检索结果-南通市图书馆

Screening the effective components in treating dampness stagnancy due to spleen deficiency syndrome and elucidating the potential mechanism of Poria water extract

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Natural Medicines 2023年第2期21卷 83-98页

作者： LI Huijun ZHANG Dandan wang Tianhe LUO Xinyao XIA Heyuan PAN Xiang HAN Sijie YOU pengtao WEI Qiong LIU Dan ZOU Zhongmei YE Xiaochuan Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine School of PharmacyHubei University of Chinese MedicineWuhan 430065China Institute of Medicinal Plant Development Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100193China

Poria is an important medicine for inducing diuresis to drain dampness from the middle energizer.However,the specific effective components and the potential mechanism of Poria remain largely unknown.To identify the effective components and the mechanism of Poria water extract(PWE)to treat dampness stagnancy due to spleen deficiency syndrome(DSSD),a rat model of DSSD was established through weight-loaded forced swimming,intragastric ice-water stimulation,humid living environment,and alternate-day fasting for 21 days.After 14 days of treatment with PWE,the results indicated that PWE increased fecal moisture percentage,urine output,D-xylose level and weight;amylase,albumin,and total protein levels;and the swimming time of rats with DSSD to different extents.Eleven highly related components were screened out using the spectrum-effect relationship and LC-MS.Mechanistic studies revealed that PWE significantly increased the expression of serum motilin(MTL),gastrin(GAS),ADCY5/6,p-PKAα/β/γcat,and phosphorylated cAMP-response element binding protein in the stomach,and AQP3 expression in the colon.Moreover,it decreased the levels of serum ADH,the expression of AQP3 and AQP4 in the stomach,AQP1 and AQP3 in the duodenum,and AQP4 in the colon.PWE induced diuresis to drain dampness in rats with DSSD.Eleven main effective components were identified in PWE.They exerted therapeutic effect by regulating the AC-cAMP-AQP signaling pathway in the stomach,MTL and GAS levels in the serum,AQP1 and AQP3 expression in the duodenum,and AQP3 and AQP4 expression in the colon.

关键词： Poria water extract Dampness stagnancy due to spleen deficiency syndrome Spectrum-effect relationship Effective components Mechanisms

An Augmented Lagrangian Uzawa IterativeMethod for Solving Double Saddle-Point Systems with Semidefinite(2,2)Block and its Application to DLM/FDMethod for Elliptic Interface Problems

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications in Computational Physics 2021年第6期30卷 124-143页

作者： Cheng wang pengtao Sun School of Mathematical Sciences Tongji UniversityShanghai 200092China Department of Mathematical Sciences University of Nevada Las Vegas4505Maryland ParkwayLas VegasNV 89154USA

.In this paper,an augmented Lagrangian Uzawa iterative method is developed and analyzed for solving a class of double saddle-point systems with semidefinite(2,2)block.Convergence of the iterativemethod is proved under the assumption that the double saddle-point problem exists a unique solution.An application of the iterative method to the double saddle-point systems arising from the distributed Lagrange multiplier/fictitious domain(DLM/FD)finite element method for solving elliptic interface problems is also presented,in which the existence and uniqueness of the double saddle-point system is guaranteed by the analysis of the DLM/FD finite element method.Numerical experiments are conducted to validate the theoretical results and to study the performance of the proposed iterative method.

关键词： Double saddle-point problem augmented Lagrangian Uzawa method elliptic interface problem distributed Lagrange multiplier/fictitious domain(DLM/FD)method

Synthesis, crystal structure and properties of a new organic-inorganic hybrid Dawson-like polyoxotungstate [Co(2,2′-bpy)_3]_2[Co(2,2′-bpy)_2Cl][Co(2,2′-bpy)_2]H_2- [SbW_(18)O_(60)]·4H_2O

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2007年第6期50卷 784-789页

作者： wang JingPing MA pengtao NIU JingYang Institute of Molecular and Crystal Engineering School of Chemistry and Chemical Engineering Henan University Kaifeng 475001 China Institute of Molecular and Crystal Engineering School of Chemistry and Chemical Engineering Henan University Kaifeng 475001 China Institute of Molecular and Crystal Engineering School of Chemistry and Chemical Engineering Henan University Kaifeng 475001 China

