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Effects of mercury contaminated rice from typical chemical plant area in China on nitric oxide changes and c-fos expression of rats brain

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Journal of Environmental Sciences 2005年第2期17卷 177-180页

作者： CHENGJin-ping wangwen-hua JIAJin-ping HUWei-xuan SHIWei LinXue-yu SchoolofEnvironmentalScienceandEngineering ShanghaiJiaotongUniversityShanghai200240China. SchoolofPublicHealth FudanUniversityShanghai200032China CollegeofEnvironmentandResources JilinUniversityChangchun130026China

China is one of countries with the highest mercury production in the world. The Guizhou Province in Southwestern China is currently one of the world's most important mercury production areas. In order to study the neurotoxicity of rice from Qingzhen Chemical Plant area and probe into the signal transduction molecular mechanism of injury in rat brain stimulation by mercury contaminated rice. The rats were exposed to mercury contaminated rice for 20 d. Both of the measurements of NO and NOS were processed according to the protocol of the kit. The effect of Hg contaminated rice on the expression of c-fos mRNA in rat brain and the expression of c-FOS protein in cortex, hippocampus were observed using reverse transcription polymerase chain reaction(RT-PCR) and immunocytochemical methods. The results showed the neural transmitter NO and NOS in brain were significantly change between exposure groups and control group; the mercury polluted rice induced significantly the expression of c-fos mRNA; the c-FOS positive cells in hippocampus and cortex of exposure groups were significant different from control group(p<0.01). It could be concluded that nitric oxide was involved in mercury contaminated rice induced immediate early gene c-fos expressions in the rat brain. Through food chain, local ecosystem and health of local people iave been deteriorated seriously by mercury. This serious situation will last a long period. In order to alleviate mercury pollution, more work needs to do.

关键词： chemical plant mercury contaminated rice c-fos NO NOS

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Screening of flocculant-producing microorganisms and flocculating activity

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Journal of Environmental Sciences 2004年第6期16卷 894-897页

作者： CHENGJin-ping ZHANGLan-ying wangwen-hua YANGYi-chen ZHENGMin JUSu-wei SchoolofEnvironmentalScienceandEngineering ShanghaiJiaotongUniversityShanghai200240China SchoolofEnvironmentandResources JilinUniversityChangchun130026China SchoolofLifeScienceandTechnology ShanghaiJiaotongUniversityShanghai200240China EnvironmentalProtectionBureauofMinhangDistrict ShanghaiShanghai200240China

A strain saccharomycete STSM-1 with high flocculanting activity was isolated from activated sludge with conventional methods. The high production rate and the low cost STSM-1 medium was obtained by selecting different kinds of media, carbon source, nitrogen source and inorganic salt ion. The best flocculant-producing conditions were found by changing medium initial pH, culture temperature and ventilation flow. The best flocculating effect was obtained by changing positive ion types, density and concentration of flocculant.

关键词： microbial flocculants flocculant-producing microorganisms flocculating activity

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Neurotransmitter level changes in domestic ducks(Shaoxing duck) growing up in typical mercury contaminated area in China

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Journal of Environmental Sciences 2005年第2期17卷 256-258页

作者： JIXiu-ling YANGLiu SHENZhe-min CHENGJin-ping JINGui-wen QULi-ya wangwen-hua SchoolofEnvironmentalScienceandEngineering ShanghaiJiaotongUniversityShanghai200240China GuizhouInstituteforEnvironmentalProtection Guiyang550002China

The neurotransmitter level changes of ducks exposed 8-month in a mercury-polluted site(Wanshan, China) and a reference site(Shanghai, China) were examined. Chemical analyses showed both higher mercury and selenium concentrations in the organ of Wanshan ducks. An increased content of acetylcholine(ACh) in brain and blood and a decreased activity of acetylcholinesterase(AChE) in blood were observed. Moreover, there was an increasing trend for nitric oxide synthase(NOS) activity and nitric oxide(NO) production in duck brain, but a reduction of NOS activity in duck serum. The possible explanations were due to the interactive effect of selenium accumulation and the sublethal exposure level of mercury in Wanshan area. The present study showed that AChE and NOS were sensitive to mercury contamination of real circumstance, suggesting that these two indexes have the potential to be biomarkers in assessment of health effects by mercury contamination.

