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Role of aminopeptidase N-like in the acquisition of begomoviruses by Bemisia tabaci,the whitefly vector

Insect Science 2024年第3期31卷 707-719页

作者： Yun-Yun Fan Yao Chi na Chen Wilmer J.Cuellar Xiao-Wei wang Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang ProvinceInstitute of Insect SciencesZhejiang UniversityHangzhouChina Zhejiang Tianmushan national nature Reserve Administration HangzhouChina Institute of Plant Protection Liaoning Academy of Agricultural SciencesShenyangChina Virology Laboratory Cassava ProgramInternational Center for Tropical Agriculture(CIAT)PalmiraColombia

Sri Lankan cassava mosaic virus(SLCMV)is a prominent causative agent of cassava mosaic disease in Asia and relies on the whitefly Bemisia tabaci cryptic complex for its ***,the molecular mechanisms involved in SLCMV transmission by *** have yet to be *** this study,we identified an aminopeptidase N-like protein(BtAPN)in *** Asia II 1,an efficient vector of SLCMV,which is involved in the SLCMV transmission *** the use of glutathione S-transferase pull-down assay and LC-MS/MS analysis,we demonstrated the interaction between BtAPN and the coat protein(CP)of *** interaction was further confirmed in vitro,and we observed an induction of BtAPN gene expression following SLCMV *** interfering with the function of BtAPN,the quantities of SLCMV were significantly reduced in various parts of *** Asia II 1,including the whole body,midgut,hemolymph,and primary salivary ***,we discovered that BtAPN is conserved in *** Middle East-Asia Minor 1(MEAM1)and interacts with the CP of tomato yellow leaf curl virus(TYLCV),a begomovirus known to cause severe damage to tomato *** BtAPN with antibody led to a significant reduction in the quantities of TYLCV in whitefly whole body and organs/*** results demonstrate that BtAPN plays a generic role in interacting with the CP of begomoviruses and positively regulates their acquisition by the whitefly.

关键词： BtAPN coat protein SLCMV TYLCV virus acquisition whitefly

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User Preference Aware Hierarchical Edge-User Cooperative Caching Strategy

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China Communications 2024年第6期21卷 69-86页

作者： Wu Dapeng Yang lin Cui Yaping He Peng wang Ruyan School of Communications and Information Engineering Chongqing University of Posts and TelecommunicationsChongqing 400065China Advanced Network and Intelligent Connection Technology Key Laboratory of Chongqing Education Commission of China Chongqing 400065China Chongqing Key Laboratory of Ubiquitous Sensing and Networking Chongqing 400065China

The emergence of various new services has posed a huge challenge to the existing network *** improve the network delay and backhaul pressure,caching popular contents at the edge of network has been considered as a feasible ***,how to efficiently utilize the limited caching resources to cache diverse contents has been confirmed as a tough problem in the past *** this paper,considering the time-varying user requests and the heterogeneous content sizes,a user preference aware hierarchical cooperative caching strategy in edge-user caching architecture is *** divide the caching strategy into three phases,that is,the content placement,the content delivery and the content *** the content placement phase,a cooperative content placement algorithm for local content popularity is designed to cache contents *** the content delivery phase,a cooperative delivery algorithm is proposed to deliver the cached *** the content update phase,a content update algorithm is proposed according to the popularity of the ***,the proposed caching strategy is validated using the MovieLens dataset,and the results reveal that the proposed strategy improves the delay performance by at least 35.3%compared with the other three benchmark strategies.

关键词： cooperative caching network delay timevarying popularity user preference

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Detour for the inexperienced? Migration count data suggest mostly juvenile Greater Spotted Eagles appear in coastal peninsulas in China

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Avian Research 2024年第2期15卷 249-254页

作者： Xu Shi Xiaoping wang Qian Wei Qiwei lin Lei Zhu School of the Environment The University of QueenslandSt LuciaQLD4072AustraliaAustralia Centre for Ecology and Conservation and Environment and Sustainability InstituteUniversity of ExeterPenrynCornwallTR109FEUK Guangxi Biodiversity Research and Conservation Association Nanning530022China Snake Island Laotieshan national nature Reserve Dalian116041China Chongqing Birdwatching Society Chongqing400054China Huqiu Rd Gusu DistrictSuzhou215008China Raptor Research Group of Chengdu Chengdu610000China Guangxi Academy of Marine Science Nanning530007China