A new organic-inorganic hybrid polyoxometalate based on Dawson-like polyoxotungstate anion [SbW18O60]9, formulated [Co(2,2′-bpy)3]2[Co(2,2′-bpy)2Cl][Co(2,2′-bpy)2]H2[SbW18O60]·4H2O (2,2′-bpy= 2,2′-bipyridine) has been synthesized from Sb2O3, Na2WO4, CoCl2, and 2,2′-bipyridine materials by hydrothermal method, and which was characterized by elemental analyses, IR, XPS, EPR, TG, and X-ray single crystal diffraction. Structure analysis shows that the polyoxoanion self-assembled under hydrothermal conditions consists of a Dawson-like polyoxotungstate cluster anion [SbW18O60]9 en- capsulating a pyramidal {SbO3} group within the {W18} cluster cage. EPR spectra show that the high-spin octahedral CoII and low-spin CoII ions coexist in the title compound. Magnetic properties in- dicate that the compound is antiferromagnetic.

关键词： polyoxometalate, Dawson-like, crystal structure, hydrothermal synthesis

一株定植ST23-K1型耐碳青霉烯高毒力肺炎克雷伯菌的耐药性及全基因组分析

在线全文

学校读者我要写书评

暂无评论

宁夏医科大学学报 2024年第3期46卷 236-244,249页

作者：邱卓然康宇婷汪澎涛郭琴琴李秋洁贾伟宁夏医科大学总医院医学实验中心宁夏医科大学第一临床医学院银川750004 宁夏医科大学总医院医学科学研究院宁夏医科大学第一临床医学院银川750004

目的分析肺炎克雷伯菌临床分离株K63[第63号耐碳青霉烯类肺炎克雷伯菌(CRKP)]的毒力耐药情况及全基因组特征。方法收集分离自宁夏某医院新生儿重症监护室男性患儿痰液标本的肺炎克雷伯菌K63株,通过VITEK 2 Compact对其进行鉴定和药物敏... 详细信息

目的分析肺炎克雷伯菌临床分离株K63[第63号耐碳青霉烯类肺炎克雷伯菌(CRKP)]的毒力耐药情况及全基因组特征。方法收集分离自宁夏某医院新生儿重症监护室男性患儿痰液标本的肺炎克雷伯菌K63株,通过VITEK 2 Compact对其进行鉴定和药物敏感性试验。PCR法检测菌株毒力基因(ybtS、iutA、iucA、iroB、rmpA2、fimH、mrkD、peg344)和耐药基因(bla_(TEM)、bla_(SHV)、bla_(NDM)、bla_(IMP)、bla_(OXA-48)、bla_(VIM))。PacBio RSⅢ和illuminate高通量测序平台对其进行全基因组测序、基因组组装及生物信息学分析,获得菌株基因组特征。结果成功从呼吸窘迫和新生儿肺部感染患儿痰液标本中分离出一株CRKP,命名为K63。药敏结果显示其对碳青霉烯类、磺胺类、头孢菌素类、β-内酰胺类、β-内酰胺酶抑制剂复合物等抗生素均耐药。PCR结果显示,毒力基因ybtS、iucA、iutA、rmpA2、iroB、fimH、mrkD、peg344为阳性,同时携带bla_(TEM)、bla_(SHV)、bla_(NDM)及bla_(VIM)耐药基因。全基因组测序及组装得到1条完整的基因组序列及1条质粒序列,其基因组大小为5880871 bp,序列比对结果显示K63菌株为ST23-K1型。在染色体基因组基因鉴定中,发现有8种毒力基因,有7种耐药相关基因。质粒携带有bla_(SHV-66)、bla_(SNDM-5)、sul1、mphA和aph(3’)-Ia、tetC、vanA和mexe等耐药基因。clb(ABCDFGHIJKLMNOPQS)、glf、pilW、ibeB等毒力基因也被注释。同时,水平转移区域预测结果显示质粒pVir-CR-63-1具有转移的潜力。基因富集及功能分析显示主要富集于代谢相关通路。结论分离定植的K63株可能为高毒力耐碳青霉烯肺炎克雷伯菌,有潜在传播风险,临床上应予以高度重视。

关键词：碳青霉烯耐药肺炎克雷伯菌全基因组测序耐药性毒力抗生素

Molecular cytogenetic analyses of two new wheat-rye 6RL translocation lines with resistance to wheat powdery mildew

在线全文

学校读者我要写书评

暂无评论

The Crop Journal 2023年第2期11卷 584-592页

作者： Shanying Zhu Haonan Du Fuyu Su Jin wang Qingfeng Meng Tianlei Liu Rui Guo Zhaozhao Chen Huanhuan Li Wenxuan Liu pengtao Ma Huagang He School of Life Sciences Jiangsu UniversityZhenjiang 212013JiangsuChina School of Environment and Safety Engineering Jiangsu UniversityZhenjiang 212013JiangsuChina College of Life Sciences Yantai UniversityYantai 264005ShandongChina College of Life Sciences Henan Agricultural UniversityZhengzhou 450002HenanChina

