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基于模糊控制算法的多点压边力控制系统的设计与实现

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科学技术与工程 2006年第17期6卷 2697-2701页

作者：刘礴王仲奇张旭东王武坤西北工业大学机电学院西安710072

介绍了目前压边力控制技术的最新发展,其次描述了一套八点可变压边力分区控制系统,可以实现随着拉深行程的变化实时改变压边力。重点介绍了控制系统的硬件结构与工作原理,控制系统软件的设计思路与实现方法。

关键词：变压边力多点控制VB 多线程模糊控制控制系统

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手提式电磁铆枪减振研究

新技术新工艺 2006年第7期 26-28页

作者：王武坤曹增强樊战亭刘礴西北工业大学机电学院陕西西安710072 咸阳师范学院陕西咸阳712000

在试验的基础上得出手提式电磁铆枪回弹体质量对输出力和后坐力的关系。通过MAT-LAB对其隔振系统的传递系数进行分析,优化其各个参数。通过试验表明,优化后铆枪的后坐力明显减小。

关键词：电磁铆枪输出力后坐力隔振系统

A Combined Experimental and Numerical Study of Shotcrete Jets and Related Wet Spray Nozzles

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Fluid Dynamics & Materials Processing 2020年第5期16卷 947-960页

作者： Chang Su Qiangqiang Zheng wukun Zhao State Key Laboratory of Mining Response and Disaster Prevention and Control in Deep Coal Mines Huainan232001China School of Mechanical Engineering Anhui University of Science and TechnologyHuainan232001China School of Civil Engineering and Architecture Anhui University of Science and TechnologyHuainan232001China State Key Laboratory of Safety and Health for Metal Mines Maanshan243000China

In this research,the dynamics of wet spray nozzles with different geometries,used to accelerate shotcrete,are investigated on the basis of a suitable three-dimensional mathematical model and related numerical *** have been conducted in the frame of the SIMPLEC *** k-εturbulence model has been used to account for turbulent *** study shows that when the angle of the convergent section is less than 3°,it has a scarce effect on the dynamics of the jet of shotcrete;with the increase of the convergence angle,the shotcrete jet velocity decreases and the nozzle wear increases;when this angle is greater than 6°,the concrete outlet jet velocity is very small and the nozzle can easily be *** results are in good agreement with the outcomes of the numerical simulations,which indicates that the used approach is reliable.

关键词： Shotcrete wet spraying nozzle turbulence flow convergence angle numerical simulation

Numerical Simulation of Temperature and Stress Fields of Ti-Alloy Thin-well Barrel during Quenching Process

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材料热处理学报 2004年第05B期25卷 769-771页

作者： LIYan-zeng YANMu-fu wukun SchoolofMaterialsScienceandEngineering HarbinInstituteofTechnologyHarbinChina

The mathematical models have been established to describe the temperature and stress profiles in T16A14V cylinder during quenching. The residual stress and deformation of the workpiece can be predicted precisely based on ANSYS software. The simulated results show that the temperature of the divided element decreases faster at the edge than that at the internal of the workpiece during quenching from 1050 to 20°C. The largest temperature difference and dimension change in diameter are about 90°C and -0.935%, respectively. The position of largest tensile stress occurs around the edge of the cylinder.

关键词： FEM 温度场应力场数值模拟淬火钛合金

A multiplexed time-resolved fluorescence resonance energy transfer ultrahigh-throughput screening assay for targeting the SMAD4–SMAD3–DNA complex

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Journal of Molecular Cell Biology 2023年第11期15卷 21-32页

作者： wukun Ouyang Qianjin Li Qiankun Niu Min Qui Haian Fu Yuhong Du Xiulei Mo Department of Pharmacology and Chemical Biology Emory University School of MedicineAtlantaGA 30322USA Emory Chemical Biology Discovery Center Emory University School of MedicineAtlantaGA 30322USA Department of Hematology and Medical Oncology and Winship Cancer Institute Emory UniversityAtlantaGA 30322USA

The transforming growth factor-beta(TGFβ)signaling pathway plays crucial roles in the establishment of an immunosuppressive tumor microenvironment,making anti-TGFβagents a significant area of interest in cancer ***,the clinical translation of current anti-TGFβagents that target upstream cytokines and receptors remains ***,the development of small-molecule inhibitors specifically targeting SMAD4,the downstream master regulator of the TGFβpathway,would offer an alternative approach with significant therapeutic potential for anti-TGFβ*** this study,we present the development of a cell lysate-based multiplexed time-resolved fluorescence resonance energy transfer(TR-FRET)assay in an ultrahigh-throughput screening(uHTS)1536-well plate *** assay enables simultaneous monitoring of the protein–protein interaction between SMAD4 and SMAD3,as well as the protein–DNA interaction between SMADs and their consensus DNA-binding *** multiplexed TR-FRET assay exhibits high sensitivity,allowing the dynamic analysis of the SMAD4–SMAD3–DNA complex at single-amino acid ***,the multiplexed uHTS assay demonstrates robustness for screening small-molecule *** a pilot screening of an FDA-approved bioactive compound library,we identified gambogic acid and gambogenic acid as potential hit *** proof-of-concept findings underscore the utility of our optimized multiplexed TR-FRET platform for large-scale screening to discover small-molecule inhibitors that target the SMAD4–SMAD3–DNA complex as novel antiTGFβsignaling agents.

