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Spectral-interferometry-based diff-iteration for high-precision micro-dispersion measurement

Photonics Research 2024年第6期12卷 1362-1370页

作者： WEI DU JINGSHENG HUANG yanG wang MAOZHONG ZHAO JUAN LI JUNTAO HE JINDONG wang WENFU ZHANG TAO ZHU Key Laboratory of Optoelectronic Technology&System(Ministry of Education) Chongqing UniversityChongqing 400044China State Key Laboratory of Transient Optics and Photonics Xi’an Institute of Optics and Precision MechanicsChinese Academy of SciencesXi’an 710119China

Precise measurement of micro-dispersion for optical devices(optical fiber,lenses,etc.)holds paramount significance across domains such as optical fiber communication and dispersion interference ***,due to its complex system,complicated process,and low reliability,the traditional dispersion measurement methods(interference,phase shift,or time delay methods)are not suitable for the accurate measurement of micro-dispersion in a wide spectral ***,we propose a spectral-interferometry-based diff-iteration(SiDi)method for achieving accurate wide-band micro-dispersion *** an optical frequency comb,based on the phase demodulation of the dispersion interference spectrum,we employ the carefully designed SiDi method to solve the dispersion curve at any position and any *** approach is proficient in precisely measuring micro-dispersion across a broadband spectrum,without the need for cumbersome wavelength scanning processes or reliance on complex high-repetition-rate combs,while enabling adjustable *** efficacy of the proposed method is validated through simulations and *** employed a chip-scaled soliton microcomb(SMC)to compute the dispersion curves of a 14 m single-mode fiber(SMF)and a 0.05 m *** to a laser interferometer or the theoretical value given by manufacturers,the average relative error of refractive index measurement for single-mode fiber(SMF)reaches 2.8×10^(-6) and for glass reaches 3.8×10^(-6).The approach ensures high precision,while maintaining a simple system structure,with realizing adjustable resolution,thereby propelling the practical implementation of precise measurement and control-dispersion.

关键词： interferometer dispersion iteration

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“一带一路”沿线国家数字经济发展对中国跨境电商出口的影响效应研究

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现代财经（天津财经大学学报） 2024年第5期44卷 22-44页

作者：王艳盛小丹石河子大学经济与管理学院新疆石河子832000

跨境电商出口作为数字经济时代重要的新型贸易出口方式,为“一带一路”沿线国家的贸易合作注入新动能。本文运用2012-2021年世界银行数据库、UNCTAD数据库等构建多维面板数据,从直接和间接两个影响渠道分析和检验“一带一路”沿线国家... 详细信息

跨境电商出口作为数字经济时代重要的新型贸易出口方式,为“一带一路”沿线国家的贸易合作注入新动能。本文运用2012-2021年世界银行数据库、UNCTAD数据库等构建多维面板数据,从直接和间接两个影响渠道分析和检验“一带一路”沿线国家数字经济发展对中国跨境电商出口的影响。研究结果显示,在直接影响方面,“一带一路”沿线国家数字经济发展促进了中国跨境电商出口,且其影响具有异质性。在间接影响方面,降低贸易成本是促进中国跨境电商出口的中介渠道,沿线国家制度质量是促进中国跨境电商出口的调节因素。进一步空间效应分析表明,沿线国家数字经济发展对中国跨境电商出口具有空间溢出效应。本文的研究为深入推进“一带一路”沿线国家数字经济发展和促进我国跨境电商出口提供了重要启示。

关键词：数字经济跨境电商出口贸易成本制度调节

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咪达唑仑下调USP22抑制结肠癌SW480细胞增殖

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消化肿瘤杂志（电子版） 2012年第4期4卷 260-264页

作者：窦云凌刘卫峰王凌雁舒海华中山大学附属第一医院麻醉科广州510080

目的探讨咪达唑仑(midazolam)抑制人结肠癌SW480细胞增殖的可能机制。方法不同浓度咪达唑仑处理SW480细胞后,甲基偶氮唑蓝比色法(MTT)及BrdU掺入比色法检测细胞活性和增殖情况,Western blot及RT-PCR检测USP22蛋白及mRNA表达;构建USP22... 详细信息