Rye(Secale cereale)is a valuable gene donor for wheat improvement,especially for its resistance to diseases.Developing rye-derived resistance sources is important for wheat breeding.In the present study,two wheat-rye derivatives,designated JS016 and JS110,were produced by crossing common wheat cultivar Yangmai 23 with Pakistani rye accession W2A.Using sequential genomic in situ hybridization(GISH)and multicolor fluorescence in situ hybridization(mc-FISH),JS016 and JS110 were identified as a T6BS.6RL translocation line and a T6BS.6BL6RL translocation line,respectively.Ten newly 6RL chromosome arm-specific markers were developed and used to confirm the 6RL translocation.The wheat 55K single-nucleotide polymorphism(SNP)array further verified the molecular cytogenetic identification results above and clarified their breakpoints at 430.9 and 523.0 Mb of chromosome 6B in JS016 and JS110,respectively.Resistance spectrum and allelism test demonstrated that JS016 and JS110 possessed novel powdery mildew resistance gene(s)that was derived from the 6RL translocation but differed from Pm20.Moreover,JS016 and JS110 had better agronomic traits than the previously reported 6RL translocation line carrying Pm20.To efficiently transfer and detect the 6RL translocation from JS016 and JS110,one 6RL-specific Kompetitive allele specific PCR(KASP)marker was developed and validated in high throughput marker-assisted selection(MAS).

关键词： Secale cereale Translocation line Wheat powdery mildew GISH/FISH KASP marker

Temperature-dependent deformation in silver-particle-covered copper nanowires by molecular dynamics simulation

在线全文

学校读者我要写书评

暂无评论

Journal of Materiomics 2022年第1期8卷 68-78页

作者： pengtao Li Y.Q.Yang Vladimir Koval Xian Luo Jianxin Chen Wei Zhang E.Emily Lin Bowen wang Haixue Yan State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi'an710072China Institute of Materials Research Slovak Academy of SciencesKosice04001Slovakia School of Chemistry and Chemical Engineering Northwestern Polytechnical UniversityXi'an71072China Northwest Institute for Nonferrous Metal Research Xi'an710016China School of Engineering&Material Science Queen Mary University of LondonMile End RoadE14NSLondonUnited Kingdom

Cu nanowires covered by Ag particles is studied for potential applications in the next-generation microelectronics.To date,the deformation mechanism in the Cu-Ag core-particle is not clear.Here,molecular dynamics simulation is used to describe the Cu-Ag core-particle system.The results show that the equilibrium structure of Ag particles is reconstructed,when the particle≤1.0 nm.At low temperature(1 K)indicate that three different deformation processes take part in the core-particle structure,depending on the size of Ag particles.When the particle diameter≤2.0 nm,the prevailing deformation mechanism is the emission of dislocations from the Cu surface.For the particle diameters ranging from 3.0 to 6.0 nm,the emission of misfit dislocations from the Ag-Cu interface is the dominant deformation mechanism.If the Ag particle≥6.0 nm,the deformation mechanism can be characterized by the slip band,consisting of the dislocations and amorphous atoms.For elevated temperatures(2-400 K),the mechanical properties of the Ag-Cu core-shell system are nearly independent of temperature,whereas the structure with particles larger than 2.0 nm showed a strong dependence of its mechanical properties on temperature.Based on the results,the diameter-temperature plastic deformation map is proposed.

关键词： Nanowires Deformation Cu-Ag Nano particle Dislocation

Correction to:Modelling the response of larch growth to age,density,and elevation and the implications for multifunctional management in northwest China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

林业研究:英文版 2023年第6期34卷 2089-2090页

作者： Tian, Ao wang, Yanhui Webb, Ashley A. Yu, pengtao wang, Xiao Liu, Zebin Institute of Mountain Resource of Guizhou Province Guiyang People’s Republic of China Ecology and Nature Conservation Institute Key Laboratory of Forest Ecology and Environment of National Forestry and Grassland Administration Chinese Academy of Forestry Beijing People’s Republic of China WaterNSW Tamworth Australia

In Table 3 of the published version,“Parameters fi tted for tree height and DBH growth models of Eq.(6)”,the parameters letter mismatched the corresponding values.Hence,the authors regret that this may lead to mistakes in the tree height and DBH simulation based on the model Eq.(6).The correct Table 3 with exact parameter values is listed as follow.

