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Online Fault-Tolerant Tracking Control With Adaptive Critic for Nonaffine Nonlinear Systems

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IEEE/CAA Journal of Automatica Sinica 2025年第1期 215-227页

作者： Ding wang Lingzhi hu Xiaoli Li Junfei Qiao IEEE the School of Information Science and Technology Beijing Key Laboratory of Computational Intelligence and Intelligent SystemBeijing Laboratory of Smart Environmental Protection and Beijing Institute of Artificial Intelligence Beijing University of Technology

In this paper, a fault-tolerant-based online critic learning algorithm is developed to solve the optimal tracking control issue for nonaffine nonlinear systems with actuator ***, a novel augmented plant is constructed by fusing the system state and the reference trajectory, which aims to transform the optimal fault-tolerant tracking control design with actuator faults into the optimal regulation problem of the conventional nonlinear error system. Subsequently, in order to ensure the normal execution of the online learning algorithm, a stability criterion condition is created to obtain an initial admissible tracking policy. Then, the constructed model neural network(NN) is pretrained to recognize the system dynamics and calculate trajectory control. The critic and action NNs are constructed to output the approximate cost function and approximate tracking control,respectively. The Hamilton-Jacobi-Bellman equation of the error system is solved online through the action-critic framework. In theoretical analysis, it is proved that all concerned signals are uniformly ultimately bounded according to the Lyapunov *** tracking control law can approach the optimal tracking control within a finite approximation error. Finally, two experimental examples are conducted to indicate the effectiveness and superiority of the developed fault-tolerant tracking control scheme.

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Epidemiological and clinical characteristics of 266 cases of intracerebral hemorrhage in Hangzhou,China

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第6期14卷 496-504页

作者： yun-zhen hu Jian-wen wang Ben-yan LUO Department of Pharmacy the First Affiliated HospitalSchool of MedicineZhejiang University Department of Neurology the First Affiliated HospitalSchool of MedicineZhejiang University

Ethnicity and socioeconomic factors can influence disease susceptibility,clinical presentation,and *** investigated the clinical characteristics(age,sex,seasonal variation,lesion site,symptoms,complications,prognosis,and sequelae) and risk factors for intracerebral hemorrhage(ICH) in 266 cases treated at our hospital in Hangzhou City,China,from January 2011 to December *** of ICH increased dramatically with age;only 4.3% of cases were 60 years of *** outnumbered women by 2:1(67.3% vs.32.7%).Single hemorrhage was most often located in the cerebral lobes(37.2% of cases),basal ganglia(34.2%),thalamus(8.3%),cerebellum(6.8%),ventricle(1.5%),and brainstem(1.1%),while 10.9% of cases exhibited hemorrhages at multiple *** was also a major risk factor for ICH,as 47% of all patients were hypertensive and the percentage increased with *** hypertensive patients,the most common hemorrhage site was the basal ganglia and ICH was often associated with *** patients with leukemia(all forms),most hemorrhages were *** encephalic operation-associated ICHs were all *** was the major symptom of occipital,temporal,and frontal lobe ***,nausea,and vomiting were the major symptoms of cerebellum *** dysfunction was the major symptom of thalamic and basal ganglia *** level of consciousness was the major symptom in multisite,ventricular,parietal lobe,and brainstem *** occurred most often in lobar hemorrhage and blurred vision in occipital lobe *** mortality was 24.4%(n=65) with a mean delay from presentation to death of(10.5±18.5) *** majority of fatalities were cerebral hernia cases(58.5%) and these patients also had the shortest time to death [(2.9±3.5) d].Mortality was 100% in brainstem ICH and hemorrhagic conversion of cerebral ***-associated ICH also had a high mortality rate(81.0%),while p

关键词： Intracerebral hemorrhage(ICH) Epidemiology Clinical characteristics Risk factor Outcome

The roles of ebolavirus glycoproteins in viral pathogenesis

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Virologica Sinica 2017年第1期32卷 3-15页

作者： yun-Jia Ning Fei Deng Zhihong hu hualin wang State Key Laboratory of Virology Wuhan Institute of Virology Chinese Academy of Sciences

Ebolaviruses are highly dangerous pathogens exhibiting extreme virulence in humans and nonhuman primates. The majority of ebolavirus species, most notably Zaire ebolavirus, can cause Ebola virus disease(EVD), formerly known as Ebola hemorrhagic fever, in humans. EVD is associated with case-fatality rates as high as 90%, and there is currently no specific treatment or licensed vaccine available against EVD. Understanding the molecular biology and pathogenesis of ebolaviruses is important for the development of antiviral therapeutics. Ebolavirus encodes several forms of glycoproteins(GPs), which have some interesting characteristics, including the transcriptional editing coding strategy and extensive O-glycosylation modification, clustered in the mucin-like domain of GP1, full-length GP(GP_(1,2)), and shed GP. In addition to the canonical role of the spike protein, GP_(1,2), in viral entry, ebolavirus GPs appear to have multiple additional functions,likely contributing to the complex pathogenesis of the virus. Here, we review the roles of ebolavirus GPs in viral pathogenesis.