Soaring bird migration often relies on suitable terrain and airflow;therefore,route selection is vital for successful *** age and experience have been identified as key factor influencing migration route selection among soaring raptors in the African-Eurasian Flyway,how they shape the migration route of soaring raptors in East Asia is still largely *** this study,we investigated potential variations in the routes and timing in autumn migration of juvenile and older soaring birds,using count data of Greater Spotted Eagles(Clanga clanga)from two coastal sites and two inland sites in *** 2020 to 2023,we recorded a total of 340 individuals,with the highest site averaging over 90 individuals per autumn,making it one of the world’s top single-season counts and thus a globally important site for this *** found that 82% and 61% records from coastal sites were juveniles,significantly higher than inland sites(15% and 24%).Juveniles at all four sites exhibited markedly earlier median passage time than non-juveniles,with brief overlapping in their main migration *** coastal sites are located on the tip of peninsulas stretching southwest,requiring long overwater flights if crossing the Bohai Bay or Beibu Gulf,which would be energetically demanding and increase mortality *** individuals may have learned to avoid such terrain and subsequent detour,while juveniles are more prone to enter these peninsulas due to lack of experience and opportunities for social learning,or following other raptor species that are more capable of powered *** findings highlight the importance of age and experience in migration route selection of large soaring birds.

关键词： Clanga clanga East Asia Greater Spotted Eagle Juvenile Migration route Social learning

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Characteristics and triggering mechanisms of early negative Indian Ocean Dipole

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Acta Oceanologica Sinica 2024年第3期43卷 59-65页

作者： Yue Fang Shuangwen Sun Yongcan Zu Jianhu wang lin Feng First Institute of Oceanography and Key Laboratory of Marine Science and Numerical ModelingMinistry of Natural ResourcesQingdao 266061China Laboratory for Regional Oceanography and Numerical Modeling Qingdao Marine Science and Technology CenterQingdao 266237China Shandong Key Laboratory of Marine Science and Numerical Modeling Qingdao 266061China

Negative Indian Ocean Dipole(nIOD)can exert great impacts on global climate and can also strongly influence the climate in *** nIOD is a major type of nIOD,which can induce more pronounced climate anomalies in summer than La Niña-related ***,the characteristics and triggering mechanisms of early nIOD are *** results based on reanalysis datasets indicate that the early nIOD and La Niña-related nIOD are the two major types of nIOD,and the former accounts for over one third of all the nIOD events in the past six *** two types of nIODs are similar in their intensities,but are different in their spatial patterns and seasonal *** early nIOD,which develops in spring and peaks in summer,is one season earlier than the La Niña-related *** spatial pattern of the wind anomaly associated with early nIOD exhibits a winter monsoon-like pattern,with strong westerly anomalies in the equatorial Indian Ocean and eastly anomalies in the northern Indian *** to the triggering mechanism of early positve IOD,the early nIOD is induced by delayed Indian summer monsoon *** results of this study are helpful for improving the prediction skill of IOD and its climate impacts.

关键词： Indian Ocean Dipole(IOD) triggering mechanism Indian summer monsoon seasonal cycle negative IOD

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Magnetic properties of soft magnetic composites prepared by gas-atomized glassy powders from a new Fe-based alloy with high glass-forming ability

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Science China(Physics,Mechanics & Astronomy) 2024年第11期67卷 91-104页

作者： Ranbin wang Jili Jia You Wu Wenhui Guo na Chen Yang Shao Kefu Yao School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China Wuzhen Laboratory Tongxiang 314500China

With a pressing need for high efficiency, low power consumption, and miniaturization of electronics, soft magnetic composites(SMCs) show great potential, especially for applications in key electronic component. However, core loss is still the focused issue for SMCs that hinders their sustainable development and widespread applications. In the present study, high-performance SMCs were fabricated by novel Fe_(74)B_(7)C_(7)P_(7)Si_(3)Mo_(1)Cr_(1) powders with spherical shape and a fully glassy structure, which were successfully prepared by a gas atomization method. The microstructure and high-frequency magnetic properties of these SMCs were studied in detail. To enhance the soft ferromagnetism, the effects of annealing temperature(T_a) and powder size on their performance were clarified. Increasing T_a up to 703 K not only helps to effectively release internal stress in the powders, but also improves the integrity of the insulation layer structure, which is conducive to decreasing the core loss. In addition, reducing the powder size contributes to the overall performance enhancement. Prepared from the powders with the smallest mean particle size and annealed at 703 K, the SMC exhibits optimum property combination of a stable effective permeability of 26.2 up to 1 MHz, a total core loss of 883 kW m^(–3)(100 kHz, 100 mT), and a DC-Bias performance of 79.3% under 100 Oe field, which is even comparable to those of the most prominent SMCs reported so far. These results are meaningful for potentially stimulating the development and application of new low-loss SMCs.

