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Joint use of time-domain and windowed method for design of modulated DFT filter banks

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The Journal of China Universities of Posts and Telecommunications 2013年第5期20卷 91-96页

作者： ZHUANG Ling JI Xiang SHAO Kai wang guang-yu Chongqing Key Laboratory of Mobile Communications Technology Chongqing University of Posts and Telecommunications

A novel and efficient technique to design modulated discrete Fourier transform （DFT） filter banks is introduced in this paper. The proposed method first relaxes the limits that the synthesis filters are the time-reversed version of the analysis filters and then adopts the time domain formula of the perfect reconstruction property as the solution to design the synthesis filters. The prototype filter in analysis filter banks is designed based on Fourier-Kaiser window approach. Simulation results show that the designed filter banks approximately satisfy the perfect reconstruction with controllable reconstruction errors.

关键词： time-domain formula DFT filter banks prototype filter design filter banks design

Do Cation-π Interactions Exist in Bacteriorhodopsin?

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Chinese Physics Letters 2001年第2期18卷 298-300页

作者： HU Kun-Sheng wang guang-yu HE Jin-An Institute of Biophysics Chinese Academy of SciencesBeijing 100101

Metal ions are essential to the structure and physiological functions of *** evidence suggests the existence of specific cation binding to the negatively charged groups of Asp85 and Asp212 via an electrostatic ***,only using electrostatic force is not enough to explain the role of the metal cations because the carboxylate of Asp85 is well known to be protonated in the M *** the presence of some aromatic amino acid residues in the vicinity of the retinal pocket,the existence of cation-πinteractions between the metal cation and aromatic amino acid residues is ***,introduction of this kind of interaction is conducive to understanding the effects of the metal cations and aromatic amino acid residues inside the protein on the structural stability and proton pumping of bacteriorhodopsin.

关键词： interaction residues electrostatic

Influences of H^(+)Implantation on the Boron-Doped Synthesized by Chemical Vapor Deposition Diamond Films

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Chinese Physics Letters 2000年第9期17卷 686-688页

作者： wang Shuang-Bao ZHU Pei-Ran wang yu-guang FENG Ke-An Institute of Physics Chinese Academy of SciencesBeijing 100080

Diamond films(DF)were preliminarily B doped in situ during chemical vapor ***,the films were implanted with 120keV H^(+)to dose of 5×10^(14)~5×10^(16)cm^(-2).After the implantation,the B doped DF become insulating and Raman measurements indicate that the implantation has amorphous carbon and graphite *** is known that the formation of H-B pairs plays an important pole in property ***,for larger dose cases,the electrical resistance of DF is influenced by radiation damage and/or non-diamond *** addition to them,annealing makes the specimens conducting *** phenomenon maybe has potential for application in designing DF device.

关键词： Diamond implantation conducting

Evaluating the efficacy of an attenuated Streptococcus equi ssp. zooepidemicus vaccine produced by multi-gene deletion in pathogenicity island SeseCisland_4

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Journal of Integrative Agriculture 2019年第5期18卷 1093-1102页

作者： MA Fang wang guang-yu ZHOU Hong MA Zhe LIN Hui-xing FAN Hong-jie MOE Joint International Research Laboratory of Animal Health and Food Safety College of Veterinary Medicine Nanjing Agricultural University National Center of Meat Quality and Safety Control Nanjing Agricultural University Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses Yangzhou University

Streptococcus equi ssp. zooepidemicus(SEZ) is a pathogen associated with a wild range of animal species. Frequent outbreaks have occurred in recent years in pigs, horses, goats and dogs which is liable to infect humans. There is a lack of efficient vaccines against this disease and the occurrence of antibiotic resistance may render drug therapies ineffective. In this study, gene deletion mutant(ΔSEZ) in pathogenicity islands SeseCisland_4 was constructed. The mutant ΔSEZ had a 52-fold decrease in 50% lethal dose(LD_(50)) and had less capacity to adhere epithelial cells. Importantly, immunization of mice with attenuated vaccine ΔSEZ at the dose of 10~2 colony-forming units(CFU) mL^(–1) elicited a significant humoral antibody response, with an antibody titer of 1:12 800. Therefore, 10~2 CFU mL^(–1) might be used as the appropriate immune dose for the attenuated vaccine ΔSEZ, which provided mice with efficient protection against virulent SEZ. In addition, the hyperimmune sera against 10~2 CFU m L–1 attenuated vaccine ΔSEZ could confer significant protection against virulent SEZ infection in the passive immunization experiment and exhibited efficient bactericidal activity in the whole blood assay. Meanwhile, no viable bacteria was detected in blood when mice were immunized with ΔSEZ at the dose of 10~2 CFU mL^(–1) via hypodermic injection. Thereafter, the mutant ΔSEZ at the dose of 10~2 CFU mL^(–1) could confer significant protection in mice and had less negative effects on host, which could be an effective attenuated vaccine candidate for the prevention of SEZ.

