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Hierarchical Porous Carbon Counter Electrode for Dye-Sensitized Solar Cells

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Chinese Physics Letters 2011年第3期28卷 224-227页

作者： wang gui-qiang HUANG Cong-Cong XING Wei ZHUO Shu-Ping College of Chemical Engineering Shandong University of TechnologyZibo 255049

Hierarchical porous carbon is prepared by a combination of self-organization and chemical activation and explored as counter electrode for dye-sensitized solar *** structure analysis shows that micropores generated within the mesopore wall and the pristine mesopore structure of mesoporous carbon are preserved during KOH *** impedance spectroscopy studies demonstrate a relatively high electrocatalytic activity of hierarchical porous carbon electrode for triiodide reduction,as compared with a pristine mesoporous carbon *** enhanced electrocatalytic activity is beneficial for improving the photovoltaic performance of dyesensitized solar *** overall conversion efficiency of dye-sensitized solar cells with the hierarchical porous carbon electrode increased by 11.5%compared with that of the cell with a pristine mesoporous carbon electrode.

关键词： electrode Solar dye

The MELD scoring system for predicting prognosis in patients with severe hepatitis after plasma exchange treatment

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Hepatobiliary & Pancreatic Diseases International 2007年第5期6卷 492-496页

作者： Yu, Jian-Wu wang, gui-qiang Zhao, Yong-Hua Sun, Li-Jie wang, Shu-Qin Li, Shu-Chen Harbin Med Coll Dept Infect Dis Affiliated Hosp 2 Harbin 150086 Peoples R China Peking Univ First Hosp Dept Infect Dis Beijing 100034 Peoples R China

BACKGROUND: Hepatic failure caused by severe hepatitis is a clinical syndrome where the major liver functions, particularly detoxification, synthetic functions, and metabolic regulation are impaired to different degrees, and may result in major life-threatening complications such as hepatic encephalopathy, ascites, jaundice, cholestasis, bleeding and hepatorenal syndrome. Plasma exchange (PE) has been found useful in treating patients with fulminant hepatic failure by removing hepatic toxins and replacement of clotting factors, so PE treatment has temporary supportive effects on liver failure caused by severe viral hepatitis. in this study, our aim was to predict the prognosis of patients with severe hepatitis after PE treatment using the end-stage liver disease (MELD) scoring system. METHODS: Two hundred and twenty patients were randomly divided into PE and control groups, and the MELD score was calculated for each patient according to the original formula. The efficacy of PE was assessed by mortality or improvement in biochemical parameters and MELD score. RESULTS: The levels of total bilirubin and international normalised ratio (INR) in patients whose MELD scores were between 30 and 39 were lower than those before PE treatment, as those in patients whose MELD scores were 40 or higher. The mortality of patients in the PE group with MELD scores from 30 to 39 was 50.0%, while it was 83.3% in the control group (P0.05). CONCLUSIONS: PE treatment can decrease the serum total bilirubin level and INR and MELD score of patients with severe hepatitis and improve liver function. Compared with the control group, PE can significantly decrease the mortality of patients with MELD scores from 30 to 39, but has no effect in patients with MELD scores of 40 or higher.

关键词： severe hepatitis model for end-stage liver disease plasma exchange mortality

染料敏化太阳电池新型介孔碳对电极的制备及性能研究

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功能材料 2011年第1期42卷 14-16,20页

作者：王桂强禚淑萍山东理工大学化工学院山东淄博255049

以三嵌段共聚物F127为模板剂制备介孔碳,并用N2吸附和透射电子显微镜对介孔碳样品进行分析。所制备介孔碳材料的孔呈无序蠕虫状,平均孔径为6.8nm,比表面积为400m2/g。用介孔碳作为I-/I3-氧化还原反应的催化剂制备染料敏化太阳电池对电极... 详细信息

以三嵌段共聚物F127为模板剂制备介孔碳,并用N2吸附和透射电子显微镜对介孔碳样品进行分析。所制备介孔碳材料的孔呈无序蠕虫状,平均孔径为6.8nm,比表面积为400m2/g。用介孔碳作为I-/I3-氧化还原反应的催化剂制备染料敏化太阳电池对电极,用电化学阻抗谱对介孔碳电极的催化活性进行了分析。介孔碳电极对I-/I3-氧化还原反应具有很高的催化活性,电荷迁跃电阻为0.8Ω.cm2。用介孔碳电极作为对电极组装染料敏化太阳电池,电池的开路电压、短路电流密度及光电转换效率分别达到0.613V、15.5mA/cm2和6.18%。

