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Percutaneous transluminal renal angioplasty with stent is effective for blood pressure control and renal function improvement in atherosclerotic renal artery stenosis patients

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Chinese Medical Journal 2012年第8期125卷 1363-1368页

作者： LIAO Chuan-jun YANG Bao-zhong wang zhong-gao Department of Vascular Surgery Chao-Yang Hospital CapitalMedical University Beijing 100020 China Department of Vascular Surgery Xuanwu Hospital Institute ofVascular Surgery Capital Medical University Beijing 100053China

Background Percutaneous transluminal renal angioplasty with stent is an effective procedure for atherosclerotic renal artery stenosis. However, the decision to perform this procedure has recently raised considerable debate. The aim of this study was to assess the effects of percutaneous transluminal renal angioplasty with stent in atherosclerotic renal artery stenosis patients, especially as it relates to blood pressure control and renal function improvement. Methods A retrospective analysis was made of the clinical data from 125 atherosclerotic renal artery stenosis patients who underwent percutaneous transluminal renal angioplasty from July 2004 to June 2008 in the Department of Vascular Surgery of Beijing Chaoyang Hospital. We compared blood pressure, number of oral antihypertensive medications, and renal function changes pre and post-procedure at 24 months follow-up. Results A total of 125 atherosclerotic renal artery stenosis patients underwent percutaneous transluminal renal angioplasty and 143 stents were placed. At 24 months follow-up, both systolic and diastolic blood pressure and the number of oral antihypertensive medications were significantly reduced （P 〈0.05）. Overall, the estimated glomerular filtration rate did not change significantly （P〉0.05）; however, a significant increase in estimated glomerular filtration rate was observed in the subgroup of patients with a lower baseline estimated glomerular filtration rate and in the subgroup of patients with bilateral renal artery stenosis （P 〈0.05）. Conclusion Percutaneous transluminal renal angioplasty patients, providing a significant improvement in blood antihypertensive medications. s a safe procedure for atherosclerotic renal artery stenosis pressure control and reduction in the number of oral

关键词： renal artery stenosis renal angioplasty stent renovascular hypertension, glomerular filtration rate

Long-term results of endovascular therapy for proximal subclavian arterial obstructive lesions

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Chinese Medical Journal 2010年第1期123卷 45-50页

作者： wang Ke-qin wang zhong-gao YANG Bao-zhong YUAN Chao ZHANG wang-de YUAN Biao XING Tong SONG Sheng-han LI Tan LIAO Chuan-jun ZHANG Yang Department of Vascular Surgery Chaoyang Hospital CapitalMedical University Beijing 100020 China Department of Vascular Surgery Xuanwu Hospital and Institute ofVascular Surgery Capital Medical University Beijing 100053China

Background Endovascular therapy is a treatment option for localized occlusion of the subclavian artery. In this report the long-term experience with 59 patients is presented. Methods Between June 1998 and September 2008, we used endovascular therapy to treat 61 subclavian arterial obstructive lesions in 59 patients （46 males and 13 females, 34-82 years of age with a mean age （61.9~11.0） years）. Twenty patients （34%） had clinical symptoms due to vertebrobasilar insufficiency, 26 （44%） had disabling arm ischemia, and 13 （22%） had both symptoms. We performed all procedures under local anesthesia. The approaches were from the femoral artery （n=47）, brachial artery （n=-1, involving bilateral subclavian disease） or both （n=11）. Sixty stents were implanted. All patients were followed-up at 1,3, 6, and 12 months post-procedure, and annually thereafter. Results We achieved technical success in 58 （95.1%） arteries, all of which were stented. There were three technical failures; two were due to the inability to cross over an occlusion, necessitating the switch to an axillo-axillary bypass, and the third was due to shock after digital subtraction angiography and prior to stenting. Arterial stenosis pre- and post-stenting was （83.6±10.8）% and （2.5±12.5）% （P 〈0.01）. Clinical success was achieved in 55 of the 59 patients （93.4%）. Of the four clinical failures, three were technical and the remaining patient had a stent thrombosis. Systolic blood pressure difference between the two brachial arteries was （44.7±18.5） vs. （2.2±3.9） mmHg （P 〈0.01）. Primary patency was 98% at 12 months, 93% at 24 months, and 82% at 5 years. Five patients were lost to follow-up by 12 months post-stenting. Significant recurrent obstruction developed in five patients with resumption of clinical symptoms. The overall survival rate was 98.2% at 12 months, 89.5% at 24 months, and 84.5% at 5 years. Conclusions Endovascular therapy for proximal subclavian arterial obstructive lesions is effective and successful.

