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Prevalence of hypertension and its associations with body composition across Chinese and American children and adolescents

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World Journal of Pediatrics 2024年第4期20卷 392-403页

作者： Li-wang Gao Yi-wen Huang Hong Cheng Xi wang Hong-bo Dong Pei Xiao Yin-Kun Yan Xin-Ying Shan Xiao-Yuan Zhao Jie Mi Center for Non-Communicable Disease Management Beijing Children’s HospitalCapital Medical UniversityNational Center for Children’s HealthNo.56 Nanlishi RoadXicheng DistrictBeijing100045China Department of Epidemiology Capital Institute of PediatricsNo.2 Yabao RoadChaoyang DistrictBeijing100020China Key Laboratory of Major Diseases in Children Ministry of EducationBeijingChina

Background The age of onset of hypertension(HTN)is decreasing,and obesity is a significant risk *** prevalence and racial disparities in pediatric HTN and the association between body composition and blood pressure are insufficiently *** study aimed to evaluate the prevalence of HTN in Chinese and American children and adolescents and to assess the relationship between various body composition indices and *** Seven thousand,five hundred and seventy-three Chinese and 6239 American children and adolescents aged 8–18 years from the 2013–2015 China Child and Adolescent Cardiovascular Health study and the 2011–2018 National Health and Nutrition Examination Surveys were *** pressure and body composition(fat and muscle)were measured by trained *** crude prevalence and age-standardized prevalence rate(ASPR)of primary HTN and its subtypes[isolated systolic hypertension(ISH)and isolated diastolic hypertension(IDH)]were calculated based on 2017 American Academy of Pediatrics ***-adjusted linear regression coefficients and odds ratios(ORs)were calculated to assess the associations of body composition indicators with HTN,ISH and *** The ASPR of HTN was 18.5%in China(CN)and 4.6%in the United States(US),whereas the obesity prevalence was 7.4%and 18.6%,and the population attributable risk of HTN caused by overweight and obesity was higher in the US than in *** fat mass,muscle mass and body fat percentage mass were associated with a higher risk of HTN in both *** percent of muscle body mass had a protective effect on HTN and ISH in both countries[HTN(CN:OR=0.83,95%CI=0.78–0.88;US:OR=0.72,95%CI=0.64–0.81);ISH(CN:OR=0.87,95%CI=0.80–0.94;US:OR=0.71,95%CI=0.62–0.81)],and the protective effect was more common among children and adolescents with high levels of physical *** The burden of HTN in Chinese children and adolescents was substantial and much greater than that in the US,and th

关键词： body composition Children and adolescents China Child and Adolescent Cardiovascular Health Hypertension National Health and Nutrition Examination Surveys

Properties, hazards and valuable metal recovery technologies of red mud: A review

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PARTICUOLOGY 2024年第10期93卷 328-348页

作者： Du, Peixin wang, Peng Zhang, Xueqian wen, Guangwu wang, Yishan Shandong Univ Technol Sch Mat Sci & Engn Zibo 255000 Peoples R China

This review presents a summary of the research conducted thus far on the recovery of various types of valuable metals from red mud. The composition, properties, environmental hazards, and current status of comprehensive utilization of red mud were studied. A number of studies have been conducted on the use of red mud as a modifying additive for cement, the development of various catalysts based on red mud, and the recovery of various valuable metals from red mud. Furthermore, we examine several techniques for extracting various types of valuable metals from red mud, including pyrometallurgical recovery, wet leaching recovery, and emerging biobased technology recovery. We investigate the underlying principles, processes, research progress, and the potential for industrial application of these methods, and assess the advantages and disadvantages of each from the perspectives of economic and environmental benefits. Although these methods have certain disadvantages, in general, the recovery of various types of valuable metals from red mud is an effective way to solve the problem of red mud and the supply of metal raw materials. In conclusion, this paper presents an overview of the current state of red mud development and utilization, as well as the various methods employed for the recovery of valuable metals from red mud. (c) 2024 Chinese Society of Particuology and Institute of Process Engineering, Chinese Academy of Sciences. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.

