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Expert Consensus on Pathological Diagnosis of Intrahepatic Cholangiocarcinoma(2022 version)

Journal of Clinical and Translational Hepatology 2023年第7期11卷 1553-1564页

作者： Han wang Jun Chen Xin zhang Xia Sheng xiao-yan Chang Jie Chen Min-Shan Chen Hui Dong Guang-Jie Duan He-Ping Hu Zhi-Yong Huang wei-Dong Jia xiao-qing Jiang Dong Kuang Shan-Shan Li Zeng-Shan Li Chang-Li Lu Shu-Kui Qin Xue-Shan Qiu Li-Juan Qu Chun-Kui Shao Feng Shen Guo-ming Shi Su-Sheng Shi Yu-Jun Shi Hui-Chuan Sun xiao-Dong Teng Bin wang Zhan-Bo wang Tian-Fu Wen Jia-Mei yang Qiao-Qiao yang Sheng-Long Ye Hong-Fang Yin Zhen-Gang Yuan Jing-Ping Yun Feng-Lin Zang Hong-Qi zhang Li-Hong zhang Jing-Min zhao Jian Zhou wei-Xun Zhou Jia Fan xiao-Ping Chen Wan Yee Lau Yuan Ji Wen-ming Cong Chinese Society of Liver Cancer of Chinese Anti-Cancer Association Digestive Disease Group of Chinese Society of Pathology,Chinese Medical Association Chinese Society of Pathology of Chinese Anti-Cancer Association Hepatic Surgery Group of Chinese Society of Surgery,Chinese Medical Association Biliary Tract Tumor Committee of China Anti-Cancer Association Chinese Society of Clinical Oncology IDepartment of Pathology Eastern Hepatobilary Surgery HospitalNaval Medical UniversityShanghaiChina Department of Pathology the Affiliated Drum Tower HospitalNanjing University Medical SchoolNanjingJiangsuChina Department of Pathology Zhongshan HospitalFudan UniversityShanghaiChina Department of Pathology Minhang HospitalFudan Uni-versityShanghaiChina Department of Pathology Peking Union Medical College HospitalChinese Academy of Medical Sci-ences and Peking Union Medical CollegeBeijingChina Department of Liver Surgery Sun Yat-Sen University Cancer CenterGuangzhouGuangdongChina Department of Pathology The First Affiliated HospitalArmy Medical UniversityChongqingChina Department of Hepatobiliary Medicine Eastern Hepatobiliary Surgery HospitalNaval Medical UniversityShanghaiChina Hepatic Surgery Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWu-hanHubeiChina Department of General Surgery The First Affliated Hospital of USTCDivision of Life Science and Medi-cineUniversity of Science and Technology of ChinaHefeiAnhuiChina Department of Biliary Surgery I Eastern Hepatobil-iary Surgery HospitalNaval Medical UniversityShanghaiChina Department of Pathology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubeiChina Department of Pathology The First Afiliated Hospital of Zhengzhou UniversityZhengzhou UniversityZhengzhouHenanChina Department of Pathology Xijing Hospi-talAir Force Medical UniversityXi'anShaanxiChina Department of Pathology West China HospitalSichuan UniversityChengduSichuanChina Cancer Center of Jinling Hospital Nanjing University of Chinese MedicineNanjingJiangsuChina Department of Pathology The First Affiliated HospitalChina Medical UniversityShenyangLiaoningChina Department of Pathology The 900 Hospital of the Chinese People's Liberation Army Joint Logistics TeamFuzhouFujianChina Department of Pathology The Third Affiliated HospitalSun Yat-Sen UniversityGuangz

Intrahepatic cholangiocarcinoma(iCCA)can originate from the large bile duct group(segment bile ducts and area bile ducts),small bile duct group(septal bile ducts and interlobular bile ducts),and terminal bile duct group(bile ductules and canals of Hering)of the intrahepatic biliary tree,which can be histopathological corresponding to large duct type iCCA,small duct type iCCA and iCCA with ductal plate malformation pattern,and cholangiolocarcinoma,*** challenge in pathological diagnosis of above subtypes of iCCA falls in the distinction of cellular morphologies,tissue structures,growth patterns,invasive behaviors,immunophenotypes,molecular mutations,and surgical *** these reasons,this expert consensus provides nine recommendations as a reference for standardizing and refining the diagnosis of pathological subtypes of iCCA,mainly based on the 5th edition of the World Health Organization Classification of Tumours of the Digestive System.

