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Computer Modeling in Engineering & Sciences 2019年第4期119卷 35-62页

作者： Andrew Lundberg pengtao Sun Cheng wang Chen-song Zhang Department of Mathematical Sciences University of NevadaLas Vegas4505 Maryland ParkwayLas VegasNV 89154USA School of Mathematical Sciences Tongji UniversityShanghaiChina LSEC&NCMIS Academy of Mathematics and System ScienceBeijingChina

The distributed Lagrange multiplier/fictitious domain(DLM/FD)-mixed finite element method is developed and analyzed in this paper for a transient Stokes interface problem with jump coefficients.The semi-and fully discrete DLM/FD-mixed finite element scheme are developed for the first time for this problem with a moving interface,where the arbitrary Lagrangian-Eulerian(ALE)technique is employed to deal with the moving and immersed subdomain.Stability and optimal convergence properties are obtained for both schemes.Numerical experiments are carried out for different scenarios of jump coefficients,and all theoretical results are validated.

关键词： Transient Stokes interface problem jump coefficients distributed Lagrange multiplier fictitious domain method mixed finite element an optimal error estimate stability

Nontoxic virus nanofibers improve the detection sensitivity for the anti-p53 antibody, a biomarker in cancer patients

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Nano Research 2015年第11期8卷 3562-3570页

作者： pengtao Pan Yicun wang Ye Zhu Xiang Gao Zhigang Ju Penghe Qiu Li wang Chuanbin Mao Institute of Genetics and Cytology School of Life Sciences Northeast Normal University 5268 Renmin Street Changchun 130024 China Department of Chemistry and Biochemistry Stephenson Life Sciences Research Center University of Oklahoma Norman Oklahoma 73019 USA

在浆液的 anti-p53 抗体的存在是为癌症的 biomarker。然而，它的高敏感察觉仍然是在癌症诊断的一个问题。处理这挑战，我们使用了 fd 噬菌体，对人安全的细菌特定的病毒 nanofiber 那能被以一种无差错的方式感染主人细菌大量生产，并... 详细信息

在浆液的 anti-p53 抗体的存在是为癌症的 biomarker。然而，它的高敏感察觉仍然是在癌症诊断的一个问题。处理这挑战，我们使用了 fd 噬菌体，对人安全的细菌特定的病毒 nanofiber 那能被以一种无差错的方式感染主人细菌大量生产，并且遗传上设计了它显示能够在它的方面墙上认出并且捕获 anti-p53 抗体的肽。我们作为一根俘获探针采用了结果的噬菌体 nanofibers 开发连接酶的 immunosorbent 试金(ELISA ) 的一个修改版本方法，称为的 phage-ELISA。我们为 anti-p53 抗体的察觉把它比作传统的 ELISA 方法， p53-ELISA，哪个使用 recombinant 捕获 anti-p53 的野类型的 p53 蛋白质抗体。我们使用了 phage-ELISA 与恶意的肿瘤的各种各样的类型在 316 个病人的一个试验性的组检测 anti-p53 抗体。我们发现 17.7% 的察觉率(56 个积极盒子) 被 phage-ELISA 完成，它为 p53-ELISA (65 个积极盒子) 比得上 20.6% 的察觉率。然而，当噬菌体和 p53 被联合为 phage/p53-ELISA 形成捕获抗体的探针时， 30.4% 的察觉率(96 个积极盒子) 被完成。我们的工作证明由于由噬菌体 nanofibers 和 p53 的 anti-p53 抗体的联合俘获， phage/p53-ELISA 与癌症的各种各样的类型在病人为 anti-p53 抗体完成了最高诊断的精确性和察觉效率。我们的工作建议那 nanofibers 和抗原的联合，哪个俘获抗体，能导致增加的察觉敏感，它为在生命科学，临床的药，和环境科学的应用是有用的。

关键词： p53基因抗体检测纳米纤维生物标志物癌症患者高灵敏度酶联免疫吸附法 ELISA方法

Hot deformation behavior of a novel bimetal consisting of BTW1 and Q345R characterized by processing maps

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Frontiers of Mechanical Engineering 2019年第4期14卷 489-495页