关键词：介孔碳对电极染料敏化太阳电池

Severe liver injury induced by repeated use of hair dye

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Chinese Medical Journal 2009年第7期122卷 875-877页

作者： HOU Feng-qin LIN Xiao-hong YU Yan-yan wang Tai-ling wang gui-qiang Department of InFectious Diseases and the Center for LiverDiseases Peking University First Hospital Beijing 100034 China Department of Pathology Sino-Japan Friendly Hospital Beijing100029 China

Asignificant number of drugs has been proven, or at least suggested, to cause hepatotoxicity. Liver injury due to herbal medicines, chemicals or natural toxins also occur from household, occupational, or environmental exposure. However, liver toxicity due to hair dyes now is rarely recognized. Only in 2003, Tokumoto et al reported a case of hair dye-induced hepatitis, which presented a comparatively mild liver lesion. Here we described a case had more severe liver injury.

关键词： hair dyes liver injury

Hepatitis B core-related antigen reflects viral replication and protein production in chronic hepatitis B patients

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Chinese Medical Journal 2021年第10期134卷 1160-1167页

作者： Jun Li Zhao Wu gui-qiang wang Hong Zhao China HepB-Related Fibrosis Assessment Research Group Department of Infectious Disease Center for Liver DiseasePeking University First HospitalBeijing 100034China The Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases Zhejiang UniversityHangzhouZhejiang 310000China Department of Infectious Disease Peking University International HospitalBeijing 100034China 不详

Background:Hepatitis B core-related antigen(HBcrAg)is a promising disease-monitoring marker for chronic hepatitis B(CHB).We investigated correlations between HBcrAg with antiviral efficacy and virological and histological ***:One hundred and forty-five CHB patients from the mainland of China between August 2013 and September 2016 who underwent liver biopsy received entecavir therapy and had paired liver biopsy at 78 *** analyzed correlations between HBcrAg and virological and histological variables in hepatitis B e antigen(HBeAg)-positive and HBeAg-negative *** also explored the predictors of HBeAg loss after 78 weeks of antiviral *** correlation analysis and logistic forward stepwise regression were the main statistic ***:HBeAg-positive patients(n=93)had higher baseline HBcrAg(median 7.4 vs.5.3 log10 U/mL P<0.001)and greater HBcrAg declines(median 1.6 vs.0.9 log10 U/mL P=0.007)than HBeAg-negative patients after 78 weeks of *** baseline,HBcrAg correlated with hepatitis B virus(HBV)DNA in both HBeAg-positive(r=0.641,P<0.001)and-negative patients(r=0.616,P<0.001),with hepatitis B surface antigen(HBsAg)in HBeAg-positive patients(r=0.495,P<0.001),but not with anti-hepatitis B virus core antibody(anti-HBc).Weak correlations existed between HBcrAg,histology activity index(HAI;r=0.232,P=0.025),and Ishak fibrosis score(r=-0.292,P=0.005)in HBeAg-positive *** 78 weeks,significant correlations existed only between HBcrAg and anti-HBc in HBeAg-positive(r=-0.263,P=0.014)and HBeAg-negative patients(r=-0.291,P=0.045).Decreased HBcrAg significantly correlated with reduced HBV DNA(r=0.366,P=0.001;r=0.626,P<0.001)and HBsAg(r=0.526,P=0.001;r=0.289,P=0.044)in HBeAg-positive and-negative patients,respectively,and with reduced HAI in HBeAg-positive patients(r=0.329,P=0.001).Patients with HBeAg loss(n=29)showed a larger reduction in HBcrAg than those without(median 2.3 vs.1.3 log10 U/mL,P=0.001).In multivariate analysis,dec

关键词： Chronic hepatitis B Hepatitis B core-related antigen Hepatitis B e antigen Antiviral therapy

Clinical features of the overlap syndrome of autoimmune hepatitis and primary biliary cirrhosis: retrospective study

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Chinese Medical Journal 2006年第3期119卷 238-241页

作者： WU Chi-hong wang Qin-huan TIAN Geng-shan XU Xiao-yuan YU Yan-yan wang gui-qiang Department of Infectious Disease Peking University First HospitalBeijing 100034 China.

