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Coupled Responses of Sewol,Twin Barges and Slings During Salvage

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China Ocean Engineering 2018年第2期32卷 226-235页

作者： YAO Zong wang wei-ping JIANG Yan CHEN Shi-hai Shanghai Salvage Company Shanghai 200090China

Korean Sewol is successfully lifted up with the strand jack system based on twin barges. During the salvage operation, two barges and Sewol encounter offshore environmental conditions of wave, current and wind. It is inevitable that the relative motions among the three bodies are coupled with the sling tensions, which may cause big dynamic loads for the lifting system. During the project engineering phase and the site operation, it is necessary to build up a simulation model that can precisely generate the coupled responses in order to define a suitable weather window and monitor risks for the salvage operation. A special method for calculating multibody coupled responses is introduced into Sewol salvage project. Each body’s hydrodynamic force and moment in multibody configuration is calculated in the way that one body is treated as freely moving in space, while other bodies are set as fixed *** hydrodynamic force and moment are then applied into a numerical simulation model with some calibration coefficients being inserted. These coefficients are calibrated with the model test results. The simulation model built up this way can predict coupled responses with the similar accuracy as the model test and full scale measurement,and particularly generate multibody shielding effects. Site measured responses and the responses only resulted from from the simulation keep project management simultaneously to judge risks of each salvage stage, which are important for success of Sewol salvage.

关键词： salvage lifting barge coupled response numerical simulation model test site measurement

New classification of the anatomic variations of cystic artery during laparoscopic cholecystectomy

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World Journal of Gastroenterology 2007年第42期13卷 5629-5634页

作者： You-Ming Ding Bin wang wei-Xing wang ping wang Ji-Shen Yan Department of Hepatobiliary & Laparoscopic Surgery Renmin Hospital of Wuhan University Wuhan 430060 HubeiProvince China

AIM： To investigate the anatomic variations in the cystic artery by laparoscopy, and to provide a new classification system for the guidance of laparoscopic ***： Six hundred patients treated with laparoscopic cholecystectomy from June 2005 to May 2006 were studied retrospectively, The laparoscope of 30° （Stryker, American） was applied, Anatomic structures of cystic artery and conditions of Calot＇s triangle under laparoscope were recorded respectively,RESULTS： Laparoscopy has revealed there are many anatomic variations of the cystic artery that occur frequently. Based on our experience with 600 laparoscopic cholecystectomies, we present a new classification of anatomic variations of the cystic artery, which can be divided into three groups：（1） Calot＇s triangle type, found in 513 patients （85.5%）; （2） outside Calot＇s triangle, found in 78 patients （13%）; （3） compound type, observed in 9 patients （1.5%）.CONCLUSION： Our classification of the anatomic variations of the cystic artery uncontrollable cystic artery extrahepatic bile duct injury. will be useful for decreasing hemorrhage, and avoiding extrahepatic bile duct injury.

关键词： Cystic artery Laparoscopic cholecystectomy Bile duct injury Calot's triangle

The prevalence of azoospermia factor microdeletion on the Y chromosome of Chinese infertile men detected by multi-analyte suspension array technology

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Asian Journal of Andrology 2008年第6期10卷 873-881页

作者： Yi-Jian Zhu Si-Yao Liu Huan wang ping wei Xian-ping Ding Institute of Medical Genetics Key Laboratory of Bio-resources and Eco-environment Ministry of Education College of Life Science Sichuan University Chengdu 610064 China

Aim： To develop a high-throughput multiplex, fast and simple assay to scan azoospermia factor （AZF） region microdeletions on the Y chromosome and establish the prevalence of Y chromosomal microdeletions in Chinese infertile males with azoospermia or oligozoospermia. Methods： In total, 178 infertile patients with azoospermia （nonobstructed）, 134 infertile patients with oligozoospermia as well as 40 fertile man controls were included in the present study. The samples were screened for AZF microdeletion using optimized multi-analyte suspension array （MASA） technology. Results： Of the 312 patients, 36 （11.5%） were found to have deletions in the AZF region. The rnicrodeletion frequency was 14% （25/178） in the azoospermia group and 8.2% （11/134） in the oligospermia group. Among 36 patients with microdeletions, 19 had deletions in the AZFc region, seven had deletions in AZFa and six had deletions in AZFb. In addition, four patients had both AZFb and AZFc deletions. No deletion in the AZF region was found in the 40 fertile controls. Conclusion： There is a high prevalence of Y chromosomal microdeletions in Chinese infertile males with azoospermia or oligozoospermia. The MASA technology, which has been established in the present study, provides a sensitive and high-throughput method for detecting the deletion of the Y chromosome. And the results suggest that genetic screening should be advised to infertile men before starting assisted reproductive treatments.

关键词： Y chromosome microdeletion azoospermia factor male infertility multi-analyte suspension array (MASA)

Convenient synthesis of (4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane

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Chinese Chemical Letters 2007年第7期18卷 783-784页

作者： Jian Jiang De Cai wang wei Lin ping Kai Ouyang College of Life Science and Pharmaceutical Engineering Nanjing University of Technology Nanjing 210009 China

A convenient approach for the preparation of （4R,5R）-4,5-bis（aminomethyl）-2-isopropyl-l,3-dioxolane is described. The target compound via two steps is synthesized from diethyl-2,3-O-isobutylidene-D-tartrate, throu... 详细信息

关键词： Heptaplatin Aminomethyl Intermediate Anticancer drug

Effect of La on Partial Oxidation of Ethanol to Hydrogen over Ni/Fe Catalysts

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Chemical Research in Chinese Universities 2003年第2期19卷 206-210页

作者： wang wei ping wang Zhi fei DING Yan and LU Gong xuan State Key Laboratory for Oxo Synthesis and Selective Oxidation Lanzhou Institute of Chemical PhysicsChinese Academy of SciencesLanzhou 730000P.R.China

The partial oxidation of ethanol to hydrogen was investigated over Ni/Fe/La catalysts prepared by the co precipitation method. The effects of introduction of La promoter and the reaction temperature on the catalytic performance were studied. It was found that the introduction of La into Ni/Fe catalysts is helpful to increase the selectivity to hydrogen and the stability of the catalysts. The results of XRD and XPS characterization show that the structure of the catalyst was changed during the reaction. The existence of LaFeO 3 species is possibly the main reason of the increase of the catalyst stability.

关键词： Ethanol Ni/Fe/La catalyst Partial oxidation Production of hydrogen

The HD-Zip transcription factor GhHB12 represses plant height by regulating the auxin signaling in cotton

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Journal of Integrative Agriculture 2023年第7期22卷 2015-2024页

作者： LIU Yan wang wei-ping ZHANG Lin ZHU Long-fu ZHANG Xian-long HE Xin College of Agronomy Hunan Agricultural UniversityChangsha 410128P.R.China National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhan 430070P.R.China

Upland cotton(Gossypium hirsutum L.)is the most important natural textile fiber crop *** height(PH)is a significant component of plant architecture,strongly influencing crop cultivation patterns,overall yield,and economic ***,cotton genes regulating plant height have not been fully ***,an HD-Zip gene(GhHB12)was isolated and characterized in cotton,which regulates the abiotic and biotic stress responses and the growth and development *** this study,we showed that GhHB12 was induced by ***,overexpression of GhHB12 induces the expression of HY5,ATH1,and HAT4,represses the spatial-temporal distribution,polar transport,and signaling of auxin,alters the expression of genes involved in cell wall expansion,and restrains the plant height in *** results suggest a role of GhHB12 in regulating cotton plant height,which could be achieved by affecting the auxin signaling and cell wall expansion.

关键词： cotton GhHB12 plant height auxin cell wall HD-Zip

Chemical fingerprinting of Su-He-Xiang-Wan and attribution of major characteristic peaks for its quality control by GC-MS

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Journal of Central South University 2013年第8期20卷 2115-2123页

作者： wang wei-ping LIN Juan ZHANG Liang-xiao ZHANG Ming-yue LIANG Yi-zeng Research Center of Modernization of Chinese Herbal Medicine College of Chemistry and Chemical Engineering Central South University Changsha 410083 China Xinjiang Uygur Autonomous Region Institute for Food and Drug Control Urumqi 830004 China Oilcrops Research Institute Chinese Academy of Agricultural Sciences Wuhan 430062 China

A simple and facile gas chromatography-mass spectrometer （GC-MS） fingerprint of Su-He-Xiang-Wan （SHXW） was developed, the similarity analysis was conducted, and attribution of the major characteristic peaks was identified for SHXW quality control. GC-MS analysis was performed on a QP2010 instrument （Shimadzu, Japan） equipped with a capillary column of RTX-5MS. The column temperature was initiated at 50℃, held for 5 min, increased at the rate of 3 ℃/min to 120 ℃, held for 2 min, and then increased at the rate of 4 ℃/min to 220℃, held for 10 min. Helium carrier gas was used at a constant flow rate of 1.3 mL/min. Mass conditions were ionization voltage, 70 eV; injector temperature, 250℃; ion source temperature, 250 ℃; splitting ratio, 30：1; full scan mode in the 40-500 Da mass ranges with rate of 0.2 s per scan. Attribution of the major characteristic peaks was identified for SHXW by comparing the chemical standards, references of Chinese herbal medicines and the negative controls of prescription samples （NC） of SHXW. With the help of the temperature-programmed retention indices （PTRIs） used together with mass spectra and chemical standards, 25 major characteristic peaks have been identified. Nine volatile medicinal materials were identified in the prescription of SHXW by attributing to the 27 major characteristic peaks. The results demonstrate that the proposed method is a powerful approach to quality control of complex herbal medicines.

关键词： chromatographic fingerprint attribution analysis quality control herbal medicines complex prescription

Effects of Combination of 1,25(OH)_(2)D_(3) and TLR-4 Inhibitor on the Damage to HaCaT Cells Caused by UVB Irradiation

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Biomedical and Environmental Sciences 2022年第11期35卷 1051-1062页

作者： CHEN Peng ZHUANG Chuan Ning CUI Jia Jing wang ping wei LIU Dong Ge YAN Shu Qi ZHOU Li Ting REN Shu ping Department of Pediatrics the Second Hospital of Jilin UniversityChangchun 130041JilinChina Department of Occupational and Environmental Health School of Public HealthJilin UniversityChangchun 130021JilinChina

Objective Vitamin D and Toll-like receptor-4(TLR-4)inhibition are involved in the protection of *** effects of combination of 1,25(OH)_(2)D_(3) and TLR-4 inhibitor on the protection of keratinocytes against ultraviolet radiation B(UVB)irradiation remain *** study was undertaken to explore the effects of combination of 1,25(OH)_(2)D_(3) and TAK-242(TLR-4 inhibitor)on the damage to HaCaT cells caused by UVB *** In vitro,HaCaT cells were treated with 1,25(OH)_(2)D_(3) or/and TAK-242 prior to UVB irradiation at the intensity of 20 mJ/cm^(2),then the production of reactive oxygen species(ROS),cell migration,apoptosis of cells,and the expression of oxidative stress,endoplasmic reticulum stress,and apoptosis related proteins were *** Compared with the HaCaT cells treated with 1,25(OH)_(2)D_(3) or TAK-242,the cells treated with both 1,25(OH)_(2)D_(3) and TAK-242 showed,1)significantly lower production of ROS(P<0.05);2)significantly less apoptosis of HaCaT cells(P<0.05);3)significantly lower expression of NF-κB,Caspase-8,Cyto-C,Caspase-3(P<0.05).Conclusion The combination of 1,25(OH)_(2)D_(3) and TAK-242 could produce a better protection for HaCaT cells via inhibiting the oxidative stress,endoplasmic reticulum stress and apoptosis than 1,25(OH)_(2)D_(3) or TAK-242 alone.

关键词： UVB 1,25(OH)_(2)D_(3) Toll-like receptor 4 HaCaT cell Combined effects

Noninfectious Fever Following Aortic Surgery:Incidence,Risk Factors,and Outcomes

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Chinese Medical Sciences Journal 2009年第4期24卷 213-219页

作者： Yun-tai Yao Li-huan Li Qian Lei Lei Chen wei-peng wang wei-ping Chen Department of Anesthesiology Fuwai Cardiovascular Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100037 China

Objective To determine the incidence, course, potential risk factors, and outcomes of noninfectious fever developed in patients after aortic surgery. Methods Patients who received operation for aortic aneurysm or dissection in our center from January 2006 to January 2008 were reviewed. Patients who met one of the following criteria were excluded： having a known source of infection during hospitalization; having a preoperative oral temperature greater than or equal to 38.0℃; undertaking emergency surgery; having incomplete data. Univariate analysis was performed in patients with noninfectious postoperative fever and those without, with respect to demographics, intraoperative data, etc. Risk factors for postoperative fever were considered for the muhivariate logistic regression model if they had a P value less than 0.10 in the univariate analysis. Results Totally 463 patients undergoing aortic surgery were enrolled for full review. Among them, 345 （74.5%） patients had noninfectious postoperative fever, the other 118 （25.5%） patients didn＇t develop postoperative fever. Univariate analysis demonstrated that several risk factors were associated with the development of noninfectious postoperative fever, including weight, surgical procedure, minimum intraoperative bladder temperature, temperature upon intensive care unit （ICU） admission, discharge, and during ICU stay, as well as blood transfusion. In a further multivariate analysis, surgical site of thoracic and thoracoabdominal aorta （odds ratio： 4.861; 95% confidence interval： 3.029-5.801; P=0.004）, lower minimum intraoperative bladder temperature （odds ratio： 1.117; 95% confidence interval： 1.01-1.24; P=0.04）, and higher temperature on admission to the ICU （odds ratio： 2.57; 95% confidence interval： 1.28-5.18; P=0.008） were found to be significant predictors for noninfectious postoperative fever. No difference was found between the febrile and afebrile patients with regard to postoperative hospitalization duration （P

关键词： fever noninfectious aortic surgery