关键词： subclavian artery subclavian steal syndrome arterial occlusive diseases stents vertebrobasilar insufficiency

RECOGNITION AND MANAGEMENT OF BUDD-CHIARI SYNDROME: EXPERIENCE WITH 143 PATIENTS

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中华医学杂志(英文版) 1989年第5期102卷 346-346页

作者： wang zhong-gao Department of Vascular Surgery Beijing Heart Lung Blood Vessel Medical Center Anzhen Hospital Beijing

Of 143 patients with Budd-Chiari syndrome treated from December 1982 to August 1988, 100 had intractable ascites, 78 had esophageal varices and 39 had upper gastrointestinal bleeding. In these patients, 49 had membranous obstruction, 134 had occlusive lesions of the inferior vena cava (IVC) above the confluence of the hepatic veins including 50 membranous obstructions, and 9 had occlusion of the hepatic veins. According to the location and extent of lesions, we classified this disease into eight categories; the severity of the disease and corresponding operative risk were used to divide the disease into four grades. One hundred and four patients (73%) were operated upon. There was no death in Stage I and II patients, but in Stage III and IV patients the mortality was 9% and 21% respectively. The overall operative mortality was 9.6%. Follow-up for 1 to 66 months revealed that 73% (76/104) had good results except 4 who died from other causes. Among 39 patients receiving conservative treatment, 13 (33.3%) died of late complications. They all belonged to Stage IV patients. We conclude that the earlier the treatment the better the results, and the operative procedure must be tailored to the etiology and underlying pathology.

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Sono-assembly of folate-decorated curcumins/alginate core-shell microcomplex and its targeted delivery and pH/reduction dual-triggered release

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Particuology 2024年第1期84卷 168-177页

作者： Qingye Meng Shuangling zhong Jingfei wang Zhenqian Zhang Yan gao Xuejun Cui College of Chemistry Jilin University Changchun130012China College of Resources and Environment Jilin Agricultural University Changchun130118China State Key Laboratory of Supramolecular Structure and Materials Jilin UniversityChangchun130012China Weihai Institute for Bionics-Jlin University Weihai264400China

In this study,sodium alginate(SA),a non-toxic natural polysaccharide with good biocompatibility and biodegradability,was developed for targeted delivery of curcumin(CUR)in tumor *** strategy is to sulfhydrylate the folic acid(FA)modified SA,and the CUR dissolved in ethyl acetate(EAC)phase is coated in microcapsules by a quick,efficient and environment-friendly sonochemical *** EAC in the microcapsule core is volatile,which can be recycled and reused to reduce *** prepared mi-crocapsules(FA-RSMCs@CUR)exhibited similar toxicity to free curcumin in anti-tumour evaluation in ***-RSMCs@CUR also exhibited effective antibacterial properties in the antibacterial evaluation in *** is expected to become a low-cost tumor targeting vector in the future,and has the potential to be promoted in clinical application.

关键词： Reductive-responsive Sodium alginate Microcapsule Targeted delivery Sonochemical

Diagnosis and treatment of superior mesenteric artery compression syndrome complicated with gastroesophageal reflux disease

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Chinese Medical Journal 2021年第11期134卷 1382-1384页

作者： Rui Zhang Zhi-Tong Li Xin-Wei Han Li-Dan Liang zhong-gao wang Feng Ji Department of Respiratory and Critical Care Medicine The First Affiliated Hospital of Zhengzhou UniversityZhengzhou UniversityZhengzhouHenan 450052China Department of Intervention The First Affiliated Hospital of Zhengzhou UniversityZhengzhou UniversityZhengzhouHenan 450052China Department of Radiology The First Affiliated Hospital of Zhengzhou UniversityZhengzhou UniversityZhengzhouHenan 450052China.

To the Editor:Superior mesenteric artery compression syndrome(SMAS)is a relatively rare disease caused by the narrowing of the angle between the abdominal aorta and the superior mesenteric artery,thus compressing the third segment of the duodenum.[1]SMAS is mainly characterized by post-prandial epigastric pain,abdominal distension,nausea,vomiting,anorexia,and weight *** approaches,including nutritional support,are effective,although approximately 75%of patients still require surgical treatment.[2]

关键词： artery nausea vomiting

Advances in controlled-release fertilizer encapsulated by organic-inorganic composite membranes

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Particuology 2024年第1期84卷 236-248页

作者： Xueping wang Yongyan Yang Shuangling zhong Qingye Meng Yiwei Li Jia wang Yan gao Xuejun Cui College of Chemistry Jilin UniversityChangchun130012China College of Resources and Environment Jilin Agricultural UniversityChangchun130118China State Key Laboratory of Supramolecular Structure and Materials Jilin UniversityChangchun130012China Weihai Institute for Bionics-Jilin University Weihai264400China

Heavy use of conventional fertilizers can lead to negative environmental ***-release fertilizers(CRFs)can effectively reduce the amounts of fertilizers used,improve the availability of fer-tilizers,and which is conducive to the protection of the ecological environment and sustainable devel-opment of ***,it is imperative to develop and use CRFs as an alternative to traditional *** review aims to present the classification,raw material composition,benefits,release process,release mode,and manufacturing methods of fertilizers coated with organic-inorganic com-posite membranes(OICMs)in order to provide an overall update and summarize CRFs encapsulated by OICMs and provide an insight for future trends in the field of *** is expected that utilizing CRFs encapsulated by OICMs and their characteristics for agricultural applications can provide innovative ideas and suggestions for developing novel CRFs suitable for modern and sustainable agriculture.

