

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恶性梅毒

世界核心医学期刊文摘（皮肤病学分册） 2005年第6期1卷 21-21页

作者： watson K.M.T. White j.M.L. Salisbury j.R. Creamer D. 牛新武 Department of Dermatology King's College Hospital London SE5 9RS United Kingdom

The incidence of syphilis in the UK is rising, particularly in HIV-positive men. We describe a Caucasian, HIV-negative woman who presented with secondary syphilis taking the form known as lues maligna. She also demonstrated the prozone phenomenon whereby the rapid plasmin reagin test was negative, but the Venereal Disease Research Laboratory and Treponema pallidum haemagglutination tests were positive.

关键词：恶性梅毒二期梅毒梅毒螺旋体反应素高加索人前带现象纤维蛋白溶酶检查和

Search for the rare decay B^(0)→j/ψФ

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Chinese Physics C 2021年第4期45卷 47-60页

作者： R.Aaij C.Abellin Beteta T.Ackernley B.Adeva M.Adinolfi H.Afsharnial C.A.Aidala S.Aiola Z.Ajaltouni S.Akar j.Albrecht F.Alessio M.Alexander A.Alfonso Albero Z.Aliouche G.Alkhazov P.Alvarez Cartelle S.Amato Y.Amhis L.An L.Anderlini A.Andreianov M.Andreotti F.Archilli A.Artamonov M.Artuso K.Arzymatov E.Aslanides M.Atzeni B.Audurier S.Bachmann M.Bachmaver j.j.Back S.Baker P.Baladron Rodriguez V.Balagura W.Baldinit j.Baptista Leite R.j.Barlow S.Barsuk W.Barter M.Bartolini F.Baryshnikov j.M.Basels G.Bassi B.Batsukh A.Battig A.Bay M.Becker F.Bedeschis I.Bediaga A.Beiter V.Belavin S.Belin V.Bellee K.Belous I.Belov I.Belyaev G.Bencivenni E.Ben-Haim A.Berezhnoy *** D.Berninghoff H.C.Bernstein C.Bertella E.Bertholet A.Bertolin C.Betancourt F.Betti M.O.Bettler Ia.Bezshyiko S.Bhasin j.Bhom L.Bian M.S.Bieker S.Bifani P.Billoir M.Birch F.C.R.Bishop A.Bizzeti M.Biorn M.P.Blago T.Blake F.Blanc S.Blusk D.Bobulska j.A.Boelhauve O.Boente Garcia T.Boettcher A.Boldyrev A.Bondar N.Bondar S.Borghi M.Borisyak M.Borsato j.T.Borsuk S.A.Bouchiba T.j.V.Bowcock A.Boyer C.Bozzi M.j.Bradley S.Braun A.Brea Rodriguezs M.Brodski j.Brodzicka A.Brossa Gonzalo D.Brundu A.Buonaura C.Burr A.Burschee A.Butkevich j.S.Butter j.Buytaert W.Byczynski S.Cadeddu H.Cai R.Calabrese L.Calefice L.Calero Diaz S.Cali R.Calladine M.Calvi M.Calvo Gomez P.Camargo Magalhaes A.Camboni P.Campana D.H.Campora Perez A.F.Campoverde Quezada S.Capelli L.Capriotti A.Carbonel G.Carboni R.Cardinale A.Cardini I.Carli P.Carniti L.Carus K.Carvalho Akiba A.Casais Vidal G.Casse M.Cattaneo G.Cavallero S.Celani j.Cerasoli A.j.Chadwick M.G.Chapman M.Charles Ph.Charpentier G.Chatzikonstantinidis C.A.Chavez Barajas M.Chefdeville C.Chen S.Chen A.Chernov S.-G.Chitic V.Chobanova S.Cholak M.Chrzaszcz A.Chubykin V.Chulikov P.Ciambrone M.F.Cicala X.Cid Vidal G.Ciezarek P.E.L.Clarke M.Clemencic H.V.Cliff j.Closier j.L.Cobbledick V.Coco j.A.B.Coelho j.Cogan E.Cogneras L.Cojocariu P.Collins T.Colombo L.Congedo A.Contu N.Cooke G.Coombs G.Corti C.M.Costa Sobral B.Couturier D.C.Craik j.Crkovska M.Cruz Centro Brasileiro de Pesquisas Fisicas(CBPF) Riode JaneiroBrazil Universidade Federal do Riode janeiro(UFRj) Riode JaneiroBrazil Center for High Energy Physics Tsinghua UniversityBeijingChina School of Physics State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijingChina University of Chinese Academy of Sciences BeijingChina Institute Of High Energy Physics(IHEP) BejingChina Institute of Particle Physics Central China Normal UniversityWuhanHubeiChina Univ.Grenoble Alpes Univ.Savoie Mont BlancCNRSIN2P3-LAPPAnnecyFrance Universite Clermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix Marseille Univ CNRS/IN2P3CPPMMarseilleFrance Universitq Paris-Saclay CNRS/IN2P3IJCLabOrsayFrance LPNHE Sorbonne UniversiteParis Diderot Sorbonne Paris CiteCNRS/IN2P3ParisFrance I.Physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultat Physik Technische Universitat DortmundDortmundGermany Max-Planck-Institut fir Kernphysik(MPIK) HeidelbergGermany Physikalisches Institut Ruprecht-Karls-Universitat HeidelbergHeidelbergGermany School of Physics University College DublinDublinIreland INFN Sezione di Bari BariItaly INFN Sezione di Bologna BolognaItaly INFN Sezione di Ferrara FerraraItaly INFN Sezione di Firenze FirenzeItaly INFN Laboratori Nazionali di Frascati Frascatiltaly INFN Sezione di Genova GenovaItaly INFN Sezione di Milano Bicocca Milanolaly INFN Sezione di Milano MilanoItaly INFN Sezione di Cagliari Monserratoltaly Universita degli Studi di Padova Universita e INFNPadovaPadovaItaly INFN Sezione di Pisa PisaItaly INFN Sezione di Roma Tor Vergata RomaItaly INFN Sezione di Roma La Sapienza RomaItaly Nikhef National Institute for Subatomic Physics AmsterdamNetherlands Nikhef National Institute for Subatomic Physics and VU University Amsterdam AmsterdamNetherlands Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences KrakowPoland AGH-University of Science and Technology Faculty of Physics and Applied Computer Science

A search for the rare decay B^(0)→j/ψФis performed using Pp collision data collected with the LHCb dete-ctor at centre-of-mass energies of 7,8 and 13 TeV,corresponding to an integrated luminosity of9 *** significant signal of the decay is observed and an upper limitof 1.1x 10^(-7)at 90%confidence level is set on the branching fraction.

关键词： B physics flavour physics rare decay ω-Фmixing branching fraction