检索结果-南通市图书馆

Subinterval Decomposition-Based Interval Importance Analysis Method

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2020年第9期124卷 985-1000页

作者： Wenxuan wang xiaoyi wang School of Mechatronic Engineering Lanzhou Jiaotong UniversityLanzhou730070China

The importance analysis method represents a powerful tool for quantifying the impact of input uncertainty on the output *** an input variable is described by a specific interval rather than a certain probability distribution,the interval importance measure of input interval variable can be calculated by the traditional non-probabilistic importance analysis ***,the non-probabilistic importance analysis methods involve the Monte Carlo simulation(MCS)and the optimization-based methods,which both have high computational *** order to overcome this problem,this study proposes an interval important analytical method avoids the time-consuming optimization ***,the original performance function is decomposed into a combination of a series of one-dimensional ***,the interval of each variable is divided into several subintervals,and the response value of each one-dimensional subsystem at a specific input point is ***,the obtained responses are taken as specific values of the new input variable,and the interval importance is calculated by the approximated performance *** with the traditional non-probabilistic importance analysis method,the proposed method significantly reduces the computational cost caused by the MCS and optimization *** the proposed method,the number of function evaluations is equal to one plus the sum of the subintervals of all of the *** efficiency and accuracy of the proposed method are verified by five *** results show that the proposed method is not only efficient but also accurate.

关键词： Importance analysis method interval variable subinterval decomposition performance function MCS

Toxicity evaluation in a paper recycling mill effluent by coupling bioindicator of aging with the toxicity identification evaluation method in nematode Caenorhabditis elegans

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2008年第11期20卷 1373-1380页

作者： wang, xiaoyi SHEN, Lulu YU, Hongxia wang, Dayong Department of Genetics and Developmental Biology Southeast University Nanjing 210009 China Key Laboratory of Developmental Genes Human Disease Ministry of Education Southeast University Nanjing 210009 China State Key Laboratory of Pollution Control and Resource Reuse School of the Environment Nanjing University Nanjing 210093 China

Toxicity identification evaluation (TIE) can be used to determine the specific toxicant(s) in industrial *** the current study,the authors have attempted to combine the advantages of the model organism,Caenorhabditis elegans,with the virtues of the TIE technique,to evaluate and identify the toxicity on aging from a paper recycling mill *** results indicate that only the toxicities from mixed cellulose (MC) filtration and EDTA treatment are similar to the baseline aging toxicity,suggesting ...

关键词： metals aging toxicity identification evaluation (TIE) Caenorhabditis elegans

Enhanced anaerobic digestion and sludge dewaterability by alkaline pretreatment and its mechanism

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2012年第10期24卷 1731-1738页

作者： Liming Shao xiaoyi wang Huacheng Xu Pinjing He State Key Laboratory of Pollution Control and Resources Reuse College of Environmental Science and EngineeringTongdi UniversityShanghai 200092China

To investigate the influences of alkaline pretreatment on anaerobic digestion （AD） and sludge dewaterability after AD, waste activated sludge was adjusted to different pH values （8, 9, 10, 1 1, 12） and placed at ambient temperature for 24 hr. The samples were then adjusted to the initial pH and subjected to 25 days of AD. The results showed that, when compared with the control （pH 6.8）, total suspended solids （TSS） and volatile suspended solids （VSS） reduction following pretreatment at pH 9-11 increased by 10.7%-13.1% and 6.5%- 12.8%, respectively, while biogas production improved by 7.2%-15.4%. Additionally, significant enhancement of sludge dewaterability after AD occurred when pretreatment at pH 8-9 was conducted. The proteins and carbohydrates transferred from the pellet and tightly bound extracellular polymeric substances （TB-EPS） fractions to the slime and loosely bound EPS （LB-EPS） fractions after pretreatment and during the AD process, and the concentrations of proteins and carbohydrates in the slime fraction had a good linear relationship with the normalized capillary suction time （CST）. During the AD process, the normalized CST was positively correlated with the organic materials in the loosely bound fraction of the sludge matrix （R2/〉 0.700, p 〈 0.01）, while it was negatively correlated with the organic materials in the tightly bound fraction （R2≥ 0.702, p 〈 0.01）. These results suggest that alkaline pretreatment could break the EPS matrix and release inner organic materials, thus influencing the efficiency of the AD process and dewaterability after AD.

