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Management of Acute Lower Extremity Thrombosis Associated with Bilateral Popliteal Aneurysms Using Combined Thrombolytic Therapy and Stent Graft Repair

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Chinese Medical Journal 2015年第4期128卷 564-566页

作者： Bao-Lei guo Wei-guo Fu Zhen-Yu Shi Li-Xin wang da-Qiao guo Department of Vascular Surgery Zhongshan Hospital Fudan University Institute of Vascular Surgery Shanghai 200032 China

To the Editor：This is a brief clinical report on different endovascular procedures in the treatment of popliteal artery aneurysms （PAAs）.A 75-year-old man presented at the vascular clinic with progressive left lower limb pain at rest associated with coolness,pain,and *** medical history was significant for hypertension and *** femoral and popliteal pulsations were only felt in the left ***,pallor,paresthesia,delayed capillary refilling,and color changes were noted in the left limb together with rest *** ultrasound was performed and an embolization （Rutherford Grade 2b） and bilateral PAAs were found,which on computed tomography angiogram （CTA） measured 62 mm and 82 mm with the maximum diameters in the right and left popliteal artery,*** was found in both aneurysm sacs [Figure 1 a and b].Thromboembolism from the left PAA could be seen in the distal *** potentially associated aneurysms were excluded by magnetic resonance *** erythrocyte sedimentation rate and C-reactive protein were moderately elevated,and thrombophilia profile was negative,and history for any orogenital ulcers was negative.

关键词： Popliteal Artery Aneurysms Endovascular Therapy Stent Grafts

A Mn-porphyrinic metal–organic framework immobilizing glucose oxidase for combined photodynamic/chemodynamic/starvation therapy

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Tungsten 2025年第1期7卷 183-194页

作者： Xin-Ran Sun Hao-Ming Yuan guo-da Zhang Chao wang Shu-Juan Sun Peng-Fei Shi Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers School of Chemistry and Chemical Engineering Linyi University

The combination of photodynamic therapy（PDT） and chemodynamic therapy（CDT） in tumor treatment has attracted considerable ***,tumor hypoxia and glutathione（GSH） overproduction in the tumor tissue restricted the progress of their ***,a Mn-porphyrinic metal-organic framework（Mn-TCPP） was constructed by the one-pot method and further used for immobilizing glucose oxidase（GOx） to obtain GOx@*** would rapidly exhaust endogenous glucose into hydrogen peroxide（H2O2） and gluconic acid,thus shutting off the energy supply of tumor cells for starvation ***-TCPP catalyzed H2O2to produce oxygen,regulating the hypoxic tumor microenvironment and in turn improving1O2generation under laser ***,Mn-TCPP can reduce reactive oxygen species consumption owing to the redox reaction between Mn3+and GSH,thus greatly enhancing ***,benefiting from GOx-mediated starvation therapy,Mn2+produced by Mn3+reduction can react with sufficient intracellular H2O2to generate ·OH with high cytotoxicity through a Fenton-like *** treatment by GOx@Mn-TCPP under laser irradiation in vitro,the cell viability of 4T1 and A549 tumor cells reached to 20%,reflecting GOx@Mn-TCPP could give full play to the advantages of PDT/CDT/starvation *** results in vivo demonstrated that GOx@Mn-TCPP mediated synergistic cascade therapy could significantly inhibit tumor growth and improve the therapeutic effect.

关键词： Chemodynamic therapy Immobilizing enzyme Metal–organic frameworks Photodynamic therapy Starvation therapy

Anomaly Detection of Controllable Electric Vehicles through Node Equation against Aggregation Attack

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Computers, Materials & Continua 2025年第1期82卷 427-442页

作者： Jing guo Ziying wang Yajuan guo Haitao Jiang State Grid Jiangsu Electric Power Co. Ltd.Research InstituteState Grid Corporation of ChinaNanjing211100China

The rapid proliferation of electric vehicle(EV)charging infrastructure introduces critical cybersecurity vulnerabilities to power grids *** study presents an innovative anomaly detection framework for EV charging stations,addressing the unique challenges posed by third-party aggregation *** approach integrates node equations-based on the parameter identification with a novel deep learning model,xDeepCIN,to detect abnormal data reporting indicative of aggregation *** employ a graph-theoretic approach to model EV charging networks and utilize Markov Chain Monte Carlo techniques for accurate parameter *** xDeepCIN model,incorporating a Compressed Interaction Network,has the ability to capture complex feature interactions in sparse,high-dimensional charging *** results on both proprietary and public datasets demonstrate significant improvements in anomaly detection performance,with F1-scores increasing by up to 32.3%for specific anomaly types compared to traditional methods,such as wide&deep and DeepFM(Factorization-Machine).Our framework exhibits robust scalability,effectively handling networks ranging from 8 to 85 charging ***,we achieve real-time monitoring capabilities,with parameter identification completing within seconds for networks up to 1000 *** research contributes to enhancing the security and reliability of renewable energy systems against evolving cyber threats,offering a comprehensive solution for safeguarding the rapidly expanding EV charging infrastructure.

