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Partners of patients with ulcerative colitis exhibit a biologically relevant dysbiosis in fecal microbial metacommunities

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World Journal of Gastroenterology 2017年第25期23卷 4624-4631页

作者： Guang-Lan Chen Ye Zhang wang-Yue wang xue-Liang ji fei Meng Pei-Song xu Ning-Min Yang fu-qiang Ye Xiao-Chen Bo Department of Gastroenterology Lishui People's Hospital Department of Research Service Zhiyuan Medical Inspection Institute Co. LTD Department of Radiation Toxicology and Oncology Beijing Institute of Radiation Medicine People's Republic of China

AIM To investigate alterations in the fecal microbiome using 16 S r RNA amplicon sequencing in couples in the same cohabitation *** Fecal samples were collected from eight ulcerative colitis(UC) patients and their healthy partners at Lishui People's Hospital, Zhejiang Province, China. DNA was extracted and the variable regions V3 and V4 of the 16 S r RNA genes were PCR amplified using a two-step protocol. Clear reads were clustered into operational taxonomic units(OTUs) at the 97% sequence similarity level using UCLUST v1.2.22. The Wilcoxon rank-sumtest(R v3.1.2) was used to compare inter-individual differences. Differences with a P value < 0.05 were considered statistically *** Fecal microbial communities were more similar among UC patients than their healthy partners(P = 0.024). UC individuals had a lower relative abundance of bacteria belonging to the Firmicutes, especially Blautia, Clostridium, Coprococcus and Roseburia(P < 0.05). Microbiota dysbiosis was detected in UC patients and their healthy partners. Relevant genera included Akkermansiam, Bacteroides, Escherichia, Lactobacillales, Klebsiella and Parabacteroides. The enriched pathways in fecal samples of UC patients were related to lipid and nucleotide metabolism. Additionally, the pathways involved in membrane transport and metabolism of cofactors and vitamins were more abundant in the healthy *** Our results suggested that the microbial composition might be affected in healthy partners cohabiting with UC patients, especially in terms of microbiota dysbiosis.

关键词： Ulcerative colitis Patients Healthy partner Fecal microbial communities Microbiota dysbiosis

SoySNP618K array:A high-resolution single nucleotide polymorphism platform as a valuable genomic resource for soybean genetics and breeding

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Journal of Integrative Plant Biology 2022年第3期64卷 632-648页

作者： Yan-fei Li Ying-Hui Li Shan-Shan Su Jochen CReif Zhao-Ming Qi Xiao-Bo wang Xing wang Yu Tian De-Lin Li Ru-jian Sun Zhang-Xiong Liu Ze-Jun xu Guang-Hui fu Ya-Liang ji Qing-Shan Chen ji-qiang Liu Li-Juan Qiu The National Key Facility for Crop Gene Resources and Genetic Improvement(NFCRI)/Key Laboratory of Crop Gene Resource andGermplasm Enhancement(MOA)/Key Laboratory of Soybean Biology(Beijing)(MOA) Institute of Crop SciencesChinese Academy ofAgricultural SciencesBeijing 100081China Beijing Compass Biotechnology Co.Ltd Beijing 102206China Department of Breeding Research Leibniz Institute of Plant Genetics and Crop Plant Research(IPK)Gatersleben 06466Germany Key Laboratory of Soybean Biology in Chinese Ministry of Education(Key Laboratory of Soybean Biology and Breeding/Genetics ofChinese Agriculture Ministry) Northeast Agricultural UniversityHarbin 150030China School of Agronomy Anhui Agricultural UniversityHefei 230036China xuzhou Institute of Agricultural Sciences of xu-huai Region of jiangsu Xuzhou 221131China Department of Plant Genetics and Breeding China Agricultural UniversityBeijing 100193China Hulun Buir Institution of Agricultural Sciences ZhalantunInner Mongolia 021000China Suzhou Academy of Agricultural Sciences Suzhou 234000China