关键词： ebolavirus glycoprotein (GP) mucin-like domain (MLD) cytotoxicity immune evasion inflammation pathogenesis

数智环境下价值网络对社区养老服务精准化的影响机理研究——基于扎根理论的探索

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现代情报 2025年第1期45卷 150-163页

作者：王新建胡广伟南京大学信息管理学院江苏南京210023 南京大学政务数据资源研究所江苏南京210023

[目的/意义]精准化是社区养老服务发展的主要目标,是衡量社区养老服务水平的重要标准。当前社区养老服务发展存在供需失衡,服务精准化水平不高。大数据、人工智能等数智环境飞速发展为社区养老服务精准化水平提升带来了历史机遇,而探索... 详细信息

[目的/意义]精准化是社区养老服务发展的主要目标,是衡量社区养老服务水平的重要标准。当前社区养老服务发展存在供需失衡,服务精准化水平不高。大数据、人工智能等数智环境飞速发展为社区养老服务精准化水平提升带来了历史机遇,而探索社区养老服务精准化水平的影响机理是更加有效提升服务精准化水平的前提。[方法/过程]基于价值网络模型,采用扎根理论研究方法,对社区养老服务相关参与主体代表的半结构化访谈语料进行编码分析,参照“背景-条件-行动-结果”的扎根理论经典范式,分析数智环境下价值网络对社区养老服务精准化的影响机理。[结果/结论]构建影响机理“火箭模型”,从宏观、中观、微观3个层面,分析价值网络对社区养老服务精准化水平的影响因素和作用机理,其中“数智技术赋能”是关键影响因素。研究回答了数智环境下价值网络对社区养老服务精准化的“影响机理是什么”的问题,为后续探索提升服务精准化水平的策略指明方向。

关键词：数智环境社区养老服务服务精准化价值网络模型扎根理论

Engineering titanium oxide-based support for electrocatalysis

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Journal of Energy Chemistry 2022年第4期31卷 168-183页

作者： Ke Chen Tao Shen yun Lu Yezhou hu Jingyu wang Jian Zhang Deli wang Key Laboratory of Material Chemistry for Energy Conversion and Storage(huazhong University of Science and Technology) Ministry of EducationHubei Key Laboratory of Material Chemistry and Service FailureSchool of Chemistry and Chemical EngineeringHuazhong University of Science and TechnologyWuhan 430074HubeiChina

The corrosion and weaker interaction with metal catalysts of common carbon supports during electrocatalysis push the development of alternative supports materials. Titanium oxide-based materials have been widely explored as electrocatalysts supports in consideration of their chemical stability, strong interactions with metal catalyst and wider applications in electrocatalytic reactions as well as the improved electronic conductivity. This review summarizes recent research advances in engineering titanium oxide-based supports for the catalysts in electrocatalysis field to provide guidance for designing high performance non-carbon supported electrocatalysts. Typically, the titanium oxide-based supports are classified into shaped TiO_(2), doped TiO_(2), titanium suboxide and TiO_(2)-carbon composites according to the modification methods and corresponding preparation methods. Then the engineering strategies and electrocatalytic applications are discussed in detail. Finally, the challenges, future research directions and perspectives of titanium oxide-based supports for electrocatalysis are presented for practical applications.

关键词： Titanium oxide support Electrocatalysis Strong metal-support interaction Electrochemical reactions

Use of bionic inspired surfaces for aerodynamic drag reduction on motor vehicle body panels

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第7期12卷 543-551页

作者： Xiao-wen SONG Guo-geng ZHANG yun wang Shu-gen hu Department of Mechanical Engineering Zhejiang University Hangzhou 310027 China

Inspired by the successful applications of biological non-smoothness,we introduced bionic non-smooth surfaces as appendices into vehicle body design,aiming to further reduce aerodynamic *** size range of the non-smooth units with pits and grooves was determined according to our analysis with the mechanisms underlying non-smooth unit mediated aerodynamic drag *** bionic non-smooth units reported here were designed to adapt the structure of a given vehicle body from the point of boundary layer control that reduces the burst and the loss of turbulent kinetic *** engine cover lid and vehicle body cap were individually treated with the non-smooth units,and the treated vehicles were subjected to aerodynamic drag coefficient simulation tests using the computational fluid dynamics(CFD) analysis *** simulation results showed that,in comparison with smooth surfaces,properly designed non-smooth surfaces can have greater effects on drag *** mechanism underlying drag reduction mediated by non-smooth surfaces was revealed by further analyses,in which the effects of non-smooth and smooth surfaces were directly compared.