关键词： Red mud Utilization Environment hazard Valuable metal Recovery LEACHING BEHAVIOR IRON RECOVERY ACID SEPARATION EXTRACTION REDUCTION MICROWAVE SCANDIUM ELEMENTS ORE

Fanlian Huazhuo Formula alleviates high-fat diet-induced nonalcoholic fatty liver disease by modulating autophagy and lipid synthesis signaling pathway

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World Journal of Gastroenterology 2024年第30期30卷 3584-3608页

作者： Meng-Yuan Niu Geng-Ting Dong Yi Li Qing Luo Liu Cao Xi-Min wang Qi-wen wang Yi-Ting wang Zhe Zhang Xi-wen Zhong Wei-bo Dai Le-Yu Li Pharmacology Laboratory Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese MedicineZhongshan 528400Guangdong ProvinceChina Department of Endocrinology Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese MedicineZhongshan 528400Guangdong ProvinceChina

BACKGROUND Fanlian Huazhuo Formula(FLHZF)has the functions of invigorating spleen and resolving phlegm,clearing heat and purging *** has been identified to have therapeutic effects on type 2 diabetes mellitus(T2DM)in clinical ***-alcoholic fatty liver disease(NAFLD)is frequently diagnosed in patients with ***,the therapeutic potential of FLHZF on NAFLD and the underlying mechanisms need further *** To elucidate the effects of FLHZF on NAFLD and explore the underlying hepatoprotective mechanisms in vivo and in *** HepG2 cells were treated with free fatty acid for 24 hours to induce lipid accumulation cell ***,experiments were conducted with the different concentrations of freeze-dried powder of FLHZF for 24 hours.C57BL/6 mice were fed a high-fat diet for 8-week to establish a mouse model of NAFLD,and then treated with the different concentrations of FLHZF for 10 *** FLHZF had therapeutic potential against lipid accumulation and abnormal changes in biochemical indicators in vivo and in *** experiments verified that FLHZF alleviated abnormal lipid metabolism might by reducing oxidative stress,regulating the AMPKα/SREBP-1C signaling pathway,activating autophagy,and inhibiting hepatocyte *** FLHZF alleviates abnormal lipid metabolism in NAFLD models by regulating reactive oxygen species,autophagy,apoptosis,and lipid synthesis signaling pathways,indicating its potential for clinical application in NAFLD.

关键词： Fanlian Huazhuo Formula Nonalcoholic fatty liver disease Autophagy Apoptosis AMPKα/SREBP-1C signal pathway Oxidative stress

Applications of single-cell RNA sequencing in spermatogenesis and molecular evolution

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Zoological Research 2024年第3期45卷 575-585页

作者： wen-bo Chen Meng-Fei Zhang Fan Yang Jin-Lian Hua College of Veterinary Medicine Shaanxi Centre of Stem Cells Engineering&TechnologyNorthwest A&F UniversityYanglingShaanxi 712100China Key Laboratory of Livestock Biology Northwest A&F UniversityYanglingShaanxi 712100China

Spermatogenic cell heterogeneity is determined by the complex process of spermatogenesis ***,effectively revealing the regulatory mechanisms underlying mammalian spermatogenic cell development and differentiation via traditional methods is *** in technology have led to the emergence of many single-cell transcriptome sequencing protocols,which have partially addressed these *** this review,we detail the principles of 10x Genomics technology and summarize the methods for downstream analysis of single-cell transcriptome sequencing ***,we explore the role of single-cell transcriptome sequencing in revealing the heterogeneity of testicular ecological niche cells,delineating the establishment and disruption of testicular immune homeostasis during human spermatogenesis,investigating abnormal spermatogenesis in humans,and,ultimately,elucidating the molecular evolution of mammalian spermatogenesis.