关键词： larch northwest listed

CPSDv0: a forest stand structure database for plantation forests in China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Big Earth Data 2023年第1期7卷 212-230页

作者： Xiuchen Wu Xiaofei Jiang Hongyan Liu Craig Allen Xiaoyan Li Pei wang Zongshan Li Yuting Yang Shulei Zhang Fangzhong Shi Jiaojun Zhu pengtao Yu Mei Zhou Pengwu Zhao Yanhui wang Chao Yue Deliang Chen State Key Laboratory of Earth Surface Processes and Resource Ecology Beijing Normal UniversityBeijingChina School of Natural Resources Faculty of Geographical ScienceBeijing Normal UniversityBeijingChina College of Urban and Environmental Sciences and MOE Laboratory for Earth Surface Processes Peking UniversityBeijingChina U.S.Geological Survey-Nebraska Cooperative Fish&Wildlife Research Unit School of Natural Resources423 Hardin HallUniversity of NebraskaLincolnNEUSA State Key Laboratory of Urban and Regional Ecology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijingChina State Key Laboratory of Hydroscience and Engineering Department of Hydraulic EngineeringTsinghua UniversityBeijingChina CAS Key Laboratory of Forest Ecology and Management Qingyuan Forest CERNInstitute of Applied EcologyChinese Academy of SciencesShenyangChina Key Laboratory of Forest Ecology and Environment of the National Forestry and Grassland Administration of China Research Institute of Forest EcologyEnvironment and ProtectionChinese Academy of ForestryBeijingChina Academy of Forestry Inner Mongolia Agricultural UniversityHuhhotChina State Key Laboratory of Soil Erosion and Dryland Farming on the Loess Plateau Northwest A&F UniversityYanglingShaanxiChina Regional Climate Group Department of Earth SciencesUniversity of GothenburgGothenburgSweden

Forest stand structure is not only a crucial factor for regulating forest functioning but also an important indicator for sustainable forest management and ecosystem services.Although there exists a few national/global structure databases for natural forests,a country-wide synthetic structure database for plantation forests over China,the world’s largest player in plantation forests,has not been achieved.In this study,we built a country-wide synthetic stand structure database by surveying more than 600 peer-reviewed literature.The database covers tree species,mean stand age,mean tree height,stand density,canopy coverage,diameter at breast height,as well as the associated ancillary in-situ topographical and soil properties.A total of 594 pub-lished studies concerning diverse forest stand structure parameters were compiled for 46 tree species.This first synthesis for stand structure of plantation forests over China supports studies on the evolution/health of plantation forests in response to rapid climate change and intensified disturbances,and benefits country-wide sustainable forest management,future afforestation or reforestation planning.Potential users include those studying forest community dynamics,regional tree growth,ecosystem stability,and health,as well as those working with conservation and sustainable management.This dataset is freely acces-sible at http://***/10.11922/sciencedb.j00076.00091.

关键词： Stand structure plantation tree age tree height stand density canopy coverage

Confining sulfur in sandwich structure of bamboo charcoal and aluminum fluoride(BC@S@AlF3) as a long cycle performance cathode for Li-S batteries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2020年第20期52卷 159-166页

作者： Zhenya Luo Xiao wang Weixin Lei pengtao Xia Yong Pan National-Provincial Laboratory of Special Function Thin Film Materials Xiangtan UniversityXiangtanHunan 411105China School of Materials Science and Engineering Xiangtan UniversityXiangtanHunan 411105China

The ’shuttle effect’ of polysulfide causing rapid capacity fade and low coulo mbic efficiency of high ene rgy storage lithium-sulfur(Li-S) batteries.Herein,a sandwich structure of bamboo charcoal/sulfur coating by aluminum fluoride(BC@S@AlF3) composites is designed and fabricated for the first time.The as-designed cathode exhibited excellent electrochemical properties and stable capacity retention.The initial capacity reaches 1119 mA h/g and the capacity after 100 cycles is 869 mA h/g at 0.5 C,which is much stable than that of composite materials without bamboo charcoal or AlF3 coating.Moreover,the BC@S@AlF3 cathode presents excellent long-term capacity stability with a capacity decay of 0.073% per cycle during 500 charge/discharge cycles at 1 C,offering a potential for use in high energy Li-S batteries.The physical confinement,chemical ancho ring,and catalysis conversion for active sulfur are achieved simultaneously with the AlF3 coating and bamboo charcoal core with porous structure.

关键词： AlF3 coating Strong polarity Sulfur immobilizers Lithium-sulfur batteries