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Science China(Technological Sciences) 2024年第6期67卷 1893-1906页

作者： AN Kai wang ZhenGuo HUANG wei Hypersonic Technology Laboratory National University of Defense TechnologyChangsha410073China

We propose an adaptive learning-based optimal control scheme for height-velocity control models considering model uncertainties and external disturbances of hypersonic winged-cone *** longitudinal nonlinear model is first established and transformed into the control-oriented error equations,and the control scheme is organized by a steady-compensation *** overcome and eliminate the impact of model uncertainties and external disturbances,an adaptive radial basis function neural network(RBFNN)is designed by a q-gradient *** the height-velocity error system with estimated uncertainties into account,the adaptive learning-based optimal tracking control(ALOTC)scheme is proposed by combining the critic-only adaptive dynamic programming(ADP)framework and parameter optimization of system settling ***,a novel weight update law is proposed to satisfy the online iteration requirements,and the algorithm convergence and closedloop stability are discussed by the Lyapunov ***,four simulation cases are provided to prove the effectiveness,accuracy,and robustness of the proposed scheme for the hypersonic longitudinal control system.

关键词： optimal tracking control adaptive dynamic programming RBFNN hypersonic vehicle

OnFractional(g,f,n′,m)-Critical Covered Graphs

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Journal of the Operations Research Society of China 2024年第2期12卷 446-460页

作者： wei Gao wei-Fan wang School of Information Science and Technology Yunnan Normal UniversityKunming 650500YunnanChina Department of Mathematics Zhejiang Normal UniversityJinhua 321004ZhejiangChina

The main contribution in this article is threefold:(1)we show the necessary and sufficient condition for graphs to be fractional(g,f)-covered which can be expressed in different forms,and extended to fractional(g,f,m)-covered graphs;(2)the concept of fractional-critical covered graph is put forward and its necessary and sufficient condition is given;(3)we present the degree condition for a graph to be fractional(g,f,n′,m)-critical covered,and show that degree bound is sharp when m is ***,the related result in fractional(a,b,n′,m)-critical covered setting is also verified.

关键词： Network Fractional factor Data transmission Fractional covered graph Fractional critical covered graph

Impact of frailty on outcomes of elderly patients undergoing percutaneous coronary intervention: A systematic review and metaanalysis

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World Journal of Clinical Cases 2024年第1期12卷 107-118页

作者： shi-shi wang wang-Hao Liu Department of Emergency Medicine Huzhou Third Municipal HospitalThe Affiliated Hospital of Huzhou UniversityHuzhou 313000Zhejiang ProvinceChina Department of Geriatrics Huzhou Third Municipal Hospitalthe Affiliated Hospital of Huzhou UniversityHuzhou 313000Zhejiang ProvinceChina

BACKGROUND Frailty is a common condition in elderly patients who receive percutaneous coronary intervention(PCI).However,how frailty affects clinical outcomes in this group is *** To assess the link between frailty and the outcomes,such as in-hospital complic-ations,post-procedural complications,and mortality,in elderly patients *** The PubMed/MEDLINE,EMBASE,Cochrane Library,and Web of Science databases were screened for publications up to August *** primary outcomes assessed were in-hospital and all-cause mortality,major adverse cardiovascular events(MACEs),and major *** Newcastle-Ottawa Scale was used for quality *** Twenty-one studies with 739693 elderly patients undergoing PCI were *** was consistently associated with adverse *** patients had significantly higher risks of in-hospital mortality[risk ratio:3.45,95%confidence interval(95%CI):1.90-6.25],all-cause mortality[hazard ratio(HR):2.08,95%CI:1.78-2.43],MACEs(HR:2.92,95%CI:1.85-4.60),and major bleeding(HR:4.60,95%CI:2.89-7.32)compared to non-frail *** Frailty is a pivotal determinant in the prediction of risk of mortality,development of MACEs,and major bleeding in elderly individuals undergoing percutaneous coronary intervention.

关键词： Frailty Elderly Percutaneous coronary intervention Systematic review Meta-analysis

An Efficient Probe for Bacterial Nitroreductase Imaging and Detection Based on NanoLuc-Furimazine Bioluminescent Pair

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Chinese Journal of Chemistry 2024年第12期42卷 1373-1380页

作者： Ximeng shi Yumeng wang Jiaoyang Yu Yating Yang Zecheng Jin Hanghang wang Dalei Wu wei Chen Jianming Guo Yinan Zhang Jiangsu Key LaboratoryforFunctional Substances of Chinese Medicine School of PharmacyNanjing Universityof Chinese MedicineNanjingJiangsu210023China Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization School of PharmacyNanjing University of ChineseMedicineNanjingJiangsu210023China Clinical Research Center the Second Hospital of NanjingAffiliated Hospital to Nanjing University of Chinese MedicineNanjingJiangsu210003China Key Laboratory of Resources Biology and Biotechnology in Western China Ministry of EducationCollege of Life SciencesNorthwestUniversityXi'anShaanxi710069China Helmholtz International Lab State Key Laboratoryof Microbial TechnologyShandong UniversityQingdaoShandong 266237China

Comprehensive SummaryThe detection of critical endogenous species, such as bacteria in microenvironments in the body, requires better imaging tools for visualization and monitoring of biological events. Bioluminescence imaging is the most popular strategy for obtaining real-time in living cells and organisms. Herein, we introduced a nitroaryl group on the C-3 position and a hydroxy group at the C-6 phenyl ring on furimazine to report the first bioluminescent probe (7) based on NanoLuc-furimazine bioluminescent pair for the detection of nitroreductase in bacteria. The probe, which possessed up to 560-fold intensity increase with a low detection limit of 16 ng/mL of nitroreductase, has the most efficient uncage efficiency in comparison with other bioluminescent congeners, thus enabling highly selective and sensitive visualization of NTR activity in a panel of clinical priority pathogens. Additionally, imaging of the recombinant strain as well as the NTR from mouse feces indicated the potential of this probe in the application of different mouse disease models.

关键词： Nitroreductase NanoLuc-furimazine Biosensors Analytical methods Luminescence Imaging agents

Steady-state Voltage Security-constrained Optimal Frequency Control for Weak HVDC Sending-end AC Power Systems

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Journal of Modern Power Systems and Clean Energy 2024年第2期12卷 658-669页

作者： Qiangqiang wang Liangzhong Yao Jian Xu Yuping Zheng wei Li wei wang School of Electrical Engineering and Automation Wuhan UniversityWuhan 430072China Hubei Engineering and Technology Research Center for AC/DC Intelligent Distribution Network(Wuhan University) Wuhan 430072China State Key Laboratory of Smart Grid Protection and Control NARI Group Corporation(State Grid Electric Power Research Institute)Nanjing 211106China

Due to the fact that a high share of renewable energy sources(RESs)are connected to high-voltage direct current(HVDC)sending-end AC power systems,the voltage and frequency regulation capabilities of HVDC sending-end AC power systems have *** has resulted in potential system operating problems such as overvoltage and overfrequency,which occur simultaneously when block faults exist in the HVDC *** this study,a steady-state voltage security-constrained optimal frequency control method for weak HVDC sending-end AC power systems is *** integrated virtual inertia control of RESs is employed for system frequency *** dynamic reactive power compensation devices are utilized to control the voltage of all nodes meet voltage security ***,an optimization model that simultaneously considers the frequency and steady-state voltage security constraints for weak HVDC sending-end AC power systems is *** optimal control scheme with the minimum total cost of generation tripping and additional dynamic reactive power compensation required is obtained through the optimization *** are conducted on a modified IEEE 9-bus test system and practical Qing-Yu line commutated converter based HVDC(LCC-HVDC)sending-end AC power system to verify the effectiveness of the proposed method.