关键词： mercury neurotransmitter long-term exposure Wanshan area

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Effect of methylmercury on some neurotransmitters and oxidative damage of rats

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Journal of Environmental Sciences 2005年第3期17卷 469-473页

作者： CHENGJin-ping YANGYi-chen HUWei-xuan YANGLiu wangwen-hua JIAJin-ping LINXue-yu SchoolofEnvironmentalScienceandEngineering ShanghaiJiaotongUniversityShanghai200240China CollegeofEnvironmentandResources JilinUniversityChangehun130026China

In order to study the molecular mechanism of injury in rat organs induced by methylmercury, and the relationship between neurotransmitter and oxidative damage in the toxicity process of rat injury by methylmercury was studied. The control group was physiological saline of 0.9%, the concentration of exposure groups were 5 mg/(kg5d) and 10 mg/(kg5d) respectively. The content of AChE, ACh, NOS, NO, MDA, SOD, GSH-Px and GSH in different organs of rats were determined with conventional methods. The results showed that after exposure to methylmercury for 7 d, the mercury content in brain of exposure groups increased clearly and had significant difference compared with the control group(P<0.01). In rat's brain, serum, liver and kidney, the content of ACh and AChE were all decreased; the content of NOS and NO were all increased; the content of MDA was increased compared with the control group, the exposure groups had significant difference (P<0.01); the content of SOD, GSH and GSH-Px was decreased compared with the control group, the exposure groups had significant difference(P<0.01). It could be concluded that methylmercury did effect the change of neurotransmitter and free radical. They participated in the toxicity process of injury by methylmercury. The damage of neurotransmitter maybe cause the chaos of free radical and the chaos of free radical may also do more damage to neurotransmitter vice versa.

关键词： methylmercury neurotransmitter oxidative damage

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Local magnetic moment oscillation around an Anderson impurity on graphene

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 192-201页

作者： Shuai Li Zhen Ma Jin-hua Gao School of Science Hebei University of Science and Technology School of Electronics and Information Zhengzhou University of Light Industry School of Physics and Wuhan National High Magnetic Field Center Huazhong University of Science and Technology

We theoretically investigate the spin resolved Friedel oscillation （FO） and quasiparticle interference （QPI） in graphene induced by an Anderson *** the impurity becomes magnetic,the resulted FO becomes spin dependent,which gives rise to a local magnetic moment oscillation with an envelop decaying as r-2in real space in the doping ***,at half filling,the electron density and local magnetic moment will not oscillate but decay as *** spin resolved FO has both sublattice and spin ***,the local magnetic moment decay at half filling only occurs at one sublattice of graphene,which is quite like the phenomenon observed in the STM experiment (***ález-Herrero et al.,Science 352,437 （2016）).We further give an analytic formula about such spin dependent FO based on the stationary phase ***,we study the interference of quasiparticles around the magnetic impurity by calculating the spin dependent Fourier-transformed local density of states （FT-LDOS）.Our work gives a comprehensive understanding about the local magnetic moment oscillation around an Anderson impurity on graphene.

关键词： Friedel oscillation local magnetic moment graphene Anderson impurity

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Linear Growth of Continuous-Wave Four-Wave Mixing with Dual Induced Transparency

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Communications in Theoretical Physics 2005年第1期43卷 165-168页

作者： wangwen-Yi LIJia-hua NationalKeyLaboratoryforLaserTechnique HuazhongUniversityofScienceandTechnologyWuhan430074China DepartmentofPhysics HuazhongUniversityofScienceandTechnologyWuhan430074China

Using Schroedinger-Maxwell formalism, we propose and analyze an opticalfour-wave mixing (FWM) scheme for the generation of coherent light in a coherent six-level atomicmedium based on dual electromagnetically induced transparency (EIT). We show that the significantlyenhanced conversion efficiency enabled by ultraslow propagation of pump waves has no directrelationship with the single-photon detuning, which is different from the FWM with a single EIT. Themost important feature is that our scheme is also capable of inhibiting and delaying the onset ofthe detrimental three-photon destructive interference that looks like a recent scheme [Phys. ***. 91 (2003) 243902] and may be used for generating short-wave-length coherent radiation.