Innovations in genomics have enabled the development of low-cost,high-resolution,single nucleotide polymorphism(SNP)genotyping arrays that accelerate breeding progress and support basic research in crop ***,we developed and validated the Soy SNP618 K array(618,888 SNPs)for the important crop *** SNPs were selected from whole-genome resequencing data containing 2,214 diverse soybean accessions;29.34%of the SNPs mapped to genic regions representing 86.85%of the 56,044annotated high-confidence ***-by-state analyses of 318 soybeans revealed 17 redundant accessions,highlighting the potential of the Soy SNP618 K array in supporting gene bank *** patterns of population stratification and genomic regions enriched through domestication were highly consistent with previous findings based on resequencing data,suggesting that the ascertainment bias in the Soy SNP618 K array was largely compensated ***-wide association mapping in combination with reported quantitative trait loci enabled fine-mapping of genes known to influence flowering time,E2 and Gm PRR3 b,and of a new candidate gene,Gm ***,genomic prediction of flowering and maturity time in 502 recombinant inbred lines was highly accurate(>0.65).Thus,the Soy SNP618 K array is a valuable genomic tool that can be used to address many questions in applied breeding,germplasm management,and basic crop research.

关键词： functional single nucleotide polymorphism array gene discovery genomic selection genome-wide association studies marker-assisted selection soybean

Overproduction of OsRACK1A,an effector-targeted scaffold protein promoting OsRBOHB-mediated ROS production,confers rice floral resistance to false smut disease without yield penalty

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Molecular Plant 2022年第11期15卷 1790-1806页

作者： Guo-Bang Li jia-xue He jin-Long Wu He wang Xin Zhang jie Liu Xiao-Hong Hu Yong Zhu Shuai Shen Yi-fei Bai Zong-Lin Yao Xin-Xian Liu jing-Hao Zhao De-qiang Li Yan Li fu Huang Yan-Yan Huang Zhi-xue Zhao ji-Wei Zhang Shi-Xin Zhou Yun-Peng ji Mei Pu Peng Qin Shigui Li xuewei Chen jing wang Min He Weitao Li Xian-Jun Wu Zheng-Jun xu Wen-Ming wang jing Fan State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Sichuan Agricultural UniversityChengdu 611130China Rice Research Institute Sichuan Agricultural UniversityChengdu 611130China

Grain formation is fundamental for crop yield but is vulnerable to abiotic and biotic *** grain production is threatened by the false smut fungus Ustilaginoidea virens,which specifically infects rice floral organs,disrupting fertilization and seed ***,little is known about the molecular mechanisms of the ***-rice interaction and the genetic basis of floral ***,we report that *** secretes a cytoplasmic effector,UvCBP1,to facilitate infection of rice ***,UvCBP1 interacts with the rice scaffold protein OsRACK1A and competes its interaction with the reduced nicotinamide adenine dinucleotide phosphate oxidase OsRBOHB,leading to inhibition of reactive oxygen species(ROS)*** the analysis of natural variation revealed no OsRACK1A variants that could avoid being targeted by UvCBP1,expression levels of OsRACK1A are correlated with field resistance against *** in rice *** of OsRACK1A restores the OsRACK1A-OsRBOHB association and promotes OsRBOHB phosphorylation to enhance ROS production,conferring rice floral resistance to *** without yield *** together,our findings reveal a new pathogenic mechanism mediated by an essential effector from a flower-specific pathogen and provide a valuable genetic resource for balancing disease resistance and crop yield.