关键词： Renewable energy source(RES) high-voltage direct current(HVDC) AC power system optimal frequency control steady-state voltage security dynamic reactive power compensation

PEGylated graphene oxide-mediated stimulation of vascular endothelial cells and responsive release of PD-1/PD-L1 inhibitor for efficient chemo-immunotherapy against cancer Author links open overlay panel

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Particuology 2024年第8期91卷 280-290页

作者： Yan wang Feng Li Shuang wang Jiaqi Meng Xiao Zhang wei wei State Key Laboratory of Biochemical Engineering Institute of Process EngineeringChinese Academy of SciencesBeijing100190China Key Laboratory of Biopharmaceutical Preparation and Delivery Chinese Academy of SciencesBeijing100190China School of Chemical Engineering University of Chinese Academy of SciencesBeijing100049China

Immune checkpoint blockade(ICB)has emerged as a promising immunotherapeutic modality against cancer in the ***,only 10-30%of patients respond to ICB,primarily due to poor immunogenicity and insufficient T cell infiltration in solid ***,we presented an approach for high-performance cancer treatment using the programmed cell death protein-1 and programmed cell death ligand-1(PD-1/PD-L1)inhibitor(BMS-202)-loaded PEGylated graphene oxide(GPi).On the one hand,GPi dissociated tight junctions of vascular endothelial cells(VECs)in tumor,thus promoting the extravasation and intratumoral accumulation of liposomal doxorubicin(LipDox),which then effectively induced immunogenic cell death of tumor *** the other hand,GPi also stimulated VECs to upregulate the expression of cell-cell interaction molecules,such as intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1,which facilitated the infiltration of T cells in *** acting as a stimulator of VECs,GPi could exert responsive release of BMS-202 under the acidic tumor microenvironment and blockade PD-1/PD-L1 axis in ***,the alternating administration of GPi and LipDox effectively inhibited tumor growth in a 4T1 tumor model,providing a novel treatment mode for chemo-immunotherapy.

关键词： PEGylated graphene oxide Vascular endothelial cells Immune checkpoint blockade Immunogenic cell death Chemo-immunotherapy

Enhance the Performance of Directional Feature-based Palmprint Recognition by Directional Response Stability Measurement

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Machine Intelligence Research 2024年第3期21卷 597-614页

作者： Haitao wang wei Jia School of Computer Science and Information Engineering Hefei University of TechnologyHefei230009China

Palmprint recognition is an emerging biometrics technology that has attracted increasing attention in recent years. Many palmprint recognition methods have been proposed, including traditional methods and deep learning-based methods. Among the traditional methods, the methods based on directional features are mainstream because they have high recognition rates and are robust to illumination changes and small noises. However, to date, in these methods, the stability of the palmprint directional response has not been deeply studied. In this paper, we analyse the problem of directional response instability in palmprint recognition methods based on directional feature. We then propose a novel palmprint directional response stability measurement (DRSM) to judge the stability of the directional feature of each pixel. After filtering the palmprint image with the filter bank, we design DRSM according to the relationship between the maximum response value and other response values for each pixel. Using DRSM, we can judge those pixels with unstable directional response and use a specially designed encoding mode related to a specific method. We insert the DRSM mechanism into seven classical methods based on directional feature, and conduct many experiments on six public palmprint databases. The experimental results show that the DRSM mechanism can effectively improve the performance of these methods. In the field of palmprint recognition, this work is the first in-depth study on the stability of the palmprint directional response, so this paper has strong reference value for research on palmprint recognition methods based on directional features.

关键词： Biometrics palmprint recognition directional response stability directional coding-based methods directional feature

Constructing highly safe and long-life calcium ion batteries based on hydratedvanadium oxide cathodes featuring a pillar structure

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Rare Metals 2024年第6期43卷 2597-2612页

作者： Chun-Fang wang shi-wei Zhang Lan Huang Yuan-Min Zhu Feng Liu Jian-Chuan wang Li-Ming Tan Chun-Yi Zhi Cui-Ping Han Powder Metallurgy Research Institute Central South UniversityChangsha410083China Songshan Lake Materials Laboratory Dongguan 523808China Research Institute of Interdisciplinary Science and School of Materials Science and Engineering Dongguan University of TechnologyDongguan 523808China Department of Materials Science and Engineering City University of Hong KongHong Kong 999077China Faculty of Materials Science and Energy Engineering/Institute of Technology for Carbon Neutrality Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China