作者： pengtao LIU Lifeng MA Weitao JIA Tao wang Guanghui ZHAO College of Mechanical Engineering Taiyuan University of TechnologyTaiyuan 030024China Shanxi Provincial Key Laboratory of Metallurgical Equipment Design and Technology Taiyuan University of Science and TechnologyTaiyuan 030024China College of Mechanical Engineering Taiyuan University of Science and TechnologyTaiyuan 030024China

Only a few studies have been conducted on the flow behavior of the novel BTW1/Q345R bimetal,which is widely used in coal equipment.In this work,compression tests were conducted on BTW1/Q345R bimetal at a temperature range of 950°C–1200°C and strain rates of 0.05,0.5,5,and 15 s^−1 by using a Gleeble-3800 thermomechanical simulator.A constitutive equation was validated by referring to the Arrhenius equation during the characterization of hot workability.The computed apparent activation energy of the BTW1/Q345R bimetal was 360 kJ/mol,and processing maps under different strain conditions were drawn.Analysis of the stress-strain relationship revealed that work hardening exerted a dominant effect on the thermal deformation of the BTW1/Q345R bimetal.The processing maps predicted that the optimal processing interval will increase with strain.Results showed that thermal deformation of the BTW1/Q345R bimetal should proceed when the temperature range varies from 1182°C to 1200°C and the strain rate interval is from 4.2 to 15 s^−1.

关键词： BTW1/Q345R bimetal constitutive equation processing map work hardening

Fast Numerical Simulation of Two-Phase Transport Model in the Cathode of a Polymer Electrolyte Fuel Cell

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Communications in Computational Physics 2009年第6期6卷 49-71页

作者： pengtao Sun Guangri Xue Chaoyang wang Jinchao Xu Department of Mathematical Sciences University of NevadaLas Vegas4505 Maryland ParkwayLas VegasNV 89154USA Department of Mathematics The Pennsylvania State UniversityUniversity ParkPA 16802USA Departments of Mechanical Engineering and Materials Science and Engineering Electrochemical Engine Center(ECEC)The Pennsylvania State UniversityUniversity ParkPA 16802USA Laboratory of Mathematics and Applied Mathematics School of Mathematical SciencesPeking UniversityBeijing 100871China

In this paper,we apply streamline-diffusion and Galerkin-least-squares fi-nite element methods for 2D steady-state two-phase model in the cathode of polymer electrolyte fuel cell(PEFC)that contains a gas channel and a gas diffusion layer(GDL).This two-phase PEFC model is typically modeled by a modified Navier-Stokes equation for the mass and momentum,with Darcy’s drag as an additional source term in momentum for flows through GDL,and a discontinuous and degenerate convectiondiffusion equation for water concentration.Based on the mixed finite element method for the modified Navier-Stokes equation and standard finite element method for water equation,we design streamline-diffusion and Galerkin-least-squares to overcome the dominant convection arising from the gas channel.Meanwhile,we employ Kirchhoff transformation to deal with the discontinuous and degenerate diffusivity in water concentration.Numerical experiments demonstrate that our finite element methods,together with these numerical techniques,are able to get accurate physical solutions with fast convergence.

关键词： Two-phase model polymer electrolyte fuel cell Kirchhoff transformation convection dominated diffusion problem streamline diffusion Galerkin-least-squares

A vacuole localized β-glucosidase contributes to drought tolerance in Arabidopsis

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Chinese Science Bulletin 2011年第33期56卷 3538-3546页

作者： wang pengtao LIU Hao HUA HongJie wang Lei SONG Chun-Peng State Key Laboratory of Cotton Biology Laboratory of Plant Stress Biology Department of Biology Henan University Kaifeng 475004 China

The phytohormone abscisic acid (ABA) plays a critical role in plant growth, development, and adaptation to various stress conditions. The cellular ABA level is constantly adjusted to respond to changing physiological and environmental conditions. To date, the mechanisms for fine-tuning ABA levels remain elusive. Here, we report that BGLU10, a member of a multigene family of β-glucosidases, contributes to drought tolerance in Arabidopsis. The T-DNA insertion mutant bglu10 exhibited a droughtsensitive phenotype, characterized by an increased rate of water loss, and lower leaf temperature, β-glucosidase activity, ABA content, and expressions of ABA-and drought-responsive genes under drought stress. In contrast, lines overexpressing BGLU10 showed greater drought resistance than that of the wild-type, as shown by decreased water loss via transpiration, higher β-glucosidase activity, ABA level, and expressions of ABA- and stress-responsive genes under drought stress. Transient expression of BGLU10::GFP and γ-TIP1::RFP in mesophyll cell protoplasts showed that the BGLU10 enzyme protein was localized to the vacuole. Meanwhile, BGLU10 was expressed in various organs, and was induced by several abiotic stresses, suggesting that BGLU10 may be involved in a variety of stress responses, and that hydrolysis of ABA-GE produces free ABA in the plant stress response.