关键词： Computational fluid dynamics(CFD) Bionics Non-smooth surface Aerodynamic drag reduction Vehicle body

Regulation of mTORC1 by amino acids in mammalian cells: A general picture of recent advances

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Animal Nutrition 2021年第4期7卷 1009-1023页

作者： Shizhe Zhang Xueyan Lin Qiuling Hou Zhiyong hu yun wang Zhonghua wang Key Laboratory of Ruminant Nutrition and Physiology College of Animal Science and TechnologyShandong Agricultural UniversityNo.61Daizong StreetTai'anShandongChina

The mechanistic target of rapamycin complex 1(mTORC1)integrates various types of signal inputs,such as energy,growth factors,and amino acids to regulate cell growth and proliferation mainly through the 2 direct downstream targets,eukaryotic translation initiation factor 4 E-binding protein 1(4 EBP1)and ribosomal protein S6 kinase 1(S6 K1).Most of the signal arms upstream of mTORCl including energy status,stress signals,and growth factors converge on the tuberous sclerosis complex(TSC)-Ras homologue enriched in brain(Rheb)*** acids,however,are distinct from other signals and modulate mTORCl using a unique *** recent years,the transmission mechanism of amino acid signals upstream of mTORCl has been gradually elucidated,and some sensors or signal transmission pathways for individual amino acids have also been *** the help of these findings,we propose a general picture of recent advances,which demonstrates that various amino acids from lysosomes,cytoplasm,and Golgi are sensed by their respective *** signals converge on mTORCl and form a huge and complicated signal network with multiple synergies,antagonisms,and feedback mechanisms.

关键词： mTORC1 Amino acids Leucine Mammal Signaling pathway

Permian-Triassic Magmatism in the Qin-Fang Tectonic Belt,SW China:New Insights into Tectonic Evolution of the Eastern Paleo-Tethys

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Journal of Earth Science 2023年第6期34卷 1704-1716页

作者： yun Zhou Yongshan Zhao Yongfeng Cai Qiaofan hu Ce wang Collaborative Innovation Center for Exploration of Nonferrous Metal Deposits and Efficient Utilization of Resources Guangxi Key Laboratory of Hidden Metallic Ore Deposits ExplorationGuilin University of TechnologyGuilin 541004China China Nonferrous Metals(Guilin)Geology and Mining Co. Ltd.Guilin 541004China School of Marine Sciences Sun Yat-sen UniversityZhuhai 519082China

The granites of ambiguous geodynamic mechanism in the Qin-Fang tectonic belt(SW China)were studied in detail based on petrological,element geochemical,zircon U-Pb geochronological,and Hf isotopic ***-ICPMS U-Pb analyses on zircon yield ages of 248-245 Ma for the granites from the Qin-Fang tectonic *** geochemical data show that they are high-K,calc-alkaline,and peraluminous *** ε_(Hf)(t)values are from -14.01 to -7.75 with two-stage model ages of 1.74-1.43 *** data,integrated with low Al_(2)O_(3)/TiO_(2),Rb/Sr,Rb/Ba,and(Na_(2)O+K_(2)O)/(FeO^(T)+MgO+TiO_(2))ratios,and high CaO/Na_(2)O ratios for the granite,suggest an origin from psammite source which was contaminated by mantle-derived *** observations,in combination with the age data and stratigraphic records in the Jinshajiang,Ailaoshan,and Hainan Island areas suggest that the granites were formed in a post-collision tectonic *** Qin-Fang tectonic belt was likely a branched ocean basin of the eastern Paleo-Tethys.

关键词： Paleo-Tethyan ocean zircon granite Permian-Triassic Qin-Fang tectonic belt

Electrochemistry and Electrocatalysis with Hemoglobin in DHP-PDDA Surfactant-Polymer Multibilayer Composite Films

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Chinese Chemical Letters 2001年第3期12卷 269-270页

作者： Nai Fei hu Hong yun LIU Li Wen wang Department of Chemistry Beijing Normal UniversityBeijing 100875

Polyionic complex DHP-PDDA was prepared by reacting anionic surfactant dihexadecyl phosphate (DHP) with polycationic poly(diallyldimethyl ammonium) (PDDA). Thin films made from DHP-PDDA with incorporated hemoglobin (H... 详细信息

关键词： Hemoglobin dihexadecyl phosphate poly(diallyldimethyl ammonium) multibilayer composite films electrochemistry electrocatalysis