关键词： TGFβ/SMAD4 signaling high-throughput screening TR-FRET

Building Better Full Manganese‑Based Cathode Materialsfor Next‑Generation Lithium‑Ion Batteries

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Electrochemical Energy Reviews 2023年第1期6卷 148-185页

作者： Jin Song Hangchao wang Yuxuan Zuo Kun Zhang Tonghuan Yang Yali Yang Chuan Gao Tao Chen Guang Feng Zewen Jiang wukun Xiao Tie Luo Dingguo Xia Beijing Key Laboratory of Theory and Technology for Advanced Battery Materials School of Materials Science and EngineeringPeking UniversityBeijing 100871China College of Chemistry and Molecular Science Wuhan UniversityWuhan 430072HubeiChina College of Engineering Peking UniversityBeijing 100871China

Lithium-manganese-oxides have been exploited as promising cathode materials for many years due to their environmental friendliness,resource abundance and low ***,inevitable problems,such as Jahn-Teller distortion,manganese dissolution and phase transition,still frustrate researchers;thus,progress in full manganese-based cathode materials(FMCMs)has been relatively slow and limited in recent ***,with the fast growth of vehicle electrification and large-scale energy-storage grids,there has been an urgent demand to develop novel FMCMs again;actually,new waves of research based on FMCMs are being ***,we systematically review the history of FMCMs,correctly describe their structures,evaluate the advantages and challenges,and discuss the resolution strategies and latest ***,beyond FMCMs,a profound discussion of current controversial issues,such as oxygen redox reaction,voltage decay and voltage hysteresis in Li_(2)MnO_(3)-based cathode materials,is also *** review summarizes the effectively optimized approaches and offers a few new possible enhancement methods from the perspective of the electronic-coordination-crystal structure for building better FMCMs for next-generation lithium-ion batteries.

关键词： Energy storage Lithium-ion batteries Cathode materials Manganese oxides

Micro-interfaces modulation by UV-ozone substrate treatment for MPEA vapor fluorescence detection

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Nano Research 2023年第3期16卷 4055-4060页

作者： Bin Li Keke Li Wei Xu Mingzhu Yan Jianhao Zhao wukun Zhang Mingshuai Yuan Yanyan Fu Qingguo He Jiangong Cheng State Key Lab of Transducer Technology Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghai 200050China School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

Drug abuse directly endangers human health and social security,hence its sensitive and rapid detection is vitally *** recent years,organic film-based fluorescent sensing technology has attracted more and more attention in the detection of drugs and explosives due to its advantages of simple operation and rapid *** film-based fluorescent sensors,in addition to sensitive materials,the surface morphology of the film is also an important factor affecting the *** previous studies,the regulation of surface morphology mainly depends on concentration changes or complex ***,a novel fluorescent polymer probe was designed and synthesized,and a simple and efficient ultraviolet(UV)-ozone substrate treatment method is used to adjust their surface *** results show that film has an excellent fluorescence enhancement effect upon exposure to methylphenethylamine(MPEA,a simulant of methamphetamine)*** sensing effect of the film is significantly improved after UV-ozone substrate treatment,and the limit of detection was decreased by 10.4 times from 2.59 to 0.25 *** experiments show that the sensing performance of other fluorescent probe can also be improved by the UV-ozone substrate *** convenient and general method may become a very effective approach to improve the performance of film-based fluorescent sensors.

关键词： fluorescence sensing ultraviolet(UV)-ozone substrate treatment organic sensing materials film-based gas sensors

Numerical Prediction of Compound Layer Growth of Steel En40B during Plasma Nitriding

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材料热处理学报 2004年第05B期25卷 776-778页

作者： DAIYa-nan YANMu-fu LEITing-quan wukun SchoolofMaterialsScienceandEngineering HarbinInstituteofTechnologyHarbinChina

This paper deals with the kinetics of compound layer growth of steel En40B plasmas nitrided at 520°C for different time and establishes the corresponding mathematical model based on the thermodynamics and kinetics of nitrogen diffusion process. The results show that the compound layer consists of dual phases e (Fe2-3N) and / (Fe4N) and its thickness increases with increasing nitriding time. The calculated data indicate that the critical concentration between compound layer and diffusion one is about 0.82wt%. The computer simulation results demonstrate that predicted compound layer thickness agrees with the measured data.

关键词：等离子渗氮 En40B钢化合层计算机模拟

Analysis of Valence Electron Structure in Compound Layer of Steel 42CrMo Plasma Nitrided with Rare Earth Addition

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材料热处理学报 2004年第5期25卷 322-324页

作者： LIUZhan-hong YANMu-fu DAIYa-nan wukun SchoolofMaterialsScienceandEngineering HarbinInstituteofTechnologyHarbinChina

The valence electron structure (VES) in compound layer of steel plasma-nitrided at 560°C with rare earth (RE) addition was calculated based on the empirical electron theory (EET) of solids and molecules and BLD method. The results show that the presence of RE atoms diffused into surface layer leads to an increase of phase structure factor, which explains the catalyzing and micro-alloying effects of RE.

关键词： 42CrMo钢等离子渗氮稀土价电子结构