关键词： waste activated sludge alkaline pretreatment digestibility dewaterability extracellular polymeric substances

Opportunities and challenges of incretin-based hypoglycemic agents treating type 2 diabetes mellitus from the perspective of physiological disposition

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2023年第6期13卷 2383-2402页

作者： Yaochen Xie Qian Zhou Qiaojun He xiaoyi wang Jincheng wang Center for Drug Safety Evaluation and Research Zhejiang Province Key Laboratory of Anti-Cancer Drug ResearchCollege of Pharmaceutical SciencesZhejiang UniversityHangzhou 310007China Department of Pharmacy Hangzhou Medical CollegeHangzhou 310053China Department of Nephrology the First Affiliated Hospital of Huzhou Teachers Collegethe First People's Hospital of HuzhouHangzhou 313000China

The treatment of patients with diabetes mellitus, which is characterized by defective insulin secretion and/or the inability of tissues to respond to insulin, has been studied for decades. Many studies have focused on the use of incretin-based hypoglycemic agents in treating type 2 diabetes mellitus(T2DM). These drugs are classified as GLP-1 receptor agonists, which mimic the function of GLP-1,and DPP-4 inhibitors, which avoid GLP-1 degradation. Many incretin-based hypoglycemic agents have been approved and are widely used, and their physiological disposition and structural characteristics are crucial in the discovery of more effective drugs and provide guidance for clinical treatment of ***, we summarize the functional mechanisms and other information of the drugs that are currently approved or under research for T2DM treatment. In addition, their physiological disposition, including metabolism, excretion, and potential drug drug interactions, is thoroughly reviewed. We also discuss similarities and differences in metabolism and excretion between GLP-1 receptor agonists and DPP-4 inhibitors. This review may facilitate clinical decision making based on patients' physical conditions and the avoidance of drug drug interactions. Moreover, the identification and development of novel drugs with appropriate physiological dispositions might be inspired.

关键词： T2DM Incretins-based hypoglycemic agents GLP-1 receptor agonists DPP-4 inhibitors Physiological disposition Metabolism Excretion Drug drug interactions

Reliable flight performance assessment of multirotor based on interacting multiple model particle filter and health degree

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2019年第2期32卷 444-453页

作者： Zhiyao ZHAO Peng YAO xiaoyi wang Jiping XU Li wang Jiabin YU School of Computer and Information Engineering Beijing Technology and Business University Beijing Key Laboratory of Big Data Technology for Food Safety Beijing Technology and Business University College of Engineering Ocean University of China

Multirotor has been applied to many military and civilian mission scenarios. From the perspective of reliability, it is difficult to ensure that multirotors do not generate hardware and software failures or performance anomalies during the flight process. These failures and anomalies may result in mission interruptions, crashes, and even threats to the lives and property of human ***, the study of flight reliability problems of multirotors is conductive to the development of the drone industry and has theoretical significance and engineering value. This paper proposes a reliable flight performance assessment method of multirotors based on an Interacting Multiple Model Particle Filter(IMMPF) algorithm and health degree as the performance indicator. First, the multirotor is modeled by the Stochastic Hybrid System(SHS) model, and the problem of reliable flight performance assessment is formulated. In order to solve the problem, the IMMPF algorithm is presented to estimate the real-time probability distribution of hybrid state of the established SHS-based multirotor model, since it can decrease estimation errors compared with the standard interacting multiple model algorithm based on extended Kalman filter. Then, the reliable flight performance is assessed with health degree based on the estimation result. Finally, a case study of a multirotor suffering from sensor anomalies is presented to validate the effectiveness of the proposed method.