关键词： Anomaly detection electric vehicle aggregation attack deep cross-network

非定常不可压N-S方程的最小二乘算子分裂有限元法数值求解

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计算力学学报 2014年第5期31卷 640-645页

作者：水庆象王大国西南科技大学环境与资源学院绵阳621010

采用最小二乘算子分裂有限元法求解非定常不可压N-S(Navier-Stokes)方程,即在每个时间层上采用算子分裂法将N-S方程分裂成扩散项和对流项,这样既能考虑对流占优特点又能顾及方程的扩散性质。扩散项是一个抛物型方程,时间离散采用向后差... 详细信息

采用最小二乘算子分裂有限元法求解非定常不可压N-S(Navier-Stokes)方程,即在每个时间层上采用算子分裂法将N-S方程分裂成扩散项和对流项,这样既能考虑对流占优特点又能顾及方程的扩散性质。扩散项是一个抛物型方程,时间离散采用向后差分格式,空间离散采用标准Galerkin有限元法。对流项的时间项采用后向差分格式,非线性部分用牛顿法进行线性化处理,再用最小二乘有限元法进行空间离散,得到对称正定的代数方程组系数矩阵。采用Re=1000的方腔流对该算法的有效性进行检验,表明其具有较高的精度,能够很好地捕捉流场中的涡结构。同时,对圆柱层流绕流进行了数值研究,通过流线图、压力场、阻力系数、升力系数及斯特劳哈数等结果的分析与对比,表明本文算法对于模拟圆柱层流绕流是准确和可靠的。

关键词：最小二乘算子分裂有限元法 N-S方程方腔流圆柱绕流

Effect of Nb-V microalloying on the hot deformation behavior of medium Mn steels

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 360-368页

作者： Yumeng wang Qinyi guo Bin Hu Haiwen Luo School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China

The influence of Nb-V microalloying on the hot deformation behavior and microstructures of medium Mn steel(MMS)was investigated by uniaxial hot compression *** establishing the constitutive equations for simulating the measured flow curves,we successfully constructed deformation activation energy(Q)maps and processing maps for identifying the region of flow *** concluded the following consequences of Nb-V alloying for MMS.(i)The critical strain increases and the increment diminishes with the increasing deformation temperature,suggesting that NbC precipitates more efficiently retard dynamic recrystallization(DRX)in MMS compared with solute Nb.(ii)The deformation activation energy of MMS is significantly increased and even higher than that of some reported high Mn steels,suggesting that its ability to retard DRX is greater than that of the high Mn content.(iii)The hot workability of MMS is improved by narrowing the hot processing window for the unstable flow stress,in which fine recrystallized and coarse unrecrystallized grains are present.

关键词： medium manganese steel niobium-vanadium microalloying flow behavior dynamic recrystallization hot workability

深部岩体中断续节理对巷道稳定性影响的数值试验

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辽宁工程技术大学学报（自然科学版） 2007年第4期26卷 481-484页

作者：张哲王大国洪林东北大学岩石破裂与失稳研究中心辽宁沈阳110004 大连大学材料破坏力学数值试验研究中心辽宁大连116622 辽宁工程技术大学安全科学与工程学院辽宁阜新123000

应用岩石破裂过程分析软件RFPA2D,通过对具有断续软弱结构面深部岩体中隧道的变形破坏特征、隧道周边关键部位的位移和应力变化进行了分析,对巷道在载荷作用下的声发射和位移特性进进行了探讨,着重研究了深部岩体中节理对巷道稳定性的... 详细信息

应用岩石破裂过程分析软件RFPA2D,通过对具有断续软弱结构面深部岩体中隧道的变形破坏特征、隧道周边关键部位的位移和应力变化进行了分析,对巷道在载荷作用下的声发射和位移特性进进行了探讨,着重研究了深部岩体中节理对巷道稳定性的影响。这对于进一步理解深部岩体中节理对巷道影响进而采取有效的加固措施等具有重要的理论和实践意义。