关键词： metallic glassy powder soft magnetic composite annealing temperature particle size high-frequency property

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Sustained release of vascular endothelial growth factor A and basic fibroblast growth factor from nanofiber membranes reduces oxygen/glucose deprivation-induced injury to neurovascular units

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Neural Regeneration Research 2024年第4期19卷 887-894页

作者： Yifang Wu Jun Sun Qi lin Dapeng wang Jian Hai Department of Neurosurgery Tongji HospitalSchool of MedicineTongji University Department of Pharmacy Institute of Medical SciencesShanghai Jiao Tong University School of Medicine

Upregulation of vascular endothelial growth factor A/basic fibroblast growth factor(VEGFA/b FGF)expression in the penumbra of cerebral ischemia can increase vascular volume,reduce lesion volume,and enhance neural cell proliferation and differentiation,thereby exerting neuroprotective ***,the beneficial effects of endogenous VEGFA/b FGF are limited as their expression is only transiently *** this study,we generated multilayered nanofiber membranes loaded with VEGFA/b FGF using layer-by-layer self-assembly and electrospinning *** found that a membrane containing 10 layers had an ideal ultrastructure and could efficiently and stably release growth factors for more than 1 *** 10-layered nanofiber membrane promoted brain microvascular endothelial cell tube formation and proliferation,inhibited neuronal apoptosis,upregulated the expression of tight junction proteins,and improved the viability of various cellular components of neurovascular units under conditions of oxygen/glucose ***,this nanofiber membrane decreased the expression of Janus kinase-2/signal transducer and activator of transcription-3(JAK2/STAT3),Bax/Bcl-2,and cleaved ***,this nanofiber membrane exhibits a neuroprotective effect on oxygen/glucose-deprived neurovascular units by inhibiting the JAK2/STAT3 pathway.

关键词： brain ischemia brain microvascular endothelial cell nanofiber membrane neurovascular unit

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Crystal engineering regulation achieving inverse temperature symmetry breaking ferroelasticity in a cationic displacement type hybrid perovskite system

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Chinese Chemical Letters 2024年第5期35卷 477-481页

作者： na wang wang Luo Huaiyi Shen Huakai Li Zejiang Xu Zhiyuan Yue Chao Shi Hengyun Ye Leping Miao Chaotic Matter Science Research Center Department of MaterialsMetallurgy and ChemistryJiangxi University of Science and TechnologyGanzhou 341000China

Ferroelastic hybrid perovskite materials have been revealed the significance in the applications of switches,sensors,actuators,***,it remains a challenge to design high-temperature ferroelastic to meet the requirements for the practical ***,we reported an one-dimensional organicinorganic hybrid perovskites(OIHP)(3-methylpyrazolium)CdCl_(3)(3-MBCC),which possesses a mmmF2/m ferroelastic phase transition at 263 ***,utilizing crystal engineering,we replace-CH_(3) with-NH_(2) and-H,which increases the intermolecular force between organic cations and inorganic *** phase transition temperature of(3-aminopyrazolium)CdCl_(3)(3-ABCC),and(pyrazolium)CdCl_(3)(BCC)increased by 73 K and 10 K,***,BCC undergoes an unconventional inverse temperature symmetry breaking(ISTB)ferroelastic phase transition around 273 ***,it transforms from a high symmetry low-temperature paraelastic phase(point group 2/m)to a low symmetry high-temperature ferroelastic phase(point group ī)originating from the rare mechanism of displacement of organic cations phase *** means that crystal BCC retains in ferroelastic phase above 273 K until melting point(446 K).Furthermore,characteristic ferroelastic domain patterns on crystal BCC are confirmed with polarized optical *** study enriches the molecular mechanism of ferroelastics in the family of organic-inorganic hybrids and opens up a new avenue for exploring high-temperature ferroic materials.