Calcium-ion batteries(CIBs)have generated intense interest due to the growing demand for safer,cheaper,and large-scale energy storage ***,their development is still in its infancy,owing to the lack of suitable cathodes for sustaining reversiblc Ca^(2+)intercalation/***,layered H_(2)V_(3)O_(8)(HVO)with Zn^(2+)pre-insertion(ZHVO)is reported as a high-rate and highly durable cathode material for *** existence of Zn^(2+)and H_(2)O pillars could expand the interlayer spacing up to 1.8 nm,which is favorable for the diffusion of bulky Ca^(2+).The formation of Zn-O bonds facilitates electron transfer and enhances electrical ***,the ZHVO cathode achieves superior capacity performance(213.9 mAh·g^(-1)at 0.2 A·g^(-1))and long lifespan(78.3%for 1,000 cycles at 5 A·g^(-1))compared to pristine *** functional theory(DFT)calculations revealed that Zn^(2+)moved during Ca^(2+)intercalation,thereby reducing the diffusion energy barrier and facilitating Ca^(2+)***,a safe aqueous calcium ion cell was successfully assembled.

关键词： Multivalent batteries Calcium-ion batteries Layered structure Vanadium oxide Cathode materials

Is the Cape Stone Forest in Shantou City formed by wave erosion? A comparison of the pedestal rocks on the coasts and the mountains of Queshi in eastern Guangdong, China

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Journal of Mountain Science 2024年第5期21卷 1447-1463页

作者： CHEN Min wang wei School of Geography South China Normal UniversityGuangzhou 510631China

Cape Stone Forest is a group of granite rock pillars(pedestal rocks) towering over shilin Lake, on the southern shore of Shantou Bay in eastern Guangdong, China. The rock pillars were previously identified as sea stacks because they have marine notch-like concave sidewalls at their base, and more importantly, the lake is immediately adjacent to the bay, which is exposed to the open sea. However, rock pillars similar in shape and size can also be found at the top of Queshi Mountain, which is only about 300 meters northwest of the lake and about 85 meters above sea level. Therefore, the marine origin of Cape Stone Forest is seriously questioned. In this study, 3D imagery and drone technology were used to collect data in the investigations without direct manual measurements in the water or on the mountain. It shows that the concave sidewalls of the rock pillars in the lake and on the mountains occur at different heights and are exposed to different directions, while a natural sea stack on Mayu Island at the mouth of Shantou Bay has a horizontal notch parallel to the sea level, although the granite rock of the sea stack is the same as that of the lake and the mountains. The eastern side of the island, where the sea stack is located, is exposed to the open sea but blocks large waves for the rock pillars in the lake. Therefore, the origin of Cape Stone Forest cannot be explained by wave-based mechanisms. The only satisfactory explanation that takes into account all the field evidence is that the narrow rock pillars of the lake and mountain were formed by chemical weathering that penetrated closely the spaced joints of the granite rock, and the notch-like concave sidewalls were formed by more effective chemical weathering at the base of the pillars.

关键词： Pedestal rock Granite Closely spaced joints Wave erosion Chemical weathering

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图书馆应当弘扬“智慧工匠精神”

图书馆论坛 2017年第3期37卷 51-56页

作者：王世伟上海社会科学院信息研究所

文章论述"工匠"的概念与"智慧工匠"的新理念,分析弘扬"智慧工匠精神"是图书馆迈向新一代智慧图书馆、进一步提升图书馆服务质量和图书馆提升文化软实力的需要。图书馆弘扬"智慧工匠精神",要注重践行敬业的社会主义核心价值观、谋划图书... 详细信息

文章论述"工匠"的概念与"智慧工匠"的新理念,分析弘扬"智慧工匠精神"是图书馆迈向新一代智慧图书馆、进一步提升图书馆服务质量和图书馆提升文化软实力的需要。图书馆弘扬"智慧工匠精神",要注重践行敬业的社会主义核心价值观、谋划图书馆发展的创新转型、融入网络智能技术。

关键词：工匠精神智慧工匠精神智慧图书馆图书馆服务图书馆文化软实力