目的探讨咪达唑仑(midazolam)抑制人结肠癌SW480细胞增殖的可能机制。方法不同浓度咪达唑仑处理SW480细胞后,甲基偶氮唑蓝比色法(MTT)及BrdU掺入比色法检测细胞活性和增殖情况,Western blot及RT-PCR检测USP22蛋白及mRNA表达;构建USP22干扰稳定细胞株,沉默USP22表达,Western blot检测USP22及细胞周期相关蛋白的表达水平。结果咪达唑仑呈时间和剂量依赖性抑制SW480细胞增殖。咪达唑仑浓度依赖性抑制USP22表达。si-USP-22能有效干扰USP-22蛋白及mRNA水平的表达,达到沉默USP-22的效果。干扰USP22后,肿瘤细胞增殖受抑制,CDK抑制蛋白P21及P27表达上调,干扰USP22可能通过CDKI/RB通路介导SW480细胞增殖抑制。结论咪达唑仑抑制人结肠癌SW480细胞增殖,可能机制为其下调USP22,通过CDKI/RB通路介导SW480细胞增殖抑制。

关键词：咪达唑仑 USP22 SW480细胞增殖

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2D Ca/Nb-based perovskite oxide with Ta doping as highly efficient H_(2)O_(2)synthesis catalyst

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Nano Research 2024年第6期17卷 4934-4942页

作者： Xingchen yang yang Gao Xiaohui Xu Wenqiang Xu Denghui wang Bin Luo Dong Liu Tao Liang Bin wang CAS Key Laboratory of Nanosystem and Hierarchical Fabrication National Center for Nanoscience and TechnologyBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Nanomaterials Centre School of Chemical Engineering and Australian Institute for Bioengineering and Nanotechnologythe University of QueenslandSt LuciaQLD 4072Australia State Key Laboratory of Organic–Inorganic Composites College of Chemical EngineeringCollege of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029China Hangzhou Institute for Advanced Study University of Chinese Academy of SciencesHangzhou 310024China State Key Lab of Silicon Materials Zhejiang UniversityHangzhou 310027China

Perovskite oxides(POs)are emerging as a class of highly efficient catalysts for reducing oxygen to H_(2)*** a rich variety of POs-based catalysts have been developed by tuning the complex composition,a highly efficient PO catalyst that is able to alter the reaction pathway from a 4e−process to a 2e−process for H_(2)O_(2)production has rarely been *** modified the structure and composition of a Ca-and Nb-based PO material by realizing a uniform two-dimensional(2D)morphology and varied Ta doping,resulting in the 2D Ca_(2)Nb_(3−x)Ta_(x)O_(10)−(x=0,0.5,1,and 1.5)monolayer *** obtained catalysts exhibit a dominant 2e−pathway and show exceptional H_(2)O_(2)production *** typical Ca_(2)Nb_(2.5)Ta_(0.5)O_(10)−nanoflakes showed an onset potential of 0.735 V *** hydrogen electrode(RHE),a remarkably high selectivity over 95%across a wide range of 0.3-0.7 V,an impressively high Faradaic efficiency of 94%,and a notable H_(2)O_(2)productivity of 1571 mmol·gcat^(−1)·h^(−1).These findings highlight the great potential of 2D perovskite oxide nanoflakes as advanced electrocatalysts for 2e−oxygen reduction reaction.

关键词： perovskite oxide H_(2)O_(2) two-electron oxygen reduction reaction catalyst Ca_(2)Nb_(3-x)Ta_(x)O_(10)-nanoflakes

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当归根腐病主要病原菌生物学特性及室内毒力测定

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微生物学杂志 2024年第2期44卷 71-78页

作者：张婷王艳晋玲吕娇娇高国香甘肃中医药大学药学院甘肃兰州730000 甘肃中医药大学药学院西北中藏药省部共建协同创新中心甘肃兰州730000

为探究当归(Angelica sinensis)根腐病的病原菌种类、生物学特性并筛选其防治药剂。采用常规组织法分离培养病原菌,利用柯赫氏法则验证其致病性,通过形态学和分子生物学相结合的方法进行病原菌的鉴定、生物学特性分析;采用菌丝生长速率... 详细信息

为探究当归(Angelica sinensis)根腐病的病原菌种类、生物学特性并筛选其防治药剂。采用常规组织法分离培养病原菌,利用柯赫氏法则验证其致病性,通过形态学和分子生物学相结合的方法进行病原菌的鉴定、生物学特性分析;采用菌丝生长速率法对病原菌进行室内毒力测定。结果表明,当归根腐病菌菌落毛毡状,在三种培养基上大型分生孢子呈镰刀形,大小为(27.5~47.5)μm×(3.8~7.5)μm(n=50),隔膜数1~5;小型分生孢子在PDA和SNA培养基上呈椭圆形、肾型、纺锤形,在CLA培养基上肾型,(3.8~15.0)μm×(2.5~7.5)μm(n=50),隔膜数0~3;厚垣孢子在CLA培养基上呈串生,PDA培养基上呈不规则形,SNA培养基上厚垣孢子着生方式多样,串生、圆形、不规则形,大小为(2.5~3.8)μm×(2.5~5.0)μm(n=50)。EF-1α、RPB1和RPB2联合序列系统发育树表明,该菌为锐顶镰刀菌(Fusarium acuminatum),其最适生长温度为25℃,最适生长初始pH为9,光照对其生长无显著影响。室内毒力测定显示10%苯醚甲环唑(WG)对其抑制效果最好,EC50值为83.71 mg/L。本研究可为当归根腐病病原鉴定及田间药剂防治提供参考。

关键词：当归根腐病病原鉴定生物学特性室内毒力

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基于置信学习的低标注率辐射源个体识别算法

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兵器装备工程学报 2024年第5期45卷 267-275页

作者：王艺卉闫文君凌青段可欣于楷泽海军航空大学山东烟台264001 中国人民解放军31401部队山东烟台264001 中国人民解放军91423部队山东烟台264001

针对仅有少量标签数据的样本弱标注情况下辐射源个体识别难的问题,提出了一种基于置信学习的伪标签校正的辐射源个体识别方法。首先通过动态调整类内置信度,实现生成伪标签地及时校正;其次,分析样本价值,对影响模型性能的少量关键样本... 详细信息

针对仅有少量标签数据的样本弱标注情况下辐射源个体识别难的问题,提出了一种基于置信学习的伪标签校正的辐射源个体识别方法。首先通过动态调整类内置信度,实现生成伪标签地及时校正;其次,分析样本价值,对影响模型性能的少量关键样本进行人工标注;然后利用联合交叉熵与中心损失函数,并叠加动态变化的伪标签置信度损失,同时关注类间、类内差异,最大化利用数据特征信息,实现的类内聚合和类间分离,最终实现了网络深度合理、精度与速度良好平衡的识别效果。实验结果表明:所提算法在有标记样本占比为5%、10%、20%、50%、100%等多种条件下,均可实现辐射源个体有效识别,尤其在有标签数据低占比的情况下优势明显,识别准确率分别突破70%与80%,有效减轻了有限标记样本的不足问题。

关键词：辐射源个体识别伪标签校正样本价值分析伪标签损失函数

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Correlative Mn-Co catalyst excels Pt in oxygen reduction reaction of quasi-solid-state zinc-air batteries

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Nano Research 2024年第5期17卷 4118-4124页

作者： Tingting wang Jincheng Huang Wei Sang Cai Zhou Bohan Zhang Wei Zhu Kang Du Zongkui Kou Shengxiang wang School of Mathematical and Physical Sciences Wuhan Textile UniversityWuhan 430200China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China

