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Transesophageal echocardiography guided cannulation for peripheral cardiopulmonary bypass during robotic cardiac surgery

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Chinese Medical Journal 2012年第18期125卷 3236-3239页

作者： wang yao gao chang-qing wang gang wang jia-li Cardiovascular Surgery Institute and Department ofCardiovascular Surgery Chinese People's Liberation ArmyGeneral HospitalChina Beiiing 100853

Background Minimally invasive cardiac surgery and closed chest cardiopulmonary bypass （CPB） techniques continue to evolve. Previous reports have demonstrated the benefits of fluoroscopy guided cannulation for endovascular CPB during port access cardiac surgery. However, few data are available on the role of transesophageal echocardiography （TEE） guided cannulation for peripheral CPB during robotic cardiac surgery. The purpose of this study was to evaluate TEE guided cannulation for peripheral CPB during robotic cardiac surgery. Methods We performed a retrospective analysis of intraoperative data of 129 consecutive patients underwent robotic cardiac surgical procedures requiring peripheral CPB from September 2007 to August 2011, which was established using femoral arterial inflow and kinetic venous drainage by way of the femoral vein and right internal jugular vein and a transthoracic aortic cross clamp. TEE was used to guide cannulation of the inferior vena cava （IVC）, superior vena cava （SVC）, and ascending aorta （AAO）. The success rate and the complication rate of TEE guided cannulation for peripheral CPB were evaluated and compared with the results of fluoroscopy guided cannulation in a historical control group. Results One hundred and twenty-nine consecutive patients underwent robotic cardiac surgical procedures requiring peripheral CPB. There were 67 female （51.9%） and 62 male （48.1%） patients, ranging in age from 13 to 70 years （mean （43.94 ± 13.82） years） and body surface area 1.32 to 2.39 m2 （mean （1.71± 0.20） m2）. Some 61 （47.3%） patients underwent mitral valve repair, 27 （20.9%） mitral valve replacement, 27 （20.9%） left atrial myxoma removal, and 14 （10.9%） ventricular septal defect repair. Of the 129 patients, TEE guided cannulation of the IVC or SVC was successful in all patients （100%）, and no puncture related complications occurred in all patients. Of the 129 patients, successful cannulation of the AAO was achieved in all patients （100%）, and aortic pe

关键词： transesophageal echocardiography cardiopulmonary bypass," robotic cardiac surgery

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Ultrasound-guided cannulation of the internal jugular vein in robotic cardiac surgery

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Chinese Medical Journal 2013年第13期126卷 2414-2417页

作者： wang yao wang gang gao chang-qing Department of Cardiovascular Surgery Chinese People's LiberationArmy General Hospital Beijing 100853 China (Wang Y Wang Gand Gao CQ)

Background Robotic assisted minimally invasive cardiac sugery is a new technique that uses small port sites and peripheral vessel cannulation for cardiopulmonary bypass （CPB） has been used. The right internal jugular vein （IJV） is commonly used for intraoperative venous access to the central circulation and identified with an external landmark. Previous studies have demonstrated the superiority of ultrasound guidance over external landmark technique in anaesthetic and intensive care settings. The aim of the present study was to delineate the utility of ultrasound-guided cannulation of the IJV during establishment of peripheral CPB in robotic cardiac surgery. Methods We prospectively studied 296 adult patients undergoing ultrasound-guided right IJV cannulation during establishment of peripheral CPB in robotic cardiac surgery at our institute from January 2007 to October 2012 （ultrasound group）. The success rate, the first attempt success rate, access time and the complication rate of ultrasound-guided method were compared with the landmark-guided method used for 302 historical control patients （landmark group）. Results In the ultrasound group, 296 consecutive adult patients underwent ultrasound-guided right IJV cannulation during establishment of peripheral CPB in robotic cardiac surgery. In the landmark group, 302 patients underwent right IJV cannulation using the landmark-guided technique. The success rate and the first attempt success rate in the ultrasound group were significantly higher than that in the landmark group （100% vs. 88.1%, P 〈0.000 and 98.6% vs. 38.4%, P 〈0.000）. Average access time in the ultrasound group was shorter than that in the landmark group （（6.3＋13.6） seconds; interquartile range （4-62） seconds vs. （44.5＋129.5） seconds; interquartile range （5-986） seconds）. The complication rate in the ultrasound group was significantly lower than that in the landmark group （0.3% vs. 8.3%, P 〈0.000）. Conclusion Compared with the landmark-guided approach, ul