关键词： rice flower false smut fungal effector scaffold protein reactive oxygen species disease resistance

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不同水分条件对水稻需水量及产量影响

灌溉排水学报 2007年第5期26卷 82-85页

作者：季飞付强王克全徐淑琴东北农业大学水利与建筑学院哈尔滨150030

通过对水稻各个生育阶段实施不同程度的受旱,初步研究了查哈阳地区水稻在不同水分条件下的需水规律、生理特性以及其产量形成。结果表明:不同水分条件与水稻需水量及产量的关系非常密切。不同阶段的不同程度受旱对水稻生长发育的影响不... 详细信息

通过对水稻各个生育阶段实施不同程度的受旱,初步研究了查哈阳地区水稻在不同水分条件下的需水规律、生理特性以及其产量形成。结果表明:不同水分条件与水稻需水量及产量的关系非常密切。不同阶段的不同程度受旱对水稻生长发育的影响不尽相同,相同程度受旱对产量影响最大的阶段为拔节孕穗期;抽穗开花期次之,在分蘖期和灌浆期实施一定程度的水分亏缺不会对产量构成较大影响。

关键词：水稻受旱需水量产量

查哈阳灌区水稻水分生产函数模型及其应用试验研究

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灌溉排水学报 2008年第3期27卷 109-111页

作者：王克全付强季飞徐淑琴东北农业大学水利与建筑学院哈尔滨150030

在黑龙江省查哈阳灌区2006年实测数据的基础上,建立了4种水分生产函数模型,经过对4种水分生产函数模型的分析,初步确定出适合查哈阳灌区的水稻水分生产函数模型为Jensen模型,在此基础上建立了查哈阳灌区水稻的敏感指数累积函数,为该地... 详细信息

在黑龙江省查哈阳灌区2006年实测数据的基础上,建立了4种水分生产函数模型,经过对4种水分生产函数模型的分析,初步确定出适合查哈阳灌区的水稻水分生产函数模型为Jensen模型,在此基础上建立了查哈阳灌区水稻的敏感指数累积函数,为该地区水稻非充分灌溉条件下的灌溉制度优化提供了基础依据。

关键词：水稻水分生产函数 Jensen模型敏感指数累积函数

黑龙江省西部半干旱区水稻水分生产函数及优化灌溉制度研究

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节水灌溉 2007年第8期 48-51页

作者：王克全付强季飞徐淑琴东北农业大学水利与建筑学院黑龙江哈尔滨150030

选择黑龙江省西部半干旱区查哈阳灌区为试验基点,进行了水稻的非充分灌溉试验,经过数学分析计算,得到了查哈阳灌区水稻最适宜的水分生产函数模型为Jensen模型,在此基础上建立了水稻的优化灌溉制度的非线性规划模型,并利用实码加速遗传... 详细信息

选择黑龙江省西部半干旱区查哈阳灌区为试验基点,进行了水稻的非充分灌溉试验,经过数学分析计算,得到了查哈阳灌区水稻最适宜的水分生产函数模型为Jensen模型,在此基础上建立了水稻的优化灌溉制度的非线性规划模型,并利用实码加速遗传算法进行求解以相对产量最大为目标的优化灌溉制度,优化结果表明,优化灌溉定额比当地节水灌溉定额省水达22.4%,提高了水分利用效率,为查哈阳灌区水资源的优化利用提供了科学依据。

关键词：水稻水分生产函数非充分灌溉加速遗传算法优化灌溉制度

Frontiers in high entropy alloys and high entropy functional materials

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Rare Metals 2024年第10期43卷 4639-4776页