关键词： Intrahepatic cholangiocarcinoma Pathology Histological type Immunohistochemistry Molecular variation

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The DIRECT consortium and the REST-meta-MDD project:towards neuroimaging biomarkers of major depressive disorder

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Psychoradiology 2022年第1期2卷 32-42页

作者： xiao Chen Bin Lu Hui-Xian Li Xue-Ying Li Yu-wei wang Francisco Xavier Castellanos Li-Ping Cao Ning-Xuan Chen wei Chen Yu-Qi Cheng Shi-Xian Cui zhao-Yu Deng Yi-Ru Fang Qi-Yong Gong Wen-Bin Guo Zheng-Jia-Yi Hu Li Kuang Bao-Juan Li Le Li Tao Li Tao Lian Yi-Fan Liao yan-Song Liu Zhe-Ning Liu Jian-Ping Lu qing-Hua Luo Hua-qing Meng Dai-Hui Peng Jiang Qiu Yue-Di Shen Tian-Mei Si yan-qing Tang Chuan-Yue wang Fei wang Hua-Ning wang Kai wang Xiang wang Ying wang Zi-Han wang xiao-Ping Wu Chun-ming Xie Guang-Rong Xie Peng Xie Xiu-Feng Xu Hong yang Jian yang Shu-Qiao Yao Yong-Qiang Yu Yong-Gui Yuan Ke-Rang zhang wei zhang Zhi-Jun zhang Jun-Juan Zhu Xi-Nian Zuo Jing-Ping zhao Yu-Feng Zang the DIRECT consortium Chao-Gan yan CAS Key Laboratory of Behavioral Science Institute of PsychologyChinese Academy of SciencesBeijing 100101China International Big-Data Center for Depression Research Chinese Academy of SciencesBeijing 100101China Magnetic Resonance Imaging Research Center Institute of PsychologyChinese Academy of SciencesBeijing 100101China Department of Psychology University of Chinese Academy of SciencesBeijing 100049China Sino-Danish College University of Chinese Academy of SciencesBeijing 101408China Sino-Danish Center for Education and Research Graduate University of Chinese Academy of SciencesBeijing 101408China Department of Child and Adolescent Psychiatry NYU Grossman School of MedicineNew YorkNY 10016USA Nathan Kline Institute for Psychiatric Research OrangeburgNew YorkNY 10962USA 9Affiliated Brain Hospital of Guangzhou Medical UniversityGuangzhou 510370China Capital Normal University Beijing 100089China Department of Psychiatry Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou 310020ZhejiangChina Department of Psychiatry First Affiliated Hospital of Kunming Medical UniversityKunmingYunnan 650032China Shanghai Mental Health Center Shanghai Jiao Tong University School of MedicineShanghai 200030China Huaxi MR Research Center(HMRRC) Department of RadiologyWest China Hospital of Sichuan UniversityChengduSichuan 610044China Research Unit of Psychoradiology Chinese Academy of Medical SciencesChengduSichuan 610052China Department of Psychiatry and National Clinical Research Center for Mental DisordersThe Second Xiangya Hospital of Central South UniversityChangsha 410011HunanChina Department of Psychiatry The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400042China Xijing Hospital of Air Force Military Medical University Xi’anShaanxi 710032China Center for Cognitive Science of Language Beijing Language and Culture UniversityBeijing 100083China Affiliated Mental Health Center&Hangzhou Seventh People’s Hospital Zhejiang University School of

Despite a growing neuroimaging literature on the pathophysiology of major depressive disorder(MDD),repro-ducible findings are lacking,probably reflecting mostly small sample sizes and heterogeneity in analytic *** address these issues,the Depression Imaging REsearch ConsorTium(DIRECT)was *** REST-meta-MDD project,pooling 2428 functional brain images processed with a standardized pipeline across all participating sites,has been the first effort from *** this review,we present an overview of the moti-vations,rationale,and principal findings of the studies so far from the REST-meta-MDD *** from the first round of analyses of the pooled repository have included alterations in functional connectivity within the default mode network,in whole-brain topological properties,in dynamic features,and in functional *** well-powered exploratory observations have also provided the basis for future longitudinal hypothesis-driven *** these fruitful explorations,DIRECT has proceeded to its second stage of data sharing that seeks to examine ethnicity in brain alterations in MDD by extending the exclusive Chinese original sample to other ethnic groups through international collaborations.A state-of-the-art,surface-based preprocessing pipeline has also been introduced to improve *** images from patients with bipolar disorder and schizophrenia will be included to identify shared and unique abnormalities across diag-nosis *** addition,large-scale longitudinal studies targeting brain network alterations following antidepressant treatment,aggregation of diffusion tensor images,and the development of functional magnetic resonance imaging-guided neuromodulation approaches are *** these endeavours,we hope to accelerate the translation of functional neuroimaging findings to clinical use,such as evaluating longitudinal effects of antidepressant medications and developing individualized