关键词： Health degree Interacting multiple model Multirotor Particle filter Reliability and safety Reliable flight performance Unmanned aerial vehicles

Low-hysteresis,pressure-insensitive,and transparent capacitive strain sensor for human activity monitoring

在线全文

学校读者我要写书评

暂无评论

Microsystems & Nanoengineering 2022年第5期8卷 115-123页

作者： xiaoyi wang Yang Deng Peng Jiang Xingru Chen Hongyu Yu School of Integrated Circuits and Electronics Beijing Institute of TechnologyBeijingChina Department of Mechanical and Aerospace Engineering The Hong Kong University of Science and TechnologyKowloonHong KongChina

Wearable strain sensors have been widely used for human activity *** reported strain sensors have mainly focused on material engineering,high stretchability and large gauge *** works have focused on strain sensor’s robustness and reliability,including low hysteresis,good long-term stability,good electrode material stability,and low coupling effects under multi-input signals,which are the factors that limit practical strain sensor *** develop a high-performance strain sensor,we propose a flexible capacitive sensor structure with three-dimensional(3D)interdigital electrodes fabricated by vertically aligned carbon *** with a traditional resistive strain sensor and a capacitive strain sensor with vertical sandwich electrodes,a strain sensor with horizontal parallel interdigital electrodes can benefit from low cross talk in terms of the normal force and improve substrate ***,embedding 3D electrodes into the substrate improves ultrahigh robustness with a low-pressure coupling effect under normal ***,compared with other reported works,the electrode variation under strain is small(less than 1.6%),which means that the perturbation of inert properties on device performance is ***,the fabricated strain sensor achieves an ultralow hysteresis(0.35%),excellent pressure-insensitive performance(less than 0.8%),fast response(60 ms),good long-term stability,and good *** an application example,a flexible strain sensor was successfully demonstrated as a wearable device for the precise monitoring of different types of human activities,including bending of the finger,knee,elbow,wrist,and neck with large strain signals and small strain signals generated by a mouth-opening *** excellent performance indicates that the flexible strain sensor is a promising candidate for human motion detection,soft robotics,and medical care.

关键词： transparency electrode transparent

An Efficient Reliability-Based Optimization Method Utilizing High-Dimensional Model Representation and Weight-Point Estimation Method

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computer Modeling in Engineering & Sciences 2024年第5期139卷 1775-1796页

作者： xiaoyi wang Xinyue Chang Wenxuan wang Zijie Qiao Feng Zhang School of Mechatronic Engineering Lanzhou Jiaotong UniversityLanzhou730070China School of Electronic and Information Engineering Lanzhou Jiaotong UniversityLanzhou730070China School of Mechanics Civil Engineering and ArchitectureNorthwestern Polytechnical UniversityXi’anChina

The objective of reliability-based design optimization(RBDO)is to minimize the optimization objective while satisfying the corresponding reliability ***,the nested loop characteristic reduces the efficiency of RBDO algorithm,which hinders their application to high-dimensional engineering *** address these issues,this paper proposes an efficient decoupled RBDO method combining high dimensional model representation(HDMR)and the weight-point estimation method(WPEM).First,we decouple the RBDO model using HDMR and ***,Lagrange interpolation is used to approximate a univariate ***,based on the results of the first two steps,the original nested loop reliability optimization model is completely transformed into a deterministic design optimization model that can be solved by a series of mature constrained optimization methods without any additional *** numerical examples of a planar 10-bar structure and an aviation hydraulic piping system with 28 design variables are analyzed to illustrate the performance and practicability of the proposed method.