作者： Wen-Tao Zhang xue-Qian wang Feng-Qi Zhang Xiao-Ya Cui Bing-Bing Fan jia-Ming Guo Zhi-Min Guo Rui Huang Wen Huang xu-Bo Li Meng-Ru Li Yan Ma Zhi-Hua Shen Yong-Gang Sun De-Zhuang wang fei-Yang wang Li-qiang wang Nan wang Tian-Li wang Wei wang Xiao-Yang wang Yi-Han wang fu-jie Yu Yu-Zhen Yin Ling-Kun Zhang Yi Zhang jian-Yang Zhang Qi Zhao Yu-Ping Zhao Xin-Dong Zhu Yasir Sohail Ya-Nan Chen Tao Feng Qi-Long Gao Hai-Yan He Yong-jiang Huang Zeng-Bao jiao Hua ji Yao jiang qiang Li Xiao-Ming Li Wei-Bing Liao Huai-Jun Lin Hui Liu Qi Liu Qing-Feng Liu Wei-Di Liu Xiong-Jun Liu Yang Lu Yi-Ping Lu Wen Ma xue-fei Miao jie Pan Qing wang Hong-Hui Wu Yuan Wu Tao Yang Wei-Ming Yang Qian Yu jin-Yu Zhang Zhi-Gang Chen Liang Mao Yang Ren Bao-Long Shen xun-Li wang Zhe jia He Zhu Zhen-Duo Wu Si Lan School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing 210094China jiangsu Key Laboratory for Advanced Metallic Materials School of Materials Science and EngineeringSoutheast UniversityNanjing 211189China Department of Physics City University of Hong KongHongKong 999077China School of Materials Science and Engineering Tianjin UniversityTianjin 300072China School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China Department of Mechanical Engineering Research Institute for Advanced ManufacturingThe Hong Kong Polytechnic UniversityHong Kong 100872China Center of Electron Microscopy and State Key Laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027China Key Laboratory of Solidification Control and Digital Preparation Technology(Liaoning Province) School of Materials Science and EngineeringDalian University of TechnologyDalian 116024China Institute of Advanced Wear&Corrosion Resistance and functional Materials Jinan UniversityGuangzhou 510632China School of Mechanics and Civil Engineering China University of Mining and TechnologyXuzhou 221116China School of Physical Sciences Great Bay UniversityDongguan 523000China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 211816China Beijing Advanced Innovation Center for Materials Genome Engineering Research Institute for Carbon NeutralityUniversity of Science and Technology BeijingBeijing 100083China Department of Mechanical Engineering The University of Hong KongHong Kong 999077China School of Computing Macquarie UniversitySydney 2113Australia Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China State Key Laborato

Owing to their exceptional properties,high-entropy alloys(HEAs)and high-entropy materials have emerged as promising research areas and shown diverse ***,the recent advances in the field are comprehensively reviewed,organized into five *** first section introduces the background of HEAs,covering their definition,significance,application prospects,basic properties,design principles,and *** subsequent section focuses on cutting-edge high-entropy structural materials,highlighting developments such as nanostructured alloys,grain boundary engineering,eutectic systems,cryogenic alloys,thin films,micro-nano-lattice structures,additive manufacturing,high entropy metallic glasses,nano-precipitate strengthened alloys,composition modulation,alloy fibers,and refractory *** the following section,the emphasis shifts to functional materials,exploring HEAs as catalysts,magneto-caloric materials,corrosion-resistant alloys,radiation-resistant alloys,hydrogen storage systems,and materials for ***,the review encompasses functional high-entropy materials outside the realm of alloys,including thermoelectric,quantum dots,nanooxide catalysts,energy storage materials,negative thermal expansion ceramics,and high-entropy wave absorption *** paper concludes with an outlook,discussing future directions and potential growth areas in the *** this comprehensive review,researchers,engineers,and scientists may gain valuable insights into the recent progress and opportunities for further exploration in the exciting domains of high-entropy alloys and functional materials.

关键词： High entropy alloys Cutting-edge structural materials Cutting-edgefunctional materials

350MW火电机组热电解耦深度调峰技术研究

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汽轮机技术 2020年第5期62卷 389-392页

作者：李志强陈晓利高继录郑飞付强李博王东旭国家电投集团东北电力有限公司沈阳110181 中电投东北能源科技有限公司沈阳110179

针对东北地区某350MW火电机组,通过研究抽汽改造、抽汽改造+电极式水蓄热系统、抽汽改造+固体蓄热系统等3种热电解耦技术方案,综合考虑调峰收益、投资成本、占地面积等因素,确定了不同调峰目标下的最优深度调峰改造方案,并对最优方案的... 详细信息