关键词： major depressive disorder DIRECT R-fMRI database neuroimaging

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Chinese expert consensus on the management of hypertension in the very elderly

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Journal of Geriatric Cardiology 2016年第12期13卷 945-953页

作者： Jing LI Yi-Xin HU Wen wang Ning-Yuan FANG Xin-Zheng LU Lin PI Mei-Lin LIU wei-Min LI yan-Fang LI Peng QU Qi HUA qing HE Hai-Ying WU Yuan-ming zhang xiao-Ping CHEN Lu-Yuan CHEN Li FAN Xing-Sheng zhao Zhi-ming ZHU Yi-Nong JIANG Yi-Fang GUO Hong YUAN Ping-Jin GAO Xin-Juan XU Jun CAI Liang-Di XIE Xuan Wu Hospital Capital Medical University Beijing China Chinese PLA General Hospital Beijing China Chinese Academy of Medical Science Fuwai Hospital Beijing China Renji Hospital Medical College of Shanghai Jiao Tong University ShanghaL China Jiang Su Province People's Hospital Jiangsu China Beijing Chui yang Liu Hospital Beijing China Peking University First Hospital Beijing China First Affiliated Hospital of Harbin Medical University Heilongjiang China Beijing An Zhen Hospital Capital Medical University Beijing China The Second Affiliated Hospital of Dalian Medical University Liaoning China Beijing Hospital Beijing China The First Hospital of Xinjiang Medical University Xinjiang Uygur Autonomous Region China West China Hospital Sichuan University Sichuan China The People's Hospital of Guangdong Province Guangdong China Inner Mongolia Autonomous Region People's Hospital Inner Mongolia Autonomous Region China Daping Hospital the Third Military Medical University Chongqing China The First Affiliated Hospital of Dalian Medical University Liaoning China Hebei Province People's Hospital Hebei China Xiangya Third Hospital Central South University Hunan China Shanghai Hypertension Research Institute Shanghai China The First Hospital of Fujian Medical University Fujian China

Population aging has become a major challenge for the healthcare in China. More than 23 million Chinese are cur- rently ≥ 80 years, with an annual increase of 5%. The Chi- nese population of 80 years or older is expe... 详细信息

关键词： Consensus Geriatric Hypertension Octogenarians

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物化探信息综合处理在找矿靶区定量优选中的应用

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矿物岩石地球化学通报 2017年第6期36卷 886-890页

作者：罗建民张琪宋秉田王晓伟杨忠明赵彦庆刘升有甘肃省地质调查院兰州730000 甘肃省地质矿产勘查开发局兰州730000

转变思维方式,将航磁数据改变成与化探数据相同的格式,应用多元统计分析方法建立基于物化探综合信息的区域Au找矿靶区定量预测模型。模型中航磁信息展现出优于Au元素的判别能力。以定量预测模型对全区各研究单元与已知有矿单元做相似程... 详细信息

转变思维方式,将航磁数据改变成与化探数据相同的格式,应用多元统计分析方法建立基于物化探综合信息的区域Au找矿靶区定量预测模型。模型中航磁信息展现出优于Au元素的判别能力。以定量预测模型对全区各研究单元与已知有矿单元做相似程度判定,选择相似程度高的53个单元为一级找矿靶区(每个靶区面积25 km^2),其中18个(34%)靶区内有已知矿床(点)产出,认为,其余35个(66%)预测找矿靶区应该是寻找Au矿的有利区域。此结果不但改变了传统(定性)地质研究中认为,航磁成果对Au矿找矿靶区判定效果不佳的结论,同时更加充分说明,海量数据信息中隐藏着极大的潜能,只有转变思维方式,依据大数据的观念,应用定量研究的方法(用数学的方法研究地质问题)才能将其充分地挖掘出来。

关键词：大数据物化探信息定量预测模型找矿靶区

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Guidelines for Diagnosis and Treatment of Atopic Dermatitis in China(2020)#

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International Journal of Dermatology and Venereology 2021年第1期4卷 1-9页

作者： Xu Yao Zhi-Qiang Song wei Li Yun-Sheng Liang yan zhao Hua Cao Tao Chen Xue Chen Ai-Ping Feng Song-Mei Geng Heng Gu Shu-Ping Guo yan-Ling He Ye-Hong Kuang Chun-Ying Li xiao-Hong Li Zheng-xiao Li Jun-Qin Liang Hong-Ye Liu Ling-Ling Liu Yu-Mei Liu Zhi Liu Hai Long Qian-Jin Lu yan Lu xiao-Qun Luo xiao-yan Lv Lin Ma Zhu Shen Xin Shi Zhong-Xiang Shi Xiang-yang Su qing Sun Jian-Ping Tang Ao-Xue wang Hui-Ping wang Jian-Qin wang ming-Yue wang Zai-Xing wang Yu-Min Xia Ting xiao Zhi-Qiang Xie Huan Xing Ying Xiong Zi-Gang Xu Bin yang Zhi-Rong Yao Jian-Bin Yu Nan Yu Kang Zeng Jian-Zhong zhang Jun-Ling zhang Hua zhao Zuo-Tao zhao wei Zhu Ying-Hua Zhu Ying Zou Atopic Dermatitis Working Group,Immunology Group,Chinese Society of Dermatology Hospital for Skin Diseases(Institute of Dermatology) Chinese Academy of Medical SciencesNanjingJiangsu 210042China Southwest Hospital of Military Medical University Chongqing 400038China Huashan Hospital Affiliated with Fudan UniversityShanghai 200040China Dermatology Hospital of Southern Medical University GuangzhouGuangdong 510091China Peking University People’s Hospital Beijing 100044China Ruijin Hospital Affiliated with Shanghai Jiaotong UniversityShanghai 310000China Chengdu Second People’s Hospital ChengduSichuan 610017China Union Hospital Affiliated with Tongji Medical College of Huazhong University of Science and Technology WuhanHubei 430022China The Second Affiliated Hospital of Xi’an Jiaotong University Xi’anShaanxi 710004China First Hospital of Shanxi Medical University TaiyuanShanxi 030012China Beijing Chao-yang Hospital Capital Medical UniversityBeijing 100027China Xiangya Hospital Central South UniversityChangshaHunan 410008China Xijing Hospital Fourth Military Medical UniversityXi’anShaanxi 710032China The First Affiliated Hospital of Zhengzhou University ZhengzhouHenan 450052China People’s Hospital of Xinjiang Uygur Autonomous Region WulumuqiXinjiang 830001China Peking University First Hospital Beijing 100034China Guangzhou Institute of Dermatology GuangzhouGuangdong 510095China The Affiliated Hospital of Guizhou Medical University GuiyangGuizhou 550004China The Second Xiangya Hospital of Central South University ChangshaHunan 410011China The First Affiliated Hospital of Nanjing Medical University NanjingJiangsu 210029China West China Hospital Sichuan UniversityChengduSichuan 610041China Beijing Children’s Hospital Capital Medical UniversityBeijing 100045China Sichuan Academy of Medical Sciences&Sichuan Provincial People’s Hospital ChengduSichuan 610072China The Second Affiliated Hospital of Soochow University SuzhouJiangsu 215004China Shandong Provincial Dermatology Hospital JinanShandong 250022China The Third Affiliated Hospital of Sun Yat-sen U

Atopic dermatitis(AD)is a common disease clinically characterized by chronic recurrent eczematous lesions,dry skin,and *** can negatively impact patients’quality of *** prevalence of AD in China has been increasing during the past few *** on the most recent advances in the treatment of AD,we updated the 2014 version of the Guidelines for Diagnosis and Treatment of Atopic Dermatitis in China regarding the definition,epidemiology,pathogenesis,clinical classification,diagnosis,prevention,and treatment of AD.

关键词： atopic dermatitis diagnosis therapy guideline

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Follow-up of 3-to 24-month on COVID-19 with Pulmonary Tuberculosis Survivors after Discharge:Results from a Prospective,Multi-center Study

Follow-up of 3-to 24-month on COVID-19 with Pulmonary Tuberc...