关键词： Single-cell RNA sequencing(scRNA-seq) Spermatogenesis Molecular evolution Sertoli cell

Synthesis of betanin by expression of the core betalain biosynthetic pathway in carrot

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Horticultural Plant Journal 2024年第3期10卷 732-742页

作者： bo wang Yahui wang Yuanjie Deng Quanhong Yao Aisheng Xiong State Key Laboratory of Crop Genetics and Germplasm Enhancement College of HorticultureNanjing Agricultural UniversityNanjingJiangsu 210095China Shanghai Key Laboratory of Agricultural Genetics and Breeding Biotechnology Research Institute of Shanghai Academy of Agricultural ScienceShanghai 201106China

Betalain has received increased attention because of its high nutritional value and crucial physiological *** on the elucidation of its core biosynthetic pathway,betalain can be produced in additional plants by metabolic *** of betalain in carrot(Daucus carota L.)can improve its nutritional quality and economic value by extracting betalain from the fleshy root,non-edible part,and processing residue of *** this study,two different constructs,namely,pYB:mCD(AomelOS,BvCYP76AD1S,and BvDODA1S)and p YB:CDD(BvCYP76AD1S,BvDODA1S,and MjcDOPA5GTS),were introduced into carrot for betanin synthesis by Agrobacterium-mediated *** can be synthetized in both transgenic calli,and p YB:m CD-transgenic callus can be used to produce betacyanin by suspension ***,pYB:mCD-transgenic seedlings can synthetize betanin only by tyrosine *** p YB:CDD-transgenic lines can synthetize betanin in whole *** betanin content in fleshy root of pYB:CDD-transgenic carrot was(63.4±9)μg·g^(-1)fresh weight according to quantitative *** betanin-producing carrot plant materials can be used to synthesize betanin for industrial application or consumption as dietary sources.

关键词： Daucus carota L. Betanin Biosynthesis Metabolic engineering Biofortification

Progress and future prospects of decadal prediction and data assimilation:A review

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Atmospheric and Oceanic Science Letters 2024年第1期17卷 53-62页

作者： wen Zhou Jinxiao Li Zixiang Yan Zili Shen bo Wu Bin wang Ronghua Zhang Zhijin Li Key Laboratory of Polar Atmosphere-ocean-ice System for Weather and Climate of the MOE Department of Atmospheric and Oceanic Science&Institute of Atmospheric ScienceFudan UniversityShanghaiChina Key Laboratory for Polar Science of the MNR Polar Research Institute of ChinaShanghaiChina Shanghai Investigation Design and Research Institute Co.Ltd.ShanghaiChina LASG Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina School of Marine Science Nanjing University of Information Science&TechnologyNanjingChina

年代际预测,也称为“近期气候预测”,旨在预测未来1-10年内的气候变化,是气候预测和气候变化研究领域的一个新关注点.它位于季节至年际预测和长期气候变化预测之间,结合了初值问题和外部强迫问题的两个方面.年代际预测的核心技术在于用... 详细信息

年代际预测,也称为“近期气候预测”,旨在预测未来1-10年内的气候变化,是气候预测和气候变化研究领域的一个新关注点.它位于季节至年际预测和长期气候变化预测之间,结合了初值问题和外部强迫问题的两个方面.年代际预测的核心技术在于用于模式初始化的同化方法的准确性和效率,其目标是为模式提供准确的初始条件,其中包含观测到的气候系统内部变率,年代际预测的初始化通常涉及在耦合框架内同化海洋观测,其中观测到的信号通过耦合过程传递到其他分量,如大气和海冰.然而,最近的研究越来越关注在海洋-大气耦合模式中探索耦合数据同化(CDA),有人认为CDA有潜力显著提高年代际预测技巧.本文综合评述了该领域的三个方面的研究现状:初始化方法,年代际气候预测的可预测性和预测技巧,以及年代际预测的未来发展和挑战.