关键词： Controlled-release fertilizers Organic-inorganic composite membranes Surface treatments

Surgical treatment of brachiocephalic vessel involvement in Takayasu＇s arteritis

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Chinese Medical Journal 2010年第9期123卷 1122-1126页

作者： WU Xin DUAN Hong-yong GU Yong-quan LI Jian-xin CHEN Bing wang zhong-gao ZHANG Jian Department of Vascular Surgery Xuanwu HospitalCapital Medical UniversityBeijing 100053China

Background Takayasu＇s arteritis （TA） is a chronic idiopathic inflammatory disease that affects large and medium size arteries. The brachiocephalic trunk is the most frequently involved site in TA, and multi-vessel lesions are common. Surgical treatment includes vessel reconstruction surgery and percutaneous transluminal angioplasty （PTA）. Herein, we report our preliminary experience with surgical treatment of cerebral ischemia caused by cervical arterial lesions due to *** From January 2000 to December 2007, 38 patients with cerebral ischemia caused by cervical arterial occlusive lesions due to TA were treated surgically. There were three males and 35 females, with an age range of 15-42 years （mean 26.5 years）. All patients had operative repairs undertaken. Twenty eight patients received bypass operation and 10 patients received percutaneous transluminal angioplasty. One case with coronary stenosis received coronary artery bypass simultaneously. Patients were followed up for 11 months to eight *** There were no peri-operative deaths in cerebrovascular reconstruction patients. Symptoms of cerebral ischemia were improved or cured in 25 of 38 patients. There was a low incidence of cerebral reperfusion syndrome. Two patients died at five and seven years after surgery due to heart failure. Another 8 patients （20%） required further surgery for stenosis （5 patients） or anastomotic aneurysms （3 patients）. Percutaneous transluminal angioplasty was performed successfully for treatment of aortic and renal lesions. Repeated angioplasty for revascularization was performed in six PTA cases with restenosis after 5-24 *** When cerebral perfusion has potential to be affected by TA, a definitive corrective procedure is advised when the patient is relatively stable. Although the recurrence rate is very high, percutaneous transluminal angioplasty is the first choice procedure. Bypass operation is optimal for brachiocephalic-vessel involvement in TA. Cere

关键词： Takayasu's arteritis brain ischemia brachiocephalic trunk surgical procedures operative reperfusion syndrome

Animal study for airway inflammation triggered by gastroesophageal reflux

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Chinese Medical Journal 2009年第22期122卷 2775-2778页

作者： LAI Yun-gang wang zhong-gao JI Feng WU Ji-min CHEN Xiu LI Zhen DONG Shu-kui Department of Vascular Surgery Xuanwu Hospital Capital Medical University Beijing 100053 China Center for GERD the Second Artillery General Hospipital Beijing 100088 China

Background Gastroesophageal reflux disease with extra-esophageal symptoms, especially those with respiratory distress was attracting more and more attention. The related mechanisms were still in controversy. The purpose of the work was to explore airway inflammation triggered by gastroesophageal reflux. Methods Sixteen Sprague-Dawley rats were used as study group and 9 as control. In the study group, a plastic extender with a trumpet-shaped distal end was inserted into the lower esophagus to dilate the cardia, the pylorus was ligated. One ml of 0.1 mol/L hydrochloric acid was injected into the stomach. While a simple laparotomy was performed for control animals. All animals from two groups were sacrificed 24 hours after operation. Then tracheotomy was carried and the bronchoalveolar lavage fluid was collected in all animals. Cells in the fluid were counted and levels of interleukin （IL）-5, -6, -8 in it were measured. Results Compared with control group, the study group presented a neutrophil pattern of airway inflammation and an elevated concentration of IL-5, -6, -8 with no significant difference regarding eosinophil count. Conclusion The gastroesophageal reflux-triggered airway inflammation is characterized by a neutrophilic airway inflammation which differed from that caused by asthma, and enhanced levels of IL-5, -6 and -8, which are similar to that caused by asthma.

关键词： gastroesophageal reflux inflammation interleukins

High-temperature wetting behavior between slag and refractory

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Journal of Iron and Steel Research International 2024年第6期31卷 1304-1319页

作者： Yong-xin wang Ya-ge Li Ya-bo gao zhong Huang Hai-jun Zhang The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina

Slag corrosion is one of the main factors of the damage of refractory,and its primary manifestations involve the melting of refractory in slag and the slag penetration into refractory,both of which are highly related to the wetting behavior between slag and *** high-temperature wettability could be characterized by parameters including the surface tension,adhesion work,and spreading coefficient of the slag on refractory surface,and it could be suppressed by altering the slag/refractory interface,thus resulting in an improved anti-corrosion *** this,the key knowledges of the slag corrosion,theory of wetting behavior and test of high-temperature contact angle were firstly ***,the major factors influencing the high-temperature slag wetting behavior were discussed based on the aspects of slag composition,refractory composition,and surface ***,the future research direction was proposed in this field.

关键词： High-temperature wetting Refractory Slag corrosion Surface tension