关键词： ultrasonography interventional central venous," minimally invasive surgical procedures robotic cardiac surgery, cardiopuImonary bypass

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Growth,Defects and Non-critical Phase Matching of Nb Doped KTP Crystals

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Chinese Physics Letters 1996年第3期13卷 203-206页

作者： WEI Jing-qian wang Ji-yang liU yao-gang wang chang-qing SHAO Zong-shu GUAN qing-cai jiaNG Min-hua Institute of Crystal Materials Shandong UniversityJi'nan 250100

A series of Nb doped KTP crystals are grown with seed Aux method and Hux pulling *** results of our investigation on growth,morphology defects of the crystals are reported in this *** obtained the relationship between Nb contents and second-harmonic generation angles of the *** phase matching has been realized by 4%Nb doped KTP crystal for Nd:YAG laser 1.06μm output.

关键词： Nd:YAG Crystal Matching

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Characteristics of life-cycle carbon dioxide emissions of arterial highway maintenance and the influencing factors

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Advances in Climate change Research 2024年第4期15卷 751-765页

作者： yao wang Yuan-qing wang Shu-Juan JI Si-jia SUN Shu-Hong MA Ya-Nan gao Key Laboratory of Transport Industry of Management Control and Cycle Repair Technology for Traffic Network Facilities in Ecological Security Barrier Area Chang'an UniversityXi'an 710064China Guangzhou Aids to Navigation Office Southem Navigation Service CenterMaritime Safety AdministrationGuangzhou 51000China

With the focus of highway development transitioning from construction to maintenance,a comprehensive understanding of the characteristics and influencing factors of carbon dioxide(CO_(2))emissions from highway maintenance activities is crucial for formulating effective strategies to promote the low-carbon development of road ***,the quantitative relationships between CO_(2) emissions from highway maintenance schemes and factors such as pavement deterioration,traffic volume,and road grade remain unclear owing to a lack of compre-hensive,multi-category,and real *** real maintenance data from 340 arterial highway segments in China,this study conducts the life cycle assessment(LCA)to estimate CO_(2) emissions from maintenance activities and examines the primary emission sources among various structural layers and ***,multiple linear regression(MLR)analysis is conducted to investigate the impact of traffic volume,road grade,and pavement deterioration on CO_(2) emissions from maintenance projects,and factors influencing the early-stage degradation of pavement *** results demonstrate that average CO_(2) emissions from heavy rehabilitation projects are 6.97 times higher than those from medium rehabilitation *** from heavy rehabilitation projects exhibit a significantly negative linear relationship with the riding quality index(RQI)before maintenance(plitation projects show a significant negative linear relationship with the pavement condition index(PCI)before maintenance(plitation projects are significantly positively correlated with heavy vehicle traffic volume before maintenance(plitation and RQI after medium rehabilitation exhibit significantly negative linear relationships with their respective in-dicators before maintenance(p<0.05).The early-stage d

关键词： life cycle assessment(LCA) Arterial highway Maintenance Emission factor Pavement performance Traffic volume

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Effects of Surgical Ventricular Restoration on Left Ventricular Shape, Size, and Function for Left Ventricular Anterior Aneurysm

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Chinese Medical Journal 2017年第12期130卷 1429-1434页

作者： yao wang chang-qing gao gang wang Yan-Song Shen Department of Cardiovascular Surgery Chinese People's Liberation Army General Hospital Beijing 100853 China

Background： Surgical ventricular restoration （SVR） has been performed to treat left ventricular （LV） aneurysm. However, there is limited analysis of changes in LV shape. This study aimed to evaluate the changes in LV shape induced by SVR and the effects of SVR on LV size and function for LV aneurysm. Methods： Between April 2006 and March 2015, 18 patients with dyskinetic （dyskinetic group） and 12 patients with akinetic （akinetic group） postinfarction LV anterior aneurysm receiving SVR with the Dor procedure at Chinese People＇s liberation Army General Hospital were enrolled in this study. A retrospective analysis was carried out using data from the echocardiography database. LV shape was analyzed by calculating the apical conicity index （ACI）. LV end-diastolic volume index, end-systolic volume index, and ejection fraction （EF） were measured. One-way analysis of variance was used to compare means at different time points within each group. Results： Within one week after SVR, LV shape became more conical in the two groups （ACI decreased from 0.84 ± 0.13 to 0.69 ± 0.11 [t = 5.155, P = 0.000] in dyskinetic group and from 0.73 ± 0.07 to 0.60 ± 0.11 [t = 2.701, P = 0.026] in akinetic group; LV volumes were decreased significantly and became closer to normal values and EF was improved significantly in the two groups）. On follow-up at least one year, LV shape remained unchanged in dyskinetic group （ACI increased from 0.69 ± 0.11 to 0.74 ± 0.12, t = - 1.109, P = 0.294）, but became more spherical in akinetic group （ACI significantly increased from 0.60 ± 0.11 to 0.75 ±0.11, t = -I .880, P = 0.047）; LV volumes remained unchanged in dyskinetic group, but increased significantly in akinetic group and EF remained unchanged in the two groups. Conclusions： SVR could reshape LV to a more conical shape and a more normal size and improve LV function significantly early after the procedure in patients with dyskinetic or akinetic postinfarction LV anterior aneurysm. However, LV tends to