关键词：年代际预测四维数据同化海气相互作用

Single-atom Ag-loaded carbon nitride photocatalysts for efficient degradation of acetaminophen:The role of Ag-atom and O_(2)

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Journal of Environmental Sciences 2024年第5期139卷 12-22页

作者： Yi Yuan wen-Long wang Zhi-Wei wang Jin wang Qian-Yuan Wu Key Laboratory of Microorganism Application and Risk Control of Shenzhen Guangdong Provincial Engineering Research Center for Urban Water Recycling and Environmental SafetyInstitute of Environment and EcologyShenzhen International Graduate SchoolTsinghua UniversityShenzhen 518055China Shenzhen Environmental Science and New Energy Technology Engineering Laboratory Tsinghua-Berkeley Shenzhen InstituteShenzhen 518055China College of Materials Science and Engineering Shenzhen UniversityShenzhen 518071China

Carbon nitride has been extensively used as a visible-light photocatalyst,but it has the disadvantages of a low specific surface area,rapid electron-hole recombination,and relatively low light *** this study,single-atom Ag was successfully anchored on ultrathin carbon nitride(UTCN)via thermal polymerization,the catalyst obtained is called *** Ag hardly changed the carbon nitride's layered and porous physical *** exhibited efficient visible-light photocatalytic performances in the degradation of various recalcitrant pollutants,eliminations of 85% were achieved by visible-light irradiation for *** with Ag improved the photocatalytic performance of UTCN by narrowing the forbidden band gap from 2.49 to 2.36 e V and suppressing electron-hole pair *** addition,Ag doping facilitated O_(2) adsorption on UTCN by decreasing the adsorption energy from -0.2 to -2.22 e V and favored the formation of O_(2)^(·-).Electron spin resonance and radical-quenching experiments showed that O_(2)^(·-)was the major reactive species in the degradation of Acetaminophen(paracetamol,APAP).

关键词： Ag single atom Carbon nitride Photocatalysis Visible light Adsorption energy Reactive species

Postoperative pneumocranium after endoscopic transnasal optic canal decompression

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 973-975页

作者： Sheng-Jian Lu bo Yu wen-Can Wu The Eye Hospital School of Ophthalmology&OptometryWenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina

Dear Editor,We present the first time,a case of a patient developed cerebrospinal fluid(CSF)leak and pneumocranium following optic canal decompression(OCD).INTRODUCTION Indirect traumatic optic neuropathy(ITON)impairs visual functions and quality of *** transnasal optic canal decompression(ETOCD)is one of the standard treatment strategies for the *** the ETOCD,the optic nerve sheath are usually incised for sufficient decompression of optic nerve after removal of optic canal,which is associated with complications like CSF leakage,ophthalmic artery injury,and optic nerve injury[1].Generally,the mild CSF leak is common and can heal spontaneously using conventional treatment,the severe CSF leak requires surgical repair[2].

关键词： decompression nasal traumatic

交联度对瓜尔胶-g-聚丙烯酸/腐植酸钠高吸水性树脂性能的影响

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高分子材料科学与工程 2009年第12期25卷 41-44页

作者：王文波王爱勤中国科学院兰州化学物理研究所环境材料与生态化学发展中心甘肃兰州730000 中国科学院研究生院北京100049

以天然瓜尔胶(GG),丙烯酸(AA)和腐植酸钠(SH)为原料,N,N′-亚甲基双丙烯酰胺(MBA)为交联剂,过硫酸铵(APS)为引发剂,采用水溶液聚合法制备了不同交联度的瓜尔胶接枝聚丙烯酸/腐植酸钠(GG-g-PAA/SH)高吸水性树脂。研究了交联度对树脂的表... 详细信息

以天然瓜尔胶(GG),丙烯酸(AA)和腐植酸钠(SH)为原料,N,N′-亚甲基双丙烯酰胺(MBA)为交联剂,过硫酸铵(APS)为引发剂,采用水溶液聚合法制备了不同交联度的瓜尔胶接枝聚丙烯酸/腐植酸钠(GG-g-PAA/SH)高吸水性树脂。研究了交联度对树脂的表面形态、溶胀动力学、盐敏感度和反复溶胀性能的影响。扫描电镜(SEM)和溶胀性能测试结果表明,交联度的增加可以改善高吸水性树脂的均匀度,提高吸水速率,降低对盐的敏感度,以及改进树脂的反复溶胀性能。

关键词：高吸水性树脂瓜尔胶腐植酸交联度溶胀