关键词： Reliability-based design optimization high-dimensional model decomposition point estimation method Lagrange interpolation aviation hydraulic piping system

A review of Fe_3O_4 thin films:Synthesis,modification and applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2018年第8期34卷 1259-1272页

作者： xiaoyi wang Yulong Liao Dainan Zhang Tianlong Wen Zhiyong Zhong Center for Applied Chemistry University of Electronic Science and Technology of China State Key Laboratory of Electronic Thin Film and Integrated Devices University of Electronic Science and Technology of China

Magnetite （Fe3O4） has been used for thousands of years as one of the important magnetic materials. The rapid developments of thin film technology in the past few decades attract the attention of material scientists on the fabrication of magnetite thin films. In this article, we present an overview of recent progress on Fe3O4 thin films. The widely used preparation methods are surveyed, and the effect of sub- strates is discussed. Specifically the modified Fe3O4 thin films exhibit excellent electrical and magnetic properties compared with the pure films. It is noteworthy that modified Fe3O4 thin films can be put into two categories：（1） doped films, where foreign metal ions substitute iron ions at A or B sites： and （2） hybrid films, where magnetite phases are mixed with other materials. Notably, Fe3O4 thin films show great potentials in many applications such as sensors and batteries. It is expected that the investigations of Fe3O4 thin films will give us some breakthroughs in materials science and technology.

关键词： Fe3O4 Thin film Preparation method Modified film Material science

女性生育因素对主、客观认知功能的影响：基于平阴队列的横断面研究

在线全文

学校读者我要写书评

暂无评论

中国全科医学 2025年第8期28卷 980-988+995页

作者：付春迎于瑞洪王琪李美玲王晓祎朱东山山东大学齐鲁医学院公共卫生学院流行病学系山东省济南市平阴县疾病预防控制中心

背景目前关于生育因素与认知功能的研究结论尚不一致，且缺少有关女性生育因素与主观认知功能的研究。目的探究女性生育因素与主、客观认知功能的关联，为认知功能下降及痴呆症的早期预防和干预提供理论依据。方法平阴队列于2023年7... 详细信息

背景目前关于生育因素与认知功能的研究结论尚不一致，且缺少有关女性生育因素与主观认知功能的研究。目的探究女性生育因素与主、客观认知功能的关联，为认知功能下降及痴呆症的早期预防和干预提供理论依据。方法平阴队列于2023年7月在济南市平阴县3个乡镇以多阶段整群随机抽样法抽取45～70岁的中老年人进行调研，获得有效样本2 165例。自行编制一般信息问卷，收集社会人口统计学信息、既往病史、生活方式、女性生育因素等信息。分别采用主观认知下降自测量表（SCD-Q9）和蒙特利尔认知评估基础量表（Mo CA-B）测量研究对象的主、客观认知功能。通过人体测量获得身高、体质量等信息，通过血液检测获得研究对象的载脂蛋白e4(APOE e4)等位基因分型。采用多因素Logistic回归分析探讨女性生育因素对主、客观认知功能的影响。采用局部加权回归（Loess）分析女性初潮年龄、绝经年龄、生育期长度与Mo CA-B得分的非线性关联。结果本研究基于基线人群，纳入1 044例已绝经女性，其中SCD-Q9得分异常率为48.37%(505/1 044),Mo CA-B得分异常率为67.43%(704/1 044)。多因素Logistic回归分析结果显示，生育3个及以上的女性比生育1个及以下的女性主观认知下降的风险更低（OR=0.59,95%CI=0.36～0.98）；母乳喂养时长18岁（OR=1.91,95%CI=1.09～3.35）、绝经年龄≤45岁（OR=1.61,95%CI=1.00～2.62）、生育期≤30年（OR=1.56,95%CI=1.07～2.29）或>40年（OR=2.22,95%CI=1.05～4.72）均与较差的客观认知功能有关（P18岁、早绝经（≤45岁）、生育期过长或过短均与较差的客观认知功能有关。应关注女性生育因素对认知功能的影响，以延缓认知功能下降的进程。

关键词：女性生育因素认知功能主观认知功能客观认知功能横断面研究