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Free bisphenol A(BPA),BPA-glucuronide(BPA-g),and total BPA concentrations in maternal serum and urine during pregnancy and umbilical cord blood at delivery

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Emerging Contaminants 2019年第1期5卷 279-287页

作者： warren g.foster Cariton Kubwabo Ivana Kosarac Sandra gregorovich garima Aryal Kaela Coleman Department of Obstetrics&gynaecology McMaster UniversityHamiltonOntarioL8S 4K1Canada Environmental Health Science and Research Bureau Health CanadaOttawaOntarioK1A 0K9Canada Tobacco Control Directorate Health CanadaOttawaOntarioK1A 0K9Canada

While adult exposure to total bisphenol A(BPA)has been well documented,developmental exposure to BPA and fetal exposure to the bioactive form(free BPA)remains poorly ***,pregnant women(n?199)between 28 and 35 weeks of pregnancy were invited to participate in this *** serum free of hemolysis(n?189)and urine(n?112)were collected at third trimester and delivery along with umbilical cord blood(UCB)at *** BPA,BPA mono-glucuronide(BPA-g)and total BPA concentrations were measured using gas chromatography coupled with tandem mass *** concentrations of free BPA were quantifiable above the method detection limit(MDL?0.026 ng/mL)in approximately 34%of serum samples in the third trimester and 21%of samples at delivery whereas BPA-g and total BPA were quantified in 43 and 70%of third trimester and delivery samples,*** geometric mean of free BPA,BPA-g and total BPA concentrations in maternal serum during the third trimester and at delivery were 0.62 ng/L andg/mL,and 0.24 and 0.31 ng/mL,*** mean urinary concentrations of free BPA,BPA-g,and total BPA(MDL?0.027 ng/mL)in the third trimester and delivery samples were 0.07 and 0.06 ng/mL,0.36 and 0.09 ng/mL,and 0.36 and 0.09 ng/mL,*** the UCB,the geometric means for free BPA,BPA-g,and total BPA concentrations were 0.05,0.08 and 0.10 ng/mL,*** results suggest that,in our study population,free BPA concentrations were low compared to other Canadian cohorts.

关键词： Bisphenol A Free BPA Conjugated BPA Pregnancy Exposure Fetal development Cord blood

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Evaluation of Ruminal Dry Matter Disappearance and pH of Dry Corn, High-Moisture Corn, and Rye under in Vitro Conditions

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Agricultural Sciences 2024年第3期15卷 327-332页

作者： warren Carl Rusche Zachary Kidd foster Smith South Dakota State University Brookings South Dakota USA

An in vitro experiment was conducted to evaluate the effects of grain type on in vitro dry matter disappearance (IVDMD) and pH using ruminal fluid and a buffer reagent. Five beef cows were used for ruminal fluid collection and ruminal fluid was pooled prior to use. The cows used for ruminal fluid collection were maintained on a forage-based diet (60:40 forage to concentrate) for 28 d prior to ruminal fluid collection. Three grain types were evaluated: 1) dry corn (89% dry matter;DRC), 2) high-moisture corn (72% dry matter;HMC) and 3) rye (89% dry matter;RYE). Data were analyzed as a completely randomized design. A total of twenty-one replications of each grain type were used for statistical analysis (n = 63 tubes total). IVDMD was greater (P ≤ 0.05) by 97.1% and 46.4% for RYE compared to DRC and HMC, respectively. Additionally, IVDMD was greater (P = 0.05) by 34.6% for HMC compared to DRC. Final pH was decreased (P ≤ 0.05) for RYE by 12.3% and 2.8% for RYE compared to DRC and HMC, respectively. Also, final pH was decreased (P = 0.05) by 9.8% for HMC compared to DRC. These data indicate that corn harvest method (dry vs. high-moisture) influences IVDMD and final pH and that rye has a greater disappearance of dry matter and lower final pH than corn under in vitro conditions.

关键词： Corn grain Processing Ruminal Fermentation Rye

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