关键词：深部岩体断续节理巷道稳定性数值试验

改进的基于特征线的N-S方程算子分裂有限元法

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船舶力学 2016年第4期20卷 381-392页

作者：水庆象王大国沈连山西南科技大学环境与资源学院四川绵阳621010 大连大学信息工程学院辽宁大连116622

基于特征线的Navier-Stokes(N-S)方程算子分裂有限元法(CBOS有限元法)的核心是在每一个时间层上,采用算子分裂法将N-S方程的对流项和扩散项分开求解;对流项的求解过程借鉴了简单显式特征线时间离散,显式求解。该文在原CBOS有限元法基础... 详细信息

基于特征线的Navier-Stokes(N-S)方程算子分裂有限元法(CBOS有限元法)的核心是在每一个时间层上,采用算子分裂法将N-S方程的对流项和扩散项分开求解;对流项的求解过程借鉴了简单显式特征线时间离散,显式求解。该文在原CBOS有限元法基础上推导了一种更加精确的对流项显式离散方法。通过自编程序对方腔流进行数值模拟,表明该算法具有更高的计算精度。低雷诺数下圆柱绕流计算所得的阻力系数、升力系数、斯特劳哈数等与已有数据较为接近,表明该文中算法能较准确地模拟圆柱绕流的流场特性;最后,文中分析了Re=200时圆柱绕流在一个周期内所受升力变化与对应流场中压力和流线演化的关系。

关键词： N-S方程 CBOS有限元法方腔流圆柱绕流

三轴条件下岩石抗剪强度参数线性回归法的修正

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岩土力学 2022年第10期43卷 2689-2697页

作者：李斌王大国何治良王鹏西南科技大学环境与资源学院四川绵阳621010 西南石油大学土木工程与测绘学院四川成都610500

岩石三轴强度包络线通常为非线性,通过线性回归法(LRM)获得的抗剪强度参数对围压的变化具有很高的敏感性。为使LRM能够考虑围压对抗剪强度参数估计的影响,定义了岩石三轴强度围压效应系数,构造一个指数函数表示该系数与围压的关系,并将... 详细信息

岩石三轴强度包络线通常为非线性,通过线性回归法(LRM)获得的抗剪强度参数对围压的变化具有很高的敏感性。为使LRM能够考虑围压对抗剪强度参数估计的影响,定义了岩石三轴强度围压效应系数,构造一个指数函数表示该系数与围压的关系,并将其引入到LRM的修正中,提出考虑围压效应的线性回归分析法(CCPE-LRM)。同时,提出了CCPE-LRM的合理性检验方法,并定义了距离系数作为指标来表征抗剪强度参数估计值与参数实际值的差异。通过以公开发表文献中多种类型岩石的三轴强度数据为例进行验证分析,结果显示各种岩石的距离系数均较小,CCPE-LRM获得的抗剪强度包络线紧贴摩尔圆,且近似相切状态。表明通过CCPE-LRM获得的抗剪强度包络线在一定程度上可以代替理想抗剪强度包络线,该方法估计的抗剪强度参数与理论抗剪强度参数的一致性较高,证明CCPE-LRM具有较好的适用性。

关键词：岩石抗剪强度参数线性回归法围压效应岩石三轴强度抗剪强度包络线

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三维完全非线性波浪水槽的数值模拟(英文)

船舶力学 2010年第6期14卷 577-586页

作者：王大国邹志利刘霞大连大学材料破坏力学数值试验研究中心辽宁大连116622 大连理工大学海岸和近海工程国家重点实验室辽宁大连116024 香港大学土木工程系香港999077

用有限元求解拉普拉斯方程,采用满足完全非线性自由表面条件的半拉格朗日法追踪流体自由表面,离散单元采用20节点的六面体二次等参数单元,建立了三维完全非线性数值波浪水槽。把数值计算结果与水面初始升高产生箱体内流体运动解析解和... 详细信息

用有限元求解拉普拉斯方程,采用满足完全非线性自由表面条件的半拉格朗日法追踪流体自由表面,离散单元采用20节点的六面体二次等参数单元,建立了三维完全非线性数值波浪水槽。把数值计算结果与水面初始升高产生箱体内流体运动解析解和二阶斯托克波理论解进行了对比,结果表明该模型是稳定的、守恒的,能精确模拟非线性波浪的产生和传播,为今后研究非线性波浪对船舶等非规则物体的作用提供了参考。

关键词：三维波浪水槽完全非线性拉普拉斯方程有限元