关键词：葡萄糖苷酶抗旱性拟南芥液泡 ABA含量本地化多基因家族干旱胁迫

Radix Achyranthis Bidentatae improves learning and memory capabilities in ovariectomized rats

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Neural Regeneration Research 2013年第18期8卷 1644-1654页

作者： Yuefen wang Ya Xu Yanshu Pan Weihong Li Wei Zhang Yang Liu Jing Jia pengtao Li Department of Encephalopathy Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine Department of Basic Chinese Medicine School of Basic Medical Sciences Beijing University of Chinese Medicine Pathology Room Department of Human Morphology School of Basic Medical Sciences Beijing University of Chinese Medicine Medical Comprehensive Course Teaching Center School of Basic Medical Sciences Beijing University of Chinese Medicine Anatomy Room Department of Human Morphology School of Basic Medical Sciences Beijing University of Chinese Medicine

Kidney-tonifying recipe can reduce the accumulation of advanced glycation end products, prevent neuronal degeneration and improve cognitive functions in ovariectomized rats. Radix Achyranthis Bidentatae alcohol extracts may dose-dependently inhibit non-enzymatic saccharification in vitro. This study aimed to examine the effect of Radix Achyranthis Bidentatae on advanced glycation end products and on learning and memory capabilities in ovariectomized rats. Ovariectomized rats were treated with Radix Achyranthis Bidentatae alcohol extracts （containing 1.5 g/kg crude drug） or 0.1% aminoguanidine for 12 weeks and behavioral testing was performed with the Y-electrical maze. This test revealed that Radix Achyranthis Bidentatae and aminoguanidine could improve the learning and memory capabilities of ovariectomized rats. Results of competitive enzyme-linked immunosorbent assay showed that treatment with Radix Achyranthis Bidentatae or aminoguanidine reduced the accumulation of advanced glycation end products in the frontal cortex of ovariectomized rats, while increasing content in the blood and urine. Biochemical tests showed that treatment with Radix Achyranthis Bidentatae or aminoguanidine decreased superoxide dismutase activity in the serum and frontal cortex, and increased serum levels of glutathione peroxidase in ovariectomized rats. In addition there was no apparent effect on malondialdehyde levels. These experimental findings indicate that Radix Achyranthis Bidentatae inhibits production of advanced glycation end products and its accumulation in brain tissue, and improves learning and memory capabilities in ovariectomized rats. These effects may be associated with an anti-oxidative action of the extract.

关键词： neural regeneration traditional Chinese medicine Alzheimer＇s disease Radix Achyranthis Bidentatae ovariectomy advanced glycation end products cognition learning and memory oxidative stress grants-supported paper neuroregeneration

Porous graphene:Properties,preparation,and potential applications

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Chinese Science Bulletin 2012年第23期57卷 2948-2955页

作者： XU pengtao YANG JiXiang wang KeSai ZHOU Zhen SHEN PanWen Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education) Institute of New Energy Material Chemistry ComputationalCenter for Molecular Science College of Chemistry Nankai University Tianjin 300071 China

Graphene has recently emerged as an important and exciting material.Inspired by its outstanding properties,many researchers have extensively studied graphene-related materials both experimentally and theoretically.Porous graphene is a collection of graphene-related materials with nanopores in the plane.Porous graphene exhibits properties distinct from those of graphene,and it has widespread potential applications in various fields such as gas separation,hydrogen storage,DNA sequencing,and supercapacitors.In this review,we summarize recent progress in studies of the properties,preparation,and potential applications of porous graphene,and show that porous graphene is a promising material with great potential for future development.