Zn-air batteries(ZABs)as a class of promising energy storage setups are generally powered by efficient and robust catalysts at the oxygen-involving *** the existing non-noble catalysts have outperformed noble Pt benchmark in the alkaline liquid-state ZABs,to the best of our knowledge few have excelled Pt in quasi-solid-state(QSS)***,we found that an integrated Mn-Co cathode derived from the bimetallic Mn/Co metal organic frameworks generates a 1.4-fold greater power density in the QSS ZABs than a Pt cathode while its power density in liquid-state ZABs is only 0.8-fold of the ***,such Mn-Co catalyst delivers high-rate oxygen reduction reaction(ORR)capability with half-wave potential of 0.84 *** in-depth characterizations and analyses have demonstrated that the Co and Mn species show the specific affinity towards H_(2)O and O_(2),respectively,synergizing the ORR process in the water-deficient environment of QSS *** work has enlightened the rational design of non-noble metal catalysts to improve the power density of QSS ZABs.

关键词： non-noble metal catalysts zinc-air battery quasi-solid-state synergistic effect

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Carboniferous integrative stratigraphy,biotas,and paleogeographical evolution of the Qinghai-Tibetan Plateau and its surrounding areas

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Science China Earth Sciences 2024年第4期67卷 1071-1106页

作者： Keyi HU Xiangdong wang Wenqi wang Yingfan SONG Xunyan YE Lu LI Yukun SHI Sunrong yanG Ying LI State Key Laboratory for Mineral Deposits Research School of Earth Sciences and Engineering and Frontiers Science Center for Critical Earth Material CyclingNanjing UniversityNanjing 210023China

During the Carboniferous Period,the Qinghai-Tibetan Plateau and its surrounding areas were located in quite different paleogeographic positions with various sedimentary and biological *** is important to systematically compile and summarize the Carboniferous strata and biotas of the Qinghai-Tibetan Plateau and its surrounding areas,to establish an integrated stratigraphic framework for correlation,and to reconstruct the paleogeography for correctly understanding the breakup of the Gondwana Continent and the evolution of the Paleo-Tethys Ocean in the Late *** Carboniferous of the Qinghai-Tibetan Plateau and its surrounding areas can be subdivided into the Gondwanan,Cimmerian,and Tethyan *** Gondwanan-type Carboniferous are distributed in the North Himalayan,Kangmar-Lhunze,and Zanda-Zumba regions of the South Tibet Subprovince and northern India-Pakistan Area,where only the Mississippian is developed and the biota is of Gondwanan *** Cimmerian-type Carboniferous,which are found in the Baoshan,Tengchong,Coqen-Xainza,LhasaZayu,Nagqu-Biru,and South Qiangtang regions,as well as Shan-Thai and South Afghanistan-Pamir areas,also represent only the Mississippian strata,but their biota is characterized by mixed characters of European,South China,Australian,and North American *** Tethyan-type Carboniferous are distributed in the Tanggula Mountains,Hoh Xil-Bayanhar,ChamdoHengduanshan,Tiekelike,West Kunlun,Karakorum,East Kunlun-Central Qinling,and Qilian regions,where the Carboniferous succession is well developed,and the biota is of warm-water Tethyan *** biostratigraphical correlation of the Gondwanan-type and Cimmerian-type Carboniferous is based mainly on conodonts and additionally on brachiopods and rugose *** Mississippian of the Tethyan-type Carboniferous is correlated mainly by using rugose corals and brachiopods,whereas in the Pennsylvanian foraminifera(fusuline)and conodonts are regarded as primary fossil groups,subord

关键词： Qinghai-Tibetan Plateau Carboniferous Lithostratigraphy Biota Stratigraphic correlation

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Engineering self-catabolic DNAzyme nanospheres for synergistic anticancer therapy

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Science China Chemistry 2024年第7期67卷 2412-2422页

作者： Yu Chen Yu Guo Jiaoli wang Ruiting Liu Xiaohai yang Kemin wang Ying Pu Hui Shi Jin Huang Key Laboratory of Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringKey Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan ProvinceHunan UniversityChangsha 410082China National Clinical Research Center for Geriatric Disorders Department of GeriatricsXiangya HospitalCentral South UniversityChangsha 410008China