关键词： Organic-inorganic hybrid perovskite Crystal engineering Inverse temperature symmetry breaking Displacement type phase transition Ferroelasticity

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Equilibrium Reinsurance Strategy and Mean Residual Life Function

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Acta Mathematicae Applicatae Sinica 2024年第3期40卷 758-777页

作者： Dan-ping LI Lv CHEN lin-yi QIAN Wei wang School of Statistics Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOEEast China Normal UniversityShanghai 200062China Academy of Statistics and Interdisciplinary Sciences Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOEEast China Normal UniversityShanghai 200062China School of Mathematics and Statistics Ningbo UniversityNingbo 315211China

In this paper,we analyze the relationship between the equilibrium reinsurance strategy and the tail of the distribution of the *** Mean Residual Life(MRL)has a close relationship with the tail of the distribution,we consider two classes of risk distributions,Decreasing Mean Residual Life(DMRL)and Increasing Mean Residual Life(IMRL)distributions,which can be used to classify light-tailed and heavy-tailed distributions,*** assume that the underlying risk process is modelled by the classical CramérLundberg model *** the mean-variance criterion,by solving the extended Hamilton-Jacobi-Bellman equation,we derive the equilibrium reinsurance strategy for the insurer and the reinsurer under DMRL and IMRL,***,we analyze how to choose the reinsurance premium to make the insurer and the reinsurer agree with the same reinsurance *** find that under the case of DMRL,if the distribution and the risk aversions satisfy certain conditions,the insurer and the reinsurer can adopt a reinsurance premium to agree on a reinsurance strategy,and under the case of IMRL,the insurer and the reinsurer can only agree with each other that the insurer do not purchase the reinsurance.

关键词： mean residual life excess-of-loss reinsurance insurer reinsurer stochastic control

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Modulation of charge in C_(9)N_(4) monolayer for a highcapacity hydrogen storage as a switchable strategy

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Frontiers of physics 2024年第4期19卷 47-55页

作者： lin Ju Junxian Liu Minghui wang Shenbo Yang Shuli Liu School of Physics and Electric Engineering Anyang Normal UniversityAnyang 455000China School of Mechanical Medical and Process EngineeringQueensland University of TechnologyBrisbane QLD 4001Australia Hongzhiwei Technology(Shanghai)Co.Ltd. 1599 Xinjinqiao RoadPudongShanghai 201206China

Developing advanced hydrogen storage materials with high capacity and efficient reversibility is a crucial aspect for utilizing hydrogen source as a promising alternate to fossil *** this paper,we have systematically investigated the hydrogen storage properties of neutral and negatively charged C_(9)N_(4) monolayer based on density functional theory(DFT).Our foundings indicate that injecting additional electrons into the adsorbent significantly boosts the adsorption capacity of C_(9)N_(4) monolayer to H2 *** gravimetric density of negatively charged C_(9)N_(4) monolayer can reach up to 10.80 wt% when fully covered with *** other hydrogen storage methods,the storage and release processes happen automatically upon introducing or removing extra ***,these operations can be easily adjusted through activating or deactivating the charging *** a result,the method is easily reversible and has tunable kinetics without requiring particular ***,C_(9)N_(4) is proved to be a suitable candidate for efficient electron injection/release due to its well electrical *** work can serve as a valuable guide in the quest for a novel category of materials for hydrogen storage with high capacity.

关键词： hydrogen storage C_(9)N_(4)monolayer charge modulation density functional theory

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Evaluating the tumor stratification with a lysosomal pH sensitive-probe by fluorescence lifetime imaging

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Chinese Chemical Letters 2024年第3期35卷 262-267页

作者： Jun Yan Xing Liang Qian Zhang Luolin wang Weiying lin Guangxi Key Laboratory of Electrochemical Energy Materials Institute of Optical Materials and Chemical BiologySchool of Chemistry and Chemical EngineeringGuangxi UniversityNanning 530004China

Owing to the anaerobic metabolism in the tumor,abundant acidic metabolites are produced and accumulated in the ***,the cells in different tumor layers are directly linked to the pH ***,due to the lack of robust tools,the high-efficient evaluation of the acidic micro-environment of tumor stratification faces the challenge of accurate *** designed a new pH sensitive fluorescent lifetime probe target to *** we expected,the fluorescence lifetime of PLN possesses a good linear fit to the pH value,which could detect the pH change at a single lysosome level in real time,and then evaluate the different acidity of tumor *** probe PLN is successfully used to evaluate the tumor stratification by fluorescence lifetime imaging microscopy(FLIM)for the first time,which is of great significance in the preoperative diagnosis of clinical tumor treatment or evaluation of drug delivery effect.

关键词： FLIM pH Fluorescence imaging Lysosome Tumor imaging

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