关键词： Streptococcus equi ssp.zooepidemicus zoonosis attenuated vaccine immune dose

Tetramethylpyrazine protects lymphocytes from radiationinduced apoptosis through nuclear factor-κB

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Chinese Journal of Natural Medicines 2014年第10期12卷 730-737页

作者： wang Xiao-Yan MA Zeng-Chun wang yu-guang TAN Hong-Ling XIAO Cheng-Rong LIANG Qian-De TANG Xiang-Lin CHENG yu GAO yue Institute of Radiation Medicine Academy of Military Medical Science Chongqing Maternal and Child Health-Care Hospital

AIM: Radiation induces an important apoptosis response in irradiated organs. The objective of this study was to investigate the radioprotective effect of tetramethylpyrazine(TMP) on irradiated lymphocytes and discover the possible mechanism of protection. METHOD: Lymphocytes were pretreated for 12 h with TMP(25-200 μmol·L-1) and then exposed to 4 Gy radiation. Cell apoptosis and the signaling pathway were analyzed. RESULTS: Irradiation increased cell death, DNA fragmentation, activated caspase activation and cytochrome c translocation, downregulated B-cell lymphoma 2(Bcl-2) and up-regulated Bcl-2-associated X protein(Bax). Pretreated with TMP significantly reversed this tendency. Several anti-apoptotic characteristics of TMP, including the ability to increase cell viability, inhibit caspase-9 activation, and upregulate Bcl-2 and down-regulate Bax in 4Gy-irradiated lymphocytes were determined. Signal pathway analysis showed TMP could translate nuclear factor-κB(NF-κB) from cytosol into the nucleus. CONCLUSION: The results suggest that TMP had a radioprotective effect through the NF-κB pathway to inhibit apoptosis, and it may be an effective candidate for treating radiation diseases associated with cell apoptosis.

关键词： Tetramethylpyrazine Radioprotection NF-κB Apoptosis

Predictors of atrial fibrillation after coronary artery bypass graft： a meta-analysis

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Journal of Geriatric Cardiology 2009年第3期6卷 162-167页

作者： Liang Yin Zhi-Nong wang Yi-Feng wang Wen-Tao wang guang-yu Ji Xin-Wei Yang Zhi-yun Xu Department of Cardiothoracic Surgery Changhai Hospital Second Military Medical University of PLA Shanghai 200433 China

Objectives Postoperative atrial fibrillation （AF） has been associated with less favorable outcomes in patients undergoing coronary artery bypass graft surgery （CABG） and may result in increased post-operative morbidity and mortality. A systematic review and meta-analysis of published studies was conducted to examine the risk factors of occurrence AF after CABG. Methods Using the Medline database, the Cochrane clinical trials database and online clinical trial databases, we reviewed all randomized controlled trials （RCTs） and observational studies examining the risk factors of occurrence of AF after CABG. We searched for literature published April 2009 or earlier. Results Our review identified 8 studies （observational studies）, involving 14548 patients, that examined the risk factors of occurrence of AF after CABG. Although studies provide conflicting results, the overall outcomes suggests that advanced age, previous hypertension, numbers of bridge vessels may increase the occurrence of AF after CABG, while no significant difference of diabetes, preoperative myocardial infarction, and preoperative medication of 13 -Blocker have been observed between the AF patients and no-AF patiens. Conclusions Patients with advanced age, previous hypertension and more numbers of bridge vessels had higher risk for the occurrence of AF after CABG, and perioperative medication and care must be intensified to decrease the postoperative occurrence ofAF（J Geriatr Cardio12009; 6：162-167）.