DNAzyme-based gene therapy faces some challenges including cell penetration,activity limitation,and co-delivery ***-assembled DNA nanomedicine has attracted widespread attention due to its many *** is urgent to develop a universal DNA degradation strategy for precise programmable drug ***,we reported a self-catabolic DNAzyme nanospheres(SCNS),which could simultaneously achieve cell penetration,activity enhancement,and co-delivery *** SCNS were assembled through Y-DNA stepwise hybridization with each other,which were then loaded with aptamer(Apt),doxorubicin(Dox),and zinc oxide nanoparticles(ZnO NPs).The acid-triggered dissociation of ZnO NPs leads to the generation of Zn^(2+)ions cofactors for immediately self-catabolic DNAzyme *** the disassembly of the SCNS,three types of anticancer treatments would be activated,which include Zn^(2+)involved reactive oxygen species(ROS),Dox-induced chemotherapy,and DNAzyme-based gene *** experimental results show that the nanoplatform(Apt-SCNS-Dox-ZnO)has a good tumor-killing effect and minimal side *** a smart self-driven drug delivery nanoplatform,it is anticipated to displace extraordinary potential in biomedicine and bioengineering.

关键词： DNAzyme nanosphere ZnO NPs ROS Dox anticancer therapy

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3D-printed Mg-1Ca/polycaprolactone composite scaffolds with promoted bone regeneration

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Journal of Magnesium and Alloys 2024年第3期12卷 966-979页

作者： Xiao Zhao Siyi wang Feilong wang Yuan Zhu Ranli Gu Fan yang Yongxiang Xu Dandan Xia Yunsong Liu Department of Prosthodontics Peking University School and Hospital of StomatologyBeijing 100081China National Center of Stomatology National Engineering Laboratory for Digital and Material Technology of StomatologyNational Clinical Research Center for Oral DiseasesBeijing Key Laboratory of Digital StomatologyResearch Center of Engineering and Technology for Computerized Dentistry Ministry of HealthNMPA Key Laboratory for Dental MaterialsBeijing 100081China Department of Dental Materials Peking University School and Hospital of StomatologyBeijing 100081China

In bone tissue engineering,polycaprolactone(PCL)is a promising material with good biocompatibility,but its poor degradation rate,mechanical strength,and osteogenic properties limit its *** this study,we developed an Mg-1Ca/polycaprolactone(Mg-1Ca/PCL)composite scaffolds to overcome these *** used a melt blending method to prepare Mg-1Ca/PCL composites with Mg-1Ca alloy powder mass ratios of 5,10,and 20 wt%.Porous scaffolds with controlled macro-and microstructure were printed using the fused deposition modeling *** explored the mechanical strength,biocompatibility,osteogenesis performance,and molecular mechanism of the Mg-1Ca/PCL *** 5 and 10 wt%Mg-1Ca/PCL composites were found to have good ***,they promoted the mechanical strength,proliferation,adhesion,and osteogenic differentiation of human bone marrow stem cells(hBMSCs)of pure *** vitro degradation experiments revealed that the composite material stably released Mg_(2)+ions for a long period;it formed an apatite layer on the surface of the scaffold that facilitated cell adhesion and *** tomography and histological analysis showed that both 5 and 10 wt%Mg-1Ca/PCL composite scaffolds promoted bone regeneration bone *** results indicated that the Wnt/β-catenin pathway was involved in the osteogenic ***,Mg-1Ca/PCL composite scaffolds are expected to be a promising bone regeneration material for clinical *** of significance:Bone tissue engineering scaffolds have promising applications in the regeneration of critical-sized bone ***,there remain many limitations in the materials and manufacturing methods used to fabricate *** study shows that the developed Ma-1Ca/PCL composites provides scaffolds with suitable degradation rates and enhanced boneformation ***,the fused deposition modeling method allows precise control of the macroscopic morphology and microsc

关键词： 3D printing Bone tissue engineering Magnesium Osteogenic Polycaprolactone Scaffold.

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