PBC-AIH overlap syndrome is an autoimmune liver disease between AIH （autoimmunehepatitis） and PBC （primary biliary cirrhosis）. To investigate the characteristic of the PBC-AIH ovedap syndrome, we have conducted a retrospective study of 12 diagnosed ovedap syndrome patients and compared them with typical PBC and AIH on the basis of clinical, biochemical, serological and histopathological findings.

关键词： primary biliary cirrhosi autoimmune hepatitis overlap syndrome clinical features

应用细胞毒药物或免疫抑制剂治疗时应重视预防乙型肝炎的发作

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中华内科杂志 2008年第10期47卷 796-797页

作者：王贵强北京大学第一医院感染疾病科肝病中心 100034

根据2006年全国人群乙型肝炎血清流行病学调查结果显示，我国1～59岁人群中HBsAg携带率已从1992年的9．75％降至7．18％，下降了26．36％。其中1～4岁人群HBsAg携带率最低，为0．96％；5～14岁人群为2．42％；15～59岁人群HBsAg携带率... 详细信息

根据2006年全国人群乙型肝炎血清流行病学调查结果显示，我国1～59岁人群中HBsAg携带率已从1992年的9．75％降至7．18％，下降了26．36％。其中1～4岁人群HBsAg携带率最低，为0．96％；5～14岁人群为2．42％；15～59岁人群HBsAg携带率最高，达8．57％。按目前HBsAg携带率推算，我国仍然有HBsAg携带者约9300万人。其中有部分为慢性乙型肝炎患者，大部分病情相对稳定。

关键词：慢性乙型肝炎患者免疫抑制剂细胞毒药物 HBsAg携带率 HBsAg携带者发作预防治疗

发热伴血小板减少综合征——由新型布尼亚病毒感染导致的一种新发传染病

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中华内科杂志 2011年第9期50卷 717-718页

作者：王贵强北京大学第一医院感染疾病科 100034

多种病原可导致“发热伴血小板减少”，包括病毒性出血热如肾综合征出血热、新疆出血热和登革热等，立克次体类疾病如斑疹伤寒、人埃里克体病及粒细胞无形体病等，以及严重细菌感染脓毒血症、DIC。

关键词：血小板减少综合征新发传染病病毒感染发热肾综合征出血热病毒性出血热严重细菌感染新疆出血热

应重视肾综合征出血热的特殊临床表现和早期诊断线索

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中华内科杂志 2006年第11期45卷 881-882页

作者：王贵强北京大学第一医院感染疾病科 100034

肾综合征出血热（HFRS）在我国又称流行性出血热，简称出血热，是由汉坦病毒引起的一种自然疫源性疾病，啮齿类动物特别是鼠类为其自然宿主和主要传染源。世界上有30多个国家发现HFRS，我国是HFRS流行最严重的国家，每年发病人数占世界... 详细信息

肾综合征出血热（HFRS）在我国又称流行性出血热，简称出血热，是由汉坦病毒引起的一种自然疫源性疾病，啮齿类动物特别是鼠类为其自然宿主和主要传染源。世界上有30多个国家发现HFRS，我国是HFRS流行最严重的国家，每年发病人数占世界汉坦病毒感染病例的90％以上。我国大陆除青海省与新疆维吾尔自治区外，各省、自治区、直辖市均有病例发生，台湾也有汉坦病毒感染病例报道。本病在我国主要分为姬鼠型和家鼠型两种类型，其中黑线姬鼠、黄颈姬鼠和大林姬鼠为姬鼠型出血热的主要宿主动物和传染源；褐家鼠为家鼠型出血热的主要宿主动物和传染源。目前我国存在姬鼠型、家鼠型和家鼠姬鼠混合型3种疫区，20世纪90年代以来，家鼠型疫区逐渐扩大，而且正在发生部分姬鼠型疫区向混合型疫区、混合型疫区向家鼠型疫区演变。

关键词：肾综合征出血热特殊临床表现诊断线索新疆维吾尔自治区家鼠型疫区汉坦病毒感染混合型疫区自然疫源性疾病