关键词： atrial fibrillation coronary artery bypass graft postoperative meta-analysis predictors

Effect of Surface Hydrogen Coverage on Field Emission Properties of DiamondFilms Investigated by High-Resolution Electron Energy Loss Spectroscopy

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Chinese Physics Letters 2000年第4期17卷 294-295页

作者： wang yu-guang GU Chang-Zhi JIN Zeng-Sun XIONG Yan-yun LIN Zhang-Da FENG Ke-An State Key Laboratory of Surface Physics Institute of PhysicsChinese Academy of SciencesBeijing 100080 State Key Laboratory of Superhard Materials Jilin UniversityChangchun 130023

The influence of surface hydrogen coverage on the electron field emission of diamond films was investigated by high-resolution electron energy loss *** was found that hydrogen plasma treatment increased the surface hydrogen coverage while annealing caused hydrogen desorption and induced surface *** electron emission measurements manifested that increase of surface hydrogen coverage could improve the field emission properties,due to the decrease of electron affinity of the *** hy hvdrogen adsorption.

关键词： spectroscopy. surface Diamond

Theoretical Researches on the Self-assembly System of Molecularly Imprinted Polymers Formed via Phenobarbital and Acrylamide

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Chinese Journal of Structural Chemistry 2019年第7期38卷 1069-1078页

作者： wang guang-yu LIU Jun-Bo TANG Shan-Shan CHANG Hai-Bo JIN Rui-Fa College of Food Science and Engineering Jilin Agricultural University Changchun 130118China College of Resources and Environment Jilin Agricultural University Changchun 130118 China College of Life Science Jilin Agricultural University Changchun 130118 China College of Chemistry and Chemical Engineering Chifeng University Chifeng 024000 China

For preparing the phenobarbital(PHN) molecularly imprinted polymers(MIPs) with higher adsorption and selectivity properties, we used the M062 X/6-31 g(d,p) method of density functional theory to predict the various properties of PHN-MIPs. Here PHN is as the imprinted molecule and acrylamide(AM) as the functional monomer. The ethylene glycol dimethacrylate,trimethylolpropane trimethacrylate, divinyl benzene, and pentaerythritol trimethacrylate are as the cross-linking agents, respectively. The acetonitrile, chloroform, toluene, and tetrahydrofuran are used as the solvents, respectively. The configurations of the molecular imprinting self-assembly system for PHN and AM have been simulated to study their bonding sites, binding energy, amount of hydrogen bond, and interaction mechanism. The essence of imprinting interaction for PHN and AM has been revealed by the atomic in the molecule theory. Meanwhile, the analogues of PHN were used to discuss the selectivity property of the stable PHN-AM complex. The results show that the PHN interacts with AM through hydrogen bonds. When the imprinting molar ratio of PHN-AM is1:6 and the THF is as the solvent, the amount of their hydrogen bonds is the most, the binding energy is the lowest, and their configuration is the most stable. In comparison with the other cross-linking agents(EGDMA, TRIM, and DVB), the PETA is more suitable for PHN-MIPs. The selective property of PHN-MIP to PHN is excellent when PHN and DMBA exist at the same time.

关键词： PHN AM molecularly imprinted polymers computational simulation

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损伤控制性手术治疗严重肝外伤的临床效果

中国实用医药 2016年第12期11卷 23-24页

作者：王宇光内蒙古乌兰浩特市人民医院普外科 137400

目的探讨分析损伤控制性手术治疗严重肝外伤的临床效果。方法 28例严重肝外伤患者均采用损伤控制性手术治疗,观察分析其治疗效果。结果经治疗,25例患者治愈,占89.3%,3例死亡,占10.7%。术后有3例患者出现胆瘘,2例出现感染,经对症处理均... 详细信息

目的探讨分析损伤控制性手术治疗严重肝外伤的临床效果。方法 28例严重肝外伤患者均采用损伤控制性手术治疗,观察分析其治疗效果。结果经治疗,25例患者治愈,占89.3%,3例死亡,占10.7%。术后有3例患者出现胆瘘,2例出现感染,经对症处理均治愈。结论采用损伤控制性手术治疗严重肝外伤患者,根据患者损伤情况分次实施手术,效果显著。

关键词：损伤控制性手术严重肝外伤临床效果