关键词： Cardiac Aneurysm Echocardiography Left Ventricle Remodeling Left Ventricular Function Surgery

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Echocardiographic Follow-up of Robotic Mitral Valve Repair for Mitral Regurgitation due to Degenerative Disease

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Chinese Medical Journal 2016年第18期129卷 2199-2203页

作者： yao wang chang-qing gao Yan-Song Shen gang wang Department of Cardiovascular Surgery Chinese People's Liberation Army General Hospital Beijing 100853 China

Background： Mitral valve （MV） repair can now be carried out through small incisions with the use of robotic assistance. Previous reports have demonstrated the excellent clinical result of robotic MV repair for degenerative mitral regurgitation （MR）. However, there has been limited infomlation regarding tile echocardiographic follow-up of these patients. The present study was therefore to evaluate the echocardiographic follow-up outcomes after robotic MV repair in patients with MR due to degenerative disease of the MV. Methods： A retrospective analysis was undertaken using data from the echocardiographic database of our department. Between March 2007 and February 2015, 84 patients with degenerative MR underwent robotic MV repair. The repair techniques included leaflet resection in 67 patients （79.8%）, artificial chordae in 20 （23.8%）, and ring annuloplasty in 79 （94.1%）. Eighty-one （96.4%） of the 84 patients were eligible for echocardiographic follow-up assessment, and no patients were lost to follow-up. Results： At a median echocardiographic follow-up of 36.0 months （interquartile range 14.3-59.4 months）, lbur patients （4.9%） developed recurrent mild MR, and no patients had more than mild MR. Mean MR grade, leli atrial diameter （LAD）, left ventricular end-diastolic diameter （LVEDD）, and let1 ventricular ejection fraction （LVEF） were significantly decreased when compared with preoperative values. Mean MR grade decreased from 3.96 ± 0.13 to 0.17 ± 0.49 （Z- -8.456, P 〈 0.001 ）, LAD from 43.8 ± 5.9 to 35.5 ± 3.8 mm （I - 15.131, P 〈 0.001 ）, LVEDD fiom 51.0 ± 5.0 to 43.3 ± 2.2 mm （t = 14.481, P 〈 0.001 ）, and LV EF l＇rom 67.3 ± 7.0% to 63.9 ± 5.1% （t = 4.585, P 〈 0.001 ）. Conclusion： Robotic MV repair for MR due to degenerative disease is associated with a low rate of recurrent MR, and a significant improvement in MR grade, LAD, and LVEDD, but a significant decrease in LVEF at echocardiographic follow-up.

关键词： Degenerative Disease Mitral Regurgitation Mitral Valve Repair

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Deep chemical identification of phytoecdysteroids in Achyranthes bidentata Blume by UHPLC coupled with linear ion trap-Orbitrap mass spectrometry and targeted isolation

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Chinese Journal of Natural Medicines 2022年第7期20卷 551-560页

作者： wang Ying-Ying li jia-Yuan yao chang-liang ZHANG jian-qing YU Yang yao Shuai gao Min WU Shi-Fei WEI Wen-Long BI Qi-Rui GUO De-An School of Chinese Materia Medica Nanjing University of Chinese MedicineNanjing 210023China Shanghai Research Center for Modernization of Traditional Chinese Medicine Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China School of Pharmaceutical Sciences University of Chinese Academy of SciencesBeijing 100049China

Achyranthes bidentata Blume is widely used as a traditional Chinese medicine with the effects of nourishing the liver and kidneys and strengthening muscles and *** this work,a rapid and simple strategy was developed for characterizing phytoecdysteroids by ultra-high-performance liquid chromatography coupled with liner ion trap-Orbitrap mass spectrometry using electrospray ionization in the negative *** a result,47 phytoecdysteroids were unambiguously or tentatively *** them,seven known compounds were identified according to the reference standards along with molecular formula,retention time and fragmentation patterns,while others were mostly potential new *** targeted isolation,the structures of three new compounds were determined by NMR spectra,which were consistent with LC-MS *** present study provides an efficient method to deeply characterize phytoecdysteroids.