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中国防痨协会2023年第34届全国学术大会暨结核病诊防治新技术推广应用论坛

作者： wang Jing Ya ZONG Xing Yu WU Gui Hui QI Yuan Lin LI Hui Zhen JI Xin Yu TONG Lin zhang Lei yang ming Bo yang Pu Ye LI Ji Ke xiao Fu Rong zhang Lin Song HU Yun Hong LIU Hong De XU Shou Fang SUN Sheng WU wei MAO Ya LI Min qing HOU Hao Huau GONG zhao Yuan GUO yang JIAO Li Wen QIN Jin wang Ding Yi wang Fang GUAN Li LIN Gang wang yan Ping SHI Nan Nan MA yan

Objective Coronavirus disease 2019(COVID-19) and tuberculosis(TB) are major public health and social issues *** long-term follow-up of COVID-19 with pulmonary TB(PTB) survivors after discharge is *** study aimed to comprehensively describe clinical outcomes,including sequela and recurrence at 3,12,and 24 months after discharge,among COVID-19 with PTB *** From January 22,2020,to May 6,2022,with a follow-up by August 26,2022,a prospective,multicenter follow-up study was conducted on COVID-19 with PTB survivors after discharge in 13 hospitals from four provinces in *** outcomes,including sequela,recurrence of COVID-19,and PTB survivors,were collected via telephone and face-to-face interviews at 3,12,and 24 months after *** Thirty-two COVID-19 with PTB survivors were *** median age was 52(45,59) years,and 23(71.9%) were *** them,nearly two-thirds(62.5%) of the survivors were moderate,three(9.4%) were severe,and more than half(59.4%) had at least one comorbidity(PTB excluded).The proportion of COVID-19 survivors with at least one sequela symptom decreased from 40.6% at 3 months to 15.8% at 24 months,with anxiety having a higher proportion over a *** and amnesia recovered at the 12-month follow-up,while anxiety,fatigue,and trouble sleeping remained after 24 ***,one(3.1%) case presented two recurrences of PTB and no re-positive COVID-19 during the follow-up *** The proportion of long symptoms in COVID-19 with PTB survivors decreased over time,while nearly one in six still experience persistent symptoms with a higher proportion of *** recurrence of PTB and the psychological support of COVID-19 with PTB after discharge require more attention.

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成都卒中登记方法及3123例患者基本特征和功能结局

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中华神经科杂志 2011年第12期44卷 826-831页

作者：郝子龙刘鸣李伟谭燕张月辉吴丽娥赵晓玲杨杰王清芳谈颂阳清伟吴波王丽春四川大学华西医院神经内科脑血管病临床研究中心成都610041

目的探讨卒中登记方法、了解卒中患者基本特征和功能结局。方法前瞻性、连续性登记自2002年3月1日起在四川大学华西医院神经内科住院的卒中患者。由统一培训的专科医师填写卒中登记表，登记患者临床特点、住院诊治情况，并随访各时点结... 详细信息

目的探讨卒中登记方法、了解卒中患者基本特征和功能结局。方法前瞻性、连续性登记自2002年3月1日起在四川大学华西医院神经内科住院的卒中患者。由统一培训的专科医师填写卒中登记表，登记患者临床特点、住院诊治情况，并随访各时点结局（发病后7d，1、3、6和12个月末的死亡和残疾）。结果纳入自2002年3月1日至2006年8月31日连续性登记的卒中患者共3123例。其中65．5％来自城区，34．5％来自农村。年龄14～98（63．05±17．98）岁，男性占60．3％，住院期间完成头颅CT和（或）MRI者占97％（3028／3123）。2002年3月至2004年9月纳入各类卒中患者共1804例。其中缺血性卒中62．1％（1120／1804），脑出血28．4％（513／1804），蛛网膜下腔出血4．0％（72／1804），TIA5．5％（99／1804）。2004年10月后未纳入蛛网膜下腔出血和TIA患者。入院时中位NIHSS评分脑出血患者8（3—15）分，脑梗死5（2～10）分。糖尿病（OR=2．427，95％CI1．811～3．253，P=0．000）、房颤（OR=6．121，95％CI3．535～10．60，P=0．000）、冠心病（OR=4．144，95％CI 2．944—5．832，P=0．000）、TIA史（OR=4．342，95％CI 1．726—10．92，P=0．001）发生比例脑梗死组高于脑出血组，而饮酒史脑梗死组低于脑出血组（OR=0．740，95％C10．611—0．896，P=0．002）。缺血性卒中患者溶栓占0．9％（20例），抗血小板治疗83．0％，甘露醇23．5％，神经保护剂（胞二磷胆碱）68．1％，中成药89．7％。7d和1个月病死率脑出血组分别为10．7％和13．9％，脑梗死组分别为3．0％和5．2％。3、6及12个月死亡或残疾率脑出血组分别为40．4％、40．3％和38．9％；脑梗死组分别为37．1％、35．0％和33．4％。结论本研究是国内目前报告的最大样本、最长时间的前瞻性连续性单中心卒中登记项目，提供了深入研究卒中临床特点的重要平台；本组患者病情偏轻，近期病死率及远期病死或残疾率低于国外，中国卒中防治的干预性临床试验设计廊注意考虑这些特点。

关键词：卒中登记前瞻性研究

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Consensus statement on layout and delivery of automatic external defibrillator in China

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Journal of Hainan Medical University 2020年第15期26卷 18-23页

作者： Yu Cao Song Chen yan-Fen Chai xiao-Hui Chen Yu-Guo Chen Shao-Wen Cheng Wen-wei Cheng Bang-Han Ding yang Deng Jie Fu Bang-Jiang Fang Mai-Ying Fan Li Gui Ping Gong wei Guo Shu-Bin Guo Liang Huang Ji-Yuan Han Zhong Ji Xian-Fei Ji Xin-Cai Ji Hong-Xu Jin Xin-Jun Jiang wang-Xiang Jiang Jia-Liang Liu xiao-Ran Liu Zhi Liu Chuan-Zhu Lv Feng Lu Tan-Shi Li Xin Li Yong Li Shang-Lun Li Shuang-ming Li xiao-Gang Li Bao-Jun Li Pei-Wu Li Chun-Sheng Li Zhi-Jun Li Chang-Luo Li Xiang-Min Li Yin-Ping Li Zong-Jun Lu Zu-Xun Lu Zhong-Qiu Lu Zhi-Qian Luo xiao-Xing Liao Jian-Bo Lei Tao Ma Yu Ma Yue-Feng Ma qing-Bian Ma Lin-Hao Ma Jun-Qi Ma Shi-Nan Nie Jie-Miao Ou-yang Peng Peng Qiao Pei Shu-ming Pan Guo-Zhong qing Li-Jie Qin Wu-Ying Qiao Fei Shao wei Song Xing-Yue Song Zhen-Ju Song Rong-Ju Sun De-Ya Shang Du-Juan Sha Gui-Lan Tao Guo-Gang Tian Ying-Ping Tian Jian-Guang Tian Chao-yang Tong Zi-Ren Tang Meng-Xiong Tang Guo-Ping Wu Zhi Wan Tao wang Xin wang Peng wang Zhong wang Tong wang Ri-Xing wang Yi-Xin wang xiao-Dan wang Ling Wu wei wei Hua Xiang Feng Xu Jun Xu Jie Xu Miao-Rong Xie Shuo-Gui Xu Tie Xu Feng Yu Wen Yi Li-Shan yang Shi-Jiao yan Jin-Jian Yao Shou-Chun yan Xue-Zhong Yu Xian-Zhi Ye Xian-Liang yan Fu-Bing Zhou Rong-Bin Zhou ming Zhou Qiang Zhou Jin Zhou Ping Zhou Chang-Ju Zhu Hua-Dong Zhu Ji-Hong Zhu Hong zhang Mao zhang Hua zhang Na zhang Guo-Qiang zhang Guo-Xiu zhang Jin-Song zhang Wen-Wu zhang Wen-Zhong zhang Jian-Feng zhang Yi-Min Zhu Jun Zeng Yuan Zheng Zhi-Jie Zheng Shen zhao yan zhao Min zhao Bin zhao xiao-Dong zhao xiao-Jing zhao Hong-Ke Zeng Sheng-Qiang Zou The Chinese Society of Emergency Medicine Research Unit of Island Emergency Medicine Chinese Academy of Medical SciencesHainan Medical University Key Laboratory of Emergency and Trauma of Ministry of Education Hainan Medical UniversityHaikouHainanChina Emergency and Trauma College Hainan Medical UniversityHaikouHainanChina Department of Emergency Hainan Clinical Research Center for Acute and Critical DiseasesThe Second Affiliated Hospital of Hainan Medical UniversityHaikouHainanChina Key Laboratory of Hainan Trauma and Disaster Rescue Key Laboratory of Trauma of Hainan Medical University

*** Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac *** is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].

关键词： cardiac death respiratory

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CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen mingjun Chen mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen wei Chen Xiang Chen xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho ming-Chung Chu xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui xiaohao Cui zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

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Small P values may not yield robust findings:an example using REST-meta-PD

引用

Science Bulletin 2021年第21期66卷 2148-2152,M0003页

作者： Xi-Ze Jia Na zhao Hao-ming Dong Jia-wei Sun Marek Barton Roxana Burciu Nicolas Carrière Antonio Cerasa Bo-Yu Chen Jun Chen Stephen Coombes Luc Defebvre Christine Delmaire Kathy Dujardin Fabrizio Esposito Guo-Guang Fan Federica Di Nardo Yi-Xuan Feng Brett W.Fling Saurabh Garg Moran Gilat Martin Gorges Shu-Leong Ho Fay BHorak xiao Hu xiao-Fei Hu biao Huang Pei-Yu Huang Ze-Juan Jia Christina Jones Jan Kassubek Lenka Krajcovicova Ajay Kurani Jing Li qing Li Ai-Ping Liu Bo Liu Hu Liu wei-Guo Liu Renaud Lopes Yu-Ting Lou wei Luo Tara Madhyastha Ni-Ni Mao Grainne McAlonan Martin J.McKeown Shirley Pang Andrea Quattrone Irena Rektorova Alessia Sarica Hui-Fang Shang James M.Shine Priyank Shukla Tomas Slavicek xiao-Peng Song Gioacchino Tedeschi Alessandro Tessitore David Vaillancourt Jian wang Jue wang Z.Jane wang Lu-qing wei Xia Wu xiao-Jun Xu Lei yan Jing yang Wan-Qun yang Nai-Lin Yao De-Long zhang Jiu-Quan zhang Min-ming zhang yan-Ling zhang Cai-Hong Zhou Chao-Gan yan Xi-Nian Zuo Mark Hallett Tao Wu Yu-Feng Zang Center for Cognition and Brain Disorders the Affiliated HospitalHangzhou Normal UniversityHangzhou 310015China Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments Hangzhou 311121China National Basic Science Data Center Beijing 100190China State Key Laboratory of Cognitive Neuroscience and Learning&McGovern Institute for Brain Research Beijing Normal UniversityBeijing 100875China School of Information and Electronics Technology Jiamusi UniversityJiamusi 154007China Neuroscience Program Central European Institute of TechnologyCEITECMasaryk UniversityBrno 62500Czech Republic Department of Applied Physiology and Kinesiology University of FloridaGainesville FL 32611USA Univ.Lille InsermCHU LilleU1172-LilNCog-Lille Neuroscience&CognitionLille F-59000France The Institute for Biomedical Research and Innovation National Research CouncilMangone CS 87050Italy Department of Radiology The First Affiliated Hospital of China Medical UniversityShenyang 110001China Department of Radiology Guangdong Provincial Hospital of Chinese MedicineGuangzhou 510120China Department of Medicine Surgery and DentistryScuola Medica SalernitanaUniversity of SalernoFiscianoSA 132-84084Italy Department of Advanced Medical and Surgery Sciences University of Campania“Luigi Vanvitelli”Caserta 81100Italy Eye Center of the 2nd Affiliated Hospital Medical College of Zhejiang UniversityHangzhou 310020China Zhejiang Provincial Key Lab of Ophthalmology Hangzhou 310020China Department of Health and Exercise Science Colorado State UniversityFort Collins CO 80523USA Pacific Parkinson’s Research Centre University of British ColumbiaVancouver BC V6E 2M6Canada Department of Medicine(Neurology)University of British Columbia Vancouver BC V6T 1B7Canada Brain and Mind Center The University of SydneySydney NSW 2006Australia Department of Neurology Ulm UniversityUlm 89081Germany Division of Neurology Department of MedicineQueen Mary HospitalUniversity of Hong KongHong Kong 999077China Department of

Thousands of resting state functional magnetic resonance imaging(RS-f MRI)articles have been published on brain *** precise localization of abnormal brain activity,a voxel-level comparison is *** of the large number of voxels in the brain,multiple comparison correction(MCC)must be performed to reduce false positive rates,and a smaller P value(usually including either liberal or stringent MCC)is widely recommended[1].

关键词：帕金森病 precise correction

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