关键词： graphene porous graphene electronic structure gas separation DNA sequencing

Sustainable dropwise condensation enabled ultraefficient heat pipes

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液滴(英文) 2023年第1期2卷 64-72页

作者： Wei Chang Kai Luo pengtao wang Ahmed A.Abdulshaheed Chen Li State Key Laboratory of Automotive Simulation and Control Jilin UniversityChangchunChina Department of Thermal Engineering College of Automotive EngineeringJilin UniversityChangchunChina Department of Mechanical Engineering University of South CarolinaColumbiaSouth CarolinaUSA Oak Ridge National Laboratory Oak RidgeTennesseeUSA

Heat pipes play a critical role in determining the operations,safety,and energy efficiency of electronics.The main focus to improve the heat pipe performance is on the evaporator design or wicking structures.However,the intrinsic limitation comes from the condenser,which is fundamentally constrained by inefficient filmwise condensation(FWC).In this study,we successfully achieved a peak effective thermal conductivity(keff)of~140 kW/(m·K)on widely used groove heat pipes by implementing sustianble dropwise condensation(DWC)and integrating with enhanced evaporator.To better understand the working mechanisms of the ultraefficient heat pipe,both the evaporator and condenser of the heat pipes have been modified accordingly.Our results show that up to 296%enhancements on the keff can be achieved under various inclination angles by only inducing DWC in the condenser section.The drawback of temperature fluctuations induced by DWC in smooth heat pipes appears to be effectively solved using the grooves‐wicking structure.Furthermore,by integrating the nanostructured evaporator,the keff of the heat pipe can be boosted up to 517%compared to conventional groove heat pipes.This study,for the first time,demonstrates the huge potential of engineering both the condenser and evaporator simultaneously in developing ultraefficient heat pipes.

关键词： pipes integrating operations

知识服务视角下数字出版概念谱系的构建与拓展

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现代出版 2022年第2期 75-88页

作者：王鹏涛南京大学信息管理学院

数字出版概念的厘清是出版学理论体系建构的重要一环。对于构建数字出版的概念谱系而言,读者视角、产业视角和叙事视角都有其理论限度,而基于知识服务视角探讨数字出版在知识的生产、传播、评价、利用等过程中的作用,分析其产业边界和... 详细信息

数字出版概念的厘清是出版学理论体系建构的重要一环。对于构建数字出版的概念谱系而言,读者视角、产业视角和叙事视角都有其理论限度,而基于知识服务视角探讨数字出版在知识的生产、传播、评价、利用等过程中的作用,分析其产业边界和突围方向,进而厘清数字出版的概念谱系和逻辑关联,在学术史和学科发展的角度都显示出其创新价值。

关键词：数字出版出版业知识服务出版服务概念谱系

First Discovery of North-South Striking Normal Faults near the Potential Eastern End of Altyn Tagh Fault

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Journal of Earth Science 2018年第1期29卷 182-192页

作者： Bo Zhang Daoyang Yuan Wengui He Wei Pang pengtao wang Ming Wu Lanzhou Institute of Seismology China Earthquake Administration Lanzhou 730000 China Institute of Geology China Earthquake Administration Beijing 100029 China Second Monitoring and Application Center China Earthquake Administration Xi'an 710054 China

The Altyn Tagh fault is the northern boundary of Tibetan Plateau. As one of the most well-known strike-slip fault in the world, great achievements on tectonic deformation and Late Qua- ternary slip rate have been made. However, there is a long-lasting debate on whether the Altyn Tagh fault extends into the Jinta Basin or even eastward. In this paper, we use satellite image interpretation, field investigation, trench excavation, and optical stimulated luminescence dating to study newly found NS striking scarps in the eastern end of Jinta Nan Shan. The results are as follows： firstly, a group of normal faults develop on terrace T2 of Heihe River, the total length amounts to -40 km, total scarp height is 304-5 m; secondly, four paleoseismic events have been interpreted from three trenches, approximate ages of events are 79.97±19.14 ka BP, 62.55±13.10~55.41±10.77 ka BP, before 16.89±2.08 ka BP, 8.52±1.49 ka BP, respectively; thirdly, just like NS normal faults in the western end of Altyn Tagh fault, the newly found NS extensional faults are likely the terminating tectonics of the eastern end of Altyn Tagh fault, the large Altyn Tagh fault may end in the eastern end of Jinta Nan Shan.

关键词： Altyn Tagh fault normal fault Jinta Nan Shan fault Heihe River paleoseismic events.