关键词： optical four-wave mixing dual electromagnetically induced transparency Rabifrequency

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Electromagnetically Induced Transparency in a Four-Level Atomic System

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Communications in Theoretical Physics 2004年第1X期42卷 113-116页

作者： LIJia-hua wangwen-Yi DepartmentofPhysics HuazhongUniversityofScienceandTechnologyWuhan430074China NationalKeyLaboratoryforLaserTechnique HuazhongUniversityofScienceandTechnologyWuhan430074China

In this paper, we analyze and discuss the absorption properties of the probe beam in a four-level atomic system with a nearly hyper-fine doublet structure of two higher-lying excited levels based on electromagnetically induced transparency (EIT) for the two cases of transient process and steady-state process. The main gain of this work is to investigate theoretically the influence of the nearly hyper-fine levels on the probe absorption. For the transient process,using the numerical calculations by a simple Mathematica code we find that the magnitude of the probe absorption at the line center is small compared to the typical three-level atomic system in the context of electromagnetically induced transparency. For the case of the steady state, our results show that the probe absorption can be completely eliminated at the line center of the probe transition just as the usual three-level EIT scheme.

关键词：稳定态电磁诱导透彻性四层原子体系原子物理学量子干涉量子相关

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Analytical Method for Energy Spectra and Eigenstates in the Process of κ-Photon Down-Conversion with Quantized Pump

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Communications in Theoretical Physics 2003年第3X期40卷 293-298页

作者： LiJia-hua CHENAi-Xi wangwen-Yi DepartmentofPhysics HuazhongUniversityofScienceandTechnologyWuhan430074China WuhanInstituteofPhysicsandMathematics theChineseAcademyofSciencesWuhan430071China NationalKeyLaboratoryforLaserTechnique HuazhongUniversityofScienceandTechnologyWuhan430074China

In this paper, using the arguments of Wu et al. [Phys. Rev. Left. 86 (2001) 2200] we analytically discuss the energy spectra and corresponding eigenstates for the process of κ-photon down-conversion with quantized pump in a high-Q cavity by the aid of the computer programme. Remarkably, it is also shown that such a method can be used for solving numerically the equations in a much simpler manner than the previous ones.

关键词：量子光学分析方法能谱分析能量本征态 κ光子下转换非线性过程

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Crystal Structure of D-Valine at the Temperature of 293, 270, 223 and 173K

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Chinese Journal of Structural Chemistry 2003年第5期22卷 539-543,i001页

作者： wangwen-Qing GONGYan WANGZhe-Ming YANChun-hua InstituteofAppliedChemistry CollegeofChemistryPekingUniversityBeijing100871China StateKeyLaboratoryofRareEarthMaterials PekingUniversityBeijing100871China

The crystal structure of D-valine has been determined by Mo-Ka (l = 0.71073 ? X-ray diffraction method for the first time. It crystallizes in monoclinic, space group P21 (Z = 4) with a = 9.6728(5), b = 5.2722(3), c = 12.0425(8) ? = 90.750(2)?at 293 K. The asymmetric unit contains two crystallographically independent molecules A (trans form) and B (gauche I form). They are rotational isomers with two kinds of conformations about the Ca Cb bond. The results of measurements of crystal structure at 293, 270, 223 and 173 K show a little change in bond lengths and geometries as a function of temperature. No evidence was obtained for the existence of configuration transformation from D- to L-valine.

关键词： D-valine X-ray diffraction crystal structure low temperature

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New exploration on pathogenesis and early diagnosis of gestational diabetes

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World Journal of Clinical Cases 2025年第1期13卷 1-5页

作者： hua Bai Department of Neurology The Third Affiliated Hospital of Guizhou Medical UniversityDuyun 558099Guizhou ProvinceChina

Gestational diabetes mellitus(GDM)refers to varying degrees of abnormal glucose metabolism that occur during pregnancy and excludes patients pre-viously diagnosed with *** is a unique among the four subtypes of diabetes classified by the international World Health Organization *** GDM patients constitute a small proportion of the total number of diabetes cases,the incidence of GDM has risen significantly over the past decade,posing substantial risk to pregnant women and ***,it warrants considerable *** pathogenesis of GDM is generally considered to resemble that of type II diabetes,though it may have distinct *** blood biochemical proteins in the context of GDM can help elucidate its pathogenesis,thereby facilitating more effective prevention and management *** article reviews this critical clinical issue to enhance the medical community's sufficient understanding of GDM.

关键词： Gestational diabetes mellitus Pathogenesis Proteomics RBP4 ANGPTL8

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