关键词： Achyranthes bidentata Blume Chemical identification Fragmentation behaviors Phytoecdysteroids Targeted isola-tion

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Particle-in-cell mode beam dynamics simulation of the low energy beam transport for the SSC-linac injector

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Chinese Physics C 2011年第5期35卷 500-504页

作者： XIAO Chen HE Yuan YUAN You-Jin yao qing-gao wang Zhi-Jun chang Wei liU Yong XIA jia-Wen Institute of Modern Physics Chinese Academy of Sciences Lanzhou 730000 China Graduate University of Chinese Academy of Sciences Beijing 100049 China The School of Nuclear Science and Technology Lanzhou University Lanzhou 730000 China

A new SSC-linac system （injector into separated sector cyclotron） is being designed in the HIRFL （heavy ion research facility of Lanzhou）. As part of SSC-linac, the LEBT （low energy beam transport） consists of seven solenoids, four quadrupoles, a bending magnet and an extra multi-harmonic buncher. The total length of this segment is about 7 meters. The beam dynamics in this LEBT has been studied using three-dimensional PIC （particle-in-cell） code BEAMPATH. The simulation results show that the continuous beam from the ion source is first well analyzed by a charge-to-mass selection system, and the beam of the selected charge-to-mass ratio is then efficiently pre-bunched by a multi-harmonic buncher and optimally matched into the RFQ （radio frequency quadrupole） for further acceleration. The principles and effects of the solenoid collimation channel are discussed, and it could limit the beam emittance by changing the aperture size.

关键词： SSC-linac LEBT PIC mode optimal injection collimation

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Blinding assessment in clinical trials of traditional Chinese medicine:Exploratory principles and protocol

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Journal of Integrative Medicine 2023年第6期21卷 528-536页

作者： Xiao-cong wang Xiao-yu liu Kang-le Shi qing-gang Meng Yue-fan Yu Shi-yao wang Juan wang chang Qu Cong Lei Xin-ping Yu School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing 100029China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China School of Basic Medicine Heilongjiang University of Chinese MedicineHarbin 150040Heilongjiang ProvinceChina

As one of the key components of clinical trials, blinding, if successfully implemented, can help to mitigate the risks of implementation bias and measurement bias, consequently improving the validity and reliability of the trial results. However, successful blinding in clinical trials of traditional Chinese medicine(TCM) is hard to achieve, and the evaluation of blinding success through blinding assessment lacks established guidelines. Taking into account the challenges associated with blinding in the TCM field, here we present a framework for assessing blinding. Further, this study proposes a blinding assessment protocol for TCM clinical trials, building upon the framework and the existing methods. An assessment report checklist and an approach for evaluating the assessment results are presented based on the proposed protocol. It is anticipated that these improvements to blinding assessment will generate greater awareness among researchers, facilitate the standardization of blinding, and augment the blinding effectiveness. The use of this blinding assessment may further advance the quality and precision of TCM clinical trials and improve the accuracy of the trial results. The blinding assessment protocol will undergo continued optimization and refinement, drawing upon expert consensus and experience derived from clinical trials.

关键词： Traditional Chinese medicine Blinding assessment Evaluation protocol Assessment report

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Robust Sliding-mode Filtering for a Class of Uncertain Nonlinear Discrete-time State-delayed Systems

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自动化学报 2006年第1期32卷 96-100页

作者： WU li-gang wang chang-Hong ZENG qing-Shuang gao Hui-Jun Space Control and Inertial Technology Research Center Harbin Institute of Technology Harbin 150001

This paper is concerned with the problem of robust sliding-mode filtering for a class of uncertain nonlinear discrete-time systems with time-delays. The nonlinearities are assumed to satisfy global lipschitz conditions and parameter uncertainties are supposed to reside in a polytope. The resulting filter is of the Luenberger type with the discontinuous form. A sufficient condition with delay-dependency is proposed for existence of such a filter. And the desired filter can be found by solving a set of matrix inequalities. The resulting filter adapts for the systems whose noise input is real functional bounded and not be required to be energy bounded. A numerical example is given to illustrate the effectiveness of the proposed design method.

关键词：鲁棒控制滑动模式滤波器离散系统状态延迟线性矩阵不等式

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