针对东北地区某350MW火电机组,通过研究抽汽改造、抽汽改造+电极式水蓄热系统、抽汽改造+固体蓄热系统等3种热电解耦技术方案,综合考虑调峰收益、投资成本、占地面积等因素,确定了不同调峰目标下的最优深度调峰改造方案,并对最优方案的调峰收益进行分析。研究得出,综合考虑多种因素,当调峰目标40%时,抽汽改造方案为最优灵活性改造方案;当调峰目标30%时,抽汽改造+电极式锅炉水蓄热系统为最优方案。与抽汽改造方案相比,抽汽改造+电极式锅炉水蓄热系统方案调峰收益显著,年调峰收益比抽汽改造方案增加了223%,有效地提升了机组调峰能力。

关键词：火电机组热电解耦抽汽改造电极式水蓄热系统固体蓄热系统调峰能力

The first data release(DR1) of the LAMOST regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-Li Luo Yong-Heng Zhao Gang Zhao Li-Cai Deng Xiao-Wei Liu Yi-Peng jing Gang wang Hao-Tong Zhang jian-Rong Shi Xiang-Qun Cui Yao-Quan Chu Guo-Ping Li Zhong-Rui Bai Yue Wu Yan Cai Shu-Yun Cao Zi-Huang Cao Jeffrey L.Carlin Hai-Yuan Chen jian-Jun Chen Kun-Xin Chen Li Chen xue-Lei Chen Xiao-Yan Chen Ying Chen Norbert Christlieb jia-Ru Chu Chen-Zhou Cui Yi-Qiao Dong Bing Du Dong-Wei Fan Lei Feng jian-Ning fu Peng Gao xue-fei Gong Bo-Zhong Gu Yan-Xin Guo Zhan-Wen Han Bo-Liang He jin-Liang Hou Yong-Hui Hou Wen Hou Hong-Zhuan Hu Ning-Sheng Hu Zhong-Wen Hu Zhi-Ying Huo Lei jia Fang-Hua jiang Xiang jiang Zhi-Bo jiang Ge jin Xiao Kong xu Kong Ya-Juan Lei Ai-Hua Li Chang-Hua Li Guang-Wei Li Hai-Ning Li jian Li Qi Li Shuang Li Sha-Sha Li Xin-Nan Li Yan Li Yin-Bi Li Ye-Ping Li Yuan Liang Chien-Cheng Lin Chao Liu Gen-Rong Liu Guan-Qun Liu Zhi-Gang Liu Wen-Zhi Lu Yu Luo Yin-Dun Mao Heidi Newberg ji-Jun Ni Zhao-Xiang Qi Yong-Jun Qi Shi-Yin Shen Huo-Ming Shi jing Song Yi-Han Song Ding-qiang Su Hong-Jun Su Zheng-Hong Tang Qing-Sheng Tao Yuan Tian Dan wang Da-Qi wang Feng-fei wang Guo-Min wang Hai wang Hong-Chi wang jian wang jia-Ning wang jian-Ling wang jian-Ping wang Jun-Xian wang Lei wang Meng-Xin wang Shou-Guan wang Shu-Qing wang Xia wang Ya-Nan wang You wang Yue-fei wang You-Fen wang Peng Wei Ming-Zhi Wei Hong Wu Ke-fei Wu xue-Bing Wu Yu-Zhong Wu Xiao-Zheng Xing Ling-Zhe xu Xin-Qi xu Yan xu Tai-Sheng Yan De-Hua Yang Hai-Feng Yang Hui-Qin Yang Ming Yang Zheng-Qiu Yao Yong Yu Hui Yuan Hai-Bo Yuan Hai-Long Yuan Wei-Min Yuan Chao Zhai En-Peng Zhang Hua-Wei Zhang jian-Nan Zhang Li-Pin Zhang Wei Zhang Yong Zhang Yan-Xia Zhang Zheng-Chao Zhang Ming Zhao Fang Zhou xu Zhou jie Zhu Yong-Tian Zhu Si-Cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University Shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University Yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in June 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in June 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog